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What can GP data tell us about the treatment of onychomycosis in the UK?

Sajeed, M; Wei, L; Murdan, S; (2021) What can GP data tell us about the treatment of onychomycosis in the UK? Skin Health and Disease 10.1002/ski2.84. (In press). Green open access

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Abstract

Background: Treatment of onychomycosis is challenging, and there is much literature on optimal treatment strategies. In contrast, information on how onychomycosis is actually treated in primary care is scarce. Information on practice is important as it can reveal much, such as, to what extent national guidelines are followed and which population groups seek/receive treatment or do not do so. // Objectives: To describe the pattern of onychomycosis treatment in primary care in the UK, by patient's gender and age. // Methods: A population-based retrospective cross-sectional study was conducted. The Health Improvement Network (THIN) database was used to calculate incidence rates of onychomycosis in the years 2001–2017. The prescription of oral and topical anti-fungal drugs to patients with onychomycosis was reviewed. // Results: THIN data showed an onychomycosis incidence rate of about 50 per 100,000. More males than females (52% vs. 48%), and more people aged 50–59 years had received treatment for onychomycosis. Oral terbinafine was the most commonly prescribed drug, followed by topical amorolfine, although terbinafine was used more commonly by men and amorolfine by women. Patients with onychomycosis were also prescribed other antifungals, including itraconazole, griseofulvin, tioconazole, ketoconazole shampoo, fluconazole and clotrimazole. A greater proportion of women, compared to men, were prescribed fluconazole. // Conclusions: Onychomycosis treatment in primary care in the UK is broadly in concordance with national guidelines.

Type: Article
Title: What can GP data tell us about the treatment of onychomycosis in the UK?
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/ski2.84
Publisher version: https://doi.org/10.1002/ski2.84
Language: English
Additional information: © 2021 The Authors. Skin Health and Disease published by John Wiley & Sons Ltd on behalf of British Association of Dermatologists. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharmaceutics
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Practice and Policy
URI: https://discovery.ucl.ac.uk/id/eprint/10141307
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