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Unsupervised Domain Adaptation with Semantic Consistency across Heterogeneous Modalities for MRI Prostate Lesion Segmentation

Chiou, E; Giganti, F; Punwani, S; Kokkinos, I; Panagiotaki, E; (2021) Unsupervised Domain Adaptation with Semantic Consistency across Heterogeneous Modalities for MRI Prostate Lesion Segmentation. In: Domain Adaptation and Representation Transfer, and Affordable Healthcare and AI for Resource Diverse Global Health. (pp. pp. 90-100). Springer: Cham, Switzerland. Green open access

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Abstract

Any novel medical imaging modality that differs from previous protocols e.g. in the number of imaging channels, introduces a new domain that is heterogeneous from previous ones. This common medical imaging scenario is rarely considered in the domain adaptation literature, which handles shifts across domains of the same dimensionality. In our work we rely on stochastic generative modeling to translate across two heterogeneous domains at pixel space and introduce two new loss functions that promote semantic consistency. Firstly, we introduce a semantic cycle-consistency loss in the source domain to ensure that the translation preserves the semantics. Secondly, we introduce a pseudo-labelling loss, where we translate target data to source, label them by a source-domain network, and use the generated pseudo-labels to supervise the target-domain network. Our results show that this allows us to extract systematically better representations for the target domain. In particular, we address the challenge of enhancing performance on VERDICT-MRI, an advanced diffusion-weighted imaging technique, by exploiting labeled mp-MRI data. When compared to several unsupervised domain adaptation approaches, our approach yields substantial improvements, that consistently carry over to the semi-supervised and supervised learning settings.

Type: Proceedings paper
Title: Unsupervised Domain Adaptation with Semantic Consistency across Heterogeneous Modalities for MRI Prostate Lesion Segmentation
Event: MICCAI 2021 Workshop on Domain Adaptation and Representation Transfer
ISBN-13: 978-3-030-87721-7
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/978-3-030-87722-4_9
Publisher version: https://doi.org/10.1007/978-3-030-87722-4_9
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Department of Imaging
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science
URI: https://discovery.ucl.ac.uk/id/eprint/10134725
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