Alfahad, Sarah;
(2021)
The Impact of Tooth Brushing on Teeth affected by Molar Incisor Hypomineralisation (MIH).
Doctoral thesis (D.Dent), UCL (University College London).
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Abstract
Background: Molar Incisor Hypomineralisation (MIH) can affect one or more first permanent molars (FPM), with or without the permanent incisors, prevalence ranges from 3-40%. Severity varies, and can be associated with hypersensitivity, post-eruptive breakdown (PEB) and aesthetic concerns. Different toothpastes have been suggested to enhance remineralization and reduce sensitivity, including fluoride or Novamin containing toothpastes. Aim: To compare tooth surface loss (TSL) from toothbrushing using different toothpastes in MIH affected and sound FPMs using Optical Coherence Tomography (OCT). Methods: Extracted human FPMs (N=27) Sound or with MIH were collected under ethical approval. Samples were classified using EAPD index 2014, in which type 21 indicates a white/cream opacity and type 22 yellow/brown opacity. Erosion using 1% citric acid was applied, followed by abrasion with an electric toothbrush and (i) saliva, (ii) Sensodyne® complete protection (inc Novamin), & (iii) Sensodyne® children pronamel (inc fluoride) for 100 cycles. A small needle was attached as a reference for calculation of TSL. OCT images were taken every 20 cycles, and the amount of TSL was calculated. Results: TSL was higher in children pronamel group than complete protection and saliva for MIH (type 22) and control samples, with the highest TSL 100µm and a mean of 85µm. The lowest TSL was 7µm in control group brushed with saliva. In MIH sample (type 21), the highest TSL was with Complete protection (85µm). However, the average mean of TSL for type 21 lesions with both complete protection and children pronamel groups was 45µm. Conclusion: Children Pronamel toothpaste resulted in more TSL, whereas complete protection resulted in less TSL in MIH type 22. This suggests Novamin may be beneficial in severely affected MIH teeth, but larger sample sizes are needed before a conclusion can be reached.
| Type: | Thesis (Doctoral) |
|---|---|
| Qualification: | D.Dent |
| Title: | The Impact of Tooth Brushing on Teeth affected by Molar Incisor Hypomineralisation (MIH) |
| Event: | UCL |
| Open access status: | An open access version is available from UCL Discovery |
| Language: | English |
| Additional information: | Copyright © The Author 2021. Original content in this thesis is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) Licence (https://creativecommons.org/licenses/by-nc/4.0/). Any third-party copyright material present remains the property of its respective owner(s) and is licensed under its existing terms. Access may initially be restricted at the author’s request. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10131836 |
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