Bai, F;
Tavelli, A;
Mule, G;
Falcinella, C;
Mondatore, D;
Tesoro, D;
Barbanotti, D;
... D'Arminio Monforte, A; + view all
(2021)
A Quantitative Estimate of the Expected Shortening of the Median Isolation Period of Patients With COVID-19 After the Adoption of a Symptom-Based Strategy.
Frontiers in Public Health
, 9
, Article 639347. 10.3389/fpubh.2021.639347.
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Abstract
A long period of isolation was observed in patients hospitalized for COVID-19 in Milan over March-September 2020 (45; IQR: 37–54 days). A significantly shorter period would have been observed by the application of May-WHO (22, IQR: 17–30 days, P < 0.001) and October-Italian (26, IQR: 21–34 days, P < 0.001) Guidelines. The adoption of the new symptom-based criteria is likely to lead to a significant reduction in the length of the isolation period with potential social, economic and psychological benefits, particularly in the younger population with mild/moderate disease and no comorbidities. In our opinion, the release from isolation after 21 days from symptoms onset, even without a PCR diagnostic test, in most cases seems the most adequate strategy that could balance precautions to prevent SARS CoV-2 transmission and unnecessary prolonged isolation or overuse of diagnostic testing.
| Type: | Article |
|---|---|
| Title: | A Quantitative Estimate of the Expected Shortening of the Median Isolation Period of Patients With COVID-19 After the Adoption of a Symptom-Based Strategy |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3389/fpubh.2021.639347 |
| Publisher version: | https://doi.org/10.3389/fpubh.2021.639347 |
| Language: | English |
| Additional information: | © 2021 Bai, Tavelli, Mulè, Falcinella, Mondatore, Tesoro, Barbanotti, Tomasoni, Castoldi, Augello, Allegrini, Tagliaferri, Cona, Cozzi-Lepri, Marchetti and d'Arminio Monforte. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). |
| Keywords: | COVID-19, SARS CoV-2, molecular diagnosis, isolation and quarantine, criteria for releasing COVID-19 patients from isolation |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health > Infection and Population Health |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10131134 |
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