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An integrative developmental psychopathology approach to depression

Luyten, P; Fonagy, P; (2022) An integrative developmental psychopathology approach to depression. In: Jiménez, JP and Botto, A and Fonagy, P, (eds.) Etiopathogenic Theories and Models in Depression. (pp. 245-263). Springer: Cham, Switzerland. Green open access

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Abstract

This chapter aims to describe an integrative developmental psychopathology approach to the conceptualization and treatment of depression. Based on evolutionary and developmental psychopathology approaches, we discuss empirical findings concerning three biobehavioral systems that are central in depression: stress or emotion regulation, reward, and mentalizing or social cognition. We discuss interrelated disturbances in each of these biobehavioral systems and how they typically lead to developmental cascades involved in depression. We focus on the impact of these interacting impairments on normative developmental tasks that rely on capacities associated with each of the three biobehavioral systems. We highlight the importance of adolescence and early adulthood, as these developmental phases involve the need to establish a new balance between relatedness and agency/autonomy, capacities that rely heavily on the stress-regulation, reward, and mentalizing systems. We also discuss how this approach sheds a new light on the high comorbidity between depression and other psychiatric and (functional) somatic disorders. Finally, we consider the implications of these views for prevention and intervention approaches.

Type: Book chapter
Title: An integrative developmental psychopathology approach to depression
ISBN-13: 978-3-030-77328-1
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/978-3-030-77329-8_13
Publisher version: https://doi.org/10.1007/978-3-030-77329-8_13
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
Keywords: Depression, Stress, Reward, Mentalizing, Development
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
URI: https://discovery.ucl.ac.uk/id/eprint/10129807
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