Gallo, B;
Al-Jamal, RT;
Thaung, C;
Cohen, VML;
(2020)
Iris extramedullary hematopoiesis in choroidal melanoma.
Saudi Journal of Ophthalmology
, 34
(2)
pp. 82-84.
10.4103/1319-4534.305034.
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Abstract
PURPOSE: Extramedullary hematopoiesis (EMH) usually occurs in patients with loss of bone marrow hematopoietic function, and in a vast majority of cases, it involves the liver, the spleen, or the lymph nodes. We report EMH in the iris of patients enucleated for choroidal melanoma (CM). METHODS: We report a series of three patients with CM, two treated with primary enucleation and one with secondary enucleation. RESULTS: Histopathology revealed EMH in the iris of all patients. CONCLUSION: EMH of the iris can be associated with CM in the absence of any hematological or systemic disorders. To the best of our knowledge, our work is the first report of this abnormal histopathological finding.
| Type: | Article |
|---|---|
| Title: | Iris extramedullary hematopoiesis in choroidal melanoma |
| Location: | India |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.4103/1319-4534.305034 |
| Publisher version: | http://www.saudijophthalmol.org/article.asp?issn=1... |
| Language: | English |
| Additional information: | © 2020 Saudi Journal of Ophthalmology. This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution‑NonCommercial‑ShareAlike 4.0 License (https://creativecommons.org/licenses/by-nc-sa/4.0/). |
| Keywords: | Choroidal melanoma, enucleation, iris extramedullary hematopoiesis |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10122248 |
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