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Probiotic design

Beckett, R; (2021) Probiotic design. The Journal of Architecture , 26 (1) pp. 6-31. 10.1080/13602365.2021.1880822. Green open access

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Abstract

Responding to advances in medical fields that now understand the integral role that bacteria play towards human health, this research proposes a novel probiotic approach towards designing healthy buildings in relation to beneficial microbes. This research fundamentally challenges modern approaches to healthy buildings that assume fewer microbes as the default healthy condition. Probiotic design builds on the contemporary understanding of the microbiome and the need for reintroducing environmental microbial diversity into buildings. The research uses an interdisciplinary approach between microbiology and architecture which aims to develop living materials embedded with beneficial bacteria for buildings to directly shape the indoor microbiome towards a healthier microbial condition. This approach utilises a mix of in vitro and in silico methodologies to explore the design, fabrication, and survival of living probiotic materials. These are then scaled up to building size as a series of probiotic tile surfaces which are in turn installed in a test space to monitor their effect on the indoor microbiome. The research provides evidence of a successful methodology for integrating viable bacteria into ceramic and concrete materials. As these are proved to inhibit the growth of pathogens, they can also directly increase environmental microbial presence towards healthy indoor microbiomes.

Type: Article
Title: Probiotic design
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/13602365.2021.1880822
Publisher version: https://doi.org/10.1080/13602365.2021.1880822
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of the Built Environment
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of the Built Environment > The Bartlett School of Architecture
URI: https://discovery.ucl.ac.uk/id/eprint/10122048
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