Pouw, JJ;
Fratila, RM;
Velders, AH;
ten Haken, B;
Pankhurst, QA;
Klaase, JM;
(2012)
Ex vivo magnetic sentinel lymph node detection in colorectal cancer with a SPIO tracer.
In:
Magnetic Particle Imaging.
(pp. pp. 181-185).
Springer: Springer, Berlin, Heidelberg.
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Abstract
A new method for selecting sentinel lymph nodes (SNs) in colorectal cancer tissue was investigated in 12 patients. A tracer consisting of superparamagnetic ironoxide (SPIO) nanoparticles was injected in the resected tissue. A handheld magnetic probe was used to select SNs to which the SPIO was drained. Vibrating sample magnetometry was performed on the lymph nodes to quantify the amount of SPIO in the nodes. High-field MRI allowed to depict the distribution of SPIO in the node, and revealed small anatomical structures. One or more SPIO containing nodes were successfully selected with the magnetic probe in all 12 patients.
| Type: | Proceedings paper |
|---|---|
| Title: | Ex vivo magnetic sentinel lymph node detection in colorectal cancer with a SPIO tracer |
| ISBN-13: | 9783642241321 |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/978-3-642-24133-8_29 |
| Publisher version: | https://doi.org/10.1007/978-3-642-24133-8_29 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10116972 |
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