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Global COVID-19 pandemic demands joint interventions for the suppression of future waves

Li, R; Chen, B; Zhang, T; Ren, Z; Song, Y; Xiao, Y; Hou, L; ... Xu, B; + view all (2020) Global COVID-19 pandemic demands joint interventions for the suppression of future waves. Proceedings of the National Academy of Sciences of the United States of America , 117 (42) pp. 26151-26157. 10.1073/pnas.2012002117. Green open access

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Abstract

Emerging evidence suggests a resurgence of COVID-19 in the coming years. It is thus critical to optimize emergency response planning from a broad, integrated perspective. We developed a mathematical model incorporating climate-driven variation in community transmissions and movement-modulated spatial diffusions of COVID-19 into various intervention scenarios. We find that an intensive 8-wk intervention targeting the reduction of local transmissibility and international travel is efficient and effective. Practically, we suggest a tiered implementation of this strategy where interventions are first implemented at locations in what we call the Global Intervention Hub, followed by timely interventions in secondary high-risk locations. We argue that thinking globally, categorizing locations in a hub-and-spoke intervention network, and acting locally, applying interventions at high-risk areas, is a functional strategy to avert the tremendous burden that would otherwise be placed on public health and society.

Type: Article
Title: Global COVID-19 pandemic demands joint interventions for the suppression of future waves
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1073/pnas.2012002117
Publisher version: https://doi.org/10.1073/pnas.2012002117
Language: English
Additional information: Copyright © 2020 the Author(s). Published by PNAS. This open access article is distributed under Creative Commons Attribution License 4.0 (CC BY) (http://creativecommons.org/licenses/by/4.0/).
Keywords: climate, human behavior, disease transmission, hierarchical intervention network, international collaboration
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of the Built Environment
URI: https://discovery.ucl.ac.uk/id/eprint/10114137
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