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Cytogenetic variation in British house mice

Brooker, Paul Charles; (1990) Cytogenetic variation in British house mice. Doctoral thesis (Ph.D), UCL (University College London). Green open access

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The data presented in this thesis consist of an examination of chromosomal variation in British house mice. Mice from a wide range of habitats were examined, ranging from Taunton in Somerset to various islands in the Shetland group. Following an introduction to the subject material and a chapter concerned with materials and methods used, three chapters study in detail three different aspects of chromosomal variation. The first (chapter 3) involves a description of mice in Scotland that demonstrate centric fusion of their chromosomes. This occurs in the mainland county of Caithness and some , but not all , Orkney islands. This process is termed "Robertsonian translocation" and is the first British example of a phenomenon that has been seen in wild mice from other countries. Chapter 4 describes an examination of six populations of mice for variation in the number and pattern of chiasma in male meiotic chromosomes. Chapter 5 describes an examination of a number of populations of mice for variation in the quantity of centromeric heterochromatin as measured by C-bands. An attempt is made to quantify C-band variation. Finally chapter 6 returns to the topic of Robertsonian translocations and discusses the data generated in the light of population genetics theory and cytogenetic theories of speciation.

Type: Thesis (Doctoral)
Qualification: Ph.D
Title: Cytogenetic variation in British house mice
Open access status: An open access version is available from UCL Discovery
Language: English
Additional information: Thesis digitised by ProQuest.
Keywords: Biological sciences; Cytogenetics
URI: https://discovery.ucl.ac.uk/id/eprint/10111103
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