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Multiparametric MR characterisation of a high-fat, high-cholesterol diet rodent model of liver disease

Chouhan, M; Bray, T; Connell, J; McNaughton, J; Bainbridge, A; Jones, H; Habtiesen, A; ... Taylor, S; + view all (2017) Multiparametric MR characterisation of a high-fat, high-cholesterol diet rodent model of liver disease. In: Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM). The 25th Annual Meeting & Exhibition: One Community for Clinicians and Scientists. Mira Smart Conference Green open access

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Abstract

There is a growing interest in the development of new animal models of non-alcoholic fatty liver disease. In this study, we use T1, proton density fat fraction (PDFF) and R2* mapping to characterise hepatic parenchymal tissue and the evolution of MR properties over time in a high-fat, high-cholesterol diet model of fatty liver disease.

Type: Proceedings paper
Title: Multiparametric MR characterisation of a high-fat, high-cholesterol diet rodent model of liver disease
Event: ISMRM 2017. The 25th Annual Meeting & Exhibition: One Community for Clinicians and Scientists
Location: Honululu, Hawaii
Open access status: An open access version is available from UCL Discovery
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Department of Imaging
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Experimental and Translational Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inst for Liver and Digestive Hlth
URI: https://discovery.ucl.ac.uk/id/eprint/10109343
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