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Post-stimulatory activity in primate auditory cortex evoked by sensory stimulation during passive listening

Cooke, JE; Lee, JJ; Bartlett, EL; Wang, X; Bendor, D; (2020) Post-stimulatory activity in primate auditory cortex evoked by sensory stimulation during passive listening. Scientific Reports , 10 , Article 13885. 10.1038/s41598-020-70397-0. Green open access

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Abstract

Under certain circumstances, cortical neurons are capable of elevating their fring for long durations in the absence of a stimulus. Such activity has typically been observed and interpreted in the context of performance of a behavioural task. Here we investigated whether post-stimulatory activity is observed in auditory cortex and the medial geniculate body of the thalamus in the absence of any explicit behavioural task. We recorded spiking activity from single units in the auditory cortex (felds A1, R and RT) and auditory thalamus of awake, passively-listening marmosets. We observed poststimulatory activity that lasted for hundreds of milliseconds following the termination of the acoustic stimulus. Post-stimulatory activity was observed following both adapting, sustained and suppressed response profles during the stimulus. These response types were observed across all cortical felds tested, but were largely absent from the auditory thalamus. As well as being of shorter duration, thalamic post-stimulatory activity emerged following a longer latency than in cortex, indicating that post-stimulatory activity may be generated within auditory cortex during passive listening. Given that these responses were observed in the absence of an explicit behavioural task, post-stimulatory activity in sensory cortex may play a functional role in processes such as echoic memory and temporal integration that occur during passive listening.

Type: Article
Title: Post-stimulatory activity in primate auditory cortex evoked by sensory stimulation during passive listening
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/s41598-020-70397-0
Publisher version: https://doi.org/10.1038/s41598-020-70397-0
Language: English
Additional information: This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Experimental Psychology
URI: https://discovery.ucl.ac.uk/id/eprint/10108943
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