UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

The effects of adding transcutaneous Spinal Cord Stimulation (tSCS) to Sit-to-Stand training in people with Spinal Cord Injury: A pilot study

Al'Joboori, Y; Massey, S; Knight, SL; Donaldson, N; Duffell, L; (2020) The effects of adding transcutaneous Spinal Cord Stimulation (tSCS) to Sit-to-Stand training in people with Spinal Cord Injury: A pilot study. Journal of Clinical Medicine , 9 (9) , Article 2765. 10.3390/jcm9092765. Green open access

[thumbnail of Duffell_vor_Al'joboori et al. 2020 JCM.pdf]
Preview
Text
Duffell_vor_Al'joboori et al. 2020 JCM.pdf - Published Version

Download (3MB) | Preview

Abstract

Spinal cord stimulation may enable recovery of volitional motor control in people with chronic Spinal Cord Injury (SCI). In this study we explored the effects of adding SCS, applied transcutaneously (tSCS) at vertebral levels T10/11, to a sit-to-stand training intervention in people with motor complete and incomplete SCI. Nine people with chronic SCI (six motor complete; three motor incomplete) participated in an 8-week intervention, incorporating three training sessions per week. Participants received either tSCS combined with sit-to-stand training (STIM) or sit-to-stand training alone (NON-STIM). Outcome measures were carried out before and after the intervention. Seven participants completed the intervention (STIM N = 5; NON-STIM N = 2). Post training, improvements in International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) motor scores were noted in three STIM participants (range 1.0–7.0), with no change in NON-STIM participants. Recovery of volitional lower limb muscle activity and/or movement (with tSCS off) was noted in three STIM participants. Unassisted standing was not achieved in any participant, although standing with minimal assistance was achieved in one STIM participant. This pilot study has shown that the recruitment of participants, intervention and outcome measures were all feasible in this study design. However, some modifications are recommended for a larger trial.

Type: Article
Title: The effects of adding transcutaneous Spinal Cord Stimulation (tSCS) to Sit-to-Stand training in people with Spinal Cord Injury: A pilot study
Open access status: An open access version is available from UCL Discovery
DOI: 10.3390/jcm9092765
Publisher version: https://doi.org/10.3390/jcm9092765
Language: English
Additional information: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Keywords: human; neuromodulation; neurorehabilitation; non-invasive; spinal cord injury; transcutaneous spinal cord stimulation
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10108337
Downloads since deposit
48Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item