Li, V;
Barker, N;
Curtis, C;
Porter, B;
Panicker, JN;
Chataway, J;
Pakzad, M;
(2020)
The prevention and management of hospital admissions for urinary tract infection in patients with multiple sclerosis.
Multiple Sclerosis and Related Disorders
, 45
, Article 102432. 10.1016/j.msard.2020.102432.
Preview |
Text
Chataway_200717 MS rUTI MSARD clean.pdf - Accepted Version Download (972kB) | Preview |
Abstract
Introduction Urinary tract infections (UTIs) are one of the commonest reasons for patients with multiple sclerosis (PwMS) presenting to hospital. Management of recurrent UTIs in PwMS can be challenging and characteristics of such patients are not well described. Aims To describe the neurological and urological features of PwMS presenting to hospital for UTIs and identify areas of management that could be improved to reduce UTI frequency. Methods Health episode statistics data were used to identify PwMS presenting to a tertiary hospital with UTI over a 5-year period. Medical records were reviewed for demographic, MS and urological history. The seven PwMS with the highest numbers of encounters were seen in a multidisciplinary clinic to enable detailed assessments. Results 52 PwMS (25 female, 27 male) with mean age of 60 had 112 emergency department presentations and 102 inpatient admissions for UTI. 24 presented multiple times and were more likely to be older and male with progressive MS. Almost two-thirds were using a urinary catheter. Less than half were under current urological and neurological follow-up. Escherichia coli and Pseudomonas spp were the commonest organisms cultured. Resistance to antibiotics was more frequent in patients with multiple presentations. Conclusions PwMS presenting to hospital for UTIs are more often male, older, with progressive MS and high levels of disability. A small group of PwMS accounted for a large number of encounters. Preventative and management strategies can be applied in primary and secondary care settings, with an emphasis on bladder, catheter and general physical care.
| Type: | Article |
|---|---|
| Title: | The prevention and management of hospital admissions for urinary tract infection in patients with multiple sclerosis |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.msard.2020.102432 |
| Publisher version: | https://doi.org/10.1016/j.msard.2020.102432 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10107070 |
Archive Staff Only
 |
View Item |
