Olaru, ID;
Meierkord, A;
Godman, B;
Ngwenya, C;
Fitzgerald, F;
Dondo, V;
Ferrand, RA;
(2020)
Assessment of antimicrobial use and prescribing practices among pediatric inpatients in Zimbabwe.
Journal of Chemotherapy
, 32
(8)
pp. 456-459.
10.1080/1120009X.2020.1734719.
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Abstract
This study aims to assess antimicrobial consumption in the pediatric department of a tertiary care public hospital in Zimbabwe. Clinical records of pediatric inpatients admitted to Harare Central Hospital over a 3-week period were reviewed prospectively. Antimicrobial consumption was described as days of therapy per 100 inpatient days (DOT/100 PD). Adherence of antimicrobial drug prescriptions to the National Guidelines was also evaluated. A total of 121 (93.1%) children were prescribed at least one antimicrobial out of 130 children admitted. The median age was 14 months (IQR: 3 - 48 months). Overall antimicrobial consumption was 155.4 DOT/100 PD (95% CI 146-165.2). The most frequently prescribed antimicrobials were benzylpenicillin, gentamicin and ceftriaxone. Prescriptions were adherent to national guidelines in 57.7% of children. This study shows that there is high antimicrobial drug usage in hospitalized children in Zimbabwe and a considerable proportion of prescriptions are non-adherent with national guidelines.
| Type: | Article |
|---|---|
| Title: | Assessment of antimicrobial use and prescribing practices among pediatric inpatients in Zimbabwe |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1080/1120009X.2020.1734719 |
| Publisher version: | https://doi.org/10.1080/1120009X.2020.1734719 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | AMR, Antibiotic resistance, Antimicrobial consumption, Antimicrobial resistance, Antimicrobial stewardship, Children |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Infection, Immunity and Inflammation Dept |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10094845 |
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