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High energy x-ray implementation of phase contrast and dark field imaging

Buchanan, Ian; (2020) High energy x-ray implementation of phase contrast and dark field imaging. Doctoral thesis (Ph.D), UCL (University College London). Green open access

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Abstract

X-ray phase contrast and dark field imaging are emerging imaging modalities which provide significantly enhanced visibility of details classically considered “x-ray invisible” and complementary information on a sample’s micro-structure, respectively. To date they have been successfully implemented in a series of applications at low x-ray energy, but their translation to higher x-ray energies is still, to some extent, problematic. Yet the ability to perform phase contrast and dark field imaging at high x-ray energy would have a series of significant implications in various applications, medical or otherwise. This thesis work investigates this option through a combination of modelling and experimental work. Particular attention has been dedicated to the behaviour of the optical elements (x-ray masks) that make phase contrast and dark field possible at high energy, which required the design of new methods of their implemention into simulation models. The modeling results have been validated first through a pilot experiment at a synchrotron facility, then in a series of lab experiments. Results clearly indicate that implementations of phase contrast and dark field imaging at high x-ray energy exist, however particular care must be taken in the design and fabrication of the masks; moreover, a series of parasitic effects which are absent at lower energies appear, which this thesis work describes and against which it suggests mitigation solutions.

Type: Thesis (Doctoral)
Qualification: Ph.D
Title: High energy x-ray implementation of phase contrast and dark field imaging
Event: UCL
Open access status: An open access version is available from UCL Discovery
Language: English
Additional information: Copyright © The Author 2020. Original content in this thesis is licensed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) Licence (https://creativecommons.org/licenses/by/4.0/). Any third-party copyright material present remains the property of its respective owner(s) and is licensed under its existing terms. Access may initially be restricted at the author’s request.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10091153
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