Ramaswami, U;
Humphries, SE;
Priestley-Barnham, L;
Green, P;
Wald, DS;
Capps, N;
Anderson, M;
... Morris, AA; + view all
(2019)
Current management of children and young people with heterozygous familial hypercholesterolaemia - HEART UK statement of care.
Atherosclerosis
, 290
pp. 1-8.
10.1016/j.atherosclerosis.2019.09.005.
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Abstract
This consensus statement on the management of children and young people with heterozygous familial hypercholesterolaemia (FH) addresses management of paediatric FH in the UK, identified by cascade testing when a parent is diagnosed with FH and for those diagnosed following incidental lipid tests. Lifestyle and dietary advice appropriate for children with FH; suggested low density lipoprotein cholesterol (LDL-C) targets and the most appropriate lipid-lowering therapies to achieve these are discussed in this statement of care. Based on the population prevalence of FH as ~1/250 and the UK paediatric population, there are approximately 50,000 FH children under 18 years. Currently only about 550 of these children and young people have been identified and are under paediatric care.
| Type: | Article |
|---|---|
| Title: | Current management of children and young people with heterozygous familial hypercholesterolaemia - HEART UK statement of care |
| Location: | Ireland |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.atherosclerosis.2019.09.005 |
| Publisher version: | https://doi.org/10.1016/j.atherosclerosis.2019.09.... |
| Language: | English |
| Additional information: | © 2019 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/). |
| Keywords: | Children and young people, Familial hypercholesterolaemia, Heterozygous familial hypercholesterolaemia, Lifestyle advice, Statin treatment |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10082605 |
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