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Semi-automatic Vendor-Independent Software for Assessment of Local Arterial Stiffness

Negoita, M; Abdullateef, S; Khir, AW; Hughes, AD; Parker, KH; (2019) Semi-automatic Vendor-Independent Software for Assessment of Local Arterial Stiffness. In: Dassen, Willem and Heijman, Jordi, (eds.) Proceedings of the 2018 Computing in Cardiology Conference (CinC). IEEE Xplore: New York, USA. Green open access

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Abstract

Background: Stiffened arteries represent a major cardiovascular risk. // Aim: We describe a vendor independent software for the non-invasive determination of arterial stiffness using ultrasound images. // Methods: We have developed an intensity-based semiautomatic software for determining the edges of the luminal arterial walls (M-mode) and blood velocity (PW Doppler) to extract diameter and velocity waveform from ultrasound images. The upstroke of the two waveforms is automatically determined as well as the fit of the initial linear portion of the ln(D)U-loop. Pulse wave velocity (PWV), which is proportional to the slope of ln(D)U-loop during early systole is calculated as a measure of arterial stiffness. The user can over-ride and correct the automatically determined parameters if necessary. // Results: A semi-automatic code was developed for tracing the luminal diameter and blood velocity in the human ascending aorta. D and U waveforms were extracted and used in ln(D)U-loops to calculate PWV. // Conclusions: The software described here can be used to assess, local aortic stiffness non-invasively, by using ultrasound measurements/images of the diameter and velocity waveforms.

Type: Proceedings paper
Title: Semi-automatic Vendor-Independent Software for Assessment of Local Arterial Stiffness
Event: 2018 Computing in Cardiology Conference (CinC), 23-26 Sept 2018, Maastricht, Netherlands
ISBN-13: 9781728109589
Open access status: An open access version is available from UCL Discovery
DOI: 10.22489/CinC.2018.218
Publisher version: https://doi.org/10.22489/CinC.2018.218
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: biomechanics, biomedical ultrasonics, blood vessels, cardiovascular system, diseases, elastic constants, haemodynamics
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Population Science and Experimental Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10079204
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