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Low-density lipoprotein cholesterol and suicidal behaviour in a large sample of first-episode psychosis patients

Ayesa-Arriola, R; Canal Rivero, M; Delgado-Alvarado, M; Setién-Suero, E; González-Gómez, J; Labad, J; David, AS; (2018) Low-density lipoprotein cholesterol and suicidal behaviour in a large sample of first-episode psychosis patients. The World Journal of Biological Psychiatry , 19 (sup3) S158-S161. 10.1080/15622975.2017.1414305. Green open access

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Abstract

Increased risk of death by suicide has been reported in First Episode Psychosis (FEP) patients. Low concentrations of lipids have been associated with suicidality and violent suicide methods. The aims were to analyse the relationship between lipid profile at baseline with suicidality and suicide methods in a sample of 332 antipsychotic-naïve FEP patients. Depressive symptomatology (OR=1.15, 95% CI=1.06-1.24) and low LowDensity lipoproteins (LDL) (OR=0.99, 95% CI= 0.98-1.00) were significantly related with suicidal behaviour. Patients who used violent suicide methods did not show significant low levels of lipoproteins. Low LDL could be considered in the assessment of suicide risk.

Type: Article
Title: Low-density lipoprotein cholesterol and suicidal behaviour in a large sample of first-episode psychosis patients
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/15622975.2017.1414305
Publisher version: https://doi.org/10.1080/15622975.2017.1414305
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: lipoproteins, first episode psychosis, schizophrenia, suicide, LDL, HDL
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
URI: https://discovery.ucl.ac.uk/id/eprint/10076235
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