Patwardhan, A;
Brandt, R;
Butcher, SJ;
Collinson, L;
Gault, D;
Grunewald, K;
Hecksel, C;
... Kleywegt, GJ; + view all
(2017)
Cutting Edge: Building bridges between cellular and molecular structural biology.
eLife
, 6
, Article e25. 10.7554/eLife.25835.
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Abstract
The integration of cellular and molecular structural data is key to understanding the function of macromolecular assemblies and complexes in their in vivo context. Here we report on the outcomes of a workshop that discussed how to integrate structural data from a range of public archives. The workshop identified two main priorities: the development of tools and file formats to support segmentation (that is, the decomposition of a three-dimensional volume into regions that can be associated with defined objects), and the development of tools to support the annotation of biological structures.
| Type: | Article |
|---|---|
| Title: | Cutting Edge: Building bridges between cellular and molecular structural biology |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.7554/eLife.25835 |
| Publisher version: | https://doi.org/10.7554/eLife.25835 |
| Language: | English |
| Additional information: | This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication (http://creativecommons.org/publicdomain/zero/1.0/). |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Structural and Molecular Biology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10073385 |
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