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The ‘ALSPAC in London’ dataset: adiposity, cardiometabolic risk profiles, and the emerging arterial phenotype in young adulthood [version 1; referees: awaiting peer review]

Chiesa, STC; Rapala, A; Charakida, M; Wade, K; Timpson, N; Deanfield, J; (2018) The ‘ALSPAC in London’ dataset: adiposity, cardiometabolic risk profiles, and the emerging arterial phenotype in young adulthood [version 1; referees: awaiting peer review]. Wellcome Open Research , 3 (162) 10.12688/wellcomeopenres.14942.1. Green open access

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Abstract

Rising rates of adiposity in the young pose one of the greatest threats to future population burden of cardiovascular disease. Understanding the contribution of genetic and early-life influences to adiposity profiles in young adulthood – when the first signs of subclinical cardiovascular disease commonly appear – are vital if effective lifetime prevention strategies are to be developed. This data note documents the extensive range of genotypic and phenotypic data available from a London-based sub-study of the long-running Avon Longitudinal Study of Parents and Children (ALSPAC)—the ‘ALSPAC in London’ Study—in which extensive adipose and cardiovascular phenotyping was carried out in participants recruited based on a genetic predisposition to obesity.

Type: Article
Title: The ‘ALSPAC in London’ dataset: adiposity, cardiometabolic risk profiles, and the emerging arterial phenotype in young adulthood [version 1; referees: awaiting peer review]
Open access status: An open access version is available from UCL Discovery
DOI: 10.12688/wellcomeopenres.14942.1
Publisher version: https://doi.org/10.12688/wellcomeopenres.14942.1
Language: English
Additional information: © 2018 Chiesa ST et al. This is an open access article distributed under the terms of the Creative Commons Attribution Licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: Adiposity, cardiometabolic risk, arterial phenotypes, ALSPAC
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science > Clinical Science
URI: https://discovery.ucl.ac.uk/id/eprint/10065025
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