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In vivo phase imaging of human epiphyseal cartilage at 7 T

Dymerska, B; Bohndorf, K; Schennach, P; Rauscher, A; Trattnig, S; Robinson, SD; (2018) In vivo phase imaging of human epiphyseal cartilage at 7 T. Magnetic Resonance in Medicine , 79 (4) pp. 2149-2155. 10.1002/mrm.26858. Green open access

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Abstract

PURPOSE: To assess the potential clinical utility of in vivo susceptibility-weighted imaging and quantitative susceptibility mapping of growth cartilage in the juvenile human knee at 7 T. METHODS: High-resolution gradient-echo images of the knees of six healthy children and adolescents aged 6 to 15 were acquired with a 28-channel coil at 7 T. Phase images from the coils were combined using a short echo-time reference scan method (COMPOSER). RESULTS: Veins oriented perpendicular to the static B0field appeared doubled in susceptibility-weighted imaging, but not quantitative susceptibility mapping. Veins and layers in the cartilage were visible in all children up to the age of 13. CONCLUSION: Phase imaging using susceptibility-weighted imaging and quantitative susceptibility mapping allows the in vivo visualization of veins and layers in human growth cartilage.

Type: Article
Title: In vivo phase imaging of human epiphyseal cartilage at 7 T
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/mrm.26858
Publisher version: https://doi.org/10.1002/mrm.26858
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: quantitative susceptibility mapping, susceptibility‐weighted imaging, phase, cartilage, epiphyseal cartilage, veins, layers
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Imaging Neuroscience
URI: https://discovery.ucl.ac.uk/id/eprint/10064376
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