Fassati, A;
(2006)
HIV infection of non-dividing cells: a divisive problem.
Retrovirology
, 3
, Article 74. 10.1186/1742-4690-3-74.
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Abstract
Understanding how lentiviruses can infect terminally differentiated, non-dividing cells has proven a very complex and controversial problem. It is, however, a problem worth investigating, for it is central to HIV-1 transmission and AIDS pathogenesis. Here I shall attempt to summarise what is our current understanding for HIV-1 infection of non-dividing cells. In some cases I shall also attempt to make sense of controversies in the field and advance one or two modest proposals.
| Type: | Article |
|---|---|
| Title: | HIV infection of non-dividing cells: a divisive problem |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1186/1742-4690-3-74 |
| Publisher version: | http://dx.doi.org/10.1186/1742-4690-3-74 |
| Language: | English |
| Additional information: | © 2006 Fassati; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | Human-Immunodeficiency-Virus, Nuclear-Pore Complex, Murine Leukemia-Virus, Reverse transcription complexes, Avian-Sarcoma virus, Central DNA flap, Viral matrix protein, CD4(+) T-Cells, Type-1 Preintegration Complexes, Macrophage infection |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity |
| URI: | https://discovery.ucl.ac.uk/id/eprint/100581 |
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