Thapar, N;
Borrelli, O;
(2018)
Anorectal Manometry for the Diagnosis of Hirschsprung Disease: New Heights for the Balloon or Just Hot Air?
Journal of Pediatric Gastroenterology and Nutrition
10.1097/MPG.0000000000002076.
(In press).
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Abstract
In this issue of the Journal of Pediatric Gastroenterology and Nutrition, Meinds et al (1) report on the performance of a modified anorectal manometry (ARM) protocol for the diagnosis of Hirschsprung Disease (HSCR). In a prospective study of 105 patients suspected of having HSCR they showed that both the sensitivity and specificity of their modified ARM protocol were equivalent to rectal suction biopsy (RSB) with a 100% negative predictive value. They conclude that ARM is a viable screening tool for HSCR and could be used as a first diagnostic step to exclude HSCR across all age groups and ultimately reduce the need for rectal biopsies.
| Type: | Article |
|---|---|
| Title: | Anorectal Manometry for the Diagnosis of Hirschsprung Disease: New Heights for the Balloon or Just Hot Air? |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1097/MPG.0000000000002076 |
| Publisher version: | http://dx.doi.org/10.1097/MPG.0000000000002076 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10053389 |
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