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Anorectal Manometry for the Diagnosis of Hirschsprung Disease: New Heights for the Balloon or Just Hot Air?

Thapar, N; Borrelli, O; (2018) Anorectal Manometry for the Diagnosis of Hirschsprung Disease: New Heights for the Balloon or Just Hot Air? Journal of Pediatric Gastroenterology and Nutrition 10.1097/MPG.0000000000002076. (In press). Green open access

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Abstract

In this issue of the Journal of Pediatric Gastroenterology and Nutrition, Meinds et al (1) report on the performance of a modified anorectal manometry (ARM) protocol for the diagnosis of Hirschsprung Disease (HSCR). In a prospective study of 105 patients suspected of having HSCR they showed that both the sensitivity and specificity of their modified ARM protocol were equivalent to rectal suction biopsy (RSB) with a 100% negative predictive value. They conclude that ARM is a viable screening tool for HSCR and could be used as a first diagnostic step to exclude HSCR across all age groups and ultimately reduce the need for rectal biopsies.

Type: Article
Title: Anorectal Manometry for the Diagnosis of Hirschsprung Disease: New Heights for the Balloon or Just Hot Air?
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1097/MPG.0000000000002076
Publisher version: http://dx.doi.org/10.1097/MPG.0000000000002076
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10053389
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