UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Enhancing the Magnetic Heating Capacity of Iron Oxide Nanoparticles through Their Postproduction Incorporation into Iron Oxide-Gold Nanocomposites

Bell, G; Bogart, LK; Southern, P; Olivo, M; Pankhurst, QA; Parkin, IP; (2017) Enhancing the Magnetic Heating Capacity of Iron Oxide Nanoparticles through Their Postproduction Incorporation into Iron Oxide-Gold Nanocomposites. European Journal of Inorganic Chemistry (18) pp. 2386-2395. 10.1002/ejic.201601432. Green open access

[thumbnail of Bogart_Enhancing the Magnetic Heating Capacity of Iron Oxide Nanoparticles through Their Postproduction Incorporation into Iron Oxide-Gold Nanocomposites accepted version.pdf]
Preview
Text
Bogart_Enhancing the Magnetic Heating Capacity of Iron Oxide Nanoparticles through Their Postproduction Incorporation into Iron Oxide-Gold Nanocomposites accepted version.pdf - Accepted Version

Download (2MB) | Preview

Abstract

Small variations in the synthesis conditions of iron oxide–gold nanocomposites, made in an aqueous medium by a coprecipitation reaction, have a significant effect on the magnetic‐heating properties of the iron oxide nanoparticles. Citric acid coated magnetite/maghemite (Fe3O4/γ‐Fe2O3) nanoparticles were used as a Turkevich‐style reducing agent and added to varying concentrations of HAuCl4 to form iron oxide–gold nanoparticle composites with Fe/Au molar ratios ranging from ca. 5:1 to ca. 300:1. The magnetic‐heating capacities of the products were measured in a high‐frequency alternating field (peak amplitude 6.6 kA/m, frequency 967 kHz), to determine both the specific absorption rates (SARs) and the intrinsic loss powers (ILPs) of the products. The iron oxide (FeOx) precursor presented a moderately high SAR of 33.9 W/gFeOx and an ILP of 0.8 nH m2/kgFeOx, but the iron oxide–gold nanocomposite formed with 0.75 mm HAuCl4 had an almost threefold‐enhanced heating capacity with a SAR of 88.3 W/gFeOx and an ILP of 2.1 nH m2/kgFeOx. This corresponds to an ILP of 3.0 nH m2/kgFe, which is as high as that of any commercially available material to date. This result has implications for the possible postproduction enhancement of the magnetic‐heating capacities of similar iron oxide systems as well as increasing the theranostic potential of such materials through the incorporation of Au nanoparticles, which may act as integrated binding sites for drugs or other beneficial biomolecules.

Type: Article
Title: Enhancing the Magnetic Heating Capacity of Iron Oxide Nanoparticles through Their Postproduction Incorporation into Iron Oxide-Gold Nanocomposites
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/ejic.201601432
Publisher version: http://dx.doi.org/10.1002/ejic.201601432
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Science & Technology, Physical Sciences, Chemistry, Inorganic & Nuclear, Chemistry, Iron, Gold, Nanoparticles, Nanostructures, Magnetic properties, Magnetic hyperthermia, COMPOSITE NANOPARTICLES, MOSSBAUER-SPECTROSCOPY, STEM-CELLS, DELIVERY, SHELL, MRI
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Chemical Engineering
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/10049456
Downloads since deposit
219Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item