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Comparison of outcomes after UKA in patients with and without chondrocalcinosis: a matched cohort study

Kumar, V; Pandit, HG; Liddle, AD; Borror, W; Jenkins, C; Mellon, SJ; Hamilton, TW; ... Murray, DW; + view all (2017) Comparison of outcomes after UKA in patients with and without chondrocalcinosis: a matched cohort study. Knee Surgery, Sports Traumatology, Arthroscopy , 25 (1) pp. 319-324. 10.1007/s00167-015-3578-8. Green open access

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Abstract

Purpose: Chondrocalcinosis can be associated with an inflammatory arthritis and aggressive joint destruction. There is uncertainty as to whether chondrocalcinosis represents a contraindication to unicompartmental knee arthroplasty (UKA). This study reports the outcome of a consecutive series of patients with chondrocalcinosis and medial compartment osteoarthritis treated with UKA matched to controls. Methods: Between 1998 and 2008, 88 patients with radiological chondrocalcinosis (R-CCK) and 67 patients with histological chondrocalcinosis (H-CCK) were treated for end-stage medial compartment arthritis with Oxford UKA. One-to-two matching was performed to controls, treated with UKA, but without evidence of chondrocalcinosis. Functional outcome and implant survival were assessed in each group. Results: The mean follow-up was 10 years. The mean Oxford Knee Score (OKS) at final follow-up was 43, 41 and 41 in H-CCK, R-CCK and control groups (change from baseline OKS was 21, 18 and 15, respectively). The change was significantly higher in H-CCK than in control but was not significantly different in R-CCK. Ten-year survival was 96 % in R-CCK, 86 % in H-CCK and 98 % in controls. Although the survival in H-CCK was significantly worse than in control, only one failure was due to disease progression. Conclusion: The presence of R-CCK does not influence functional outcome or survival following UKA. Pre-operative radiological evidence of CCK should not be considered to be a contraindication to UKA. H-CCK is associated with significantly improved clinical outcomes but also a higher revision rate compared with controls. Level of evidence: Case control study, Level III.

Type: Article
Title: Comparison of outcomes after UKA in patients with and without chondrocalcinosis: a matched cohort study
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s00167-015-3578-8
Publisher version: http://doi.org/10.1007/s00167-015-3578-8
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Unicompartmental knee replacement, Chondrocalcinosis, Patient-reported outcome, Implant survival
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute
URI: https://discovery.ucl.ac.uk/id/eprint/10046664
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