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Integrating MRI for the diagnosis of prostate cancer

Moore, CM; Taneja, SS; (2016) Integrating MRI for the diagnosis of prostate cancer. Current Opinion in Urology , 26 (5) pp. 466-471. 10.1097/MOU.0000000000000323. Green open access

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Abstract

Purpose of review We review recent developments in prostate MRI for prostate cancer diagnosis. Recent findings Large series have strengthened the case for the use of MRI prior to subsequent biopsy to maximize the detection of clinically significant disease, and reduce the detection of clinically insignificant disease. This has effectively moved the discussion on from whether MRI is useful in prostate cancer detection to how best to use it, and at which time point. The Prostate Imaging- Reporting And Data System (PIRADS) group have published a second version of the PIRADS criteria for prostate MRI, covering acquisition, interpretation, and reporting both for clinical practice and data collection for research. There is debate about the commonly used and more prescriptive PIRADS system versus the less prescriptive systems based on overall clinical impression of clinically significant disease (e.g. Likert or simplified quantum scoring). Studies suggest that the Likert or simplified quantum scoring approach may outperform PIRADSv2. Published data are conflicting on whether software-assisted fusion of MRI lesions to ultrasound used at biopsy is more effective than visual registration by a trained operator. Summary The use of prostate MRI is increasing worldwide, and the debate now focuses on how best to use it to optimize the detection of clinically significant disease.

Type: Article
Title: Integrating MRI for the diagnosis of prostate cancer
Open access status: An open access version is available from UCL Discovery
DOI: 10.1097/MOU.0000000000000323
Publisher version: https://doi.org/10.1097/MOU.0000000000000323
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Science & Technology, Life Sciences & Biomedicine, Urology & Nephrology, multiparametric MRI, prostate cancer, prostate cancer detection, screening, RESONANCE-ULTRASOUND FUSION, MULTI-PARAMETRIC MRI, GUIDED BIOPSY, GUIDANCE, SYSTEM, MEN
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Targeted Intervention
URI: https://discovery.ucl.ac.uk/id/eprint/10043597
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