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Rifampicin resistance in tuberculosis outbreak, London, England

Jenkins, C; Claxton, AP; Shorten, RJ; McHugh, TD; Gillespie, SH; (2005) Rifampicin resistance in tuberculosis outbreak, London, England. EMERG INFECT DIS , 11 (6) 931 - 934. Green open access

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Abstract

Mycobacterium tuberculosis isolates cultured from 6 patients associated with an isoniazid-resistant M. tuberculosis outbreak acquired rifampicin resistance. The rpoB gene sequence showed that resistance was associated with rare mutations in each isolate. Three isolates had a mutation outside the rifampicin resistance-determining region.

Type: Article
Title: Rifampicin resistance in tuberculosis outbreak, London, England
Open access status: An open access version is available from UCL Discovery
Publisher version: http://www.cdc.gov/ncidod/eid/index.htm
Keywords: LINE PROBE ASSAY, MYCOBACTERIUM-TUBERCULOSIS, RPOB GENE, MUTATIONS
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
URI: https://discovery.ucl.ac.uk/id/eprint/7006
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