Vardakis, IC;
Guo, L;
Chou, D;
Tully, BJ;
Vindedal, GF;
Jensen, V;
Thoren, AE;
... Ventikos, Y; + view all
(2017)
Poroelastic Modelling of CSF circulation via the incorporation of experimentally derived microscale water transport properties.
In: Nithiarasu, P and Robertson, AM, (eds.)
Proceedings of the 5th International Conference on Computational & Mathematical Biomedical Engineering (CMBE 2017), Volume 2.
(pp. pp. 773-776).
Zeta Computational Resources Ltd: Swansea, UK.
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Abstract
We outline how multicompartmental poroelasticity is applied to the study of dementia. We utilize a 3D version of our poroelastic code to investigate the effects within parenchymal tissue. This system is coupled with multiple pipelines within the VPH-DARE@IT project which account for patient/subject-specific boundary conditions in the arterial compartment, in addition to both an image segmentation-mesh and integrated cardiovascular system model pipeline respectively. This consolidated template allows for the extraction of boundary conditions to run CFD simulations for the ventricles. Finally, we outline some experimental results that will help inform the MPET system.
Type: | Proceedings paper |
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Title: | Poroelastic Modelling of CSF circulation via the incorporation of experimentally derived microscale water transport properties |
Event: | CMBE17: 5th International Conference on Computational & Mathematical Biomedical Engineering, 10 - 12 April 2017, Pittsburgh, USA |
Location: | Pittsburgh, USA |
Dates: | 10 April 2017 - 12 April 2017 |
ISBN-13: | 9780956291448 |
Open access status: | An open access version is available from UCL Discovery |
Publisher version: | http://www.compbiomed.net/2017/cmbe-proceedings.ht... |
Language: | English |
Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
Keywords: | Dementia, Poroelasticity, Cerebrospinal Fluid, Glymphatic system, CFD, FEM |
UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering |
URI: | https://discovery.ucl.ac.uk/id/eprint/1573538 |
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