Vassileva, V;
Rajkumar, V;
Mazzantini, M;
Robson, M;
Badar, A;
Sharma, S;
Årstad, E;
... Pedley, RB; + view all
(2015)
Significant Therapeutic Efficacy with Combined Radioimmunotherapy and Cetuximab in Preclinical Models of Colorectal Cancer.
Journal of Nuclear Medicine
, 56
(8)
pp. 1239-1245.
10.2967/jnumed.115.157362.
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J Nucl Med-2015-Vassileva-1239-45.pdf Access restricted to UCL open access staff Download (1MB) |
Abstract
Despite extensive efforts to improve the clinical management of patients with colorectal cancer, approved treatments for advanced disease offer limited survival benefit. Therefore, the identification of novel treatment strategies is essential. We evaluated the preclinical efficacy of combination radioimmunotherapy, using a humanized (131)I-labeled anti-carcinoembryonic antigen antibody ((131)I-huA5B7), with cetuximab in colorectal cancer (CRC).
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