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Primary Sclerosing Cholangitis and Psychological Wellbeing: A Scoping Review

Ranieri, V; McKay, K; Walmsley, M; Senior, R; Thorburn, D; Kennedy, E; (2019) Primary Sclerosing Cholangitis and Psychological Wellbeing: A Scoping Review. Seminars in Liver Disease , 39 (1) pp. 104-110. 10.1055/s-0038-1676099. Green open access

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Abstract

Primary sclerosing cholangitis (PSC) is a chronic liver disease resulting from the inflammation and scarring of an individual's hepatic bile ducts. With no curative treatment available and a risk of potentially severe complications and death, it is likely that those diagnosed with the illness may experience impairments in their psychological wellbeing. The aim of this scoping review is to locate, chart, and summarize all available literature on how PSC affects mental health and psychological wellbeing, as well as the factors that may or may not impact on the psychological wellbeing of those who have this diagnosis. This exercise identified five key themes within the literature: prevalence and characteristics of mental health problems, quality of life, unmet needs, medical treatment, and biomarkers. Three key recommendations for clinical practice emerge from this review.

Type: Article
Title: Primary Sclerosing Cholangitis and Psychological Wellbeing: A Scoping Review
Open access status: An open access version is available from UCL Discovery
DOI: 10.1055/s-0038-1676099
Publisher version: https://doi.org/10.1055/s-0038-1676099
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: primary sclerosing cholangitis, mental health, psychological wellbeing, scoping review
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10069596
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