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Reconceiving egg freezing: insights from an analysis of 5 years of data from a UK clinic

Gurtin, ZB; Shah, T; Wang, J; Ahuja, K; (2019) Reconceiving egg freezing: insights from an analysis of 5 years of data from a UK clinic. Reproductive BioMedicine Online , 38 (2) pp. 272-282. 10.1016/j.rbmo.2018.11.003. Green open access

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Abstract

Research question What can we learn from 5 years of egg-freezing practice in the UK? What are the different categories of egg freezing, and what are the social and demographic characteristics of patients, and their decisions regarding subsequent storage or thawing? Design A retrospective analysis of clinical and laboratory data of all 514 cycles of ‘own’ egg freezing conducted at the London Women’s Clinic in the 5-year period from the start of 2012 to the end of 2016. Results This analysis, the first of its kind, develops a clearer picture of egg-freezing trends in the UK and fills in the details behind the Human Fertilisation and Embryology Authority’s national figures. Four different categories of egg freezing are identified and the appropriate category allocated to each of the 514 cycles undertaken by 352 patients. To the established categories of ‘medical’ and ‘social’ already discussed in the literature, we add the two new categories of ‘clinical’ and ‘incidental’ egg freezing. We show how each of these categories presents a distinct egg-freezing patient profile, and discuss the similarities and differences between them across variables such as age, relationship status, number of eggs frozen, number of egg-freezing cycles undertaken, and the current status of frozen eggs. Conclusions The data require a reconceptualization of the phenomenon of egg freezing, and argue for the importance of clearly and accurately differentiating between different categories of egg-freezing practice in clinical and national data collection in order to adequately inform future practice, regulation and the decision-making processes of patients considering these procedures.

Type: Article
Title: Reconceiving egg freezing: insights from an analysis of 5 years of data from a UK clinic
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.rbmo.2018.11.003
Publisher version: https://doi.org/10.1016/j.rbmo.2018.11.003
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Science & Technology, Life Sciences & Biomedicine, Obstetrics & Gynecology, Reproductive Biology, Egg freezing, Ethics, Fertility preservation, Oocyte cryopreservation, Regulation, Sociology of assisted reproduction, OOCYTE CRYOPRESERVATION
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health
URI: https://discovery.ucl.ac.uk/id/eprint/10069267
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