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A multi-center study on fast full-brain quantitative multi-parameter mapping of R1, MT, and R2*: scan-rescan repeatability and inter-site reproducibility

Seif, M; Leutritz, T; Samson, R; Curt, A; Wheeler-Kingshott, CAM; Freund, P; Weiskopf, N; (2018) A multi-center study on fast full-brain quantitative multi-parameter mapping of R1, MT, and R2*: scan-rescan repeatability and inter-site reproducibility. In: Proceedings of the Joint Annual Meeting ISMRM-ESMRMB 2018. (pp. p. 1198). International Society for Magnetic Resonance in Medicine (ISMRM): Paris, France. Green open access

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Abstract

We present a multi-center, multi-vendor study evaluating repeatability and reproducibility of quantitative MRI data acquired using high resolution (1 mm³) multi-parameter mapping which provides quantitative R1, MT and R2* maps of the whole brain within less than 18 min. The protocol was implemented at four clinical sites with different Siemens and Philips 3T MRI scanners. Scan-rescan measurements of the same five healthy volunteers at all sites showed good intra-site reproducibility in all parameter maps. However, the inter-site comparisons showed higher reproducibility within a single vendor than across vendors.

Type: Proceedings paper
Title: A multi-center study on fast full-brain quantitative multi-parameter mapping of R1, MT, and R2*: scan-rescan repeatability and inter-site reproducibility
Event: Joint Annual Meeting ISMRM-ESMRMB 2018
Location: Paris
Dates: 15 June 2018 - 18 March 2018
Open access status: An open access version is available from UCL Discovery
Publisher version: https://www.ismrm.org/18/program_files/Th07.htm
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Department of Neuromuscular Diseases
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neuroinflammation
URI: https://discovery.ucl.ac.uk/id/eprint/10045182
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