Browse by UCL people
Group by: Type | Date
Number of items: 38.
2024
Da Cruz, Lyndon;
Soomro, Taha;
Georgiadis, Odysseas;
Nommiste, Britta;
Sagoo, Mandeep S;
Coffey, Peter;
(2024)
The Fate of RPE Cells Following hESC-RPE Patch Transplantation in Haemorrhagic Wet AMD: Pigmentation, Extension of Pigmentation, Thickness of Transplant, Assessment for Proliferation and Visual Function—A 5 Year-Follow Up.
Diagnostics
, 14
(10)
, Article 1005. 10.3390/diagnostics14101005.
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Liu, Jian;
Copland, David A;
Clare, Alison J;
Gorski, Mathias;
Richards, Burt T;
Scott, Louis;
Theodoropoulou, Sofia;
... Dick, Andrew D; + view all
(2024)
Replenishing IRAK-M expression in retinal pigment epithelium attenuates outer retinal degeneration.
Science Translational Medicine
, 16
(750)
, Article eadi4125. 10.1126/scitranslmed.adi4125.
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2023
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Raza, Zara;
Hussain, Syeda F;
Foster, Victoria S;
Wall, Joseph;
Coffey, Peter J;
Martin, John F;
Gomes, Renata SM;
(2023)
Exposure to war and conflict: The individual and inherited epigenetic effects on health, with a focus on post-traumatic stress disorder.
Frontiers in Epidemiology
, 3
, Article 1066158. 10.3389/fepid.2023.1066158.
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2020
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Bailey-Steinitz, LJ;
Shih, Y-H;
Radeke, MJ;
Coffey, PJ;
(2020)
An in vitro model of chronic wounding and its implication for age-related macular degeneration.
PLoS ONE
, 15
(7)
10.1371/journal.pone.0236298.
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Vitillo, L;
Tovell, VE;
Coffey, P;
(2020)
Treatment of Age-Related Macular Degeneration with Pluripotent Stem Cell-Derived Retinal Pigment Epithelium.
Current Eye Research
, 45
(3)
pp. 361-371.
10.1080/02713683.2019.1691237.
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2019
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Eastlake, K;
Wang, W;
Jayaram, H;
Murray-Dunning, C;
Carr, AJF;
Ramsden, CM;
Vugler, A;
... Limb, GA; + view all
(2019)
Phenotypic and Functional Characterization of Müller Glia Isolated from Induced Pluripotent Stem Cell-Derived Retinal Organoids: Improvement of Retinal Ganglion Cell Function upon Transplantation.
Stem Cells Translational Medicine
, 8
(8)
pp. 775-784.
10.1002/sctm.18-0263.
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Sarkar, H;
Mitsios, A;
Smart, M;
Skinner, J;
Welch, A;
Kalatzis, V;
Coffey, P;
... Moosajee, M; + view all
(2019)
Nonsense-mediated mRNA decay efficiency varies in choroideremia providing a target to boost small molecule therapeutics.
Human Molecular Genetics
, 28
(11)
pp. 1865-1871.
10.1093/hmg/ddz028.
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Toh, H;
Smolentsev, A;
Bozadjian, RV;
Keeley, PW;
Lockwood, MD;
Sadjadi, R;
Clegg, DO;
... Thomson, JA; + view all
(2019)
Vascular changes in diabetic retinopathy-a longitudinal study in the Nile rat.
Laboratory Investigation
, 99
pp. 1547-1560.
10.1038/s41374-019-0264-3.
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2018
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da Cruz, L;
Fynes, K;
Georgiadis, O;
Kerby, J;
Luo, YH;
Ahmado, A;
Vernon, A;
... Coffey, PJ; + view all
(2018)
Phase 1 clinical study of an embryonic stem cell-derived retinal pigment epithelium patch in age-related macular degeneration.
Nature Biotechnology
, 36
(4)
pp. 328-337.
10.1038/nbt.4114.
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Eastlake, K;
Wang, W;
Ramsden, C;
Murray-Dunning, C;
Khaw, PT;
Coffey, P;
Limb, A;
(2018)
Isolation and propagation of Müller glia from human iPSC and ESC derived retinal organoids.
Presented at: ARVO Annual Meeting 2018, Honolulu, Hawaii,.
(In press).
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Nommiste, B;
Vaino, I;
Radeke, MJ;
Nymark, S;
Coffey, PJ;
Carr, A-JF;
(2018)
A cellular disease model system of ARB: The creation of iPS-RPE from a patient with a premature stop mutation (p.R200X).
Presented at: Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu, HI.
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Stacey, G;
Andrews, PW;
Asante, C;
Barbaric, I;
Barry, J;
Bisset, L;
Braybrook, J;
... Williams, D; + view all
(2018)
Science-based assessment of source materials for cell-based medicines: report of a stakeholders workshop.
Regenerative Medicine
, 13
(8)
pp. 935-944.
10.2217/rme-2018-0120.
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2017
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Nommiste, B;
Fynes, K;
Tovell, VE;
Ramsden, C;
da Cruz, L;
Coffey, P;
(2017)
Stem cell-derived retinal pigment epithelium transplantation for treatment of retinal disease.
Progress in Brain Research
, 231
pp. 225-244.
10.1016/bs.pbr.2017.03.003.
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Ramsden, C;
(2017)
Using stem cells to model MERTK deficient retinis pigmentosa.
Doctoral thesis (Ph.D), UCL (University College London).
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Ramsden, CM;
Nommiste, B;
R Lane, A;
Carr, AF;
Powner, MB;
J K Smart, M;
Chen, LL;
... Coffey, PJ; + view all
(2017)
Rescue of the MERTK phagocytic defect in a human iPSC disease model using translational read-through inducing drugs.
Scientific Reports
, 7
(1)
, Article 51. 10.1038/s41598-017-00142-7.
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Schwarz, N;
Lane, A;
Jovanovic, K;
Parfitt, DA;
Aguila, M;
Thompson, CL;
da Cruz, L;
... Cheetham, ME; + view all
(2017)
Arl3 and RP2 regulate the trafficking of ciliary tip kinesins.
[Corrigendum].
Human Molecular Genetics
, 26
(17)
p. 3451.
10.1093/hmg/ddx245.
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Schwarz, N;
Lane, A;
Jovanovich, K;
Parfitt, DA;
Aguila, M;
Thompson, CL;
da Cruz, L;
... Cheetham, ME; + view all
(2017)
Arl3 and RP2 regulate the trafficking of ciliary tip kinesins.
Human Molecular Genetics
, 26
(13)
pp. 2480-2492.
10.1093/hmg/ddx143.
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2016
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Carter, DA;
Nommiste, B;
Coffey, PJ;
Carr, AF;
(2016)
Spontaneous Generation of Patient-Specific Retinal Pigment Epithelial Cells Using Induced Pluripotent Stem Cell Technology.
In: Ulrich, U and Davidson Negraes, P, (eds.)
Working with Stem Cells.
(pp. 143-161).
Springer: Cham, Switzerland.
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Carter, DA;
Smart, MJK;
Letton, WVG;
Ramsden, CM;
Nommiste, B;
Chen, LL;
Fynes, K;
... Carr, A-JF; + view all
(2016)
Mislocalisation of BEST1 in iPSC-derived retinal pigment epithelial cells from a family with autosomal dominant vitreoretinochoroidopathy (ADVIRC).
Scientific Reports
, 6
, Article 337. 10.1038/srep33792.
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Moosajee, M;
Tracey-White, D;
Smart, M;
Weetall, M;
Torriano, S;
Kalatzis, V;
da Cruz, L;
... Welch, E; + view all
(2016)
Functional rescue of REP1 following treatment with PTC124 and novel derivative PTC-414 in human choroideremia fibroblasts and the nonsense-mediated zebrafish model.
Human Molecular Genetics
, 25
(16)
pp. 3416-3431.
10.1093/hmg/ddw184.
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Nommiste, B;
(2016)
A Model System Of Autosomal-Recessive Bestrophinopathy.
Doctoral thesis , UCL (University College London).
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Parfitt, DA;
Lane, A;
Ramsden, C;
Jovanovic, K;
Coffey, PJ;
Hardcastle, AJ;
Cheetham, ME;
(2016)
Using induced pluripotent stem cells to understand retinal ciliopathy disease mechanisms and develop therapies.
Biochemical Society Transactions
, 44
(5)
pp. 1245-1251.
10.1042/BST20160156.
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Parfitt, DA;
Lane, A;
Ramsden, CM;
Carr, A-JF;
Munro, PM;
Jovanovic, K;
Schwarz, N;
... Cheetham, ME; + view all
(2016)
Identification and Correction of Mechanisms Underlying Inherited Blindness in Human iPSC-Derived Optic Cups.
Cell Stem Cell
, 18
(6)
pp. 769-781.
10.1016/j.stem.2016.03.021.
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Semo, M;
Coffey, P;
Gias, C;
Vugler, A;
(2016)
Retrograde Melanopsin Signaling Increases With Age in Retinal Degenerate Mice Lacking Rods and the Majority of Cones.
Investigative Ophthalmology & Visual Science
, 57
(1)
pp. 115-125.
10.1167/iovs.15-17609.
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Semo, M;
Haamedi, N;
Stevanato, L;
Carter, D;
Brooke, G;
Young, M;
Coffey, P;
... Vugler, A; + view all
(2016)
Efficacy and Safety of Human Retinal Progenitor Cells.
Translational Vision Science & Technology
, 5
(4)
, Article 6. 10.1167/tvst.5.4.6.
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2015
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Schwarz, N;
Carr, AJ;
Lane, A;
Moeller, F;
Chen, LL;
Aguilà, M;
Nommiste, B;
... Hardcastle, AJ; + view all
(2015)
Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells.
Hum Mol Genet
, 24
(4)
972 - 986.
10.1093/hmg/ddu509.
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Vugler, A;
Semo, M;
Ortín-Martínez, A;
Rojanasakul, A;
Nommiste, B;
Valiente-Soriano, FJ;
García-Ayuso, D;
... Gias, C; + view all
(2015)
A role for the outer retina in development of the intrinsic pupillary light reflex in mice.
Neuroscience
, 286
60 - 78.
10.1016/j.neuroscience.2014.11.044.
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Yvon, C;
Ramsden, CM;
Lane, A;
Powner, MB;
da Cruz, L;
Coffey, PJ;
Carr, AJ;
(2015)
Using Stem Cells to Model Diseases of the Outer Retina.
Computational and Structural Biotechnology Journal
, 13
pp. 382-389.
10.1016/j.csbj.2015.05.001.
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2014
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Aguilà, M;
Bevilacqua, D;
McCulley, C;
Schwarz, N;
Athanasiou, D;
Kanuga, N;
Novoselov, SS;
... Cheetham, ME; + view all
(2014)
Hsp90 inhibition protects against inherited retinal degeneration.
Hum Mol Genet
, 23
(8)
pp. 2164-2175.
10.1093/hmg/ddt613.
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Muthiah, MN;
Gias, C;
Chen, FK;
Zhong, J;
McClelland, Z;
Sallo, FB;
Peto, T;
... da Cruz, L; + view all
(2014)
Cone photoreceptor definition on adaptive optics retinal imaging.
British Journal of Opthalmology
, 98
(8)
1073 - 1079.
10.1136/bjophthalmol-2013-304615.
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Parfitt, DA;
Aguila, M;
McCulley, CH;
Bevilacqua, D;
Mendes, HF;
Athanasiou, D;
Novoselov, SS;
... Cheetham, ME; + view all
(2014)
The heat-shock response co-inducer arimoclomol protects against retinal degeneration in rhodopsin retinitis pigmentosa.
Cell Death Dis
, 5
, Article e1236. 10.1038/cddis.2014.214.
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2013
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Catchpole, I;
Germaschewski, V;
Kam, JH;
von Leithner, PL;
Ford, S;
Gough, G;
Adamson, P;
... Jeffery, G; + view all
(2013)
Systemic Administration of Abeta mAb Reduces Retinal Deposition of Abeta and Activated Complement C3 in Age-Related Macular Degeneration Mouse Model.
PLOS ONE
, 8
(6)
, Article e65518. 10.1371/journal.pone.0065518.
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Goh, PA;
Caxaria, S;
Casper, C;
Rosales, C;
Warner, TT;
Coffey, PJ;
Nathwani, AC;
(2013)
A Systematic Evaluation of Integration Free Reprogramming Methods for Deriving Clinically Relevant Patient Specific Induced Pluripotent Stem (iPS) Cells.
PLoS One
, 8
(11)
, Article e81622. 10.1371/journal.pone.0081622.
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Lidster, K;
Jackson, SJ;
Ahmed, Z;
Munro, P;
Coffey, P;
Giovannoni, G;
Baker, MD;
(2013)
Neuroprotection in a Novel Mouse Model of Multiple Sclerosis.
PLoS One
, 8
(11)
, Article e79188. 10.1371/journal.pone.0079188.
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2010
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Brown, TM;
Gias, C;
Hatori, M;
Keding, SR;
Semo, M;
Coffey, PJ;
Gigg, J;
... Lucas, RJ; + view all
(2010)
Melanopsin Contributions to Irradiance Coding in the Thalamo-Cortical Visual System.
PLOS BIOL
, 8
(12)
, Article e1000558. 10.1371/journal.pbio.1000558.
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Semo, M;
Gias, C;
Ahmado, A;
Sugano, E;
Allen, AE;
Lawrence, JM;
Tomita, H;
... Vugler, AA; + view all
(2010)
Dissecting a Role for Melanopsin in Behavioural Light Aversion Reveals a Response Independent of Conventional Photoreception.
PLOS ONE
, 5
(11)
, Article e15009. 10.1371/journal.pone.0015009.
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2009
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Carr, AJ;
Vugler, AA;
Hikita, ST;
Lawrence, JM;
Gias, C;
Chen, LL;
Buchholz, DE;
... Coffey, PJ; + view all
(2009)
Protective Effects of Human iPS-Derived Retinal Pigment Epithelium Cell Transplantation in the Retinal Dystrophic Rat.
PLOS ONE
, 4
(12)
, Article e8152. 10.1371/journal.pone.0008152.
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Franzco, FKC;
Uppal, GS;
MacLaren, RE;
Coffey, PJ;
Rubin, GS;
Tufail, A;
Aylward, GW;
(2009)
Long-term visual and microperimetry outcomes following autologous retinal pigment epithelium choroid graft for neovascular age-related macular degeneration.
CLIN EXP OPHTHALMOL
, 37
(3)
275 - 285.
10.1111/j.1442-9071.2009.01915.x.
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