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A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome

Wiseman, FK; Al-Janabi, T; Hardy, J; Karmiloff-Smith, A; Nizetic, D; Tybulewicz, VLJ; Fisher, EMC; (2015) A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome. Nature Reviews Neuroscience , 16 (9) pp. 564-574. 10.1038/nrn3983. Green open access

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Type: Article
Title: A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/nrn3983
Publisher version: http://dx.doi.org/10.1038/nrn3983
Language: English
Additional information: Copyright © 2015 Macmillan Publishers Limited.
Keywords: Science & Technology, Life Sciences & Biomedicine, Neurosciences, Neurosciences & Neurology, Amyloid Precursor Protein, App Locus Duplication, Pluripotent Stem Cells, Pittsburgh Compound B, Positron-Emission-Tomography, Paired Helical Filaments, A-Beta Deposition, Mouse Model, Apolipoprotein-E, Cognitive Decline
UCL classification: UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Neurology
UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Neurology > Molecular Neuroscience
UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Neurology > Neurodegenerative Diseases
URI: http://discovery.ucl.ac.uk/id/eprint/1486595
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