Pratas, AC; Goldschmidt, P; Lebeaux, D; Aguilar, C; Ermak, N; Benesty, J; Charlier, C; ... Errera, MH; + view all Pratas, AC; Goldschmidt, P; Lebeaux, D; Aguilar, C; Ermak, N; Benesty, J; Charlier, C; Benveniste, E; Merabet, L; Sedira, N; Hope-Rapp, E; Chaumeil, C; Bodaghi, B; Héron, E; Sahel, JA; Lortholary, O; Errera, MH; - view fewer (2018) Increase in Ocular Syphilis Cases at Ophthalmologic Reference Center, France, 2012–2015. Emerging Infectious Diseases , 24 (2) pp. 193-200. 10.3201/eid2402.171167.

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Abstract

We describe the frequency, demographic and clinical features, and visual outcomes of ocular syphilis infections observed during 2012–2015 at a tertiary reference center in Paris, France. Twenty-one cases (29 eyes) were identified. The occurrence of ocular syphilis increased from 1 case in 2012 to 5 cases in 2013, 6 cases in 2014, and 9 cases in 2015 (2.22–25.21/1,000 individual patients/year for the period). Among case-patients, an annual 20%–33% were co-infected with HIV. Seventy-six percent of ocular syphilis infections occurred in men who have sex with men. Seventy-five percent of case-patients had a good final visual outcome (best-corrected visual acuity >0.3 logMAR score). Visual outcome was worse for HIV-positive patients than for HIV-negative patients (p = 0.0139). At follow-up, the best visual outcomes were observed in patients whose mean time from first ocular symptom to consultation was 15 days (SD +19 days).

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