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Causation and melanoma classification

Clarke, B; (2011) Causation and melanoma classification. THEORETICAL MEDICINE AND BIOETHICS , 32 (1) 19 - 32. 10.1007/s11017-010-9168-3. Green open access

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In this article, I begin by giving a brief history of melanoma causation. I then discuss the current manner in which malignant melanoma is classified. In general, these systems of classification do not take account of the manner of tumour causation. Instead, they are based on phenomenological features of the tumour, such as size, spread, and morphology. I go on to suggest that misclassification of melanoma is a major problem in clinical practice. I therefore outline an alternative means of classifying these tumours based on causal factors. By analogy with similar systems that have recently emerged for other cancers, I suggest that this causal classification is likely to be both workable and helpful, even in the absence of a full causalmechanistic understanding of the aetiology of the tumour.

Title:Causation and melanoma classification
Open access status:An open access version is available from UCL Discovery
Publisher version:http://dx.doi.org/10.1007/s11017-010-9168-3
Additional information:The final version is available at springerlink.com: http://www.springerlink.com/content/du320105k7033231/. PubMed ID: 21190087
Keywords:Melanoma, Classification, Causation, Mechanism
UCL classification:UCL > School of BEAMS > Faculty of Maths and Physical Sciences > Science and Technology Studies

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