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The role of optical coherence tomography and infrared oculography in assessing the visual pathway and CNS in multiple sclerosis

Coric, D; Nij Bijvank, JA; van Rijn, LJ; Petzold, A; Balk, LJ; (2018) The role of optical coherence tomography and infrared oculography in assessing the visual pathway and CNS in multiple sclerosis. Neurodegenerative Disease Management , 8 (5) pp. 323-335. 10.2217/nmt-2018-0011. Green open access

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Abstract

In this review, a current overview is provided of how optical coherence tomography and infrared oculography can aid in assessing the visual system and CNS in multiple sclerosis (MS). Both afferent and efferent visual disorders are common in MS and visual complaints can have a tremendous impact on daily functioning. Optical coherence tomography and infrared oculography can detect and quantify visual disorders with high accuracy, but could also serve as quantitative markers for inflammation, neurodegeneration and network changes including cognitive decline in MS patients. The assessment of the efferent and afferent visual pathways is relevant for monitoring and predicting the disease course, but is also potentially valuable as an outcome measure in therapeutic trials.

Type: Article
Title: The role of optical coherence tomography and infrared oculography in assessing the visual pathway and CNS in multiple sclerosis
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.2217/nmt-2018-0011
Publisher version: http://dx.doi.org/10.2217/nmt-2018-0011
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: infrared oculography, multiple sclerosis, optical coherence tomography, visual system
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
URI: https://discovery.ucl.ac.uk/id/eprint/10056868
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