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Effect of HIV self-testing on the number of sexual partners among female sex workers in Zambia: A randomized controlled trial

Oldenburg, C; Chanda, MM; Ortblad, KF; Mwale, M; Chongo, S; Kamungoma, N; Kanchele, C; ... Bärnighausen, T; + view all (2018) Effect of HIV self-testing on the number of sexual partners among female sex workers in Zambia: A randomized controlled trial. AIDS , 32 pp. 645-652. 10.1097/QAD.0000000000001740. Green open access

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Abstract

Objectives: To assess the effect of two health system approaches to distribute HIV selftests on the number of female sex workers’ client and nonclient sexual partners. Design: Cluster randomized controlled trial. Methods: Peer educators recruited 965 participants. Peer educator–participant groups were randomized 1 : 1 : 1 to one of three arms: delivery of HIV self-tests directly from a peer educator, free facility-based delivery of HIV self-tests in exchange for coupons, or referral to standard-of-care HIV testing. Participants in all three arms completed four peer educator intervention sessions, which included counseling and condom distribution. Participants were asked the average number of client partners they had per night at baseline, 1 and 4 months, and the number of nonclient partners they had in the past 12 months (at baseline) and in the past month (at 1 month and 4 months). Results: At 4 months, participants reported significantly fewer clients per night in the direct delivery arm (mean difference 0.78 clients, 95% CI 1.28 to 0.28, P ¼ 0.002) and the coupon arm (0.71, 95% CI 1.21 to 0.21, P ¼ 0.005) compared with standard of care. Similarly, they reported fewer nonclient partners in the direct delivery arm (3.19, 95% CI 5.18 to 1.21, P ¼ 0.002) and in the coupon arm (1.84, 95% CI 3.81 to 0.14, P ¼ 0.07) arm compared with standard of care. Conclusion: Expansion of HIV self-testing may have positive behavioral effects enhancing other HIV prevention efforts among female sex workers in Zambia. Trial Registration: ClinicalTrials.gov NCT02827240. Copyright

Type: Article
Title: Effect of HIV self-testing on the number of sexual partners among female sex workers in Zambia: A randomized controlled trial
Open access status: An open access version is available from UCL Discovery
DOI: 10.1097/QAD.0000000000001740
Publisher version: http://doi.org/10.1097/QAD.0000000000001740
Language: English
Additional information: Copyright © 2018 The Author(s). Published by Wolters Kluwer Health, Inc. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: female sex workers, HIV self-testing, sexual behaviors, sub-Saharan Africa
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health
URI: https://discovery.ucl.ac.uk/id/eprint/10045003
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