UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

The risk of cardiac failure following metal-on-metal hip arthroplasty

Sabah, SA; Moon, JC; Jenkins-Jones, S; Morgan, CLI; Currie, CJ; Wilkinson, JM; Porter, M; ... Manisty, C; + view all (2018) The risk of cardiac failure following metal-on-metal hip arthroplasty. Bone & Joint Journal , 100B (1) pp. 20-27. 10.1302/0301-620X.100B1.BJJ-2017-1065.R1. Green open access

[img]
Preview
Text
20.full.pdf - ["content_typename_Published version" not defined]

Download (556kB) | Preview

Abstract

Aims The aim of this study was to determine whether patients with metal-on-metal (MoM) arthroplasties of the hip have an increased risk of cardiac failure compared with those with alternative types of arthroplasties (non-MoM). Patients and Methods A linkage study between the National Joint Registry, Hospital Episodes Statistics and records of the Office for National Statistics on deaths was undertaken. Patients who underwent elective total hip arthroplasty between January 2003 and December 2014 with no past history of cardiac failure were included and stratified as having either a MoM (n = 53 529) or a non-MoM (n = 482 247) arthroplasty. The primary outcome measure was the time to an admission to hospital for cardiac failure or death. Analysis was carried out using data from all patients and from those matched by propensity score. Results The risk of cardiac failure was lower in the MoM cohort compared with the non-MoM cohort (adjusted hazard ratio (aHR) 0.901; 95% confidence interval (CI) 0.853 to 0.953). The risk of cardiac failure was similar following matching (aHR 0.909; 95% CI 0.838 to 0.987) and the findings were consistent in subgroup analysis. Conclusion The risk of cardiac failure following total hip arthroplasty was not increased in those in whom MoM implants were used, compared with those in whom other types of prostheses were used, in the first seven years after surgery.

Type: Article
Title: The risk of cardiac failure following metal-on-metal hip arthroplasty
Open access status: An open access version is available from UCL Discovery
DOI: 10.1302/0301-620X.100B1.BJJ-2017-1065.R1
Publisher version: https://doi.org/10.1302/0301-620X.100B1.BJJ-2017-1...
Language: English
Additional information: This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Keywords: Science & Technology, Life Sciences & Biomedicine, Orthopedics, Surgery, NATIONAL JOINT REGISTRY, RETROSPECTIVE COHORT, COBALT, REPLACEMENT, CARDIOMYOPATHY, EPIDEMIOLOGY, TOXICITY, ENGLAND, SYSTEM, WALES
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Ortho and MSK Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science > Clinical Science
URI: http://discovery.ucl.ac.uk/id/eprint/10043325
Downloads since deposit
62Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item