Gibson, SM;
Macmillan, D;
sheppard, TD;
(2018)
Synthesis of Boronocysteine.
Synlett
, 29
(3)
pp. 314-317.
10.1055/s-0036-1591491.
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Abstract
Herein we report the first synthesis of protected boronocysteine. The target compound was prepared via copper-catalysed diastereoselective nucleophilic borylation of a sulfinimine. After deprotection to give the amine as the hydrochloride salt, four boronocysteine amide derivatives were prepared through reaction with a variety of different active acylating agents.
| Type: | Article |
|---|---|
| Title: | Synthesis of Boronocysteine |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1055/s-0036-1591491 |
| Publisher version: | http://dx.doi.org/10.1055/s-0036-1591491 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | amino acids, boron, copper, imines, peptides |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Chemistry |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10025966 |
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