Browse by UCL people
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Number of items: 34.
Article
Abbosh, Christopher;
Frankell, Alexander M;
Harrison, Thomas;
Kisistok, Judit;
Garnett, Aaron;
Johnson, Laura;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2023)
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Nature
, 616
(7957)
pp. 553-562.
10.1038/s41586-023-05776-4.
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AbdulJabbar, K;
Raza, SEA;
Rosenthal, R;
Jamal-Hanjani, M;
Veeriah, S;
Akarca, A;
Lund, T;
... Yuan, Y; + view all
(2020)
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma.
Nature Medicine
, 26
pp. 1054-1062.
10.1038/s41591-020-0900-x.
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Au, L;
Hatipoglu, E;
Robert de Massy, M;
Litchfield, K;
Beattie, G;
Rowan, A;
Schnidrig, D;
... TRACERx Renal Consortium; + view all
(2021)
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma.
Cancer Cell
, 39
pp. 1497-1518.
10.1016/j.ccell.2021.10.001.
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Bailey, C;
Black, JRM;
Reading, JL;
Litchfield, K;
Turajlic, S;
McGranahan, N;
Jamal-Hanjani, M;
(2021)
Tracking Cancer Evolution through the Disease Course.
Cancer Discovery
, 11
(4)
pp. 916-932.
10.1158/2159-8290.CD-20-1559.
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Barnes, Josephine L;
Yoshida, Masahiro;
He, Peng;
Worlock, Kaylee B;
Lindeboom, Rik GH;
Suo, Chenqu;
Pett, J Patrick;
... Nikolić, Marko Z; + view all
(2023)
Early human lung immune cell development and its role in epithelial cell fate.
Science Immunology
, 8
(90)
, Article eadf9988. 10.1126/sciimmunol.adf9988.
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Bentham, R;
Litchfield, K;
Watkins, TBK;
Lim, EL;
Rosenthal, R;
Martinez-Ruiz, C;
Hiley, CT;
... McGranahan, N; + view all
(2021)
Using DNA sequencing data to quantify T cell fraction and therapy response.
Nature
, 597
pp. 555-560.
10.1038/s41586-021-03894-5.
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Carty, F;
Corbett, JM;
Cunha, JPMCM;
Reading, JL;
Tree, TIM;
Ting, AE;
Stubblefield, SR;
(2018)
Multipotent Adult Progenitor Cells Suppress T Cell Activation in In Vivo Models of Homeostatic Proliferation in a Prostaglandin E2-Dependent Manner.
Frontiers In Immunology
, 9
, Article 645. 10.3389/fimmu.2018.00645.
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Enfield, Katey SS;
Colliver, Emma;
Lee, Claudia SY;
Magness, Alastair;
Moore, David A;
Sivakumar, Monica;
Grigoriadis, Kristiana;
... Angelova, Mihaela; + view all
(2024)
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer.
Cancer Discovery
, 14
(1)
pp. 1-30.
10.1158/2159-8290.CD-23-1380.
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Frankell, Alexander M;
Dietzen, Michelle;
Al Bakir, Maise;
Lim, Emilia L;
Karasaki, Takahiro;
Ward, Sophia;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2024)
The evolution of lung cancer and impact of subclonal selection in TRACERx (vol 616, pg 525, 2023).
[Corrigendum].
Nature
, 631
, Article E15. 10.1038/s41586-024-07738-w.
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Galvez-Cancino, Felipe;
Navarrete, Mariela;
Beattie, Gordon;
Puccio, Simone;
Conde-Gallastegi, Enrique;
Foster, Kane;
Morris, Yasmin;
... Quezada, Sergio A; + view all
(2025)
Correction:
Regulatory T cell depletion promotes myeloid cell activation and glioblastoma response to anti-PD1 and tumor-targeting antibodies.
[Corrigendum].
Immunity
, 58
(7)
pp. 1862-1864.
10.1016/j.immuni.2025.05.019.
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Ghorani, E;
Reading, JL;
Henry, JY;
Massy, MRD;
Rosenthal, R;
Turati, V;
Joshi, K;
... Quezada, SA; + view all
(2020)
The T cell differentiation landscape is shaped by tumour mutations in lung cancer.
Nature Cancer
, 1
(5)
pp. 546-561.
10.1038/s43018-020-0066-y.
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Ghorani, E;
Rosenthal, R;
McGranahan, N;
Reading, JL;
Lynch, M;
Peggs, KS;
Swanton, C;
(2018)
Differential binding affinity of mutated peptides for MHC class I is a predictor of survival in advanced lung cancer and melanoma.
Annals of Oncology
, 29
(1)
pp. 271-279.
10.1093/annonc/mdx687.
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Gómez-López, Sandra;
Alhendi, Ahmed SN;
Przybilla, Moritz J;
Bordeu, Ignacio;
Whiteman, Zoe E;
Butler, Timothy;
Rouhani, Maral J;
... Janes, Sam M; + view all
(2025)
Aberrant basal cell clonal dynamics shape early lung carcinogenesis.
Science
, 388
(6752)
, Article eads9145. 10.1126/science.ads9145.
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Hobor, S;
Al Bakir, M;
Hiley, CT;
Skrzypski, M;
Frankell, AM;
Bakker, B;
Watkins, TBK;
... Clipson, A; + view all
(2024)
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling.
Nature Communications
, 15
, Article 4871. 10.1038/s41467-024-47606-9.
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Holm, Jeppe Sejerø;
Funt, Samuel A;
Borch, Annie;
Munk, Kamilla Kjærgaard;
Bjerregaard, Anne-Mette;
Reading, James L;
Maher, Colleen;
... Hadrup, Sine Reker; + view all
(2022)
Neoantigen-specific CD8 T cell responses in the peripheral blood following PD-L1 blockade might predict therapy outcome in metastatic urothelial carcinoma.
Nature Communications
, 13
, Article 1935. 10.1038/s41467-022-29342-0.
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Hynds, Robert E;
Huebner, Ariana;
Pearce, David R;
Hil, Mark S;
Akarca, Ayse U;
Moore, David A;
Ward, Sophia;
... Swanton, Charles; + view all
(2024)
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models.
Nature Communications
, 15
, Article 4653. 10.1038/s41467-024-47547-3.
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Joshi, K;
Robert de Massy, M;
Ismail, M;
Reading, JL;
Uddin, I;
Woolston, A;
Hatipoglu, E;
... Chain, B; + view all
(2019)
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Nature Medicine
, 25
pp. 1549-1559.
10.1038/s41591-019-0592-2.
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Lebrusant-Fernandez, Marta;
Reading, James L;
(2025)
Beta papillomaviruses: From foe to friend in skin cancer immunity.
Cancer Cell
, 43
(1)
pp. 6-7.
10.1016/j.ccell.2024.12.005.
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Litchfield, K;
Reading, JL;
Lim, EL;
Xu, H;
Liu, P;
Al-Bakir, M;
Wong, YNS;
... Swanton, C; + view all
(2020)
Escape from nonsense-mediated decay associates with anti-tumor immunogenicity.
Nature Communications
, 11
, Article 3800. 10.1038/s41467-020-17526-5.
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Litchfield, K;
Reading, JL;
Puttick, C;
Thakkar, K;
Abbosh, C;
Bentham, R;
Watkins, TBK;
... Swanton, C; + view all
(2021)
Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition.
Cell
, 184
(3)
596-614.e14.
10.1016/j.cell.2021.01.002.
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López, S;
Lim, EL;
Horswell, S;
Haase, K;
Huebner, A;
Dietzen, M;
Mourikis, TP;
... McGranahan, N; + view all
(2020)
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution.
Nature Genetics
, 52
(3)
pp. 283-293.
10.1038/s41588-020-0584-7.
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Puttick, Clare;
Jones, Thomas P;
Leung, Michelle M;
Galvez-Cancino, Felipe;
Liu, Jiali;
Varas-Godoy, Manuel;
Rowan, Andrew;
... Mcgranahan, Nicholas; + view all
(2024)
MHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolution.
Nature Genetics
, 56
(10)
pp. 2121-2131.
10.1038/s41588-024-01883-8.
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Reading, J;
Foster, K;
Joshi, K;
Chain, B;
(2022)
Tracking down tumor-specific T cells.
Cancer Cell
, 40
(4)
pp. 351-353.
10.1016/j.ccell.2022.03.007.
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Reading, James L;
Caswell, Deborah R;
Swanton, Charles;
(2023)
Tumor heterogeneity impairs immunogenicity in mismatch repair deficient tumors.
Nature Genetics
, 55
(10)
pp. 1610-1612.
10.1038/s41588-023-01492-x.
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Reading, JL;
Roobrouck, VD;
Hull, CM;
Becker, PD;
Beyens, J;
Valentin-Torres, A;
Boardman, D;
... Tree, T; + view all
(2021)
Augmented Expansion of Treg Cells From Healthy and Autoimmune Subjects via Adult Progenitor Cell Co-Culture.
Frontiers in Immunology
, 12
, Article 716606. 10.3389/fimmu.2021.716606.
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Reading, JL;
Gálvez-Cancino, F;
Swanton, RC;
Lladser, A;
Peggs, K;
Quezada, S;
(2018)
The function and dysfunction of memory CD8+ T cells in tumor immunity.
Immunological Reviews
, 283
(1)
pp. 194-212.
10.1111/imr.12657.
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Reading, JL;
Quezada, SA;
(2016)
Too Much of a Good Thing? Chronic IFN Fuels Resistance to Cancer Immunotherapy.
Immunity
, 45
(6)
pp. 1181-1183.
10.1016/j.immuni.2016.12.004.
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Rosenthal, R;
Cadieux, EL;
Salgado, R;
Bakir, MA;
Moore, DA;
Hiley, CT;
Lund, T;
... TRACERx consortium; + view all
(2019)
Neoantigen-directed immune escape in lung cancer evolution.
Nature
10.1038/s41586-019-1032-7.
(In press).
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Sabbah, S;
Liew, A;
Brooks, AM;
Kundu, R;
Reading, JL;
Flatt, A;
Counter, C;
... Tree, TIM; + view all
(2020)
Autoreactive T cell profiles are altered following allogeneic islet transplantation with alemtuzumab induction and re‐emerging phenotype is associated with graft function.
American Journal of Transplantation
10.1111/ajt.16285.
(In press).
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Turajlic, S;
Litchfield, K;
Xu, H;
Rosenthal, R;
McGranahan, N;
Reading, JL;
Wong, YNS;
... Swanton, C; + view all
(2017)
Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis.
The Lancet Oncology
, 18
(8)
pp. 1009-1021.
10.1016/S1470-2045(17)30516-8.
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Vargas, FA;
Furness, AJS;
Litchfield, K;
Joshi, K;
Rosenthal, R;
Ghorani, E;
Solomon, I;
... Quezada, SA; + view all
(2018)
Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.
Cancer Cell
, 33
(4)
pp. 649-663.
10.1016/j.ccell.2018.02.010.
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Wong, YNS;
Joshi, K;
Khetrapal, P;
Ismail, M;
Reading, JL;
Sunderland, MW;
Georgiou, A;
... Quezada, SA; + view all
(2018)
Urine-derived lymphocytes as a non-invasive measure of the bladder tumor immune microenvironment.
Journal of Experimental Medicine
, 215
(11)
pp. 2748-2759.
10.1084/jem.20181003.
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Wu, Yin;
Biswas, Dhruva;
Usaite, Ieva;
Angelova, Mihaela;
Boeing, Stefan;
Karasaki, Takahiro;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2022)
A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer.
Nature Cancer
, 3
pp. 696-709.
10.1038/s43018-022-00376-z.
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Yang, JHM;
Cutler, AJ;
Ferreira, RC;
Reading, JL;
Cooper, NJ;
Wallace, C;
Clarke, P;
... Tree, TIM; + view all
(2015)
Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes.
Diabetes
, 64
(11)
pp. 3891-3902.
10.2337/db15-0516.
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