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Number of items: 65.
Article
Adler, AJ;
Casas, JP;
Martin, N;
Free, C;
Perel, P;
(2018)
Cochrane corner: text messaging to improve adherence to drugs for secondary prevention of cardiovascular disease.
Heart
, 104
(22)
pp. 1814-1816.
10.1136/heartjnl-2017-312888.
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Adler, AJ;
Martin, N;
Mariani, J;
Tajer, CD;
Owolabi, OO;
Free, C;
Serrano, NC;
... Perel, P; + view all
(2017)
Mobile phone text messaging to improve medication adherence in secondary prevention of cardiovascular disease.
Cochrane Database of Systematic Reviews
, 2017
(4)
, Article CD011851. 10.1002/14651858.CD011851.pub2.
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Allan, V;
Banerjee, A;
Shah, AD;
Patel, R;
Denaxas, S;
Casas, JP;
Hemingway, H;
(2016)
Net clinical benefit of warfarin in individuals with atrial fibrillation across stroke risk and across primary and secondary care.
Heart
, 103
(3)
pp. 210-218.
10.1136/heartjnl-2016-309910.
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Allan, V;
Honarbakhsh, S;
Casas, J-P;
Wallace, J;
Hunter, R;
Schilling, R;
Perel, P;
... Hemingway, H; + view all
(2017)
Are cardiovascular risk factors also associated with the incidence of atrial fibrillation? A systematic review and field synopsis of 23 factors in 32 population-based cohorts of 20 million participants.
Thrombosis and Haemostasis
, 117
(5)
pp. 837-850.
10.1160/TH16-11-0825.
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Angelakopoulou, A;
Shah, T;
Sofat, R;
Shah, S;
Berry, DJ;
Cooper, J;
Palmen, J;
... Hingorani, AD; + view all
(2012)
Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration.
European Heart Journal
, 33
(3)
393 - 407.
10.1093/eurheartj/ehr225.
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Ariyaratnam, R;
Casas, JP;
Whittaker, J;
Smeeth, L;
Hingorani, AD;
Sharma, P;
(2007)
Genetics of ischaemic stroke among persons of non-European descent: a meta-analysis of eight genes involving approximately 32,500 individuals.
PLoS Medicine
, 4
, Article e131. 10.1371/journal.pmed.0040131.
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Ariyaratnam, R;
Casas, JP;
Whittaker, J;
Smeeth, L;
Hingorani, AD;
Sharma, P;
(2007)
Genetics of ischaemic stroke among persons of non-European descent: A meta-analysis of eight genes involving; 32,500 individuals.
PLoS Medicine
, 4
(4)
, Article e131. 10.1371/journal.pmed.0040131.
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Beaney, KE;
Smith, AJP;
Folkersen, L;
Palmen, J;
Wannamethee, SG;
Jefferis, BJ;
Whincup, P;
... Consortium, U; + view all
(2017)
Functional Analysis of the Coronary Heart Disease Risk Locus on Chromosome 21q22.
Disease Markers
, 2017
, Article 1096916. 10.1155/2017/1096916.
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Bell, S;
Daskalopoulou, M;
Rapsomaniki, E;
George, J;
Britton, A;
Bobak, M;
Casas, JP;
... Hemingway, H; + view all
(2017)
Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: population based cohort study using linked health records.
the BMJ
, 356
, Article j909. 10.1136/bmj.j909.
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Bentham, J;
Di Cesare, M;
Stevens, GA;
Zhou, B;
Bixby, H;
Cowan, M;
Fortunato, L;
... Cisneros, JZ; + view all
(2016)
A century of trends in adult human height.
eLIFE
, 5
, Article e13410. 10.7554/eLife.13410.
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Borges, MC;
Barros, AJD;
Ferreira, DLS;
Casas, JP;
Horta, BL;
Kivimaki, M;
Kumari, M;
... Hingorani, AD; + view all
(2017)
Metabolic Profiling of Adiponectin Levels in Adults: Mendelian Randomization Analysis.
Circulation: Cardiovascular Genetics
, 10
, Article e001837. 10.1161/CIRCGENETICS.117.001837.
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Brunner, EJ;
Kivimaki, M;
Witte, DR;
Lawlor, DA;
Davey Smith, G;
Cooper, JA;
Miller, M;
... Kumari, M; + view all
(2008)
Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream.
PLoS Medicine
, 5
, Article e155. 10.1371/journal.pmed.0050155.
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Brunner, EJ;
Kivimaki, M;
Witte, DR;
Lawlor, DA;
Smith, GD;
Cooper, JA;
Miller, M;
... Kumari, M; + view all
(2008)
Inflammation, insulin resistance, and diabetes-mendelian randomization using CRP haplotypes points upstream.
PLOS MED
, 5
(8)
, Article e155. 10.1371/journal.pmed.0050155.
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Casas, JP;
Hingorani, AD;
(2012)
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.
Lancet
, 379
(9822)
1214 - 1224.
10.1016/S0140-6736(12)60110-X.
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Charoen, P;
Nitsch, D;
Engmann, J;
Shah, T;
White, J;
Zabaneh, D;
Jefferis, B;
... Dudbridge, F; + view all
(2016)
Mendelian Randomisation study of the influence of eGFR on coronary heart disease.
Scientific Reports
, 6
, Article 28514. 10.1038/srep28514.
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Dale, CE;
Fatemifar, G;
Palmer, TM;
White, J;
Prieto-Merino, D;
Zabaneh, D;
Engmann, JEL;
... Casas, JP; + view all
(2017)
Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis.
Circulation
, 135
(24)
pp. 2373-2388.
10.1161/CIRCULATIONAHA.116.026560.
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Di Cesare, M;
Bentham, J;
Stevens, GA;
Zhou, B;
Danaei, G;
Lu, Y;
Bixby, H;
... NCD, NRFC; + view all
(2016)
Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19.2 million participants.
The Lancet
, 387
(10026)
pp. 1377-1396.
10.1016/S0140-6736(16)30054-X.
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Drenos, F;
Smith, GD;
Ala-Korpela, M;
Kettunen, J;
Wurtz, P;
Soininen, P;
Kangas, AJ;
... Timpson, NJ; + view all
(2016)
Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase-Independent Effects.
Circulation: Cardiovascular Genetics
, 9
(3)
pp. 231-239.
10.1161/CIRCGENETICS.115.001302.
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Ebrahim, S;
Pearce, N;
Smeeth, L;
Casas, JP;
Jaffar, S;
Piot, P;
(2013)
Tackling non-communicable diseases in low- and middle-income countries: is the evidence from high-income countries all we need?
PLoS Medicine
, 10
(1)
, Article e1001377. 10.1371/journal.pmed.1001377.
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Fairoozy, RH;
Cooper, J;
White, J;
Giambartolomei, C;
Folkersen, L;
Wannamethee, SG;
Jefferis, BJ;
... UCLEB consortium, .; + view all
(2017)
Identifying low density lipoprotein cholesterol associated variants in the Annexin A2 (ANXA2) gene.
Atherosclerosis
, 261
pp. 60-68.
10.1016/j.atherosclerosis.2017.04.010.
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Finan, C;
Gaulton, A;
Kruger, FA;
Lumbers, RT;
Shah, T;
Engmann, J;
Galver, L;
... Casas, JP; + view all
(2017)
The druggable genome and support for target identification and validation in drug development.
Science Translational Medicine
, 9
(383)
, Article eaag1166. 10.1126/scitranslmed.aag1166.
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Harrison, SC;
Smith, AJ;
Jones, GT;
Swerdlow, DI;
Rampuri, R;
Bown, MJ;
Aneurysm Consortium;
... Humphries, SE; + view all
(2013)
Interleukin-6 receptor pathways in abdominal aortic aneurysm.
European Heart Journal
, 34
(48)
, Article ehs354v1. 10.1093/eurheartj/ehs354.
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Hawkesworth, S;
Silverwood, RJ;
Armstrong, B;
Pliakas, T;
Nanchahal, K;
Sartini, C;
Amuzu, A;
... Lock, K; + view all
(2017)
Investigating the importance of the local food environment for fruit and vegetable intake in older men and women in 20 UK towns: a cross-sectional analysis of two national cohorts using novel methods.
International Journal of Behavioral Nutrition and Physical Activity
, 14
, Article 128. 10.1186/s12966-017-0581-0.
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Hawkesworth, S;
Silverwood, RJ;
Armstrong, B;
Pliakas, T;
Nanchalal, K;
Jefferis, BJ;
Sartini, C;
... Lock, K; + view all
(2018)
Investigating associations between the built environment and physical activity among older people in 20 UK towns.
J Epidemiol Community Health
, 72
(2)
pp. 121-131.
10.1136/jech-2017-209440.
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Holmes, MV;
Asselbergs, FW;
Palmer, TM;
Drenos, F;
Lanktree, MB;
Nelson, CP;
Dale, CE;
... Casas, JP; + view all
(2015)
Mendelian randomization of blood lipids for coronary heart disease.
Eur Heart J
, 36
(9)
539 - 550.
10.1093/eurheartj/eht571.
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Holmes, MV;
Dale, CE;
Zuccolo, L;
Silverwood, RJ;
Guo, Y;
Ye, Z;
Prieto-Merino, D;
... InterAct Consortium; + view all
(2014)
Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.
BMJ
, 349
, Article g4164. 10.1136/bmj.g4164.
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Holmes, MV;
Shah, T;
Vickery, C;
Smeeth, L;
Hingorani, AD;
Casas, JP;
(2009)
Fulfilling the Promise of Personalized Medicine? Systematic Review and Field Synopsis of Pharmacogenetic Studies.
PLOS ONE
, 4
(12)
, Article e7960. 10.1371/journal.pone.0007960.
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Jefferis, BJ;
Sartini, C;
Lee, IM;
Choi, M;
Amuzu, A;
Gutierrez, C;
Casas, JP;
... Whincup, PH; + view all
(2014)
Adherence to physical activity guidelines in older adults, using objectively measured physical activity in a population-based study.
BMC Public Health
, 14
p. 382.
10.1186/1471-2458-14-382.
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Kivimaki, M;
Lawlor, DA;
Smith, GD;
Kumari, M;
Donald, A;
Britton, A;
Casas, JP;
... Hingorani, AD; + view all
(2008)
Does high C-reactive protein concentration increase atherosclerosis? The Whitehall II Study.
PLoS One
, 3
(8)
, Article e3013. 10.1371/journal.pone.0003013.
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Kivimaki, M;
Lawlor, DA;
Smith, GD;
Kumari, M;
Donald, A;
Britton, A;
Casas, JP;
... Hingorani, AD; + view all
(2008)
Does High C-reactive Protein Concentration Increase Atherosclerosis? The Whitehall II Study.
PLOS ONE
, 3
(8)
, Article e3013. 10.1371/journal.pone.0003013.
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Kumari, M;
Holmes, MV;
Dale, CE;
Hubacek, J;
Palmer, TM;
Pikhart, H;
Peasey, A;
... Bobak, M; + view all
(2014)
Alcohol Consumption and Cognitive Performance: a Mendelian Randomisation Study.
Addiction
, 109
(9)
1462- 1471.
10.1111/add.12568.
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Lumbers, RT;
Martin, N;
Manoharan, K;
Nyong, J;
Thomas, J;
Casas, JP;
Davies, C;
(2017)
Beta-blockers and inhibitors of the renin-angiotensin aldosterone system for chronic heart failure with preserved ejection fraction.
Cochrane Database of Systematic Reviews
, 2017
(7)
, Article CD012721. 10.1002/14651858.CD012721.
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McGinnis, R;
Steinthorsdottir, V;
Williams, NO;
Thorleifsson, G;
Shooter, S;
Hjartardottir, S;
Bumpstead, S;
... Morgan, L; + view all
(2017)
Variants in the fetal genome near FLT1 are associated with risk of preeclampsia.
Nature Genetics
, 49
(8)
pp. 1255-1260.
10.1038/ng.3895.
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McLachlan, S;
Giambartolomei, C;
White, J;
Charoen, P;
Wong, A;
Finan, C;
Engmann, J;
... UCLEB Consortium; + view all
(2016)
Replication and Characterization of Association between ABO SNPs and Red Blood Cell Traits by Meta-Analysis in Europeans.
PLoS One
, 11
(6)
, Article e0156914. 10.1371/journal.pone.0156914.
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Miranda, JJ;
Herrera, VM;
Chirinos, JA;
Gómez, LF;
Perel, P;
Pichardo, R;
González, A;
... Bautista, LE; + view all
(2013)
Major Cardiovascular Risk Factors in Latin America: A Comparison with the United States. The Latin American Consortium of Studies in Obesity (LASO).
PLoS One
, 8
(1)
, Article e54056. 10.1371/journal.pone.0054056.
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Morris, RW;
Cooper, JA;
Shah, T;
Wong, A;
Drenos, F;
Engmann, J;
McLachlan, S;
... UCLEB Consortium, .; + view all
(2016)
Marginal role for 53 common genetic variants in cardiovascular disease prediction.
Heart
10.1136/heartjnl-2016-309298.
(In press).
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Munafò, MR;
Timofeeva, MN;
Morris, RW;
Prieto-Merino, D;
Sattar, N;
Brennan, P;
Johnstone, EC;
... Davey Smith, G; + view all
(2012)
Association Between Genetic Variants on Chromosome 15q25 Locus and Objective Measures of Tobacco Exposure.
Journal of the National Cancer Institute
, 104
(10)
740 - 748.
10.1093/jnci/djs191.
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NCD Risk Factor Collaboration (NCD-RisC), .;
Bentham, J;
Di Cesare, M;
Bilano, V;
Bixby, H;
Zhou, B;
Stevens, GA;
... Ezzati, M; + view all
(2017)
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults.
The Lancet
, 390
(10113)
pp. 2627-2642.
10.1016/S0140-6736(17)32129-3.
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Nüesch, E;
Dale, C;
Palmer, TM;
White, J;
Keating, BJ;
Van Iperen, EP;
Goel, A;
... Casas, JP; + view all
(2016)
Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis.
International Journal of Epidemiology
, 45
(6)
pp. 1927-1937.
10.1093/ije/dyv074.
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Nyong, J;
Amit, G;
Adler, AJ;
Owolabi, OO;
Perel, P;
Prieto-Merino, D;
Lambiase, P;
... Morillo, CA; + view all
(2016)
Efficacy and safety of ablation for people with non-paroxysmal atrial fibrillation.
Cochrane Database Syst Rev
, 2016
(11)
, Article CD012088. 10.1002/14651858.CD012088.pub2.
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Peck, G;
Smeeth, L;
Whittaker, J;
Casas, JP;
Hingorani, A;
Sharma, P;
(2008)
The Genetics of Primary Haemorrhagic Stroke, Subarachnoid Haemorrhage and Ruptured Intracranial Aneurysms in Adults.
PLOS ONE
, 3
(11)
, Article e3691. 10.1371/journal.pone.0003691.
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Perel, P;
Casas, JP;
Ortiz, Z;
Miranda, JJ;
(2006)
Noncommunicable diseases and injuries in Latin America and the Caribbean: Time for action.
PLoS Medicine
, 3
(9)
, Article e344. 10.1371/journal.pmed.0030344.
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Perel, P;
Miranda, JJ;
Ortiz, Z;
Casas, JP;
(2008)
Relation between the Global Burden of Disease and Randomized Clinical Trials Conducted in Latin America Published in the Five Leading Medical Journals.
PLOS ONE
, 3
(2)
, Article e1696. 10.1371/journal.pone.0001696.
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Pliakas, T;
Hawkesworth, S;
Silverwood, RJ;
Nanchahal, K;
Grundy, C;
Armstrong, B;
Casas, JP;
... Lock, K; + view all
(2017)
Optimising measurement of health-related characteristics of the built environment: Comparing data collected by foot-based street audits, virtual street audits and routine secondary data sources.
Health & Place
, 43
pp. 75-84.
10.1016/j.healthplace.2016.10.001.
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Psychosis Endophenotypes International Consortium, .;
Wellcome Trust Case-Control Consortium 2, .;
Bramon, E;
Pirinen, M;
Strange, A;
Lin, K;
Freeman, C;
... Spencer, CC; + view all
(2014)
A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation.
Biological Psychiatry
, 75
(5)
386 - 397.
10.1016/j.biopsych.2013.03.033.
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Roach, AN;
Braithwaite, T;
Carrington, C;
Marcellin, E;
Sharma, S;
Hingorani, A;
Casas, JP;
... Bourne, R; + view all
(2016)
Addressing ethical challenges in the Genetics Substudy of the National Eye Survey of Trinidad and Tobago (GSNESTT).
Applied & Translational Genomics
, 9
pp. 6-14.
10.1016/j.atg.2016.05.001.
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Sánchez-Santos, MT;
Mesa-Frias, M;
Choi, M;
Nüesch, E;
Asunsolo-Del Barco, A;
Amuzu, A;
Smith, GD;
... Casas, JP; + view all
(2013)
Area-Level Deprivation and Overall and Cause-Specific Mortality: 12 Years' Observation on British Women and Systematic Review of Prospective Studies.
PLoS One
, 8
(9)
, Article e72656. 10.1371/journal.pone.0072656.
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Schmidt, AF;
Pearce, LS;
Wilkins, JT;
Casas, JP;
Hingorani, AD;
(2018)
Cochrane corner: PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease.
[Editorial comment].
Heart
, 104
(13)
pp. 1053-1055.
10.1136/heartjnl-2017-312858.
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Schmidt, AF;
Pearce, LS;
Wilkins, JT;
Overington, JP;
Hingorani, AD;
Casas, JP;
(2017)
PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(4)
10.1002/14651858.CD011748.pub2.
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Schmidt, AF;
Swerdlow, DI;
Holmes, MV;
Patel, RS;
Fairhurst-Hunter, Z;
Lyall, DM;
Hartwig, FP;
... Sattar, N; + view all
(2017)
PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.
The Lancet: Diabetes and Endocrinology
, 5
(2)
pp. 97-105.
10.1016/S2213-8587(16)30396-5.
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Serrano, NC;
Diaz, LA;
Paez, MC;
Mesa, CM;
Cifuentes, R;
Monterrosa, A;
Gonzalez, A;
... Casas, JP; + view all
(2006)
Angiotensin-converting enzyme I/D polymorphism and preeclampsia risk: evidence of small-study bias.
PLoS Medicine
, 3
, Article e520. 10.1371/journal.pmed.0030520.
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Serrano, NC;
Diaz, LA;
Paez, MC;
Mesa, CM;
Cifuentes, R;
Monterrosa, A;
Gonzalez, A;
... Casas, JP; + view all
(2006)
Angiotensin-converting enzyme I/D polymorphism and preeclampsia risk: Evidence of small-study bias.
PLoS Medicine
, 3
(12)
, Article e520. 10.1371/journal.pmed.0030520.
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Serrano, NC;
Guio-Mahecha, E;
Cristina Quintero-Lesmes, D;
Becerra-Bayona, S;
Paez, MC;
Beltran, M;
Herrera, VM;
... Casas, JP; + view all
(2018)
Lipid profile, plasma apolipoproteins, and pre-eclampsia risk in the GenPE case-control study.
Atherosclerosis
, 276
pp. 189-194.
10.1016/j.atherosclerosis.2018.05.051.
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Shah, T;
Engmann, J;
Dale, C;
Shah, S;
White, J;
Giambartolomei, C;
McLachlan, S;
... UCLEB Consortium; + view all
(2013)
Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium.
PLoS One
, 8
(8)
, Article e71345. 10.1371/journal.pone.0071345.
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Sofat, R;
Cooper, JA;
Kumari, M;
Casas, JP;
Mitchell, JP;
Acharya, J;
Thom, S;
... Hingorani, AD; + view all
(2016)
Circulating Apolipoprotein E Concentration and Cardiovascular Disease Risk: Meta-analysis of Results from Three Studies.
PLoS Medicine
, 13
(10)
, Article e1002146. 10.1371/journal.pmed.1002146.
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Swerdlow, DI;
Kuchenbaecker, KB;
Shah, S;
Sofat, R;
Holmes, MV;
White, J;
Mindell, JS;
... Hingorani, AD; + view all
(2016)
Selecting instruments for Mendelian randomization in the wake of genome-wide association studies.
International Journal of Epidemiology
, 45
(5)
pp. 1600-1616.
10.1093/ije/dyw088.
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Taylor, AE;
Fluharty, ME;
Bjørngaard, JH;
Gabrielsen, ME;
Skorpen, F;
Marioni, RE;
Campbell, A;
... Munafò, MR; + view all
(2014)
Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium.
BMJ Open
, 4
(10)
, Article e006141. 10.1136/bmjopen-2014-006141.
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White, J;
Sofat, R;
Hemani, G;
Shah, T;
(2016)
Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis.
The Lancet Diabetes and Endocrinology
, 4
(4)
pp. 327-336.
10.1016/S2213-8587(15)00386-1.
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Willeit, P;
Kaptoge, S;
Welsh, P;
Butterworth, AS;
Chowdhury, R;
Spackman, SA;
Pennells, L;
... Di Angelantonio, E; + view all
(2016)
Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis.
The Lancet Diabetes & Endocrinology
, 4
(10)
pp. 840-849.
10.1016/S2213-8587(16)30196-6.
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Wurtz, P;
Havulinna, AS;
Soininen, P;
Tynkkynen, T;
Prieto-Merino, D;
Tillin, T;
Ghorbani, A;
... Salomaa, V; + view all
(2015)
Metabolite Profiling and Cardiovascular Event Risk: A Prospective Study of 3 Population-Based Cohorts.
Circulation
, 131
(9)
pp. 774-785.
10.1161/CIRCULATIONAHA.114.013116.
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Würtz, P;
Wang, Q;
Soininen, P;
Kangas, AJ;
Fatemifar, G;
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