Browse by UCL people
Group by: Type | Date
Number of items: 61.
Article
Barnes, J;
Carmichael, OT;
Leung, KK;
Schwarz, C;
Ridgway, GR;
Bartlett, JW;
Malone, IB;
... Alzheimer's Disease Neuroimaging Initiative, The; + view all
(2013)
Vascular and Alzheimer's disease markers independently predict brain atrophy rate in Alzheimer's Disease Neuroimaging Initiative controls.
Neurobiology of Aging
, 34
(8)
1996 - 2002.
10.1016/j.neurobiolaging.2013.02.003.
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Bocchetta, Martina;
Todd, Emily G;
Bouzigues, Arabella;
Cash, David M;
Nicholas, Jennifer M;
Convery, Rhian S;
Russell, Lucy L;
... Afonso, Sónia; + view all
(2023)
Structural MRI predicts clinical progression in presymptomatic genetic frontotemporal dementia: findings from the GENetic Frontotemporal dementia Initiative (GENFI) cohort.
Brain Communications
10.1093/braincomms/fcad061.
(In press).
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Brown, Thomas M;
James, Sarah-Naomi;
Nicholas, Jennifer M;
Keuss, Sarah;
Keshavan, Ashvini;
Malone, Ian B;
Coath, William;
... Barnes, Josephine; + view all
(2025)
Association of Increase in White Matter Hyperintensity Volume With Rate of Hippocampal Atrophy in a Population-Based Study of Aging.
Neurology
, 105
(5)
, Article e213975. 10.1212/WNL.0000000000213975.
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Buchanan, SM;
Parker, TD;
Lane, CA;
Keshavan, A;
Keuss, SE;
Lu, K;
James, S-N;
... Schott, JM; + view all
(2020)
Olfactory testing does not predict beta-amyloid, MRI measures of neurodegeneration or vascular pathology in the British 1946 birth cohort.
Journal of Neurology
10.1007/s00415-020-10004-4.
(In press).
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Cash, DM;
Frost, C;
Iheme, LO;
Ünay, D;
Kandemir, M;
Fripp, J;
Salvado, O;
... Ourselin, S; + view all
(2015)
Assessing atrophy measurement techniques in dementia: Results from the MIRIAD atrophy challenge.
Neuroimage
, 123
pp. 149-164.
10.1016/j.neuroimage.2015.07.087.
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Cash, DM;
Ridgway, GR;
Liang, Y;
Ryan, NS;
Kinnunen, KM;
Yeatman, T;
Malone, IB;
... On behalf of the Dominantly Inherited Alzheimer Network (DIAN), .; + view all
(2013)
The pattern of atrophy in familial Alzheimer disease: Volumetric MRI results from the DIAN study.
Neurology
, 81
(16)
pp. 1425-1433.
10.1212/WNL.0b013e3182a841c6.
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Chen, S-D;
Lu, J-Y;
Li, H-Q;
Yang, Y-X;
Jiang, J-H;
Cui, M;
Zuo, C-T;
... Alzheimer’s Disease Neuroimaging Initiative; + view all
(2021)
Staging tau pathology with tau PET in Alzheimer's disease: a longitudinal study.
Translational Psychiatry
, 11
, Article 483. 10.1038/s41398-021-01602-5.
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Coath, William;
Modat, Marc;
Cardoso, M Jorge;
Markiewicz, Pawel J;
Lane, Christopher A;
Parker, Thomas D;
Keshavan, Ashvini;
... Alzheimer's Disease Neuroimaging Initiative; + view all
(2023)
Operationalizing the centiloid scale for [18F]florbetapir PET studies on PET/MRI.
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
, 15
(2)
, Article e12434. 10.1002/dad2.12434.
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Fatih, N;
Chaturvedi, N;
Lane, CA;
Parker, TD;
Lu, K;
Cash, DM;
Malone, IB;
... James, S-N; + view all
(2022)
Sex-related differences in whole brain volumes at age 70 in association with hyperglycemia during adult life.
Neurobiology of Aging
, 112
pp. 161-169.
10.1016/j.neurobiolaging.2021.09.008.
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Fiford, CM;
Sudre, CH;
Young, AL;
Macdougall, A;
Nicholas, J;
Manning, EN;
Malone, IB;
... Alzheimer’s Disease Neuroimaging Initiative, .; + view all
(2021)
Presumed small vessel disease, imaging and cognition markers in the Alzheimer's Disease Neuroimaging Initiative.
Brain Communications
, 3
(4)
, Article fcab226. 10.1093/braincomms/fcab226.
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Fiford, C;
Sudre, C;
Pemberton, H;
Walsh, P;
Manning, E;
Malone, I;
Nicholas, J;
... Barnes, J; + view all
(2020)
Automated white matter hyperintensity segmentation using Bayesian Model Selection: assessment and correlations with cognitive change.
NeuroInformatics
10.1007/s12021-019-09439-6.
(In press).
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Fiford, CM;
Manning, EN;
Bartlett, JW;
Cash, DM;
Malone, IB;
Ridgway, GR;
Lehmann, M;
... Alzheimer's Disease Neuroimaging Initiative; + view all
(2017)
White matter hyperintensities are associated with disproportionate progressive hippocampal atrophy.
Hippocampus
, 27
(3)
pp. 249-262.
10.1002/hipo.22690.
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Fiford, CM;
Ridgway, GR;
Cash, DM;
Modat, M;
Nicholas, J;
Manning, EN;
Malone, IB;
... Alzheimer's Disease Neuroimaging Initiative, .; + view all
(2018)
Patterns of progressive atrophy vary with age in Alzheimer's disease patients.
Neurobiology of Aging
, 63
pp. 22-32.
10.1016/j.neurobiolaging.2017.11.002.
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Green, Rebecca E;
Lord, Jodie;
Scelsi, Marzia A;
Xu, Jin;
Wong, Andrew;
Naomi-James, Sarah;
Handy, Alex;
... Insight 46 study team; + view all
(2023)
Investigating associations between blood metabolites, later life brain imaging measures, and genetic risk for Alzheimer’s disease.
Alzheimer's Research and Therapy
, 15
, Article 38. 10.1186/s13195-023-01184-y.
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Harris, MJ;
Lane, CA;
Coath, W;
Malone, IB;
Cash, DM;
Barnes, J;
Barkhof, F;
(2022)
Familial British dementia: a clinical and multi-modal imaging case study.
Journal of Neurology
, 269
pp. 3926-3930.
10.1007/s00415-022-11036-8.
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He, Qiling;
Shi, Lin;
Luo, Yishan;
Wan, Chao;
Malone, Ian B;
Mok, Vincent CT;
Cole, James H;
(2022)
Validation of the Alzheimer's disease-resemblance atrophy index in classifying and predicting progression in Alzheimer's disease.
Frontiers in Aging Neuroscience
, 14
, Article 932125. 10.3389/fnagi.2022.932125.
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Hobbs, NZ;
Farmer, RE;
Rees, EM;
Cole, JH;
Haider, S;
Malone, IB;
Sprengelmeyer, R;
... Tabrizi, SJ; + view all
(2015)
Short-interval observational data to inform clinical trial design in Huntington's disease.
Journal of Neurology, Neurosurgery and Psychiatry
10.1136/jnnp-2014-309768.
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James, Sarah-Naomi;
Manning, Emily N;
Storey, Mathew;
Nicholas, Jennifer M;
Coath, William;
Keuss, Sarah E;
Cash, David M;
... Schott, Jonathan M; + view all
(2023)
Neuroimaging, clinical and life course correlates of normal-appearing white matter integrity in 70-year-olds.
Brain Communications
, Article fcad225. 10.1093/braincomms/fcad225.
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James, S-N;
Nicholas, JM;
Lane, CA;
Parker, TD;
Lu, K;
Keshavan, A;
Buchanan, SM;
... Fox, NC; + view all
(2021)
A population‐based study of head injury, cognitive function and pathological markers.
Annals of Clinical and Translational Neurology
10.1002/acn3.51331.
(In press).
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Johnson, EB;
Rees, EM;
Labuschagne, I;
Durr, A;
Leavitt, BR;
Roos, RA;
Reilmann, R;
... Scahill, RI; + view all
(2015)
The impact of occipital lobe cortical thickness on cognitive task performance: An investigation in Huntington's Disease.
Neuropsychologia
, 79
(Pt A)
pp. 138-146.
10.1016/j.neuropsychologia.2015.10.033.
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Kehoe, PG;
Turner, N;
Howden, B;
Jarutyt, L;
Clegg, SL;
Malone, IB;
Barnes, J;
... Ben-Shlomo, Y; + view all
(2021)
Losartan to slow the progression of mild-to-moderate Alzheimer's disease through angiotensin targeting: the RADAR RCT.
Efficacy and Mechanism Evaluation
, 8
(19)
pp. 1-72.
10.3310/eme08190.
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Kehoe, PG;
Turner, N;
Howden, B;
Jarutyte, L;
Clegg, SL;
Malone, IB;
Barnes, J;
... RADAR investigators, .; + view all
(2021)
Safety and efficacy of losartan for the reduction of brain atrophy in clinically diagnosed Alzheimer's disease (the RADAR trial): a double-blind, randomised, placebo-controlled, phase 2 trial.
Lancet Neurology
, 20
(11)
pp. 895-906.
10.1016/S1474-4422(21)00263-5.
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Kehoe, PG;
Blair, PS;
Howden, B;
Thomas, DL;
Malone, IB;
Horwood, J;
Clement, C;
... Ben-Shlomo, Y; + view all
(2017)
The Rationale and Design of the Reducing Pathology in Alzheimer's Disease through Angiotensin TaRgeting (RADAR) Trial.
Journal of Alzheimer's Disease
, 61
(2)
pp. 803-814.
10.3233/JAD-170101.
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Keihaninejad, S;
Ryan, NS;
Malone, IB;
Modat, M;
Cash, D;
Ridgway, GR;
Zhang, H;
... Ourselin, S; + view all
(2012)
The importance of group-wise registration in tract based spatial statistics study of neurodegeneration: a simulation study in Alzheimer's disease.
PLOS One
, 7
(11)
, Article e45996. 10.1371/journal.pone.0045996.
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Keuss, Sarah E;
Coath, William;
Cash, David M;
Barnes, Josephine;
Nicholas, Jennifer M;
Lane, Christopher A;
Parker, Thomas D;
... Schott, Jonathan M; + view all
(2024)
Rates of cortical thinning in Alzheimer's disease signature regions associate with vascular burden but not with β-amyloid status in cognitively normal adults at age 70.
Journal of Neurology, Neurosurgery, and Psychiatry
10.1136/jnnp-2023-332067.
(In press).
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Keuss, Sarah E;
Coath, William;
Nicholas, Jennifer M;
Poole, Teresa;
Barnes, Josephine;
Cash, David M;
Lane, Christopher A;
... Schott, Jonathan M; + view all
(2022)
Associations of β-Amyloid and Vascular Burden With Rates of Neurodegeneration in Cognitively Normal Members of the 1946 British Birth Cohort.
Neurology
10.1212/WNL.0000000000200524.
(In press).
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Keuss, SE;
Parker, TD;
Lane, CA;
Hoskote, C;
Shah, S;
Cash, DM;
Keshavan, A;
... Schott, JM; + view all
(2019)
Incidental findings on brain imaging and blood tests: results from the first phase of Insight 46, a prospective observational substudy of the 1946 British birth cohort.
BMJ Open
, 9
(7)
, Article e029502. 10.1136/bmjopen-2019-029502.
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Kinnunen, KM;
Cash, DM;
Poole, T;
Frost, C;
Benzinger, TLS;
Ahsan, RL;
Leung, KK;
... Dominantly Inherited Alzheimer Network (DIAN), .; + view all
(2017)
Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial MRI study.
Alzheimer's & Dementia
, 14
(1)
pp. 43-53.
10.1016/j.jalz.2017.06.2268.
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Lane, CA;
Barnes, J;
Nicholas, JM;
Baker, JW;
Sudre, CH;
Cash, DM;
Parker, TD;
... Schott, JM; + view all
(2021)
Investigating the relationship between BMI across adulthood and late life brain pathologies.
Alzheimer's Research and Therapy
, 13
(1)
, Article 91. 10.1186/s13195-021-00830-7.
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Lane, CA;
Barnes, J;
Nicholas, JM;
Sudre, CH;
Cash, DM;
Malone, IB;
Parker, TD;
... Schott, JM; + view all
(2019)
Associations Between Vascular Risk Across Adulthood and Brain Pathology in Late Life: Evidence From a British Birth Cohort.
JAMA Neurology
, 77
(2)
pp. 175-183.
10.1001/jamaneurol.2019.3774.
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Lane, CA;
Barnes, J;
Nicholas, JM;
Sudre, CH;
Cash, DM;
Parker, TD;
Malone, IB;
... Schott, JM; + view all
(2019)
Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study.
Lancet Neurology
10.1016/S1474-4422(19)30228-5.
(In press).
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Lane, CA;
Parker, TD;
Cash, DM;
Macpherson, K;
Donnachie, E;
Murray-Smith, H;
Barnes, A;
... Schott, JM; + view all
(2017)
Study protocol: Insight 46 - a neuroscience sub-study of the MRC National Survey of Health and Development.
BMC Neurology
, 17
, Article 75. 10.1186/s12883-017-0846-x.
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Lu, K;
Nicholas, JM;
Pertzov, Y;
Grogan, J;
Husain, M;
Pavisic, IM;
James, S-N;
... Crutch, SJ; + view all
(2021)
Dissociable effects of APOE ε4 and β-amyloid pathology on visual working memory.
Nature Aging
, 1
pp. 1002-1009.
10.1038/s43587-021-00117-4.
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Lu, K;
Nicholas, JM;
Collins, JD;
James, S-N;
Parker, TD;
Lane, CA;
Keshavan, A;
... Schott, JM; + view all
(2019)
Cognition at age 70: Life course predictors and associations with brain pathologies.
Neurology
, 93
10.1212/WNL.0000000000008534.
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Lu, K;
Nicholas, JM;
James, S;
Lane, CA;
Parker, TD;
Keshavan, A;
Keuss, SE;
... Crutch, SJ; + view all
(2020)
Increased variability in reaction time is associated with amyloid beta pathology at age 70.
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
, 12
(1)
, Article e12076. 10.1002/dad2.12076.
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Lu, K;
Nicholas, JM;
Weston, PSJ;
Stout, JC;
O’Regan, AM;
James, SN;
Buchanan, SM;
... Crutch, SJ; + view all
(2021)
Visuomotor integration deficits are common to familial and sporadic preclinical Alzheimer's disease.
Brain Communications
, 3
(1)
, Article fcab003. 10.1093/braincomms/fcab003.
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Mahoney, CJ;
Ridgway, GR;
Malone, IB;
Downey, LE;
Beck, J;
Kinnunen, KM;
Schmitz, N;
... Warren, JD; + view all
(2014)
Profiles of white matter tract pathology in frontotemporal dementia.
Hum Brain Mapp
, 35
(8)
pp. 4163-4179.
10.1002/hbm.22468.
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Malone, I;
Leung, KL;
Clegg, S;
Barnes, J;
Whitwell, JL;
Ashburner, J;
Fox, NC;
(2015)
Accurate automatic estimation of total intracranial volume: a nuisance variable with less nuisance.
Neuroimage
, 104
10.1016/j.neuroimage.2014.09.034.
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Malone, IB;
Cash, D;
Ridgway, GR;
MacManus, DG;
Ourselin, S;
Fox, NC;
Schott, JM;
(2013)
MIRIAD--Public release of a multiple time point Alzheimer's MR imaging dataset.
Neuroimage
, 70
33 - 36.
10.1016/j.neuroimage.2012.12.044.
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Manning, EN;
Leung, KK;
Nicholas, JM;
Malone, IB;
Cardoso, MJ;
Schott, JM;
Fox, NC;
(2017)
A Comparison of Accelerated and Non-accelerated MRI Scans for Brain Volume and Boundary Shift Integral Measures of Volume Change: Evidence from the ADNI Dataset.
NEUROINFORMATICS
, 15
(2)
pp. 215-226.
10.1007/s12021-017-9326-0.
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Mansoor, NM;
Vanniyasingam, T;
Malone, I;
Hobbs, NZ;
Rees, E;
Durr, A;
Roos, RAC;
... Scahill, RI; + view all
(2021)
Validating Automated Segmentation Tools in the Assessment of Caudate Atrophy in Huntington’s Disease.
Frontiers in Neurology
, 12
, Article 616272. 10.3389/fneur.2021.616272.
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Moss, DJH;
Pardinas, AF;
Langbehn, D;
Lo, K;
Leavitt, BR;
Roos, R;
Durr, A;
... Tabrizi, SJ; + view all
(2017)
Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study.
Lancet Neurology
, 16
(9)
pp. 701-711.
10.1016/S1474-4422(17)30161-8.
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Murray-Smith, H;
Barker, S;
Barkhof, F;
Barnes, J;
Brown, TM;
Captur, G;
R.E.Cartlidge, M;
... Schott, JM; + view all
(2024)
Updating the study protocol: Insight 46 – a longitudinal neuroscience sub-study of the MRC National Survey of Health and Development – phases 2 and 3.
BMC Neurology
, 24
, Article 40. 10.1186/s12883-023-03465-3.
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O’Connor, A;
Cash, DM;
Poole, T;
Markiewicz, PJ;
Fraser, MR;
Malone, IB;
Jiao, J;
... Fox, NC; + view all
(2023)
Tau accumulation in autosomal dominant Alzheimer’s disease: a longitudinal [18F]flortaucipir study.
Alzheimer's Research and Therapy
, 15
, Article 99. 10.1186/s13195-023-01234-5.
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Parker, CS;
Veale, T;
Bocchetta, M;
Slattery, CF;
Malone, IB;
Thomas, DL;
Schott, JM;
... Zhang, H; + view all
(2021)
Not all voxels are created equal: reducing estimation bias in regional NODDI metrics using tissue-weighted means.
NeuroImage
, Article 118749. 10.1016/j.neuroimage.2021.118749.
(In press).
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Parker, T;
Cash, DM;
Lane, C;
Lu, K;
Malone, IB;
Nicholas, JM;
James, S;
... Schott, JM; + view all
(2020)
Pure tone audiometry and cerebral pathology in healthy older adults.
Journal of Neurology, Neurosurgery & Psychiatry
, 91
(2)
pp. 172-176.
10.1136/jnnp-2019-321897.
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Parker, TD;
Cash, DM;
Lane, CA;
Lu, K;
Malone, IB;
Nicholas, JM;
James, S;
... Schott, JM; + view all
(2020)
Amyloid β influences the relationship between cortical thickness and vascular load.
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
, 12
(1)
, Article e12022. 10.1002/dad2.12022.
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Parker, TD;
Cash, DM;
Lane, CAS;
Lu, K;
Malone, IB;
Nicholas, JM;
James, S-N;
... Schott, JM; + view all
(2019)
Hippocampal subfield volumes and pre-clinical Alzheimer's disease in 408 cognitively normal adults born in 1946.
PLoS One
, 14
(10)
, Article e0224030. 10.1371/journal.pone.0224030.
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Parker, TD;
Slattery, CF;
Yong, KXX;
Nicholas, JM;
Paterson, RW;
Foulkes, AJM;
Malone, IB;
... Schott, JM; + view all
(2019)
Differences in hippocampal subfield volume are seen in phenotypic variants of early onset Alzheimer's disease.
NeuroImage: Clinical
, Article 101632. 10.1016/j.nicl.2018.101632.
(In press).
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Parker, TD;
Slattery, CF;
Zhang, J;
Nicholas, JM;
Paterson, RW;
Foulkes, AJM;
Malone, IB;
... Schott, JM; + view all
(2018)
Cortical microstructure in young onset Alzheimer's disease using neurite orientation dispersion and density imaging.
Human Brain Mapping
, 39
(7)
pp. 3005-3017.
10.1002/hbm.24056.
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Prosser, Lloyd;
MacDougall, Amy;
Sudre, Carole H;
Manning, Emily N;
Malone, Ian B;
Walsh, Phoebe;
Goodkin, Olivia;
... Barnes, Josephine; + view all
(2023)
Predicting Cognitive Decline in Nondemented Elders Using Baseline Metrics of AD Pathologies, Cerebrovascular Disease, and Neurodegeneration.
Neurology
, 100
(8)
e834-e845.
10.1212/WNL.0000000000201572.
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Prosser, Lloyd;
Sudre, Carole H;
Oxtoby, Neil P;
Young, Alexandra L;
Malone, Ian B;
Manning, Emily N;
Pemberton, Hugh;
... Barnes, Josephine; + view all
(2024)
Biomarker pathway heterogeneity of amyloid-positive individuals.
Alzheimer's & Dementia
, 20
(12)
pp. 8503-8515.
10.1002/alz.14287.
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Ryan, NS;
Keihaninejad, S;
Shakespeare, T;
Lehmann, M;
Crutch, SJ;
Malone, IB;
Thornton, JS;
... Fox, NC; + view all
(2013)
Magnetic resonance imaging evidence for presymptomatic change in thalamus and caudate in familial Alzheimer’s disease.
Brain
10.1093/brain/awt065.
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Scahill, Rachael I;
Farag, Mena;
Murphy, Michael J;
Hobbs, Nicola Z;
Leocadi, Michela;
Langley, Christelle;
Knights, Harry;
... Tabrizi, Sarah J; + view all
(2025)
Somatic CAG repeat expansion in blood associates with biomarkers of neurodegeneration in Huntington's disease decades before clinical motor diagnosis.
Nature Medicine
10.1038/s41591-024-03424-6.
(In press).
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Slattery, CF;
Malone, IB;
Clegg, SL;
Warren, JD;
Fox, NC;
(2015)
Reversible frontotemporal brain sagging syndrome.
Neurology
, 85
(9)
p. 833.
10.1212/WNL.0000000000001898.
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Soskic, Sonja;
Tregidgo, Henry FJ;
Todd, Emily G;
Bouzigues, Arabella;
Cash, David M;
Russell, Lucy L;
Thomas, David L;
... on behalf of the, GENetic Frontotemporal dementia Initiative (GENFI); + view all
(2025)
Thalamus involvement in genetic frontotemporal dementia assessed using structural and diffusion MRI: a GENFI study.
Brain Communications
, Article fcaf420. 10.1093/braincomms/fcaf420.
(In press).
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Veale, T;
Malone, IB;
Poole, T;
Parker, TD;
Slattery, CF;
Paterson, RW;
Foulkes, AJM;
... Cash, DM; + view all
(2021)
Loss and dispersion of superficial white matter in Alzheimer's disease: a diffusion MRI study.
Brain Communications
, 3
(4)
, Article fcab272. 10.1093/braincomms/fcab272.
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Weston, Philip SJ;
Coath, William;
Harris, Matthew J;
Malone, Ian B;
Dickson, John;
Aigbirhio, Franklin I;
Cash, David M;
... Schott, Jonathan M; + view all
(2023)
Cortical tau is associated with microstructural imaging biomarkers of neurite density and dendritic complexity in Alzheimer's disease.
Alzheimer's & Dementia
10.1002/alz.13011.
(In press).
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Weston, PSJ;
Poole, T;
Ryan, NS;
Nair, A;
Liang, Y;
Macpherson, K;
Druyeh, R;
... Fox, NC; + view all
(2018)
Accelerated long-term forgetting in presymptomatic Autosomal Dominant Alzheimer's disease: A cross-sectional study.
Lancet Neurology
, 17
(2)
pp. 123-132.
10.1016/S1474-4422(17)30434-9.
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Weston, PSJ;
Poole, T;
Ryan, NS;
Nair, A;
Liang, Y;
Macpherson, K;
Druyeh, R;
... Fox, NC; + view all
(2017)
Serum neurofilament light in familial Alzheimer disease: A marker of early neurodegeneration.
Neurology
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pp. 2167-2175.
10.1212/WNL.0000000000004667.
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Poster
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Cash, DM;
Burgos, N;
Modat, M;
Dickson, J;
Beasley, D;
Markiewicz, P;
Lane, CA;
... Schott, J; + view all
(2017)
A comparison of techniques for quantifying amyloid burden on a combined pet/mr scanner.
Presented at: Alzheimer's Association International Conference, London, United Kingdom.
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