Browse by UCL Department: listings for include files
- UCL (190490)
- UCL (190490)
- Provost and Vice Provost Offices (189276)
- School of Life and Medical Sciences (93077)
- Faculty of Medical Sciences (20967)
- Cancer Institute (3916)
- Research Department of Oncology (1304)
- Cancer Institute (3916)
- Faculty of Medical Sciences (20967)
- School of Life and Medical Sciences (93077)
- Provost and Vice Provost Offices (189276)
- UCL (190490)
Number of items at this level: 1304.
A
Abbas, A;
Tabish, TA;
Bull, SJ;
Lim, TM;
Phan, AN;
(2020)
High yield synthesis of graphene quantum dots from biomass waste as a highly selective probe for Fe3+ sensing.
Scientific Reports
, 10
, Article 21262. 10.1038/s41598-020-78070-2.
|
 |
|
Abbosh, C;
Swanton, C;
(2021)
ctDNA: An emerging neoadjuvant biomarker in resectable solid tumors.
PLoS Medicine
, 18
(10)
, Article e1003771. 10.1371/journal.pmed.1003771.
|
|
|
Abbosh, Christopher;
Frankell, Alexander M;
Harrison, Thomas;
Kisistok, Judit;
Garnett, Aaron;
Johnson, Laura;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2023)
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Nature
, 616
(7957)
pp. 553-562.
10.1038/s41586-023-05776-4.
|
|
Abbosh, C;
Birkbak, NJ;
Wilson, GA;
Jamal-Hanjani, M;
Constantin, T;
Salari, R;
Le Quesne, J;
... Dessimoz, C; + view all
(2017)
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.
Nature
, 545
pp. 446-451.
10.1038/nature22364.
|
|
Abbosh, C;
Swanton, C;
Birkbak, NJ;
(2018)
Circulating tumor DNA analyses reveal novel resistance mechanisms to CDK inhibition in metastatic breast cancer.
Annals of Oncology
10.1093/annonc/mdy017.
(In press).
|
|
|
Abbosh, C;
Venkatesan, S;
Janes, SM;
Fitzgerald, RC;
Swanton, C;
(2017)
Evolutionary dynamics in pre-invasive neoplasia.
Current Opinion in System Biology
, 2
pp. 1-8.
10.1016/j.coisb.2017.02.009.
|
|
Abbosh, Christopher;
(2021)
Cell-free DNA in early-stage non-small cell lung cancer.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Abdel-Aty, H;
O'Shea, L;
Amos, C;
Brown, LC;
Grist, E;
Attard, G;
Clarke, N;
... James, N; + view all
(2023)
The STAMPEDE2 Trial: a Site Survey of Current Patterns of Care, Access to Imaging and Treatment of Metastatic Prostate Cancer.
Clinical Oncology
, 35
(10)
e628-e635.
10.1016/j.clon.2023.07.009.
|
|
Abdollah, MRA;
(2016)
Developing superparamagnetic iron oxide nanoparticles as targeted cancer nanomedicine.
Doctoral thesis , UCL (University College London).
|
|
Abdollah, MRA;
Carter, TJ;
Jones, C;
Kalber, TL;
Rajkumar, V;
Tolner, B;
Gruettner, C;
... Chester, KA; + view all
(2018)
Fucoidan Prolongs the Circulation Time of Dextran-Coated Iron Oxide Nanoparticles.
ACS Nano
, 12
(2)
pp. 1156-1169.
10.1021/acsnano.7b06734.
|
|
Abdul-Jawad, S;
Baù, L;
Alaguthurai, T;
Del Molino Del Barrio, I;
Laing, AG;
Hayday, TS;
Monin, L;
... Irshad, S; + view all
(2021)
Acute immune signatures and their legacies in severe acute respiratory syndrome coronavirus-2 infected cancer patients.
Cancer Cell
10.1016/j.ccell.2021.01.001.
(In press).
|
|
|
AbdulJabbar, K;
Raza, SEA;
Rosenthal, R;
Jamal-Hanjani, M;
Veeriah, S;
Akarca, A;
Lund, T;
... Yuan, Y; + view all
(2020)
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma.
Nature Medicine
, 26
pp. 1054-1062.
10.1038/s41591-020-0900-x.
|
|
Abeyakoon, O;
Latifoltojar, A;
Gong, F;
Papoutsaki, M-V;
Chowdhury, R;
Glaser, M;
Jeraj, H;
... Punwani, S; + view all
(2019)
Hyperpolarised 13C MRI: a new horizon for non-invasive diagnosis of aggressive breast cancer.
BJR case reports
, 5
(3)
, Article 20190026. 10.1259/bjrcr.20190026.
|
|
|
Abou-Alfa, G;
Qin, S;
Ryoo, B-Y;
Lu, S-N;
Yen, C-J;
Feng, Y-H;
Lim, HY;
... Chen, L-T; + view all
(2018)
Phase III randomized study of second line ADI-PEG 20 plus best supportive care versus placebo plus best supportive care in patients with advanced hepatocellular carcinoma.
Annals of Oncology
, 29
(6)
pp. 1402-1408.
10.1093/annonc/mdy101.
|
|
Abou-Alfa, GK;
Meyer, T;
Cheng, A-L;
El-Khoueiry, AB;
Rimassa, L;
Ryoo, B-Y;
Cicin, I;
... Kelley, RK; + view all
(2018)
Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma.
New England Journal of Medicine
, 379
(1)
pp. 54-63.
10.1056/NEJMoa1717002.
|
|
Adams, RA;
Fisher, DJ;
Graham, J;
Seligmann, JF;
Seymour, M;
Kaplan, R;
Yates, E;
... FOCUS4 Trial Investigators; + view all
(2021)
Capecitabine Versus Active Monitoring in Stable or Responding Metastatic Colorectal Cancer After 16 Weeks of First-Line Therapy: Results of the Randomized FOCUS4-N Trial.
Journal of clinical oncology: official journal of the American Society of Clinical Oncology
10.1200/JCO.21.01436.
(In press).
|
|
|
Adams, R;
Brown, E;
Brown, L;
Butler, R;
Falk, S;
Fisher, D;
Kaplan, R;
... FOCUS4 Trial Investigators; + view all
(2018)
Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2–3 randomised trial.
The Lancet Gastroenterology & Hepatology
, 3
(3)
pp. 162-171.
10.1016/S2468-1253(17)30394-1.
|
|
|
Adeleke, S;
Latifoltojar, A;
Sidhu, H;
Galazi, M;
Shah, TT;
Clemente, J;
Davda, R;
... Punwani, S; + view all
(2019)
Localising occult prostate cancer metastasis with advanced imaging techniques (LOCATE trial): a prospective cohort, observational diagnostic accuracy trial investigating whole-body magnetic resonance imaging in radio-recurrent prostate cancer.
BMC Medical Imaging
, 19
, Article 90. 10.1186/s12880-019-0380-y.
|
|
|
Agbamu, DA;
Day, N;
Walsh, CJ;
Hendrickse, CW;
Langman, G;
Pallan, A;
Lowe, A;
... Lees, N; + view all
(2012)
Feasibility of preoperative chemotherapy for locally advanced, operable colon cancer: The pilot phase of a randomised controlled trial.
The Lancet Oncology
, 13
(11)
1152 - 1160.
10.1016/S1470-2045(12)70348-0.
|
 |
|
Agbuduwe, C;
Yang, H;
Gaglani, J;
Ajithkumar, T;
(2020)
Clinical presentation and outcomes of solitary plasmacytoma in a tertiary hospital in the UK.
Clinical Medicine Journal
, 20
(5)
e191-e195.
10.7861/clinmed.2019-0488.
|
|
Agbuduwe, Charles;
Iqbal, Gulnaz;
Cairns, David A;
Menzies, Tom;
Dunn, Janet;
Gregory, Walter Martin;
Kaiser, Martin F;
... Basu, Supratik; + view all
(2022)
Clinical Characteristics and Outcomes of IgD Myeloma: Experience across UK National Trials.
Blood Advances
10.1182/bloodadvances.2022007608.
(In press).
|
|
Agbuduwe, C;
Basu, S;
(2020)
Hematolological Manifestations of COVID-19: From Cytopenia to Coagulopathy.
European Journal of Haematology
10.1111/ejh.13491.
(In press).
|
|
|
Agerbæk, M;
Bang-Christensen, SR;
Yang, MH;
Clausen, TM;
Pereira, MA;
Sharma, S;
Ditlev, SB;
... Salanti, A; + view all
(2022)
Author Correction to: The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner (Nature Communications, (2018), 9, 1, (3279), 10.1038/s41467-018-05793-2).
Nature Communications
, 13
(1)
, Article 3285. 10.1038/s41467-022-29351-z.
|
|
Agerbæk, MØ;
Bang-Christensen, SR;
Yang, M-H;
Clausen, TM;
Pereira, MA;
Sharma, S;
Ditlev, SB;
... Salanti, A; + view all
(2018)
The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner.
Nature Communications
, 9
(1)
, Article 3279. 10.1038/s41467-018-05793-2.
|
|
|
Aggarwal, D;
Page, AJ;
Schaefer, U;
Savva, GM;
Myers, R;
Volz, E;
Ellaby, N;
... Harrison, EM; + view all
(2022)
Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission.
Nature Communications
, 13
, Article 1012. 10.1038/s41467-022-28371-z.
|
|
|
Ah-See, M-L.W.;
(2007)
Evaluation of the vascular response to neoadjuvant chemotherapy in primary breast cancer.
Doctoral thesis , University of London.
|
|
|
Ahmed, Mahbubl;
Collins, Shane;
Bacon, Andrew;
Franks, Joanna;
Lobo, Cheryl;
Paley, Lizz;
Strauss, Sandra;
(2021)
08. Incidence and outcome of breast sarcomas in NHS England (2013-2018): An analysis from Public Health England (PHE) National Cancer Registration and Analysis Service (NCRAS).
European Journal of Surgical Oncology
, 47
(5)
e288-e288.
10.1016/j.ejso.2021.03.204.
|
|
Ahmed, J;
Tabish, TA;
Zhang, S;
Edirisinghe, M;
(2020)
Porous Graphene Composite Polymer Fibres.
Polymers
, 13
(1)
, Article 76. 10.3390/polym13010076.
|
|
|
Ahrenfeldt, Johanne;
Christensen, Ditte S;
Sokac, Mateo;
Kisistok, Judit;
McGranahan, Nicholas;
Birkbak, Nicolai J;
(2022)
Computational Analysis Reveals the Temporal Acquisition of Pathway Alterations during the Evolution of Cancer.
Cancers
, 14
(23)
, Article 5817. 10.3390/cancers14235817.
|
|
Aitken, J;
Ambrose, K;
Barrell, S;
Beale, R;
Bineva-Todd, G;
Biswas, D;
Byrne, R;
... Wu, M; + view all
(2020)
Scalable and robust SARS-CoV-2 testing in an academic center.
Nature Biotechnology
, 38
(8)
pp. 927-931.
10.1038/s41587-020-0588-y.
|
|
|
Akay, M;
Funingana, I-G;
Patel, G;
Mustapha, R;
Gjafa, E;
Ng, T;
Ng, K;
(2021)
An In-Depth Review of Niraparib in Ovarian Cancer: Mechanism of Action, Clinical Efficacy and Future Directions.
Oncology and Therapy
10.1007/s40487-021-00167-z.
(In press).
|
|
|
Al Bakir, Maise;
(2020)
The Evolution of Metastases in Non-Small Cell Lung Cancer.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Al Bakir, Maise;
Huebner, Ariana;
Martínez-Ruiz, Carlos;
Grigoriadis, Kristiana;
Watkins, Thomas BK;
Pich, Oriol;
Moore, David A;
... Swanton, Charles; + view all
(2023)
The evolution of non-small cell lung cancer metastases in TRACERx.
Nature
10.1038/s41586-023-05729-x.
(In press).
|
|
Al Wattar, BH;
Rogozińska, E;
Vale, C;
Fisher, D;
Petersen, I;
Nicum, S;
Bannington, D;
... Freemantle, N; + view all
(2024)
Effectiveness and safety of menopause treatments: pitfalls of available evidence and future research need.
Climacteric
, 27
(2)
pp. 154-158.
10.1080/13697137.2023.2297880.
|
|
Al-Mossawi, H;
Yager, N;
Taylor, CA;
Lau, E;
Danielli, S;
de Wit, J;
Gilchrist, J;
... Fairfax, BP; + view all
(2019)
Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele.
Nature Communications
, 10
, Article 4575. 10.1038/s41467-019-12393-1.
|
|
|
Al-Qassab, Hind;
Smith, Mark A;
Irvine, Elaine E;
Guillermet-Guibert, Julie;
Claret, Marc;
Choudhury, Agharul I;
Selman, Colin;
... Withers, Dominic J; + view all
(2009)
Dominant Role of the p110β Isoform of PI3K over p110α in Energy Homeostasis Regulation by POMC and AgRP Neurons.
Cell Metabolism
, 10
(5)
pp. 343-354.
10.1016/j.cmet.2009.09.008.
|
|
Alexandrou, C;
Al-Aqbi, SS;
Higgins, JA;
Boyle, W;
Karmokar, A;
Andreadi, C;
Luo, J-L;
... Rufini, A; + view all
(2018)
Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes.
Scientific Reports
, 8
, Article 12096. 10.1038/s41598-018-30591-7.
|
|
|
Ali, A;
Hoyle, AP;
Parker, CC;
Brawley, CD;
Cook, A;
Amos, C;
Calvert, J;
... STAMPEDE investigators; + view all
(2021)
Bone metastatic burden as a predictor of survival benefit from prostate radiotherapy in newly-diagnosed metastatic prostate cancer.
JAMA oncology
, 7
(4)
pp. 555-563.
10.1001/jamaoncol.2020.7857.
|
|
|
Ali, A;
Plus 12 other authors, TPUWPO;
Sydes, M;
Clarke, NW;
(2020)
The Automated Bone Scan Index as a Predictor of Response to Prostate Radiotherapy in Men with Newly Diagnosed Metastatic Prostate Cancer: An Exploratory Analysis of STAMPEDE’s “M1|RT Comparison”.
European Urology Oncology
, 3
(4)
pp. 412-419.
10.1016/j.euo.2020.05.003.
|
|
|
Alifrangis, C;
McGovern, U;
Freeman, A;
Powles, T;
Linch, M;
(2019)
Molecular and histopathology directed therapy for advanced bladder cancer.
Nature Reviews Urology
, 16
(8)
pp. 465-483.
10.1038/s41585-019-0208-0.
|
|
|
Alliouachene, S;
Bilanges, B;
Chaussade, C;
Pearce, W;
Foukas, LC;
Scudamore, CL;
Moniz, LS;
(2016)
Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice.
Diabetologia
, 59
(7)
pp. 1503-1512.
10.1007/s00125-016-3963-y.
|
|
Alliouachene, S;
Bilanges, B;
Chicanne, G;
Anderson, KE;
Pearce, W;
Ali, K;
Valet, C;
... Vanhaesebroeck, B; + view all
(2015)
Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity.
Cell Reports
, 13
(9)
pp. 1881-1894.
10.1016/j.celrep.2015.10.052.
|
|
|
Alliouachene, S;
Kieswich, JE;
Bilanges, B;
McCafferty, K;
Thiemermann, C;
Vanhaesebroeck, B;
Yaqoob, MM;
(2021)
Uninephrectomy and class II PI3K-C2β inactivation synergistically protect against obesity, insulin resistance and liver steatosis in mice.
American Journal of Transplantation
10.1111/ajt.16470.
(In press).
|
|
|
Alonzi, R.;
(2008)
Evaluation of the oxygenation and vascularity of prostate cancer using magnetic resonance imaging.
Doctoral thesis , University of London.
|
|
|
Alrifai, D;
Forster, MD;
Janes, SM;
(2018)
Emerging resistance pathways in lung cancer: what has ROS-1 taught us?
[Editorial comment].
Translational Lung Cancer Research
, 7
(Suppl 1)
S9-S12.
10.21037/tlcr.2017.11.13.
|
|
|
Alwan, NA;
Burgess, RA;
Ashworth, S;
Beale, R;
Bhadelia, N;
Bogaert, D;
Dowd, J;
... Ziauddeen, H; + view all
(2020)
Scientific consensus on the COVID-19 pandemic: we need to act now.
The Lancet
, 396
(10260)
e71-e72.
10.1016/S0140-6736(20)32153-X.
|
|
|
Amir, A;
Porwal, H;
Mahalingam, S;
Wu, X;
Wu, T;
Chen, B;
Tabish, TA;
(2020)
Microstructure of fibres pressure-spun from polyacrylonitrile – graphene oxide composite mixtures.
Composites Science and Technology
, 197
, Article 108214. 10.1016/j.compscitech.2020.108214.
|
|
An, Z;
Flores-Borja, F;
Irshad, S;
Deng, J;
Ng, T;
(2020)
Pleiotropic Role and Bidirectional Immunomodulation of Innate Lymphoid Cells in Cancer.
Frontiers in Immunology
, 10
, Article 3111. 10.3389/fimmu.2019.03111.
|
|
|
Anderton, J;
Moroz, V;
Marec-Bérard, P;
Gaspar, N;
Laurence, V;
Martín-Broto, J;
Sastre, A;
... Brennan, B; + view all
(2020)
International randomised controlled trial for the treatment of newly diagnosed EWING sarcoma family of tumours - EURO EWING 2012 Protocol.
Trials
, 21
(1)
, Article 96. 10.1186/s13063-019-4026-8.
|
|
|
Ang, JE;
Pandher, R;
Ang, JC;
Asad, YJ;
Henley, A;
Valenti, M;
Box, G;
... Raynaud, FI; + view all
(2016)
Plasma metabolomic changes following PI3K inhibition as pharmacodynamic biomarkers: preclinical discovery to Phase I trial evaluation.
Molecular Cancer Therapeutics
, 15
(6)
pp. 1412-1424.
10.1158/1535-7163.MCT-15-0815.
|
|
Angeles, Martina Aida;
Boria, Felix;
Shushkevich, Alexander B;
Bizzarri, Nicolo;
Theofanakis, Charalampos;
Schivardi, Gabriella;
Kacperczyk-Bartnik, Joanna;
... Ramirez, Pedro T; + view all
(2023)
Interviews conducted at the European Society of Gynaecological Oncology 2022 Congress: a ENYGO-IJGC Fellows initiative.
International Journal of Gynecological Cancer
, 33
(1)
pp. 12-18.
10.1136/ijgc-2022-004160.
|
|
Angelis, A;
Montibeller, G;
Hochhauser, D;
Kanavos, P;
(2017)
Multiple criteria decision analysis in the context of health technology assessment: a simulation exercise on metastatic colorectal cancer with multiple stakeholders in the English setting.
BMC Medical Informatics and Decision Making
, 17
(1)
, Article 149. 10.1186/s12911-017-0524-3.
|
|
|
Anjos-Afonso, F;
Loizou, JI;
Bradburn, A;
Kanu, N;
Purewal, S;
Da Costa, C;
Bonnet, D;
(2016)
Perturbed hematopoiesis in mice lacking ATMIN.
Blood
, 128
(16)
pp. 2017-2021.
10.1182/blood-2015-09-672980.
|
|
|
Anquetil, T;
Solinhac, R;
Jaffre, A;
Chicanne, G;
Viaud, J;
Darcourt, J;
Orset, C;
... Gratacap, M-P; + view all
(2021)
PI3KC2β inactivation stabilizes VE-cadherin junctions and preserves vascular integrity.
EMBO Reports
, 22
(6)
, Article e51299. 10.15252/embr.202051299.
|
|
Anthoney, DA;
Naik, J;
MacPherson, IRJ;
Crawford, D;
Hartley, JM;
Hartley, JA;
Saito, T;
... Evans, TRJ; + view all
(2012)
Phase I study of TP300 in patients with advanced solid tumors with pharmacokinetic, pharmacogenetic and pharmacodynamic analyses.
BMC Cancer
, 12
, Article 536. 10.1186/1471-2407-12-536.
|
|
|
Arend, Rebecca C;
Monk, Bradley J;
Shapira-Frommer, Ronnie;
Haggerty, Ashley F;
Alvarez, Edwin A;
Amit, Amnon;
Alvarez Secord, Angeles;
... OVAL/GOG-3018 Investigators; + view all
(2023)
Ofranergene Obadenovec (Ofra-Vec, VB-111) With Weekly Paclitaxel for Platinum-Resistant Ovarian Cancer: Randomized Controlled Phase III Trial (OVAL Study/GOG 3018).
Journal of Clinical Oncology
, 42
(2)
pp. 170-179.
10.1200/JCO.22.02915.
|
|
Argiles, G;
Tabernero, J;
Labianca, R;
Hochhauser, D;
Salazar, R;
Iveson, T;
Laurent-Puig, P;
... ESMO Guidelines Committee; + view all
(2020)
Localised colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Annals of Oncology
, 31
(10)
pp. 1291-1305.
10.1016/j.annonc.2020.06.022.
|
|
Arkenau, H-T;
Italiano, A;
Mak, G;
Toulmonde, M;
Baird, RD;
Garcia-Corbacho, J;
Plummer, R;
... Spicer, J; + view all
(2018)
An extended phase Ib study of epertinib, an orally active reversible dual EGFR/HER2 tyrosine kinase inhibitor, in patients with solid tumours.
European Journal of Cancer
, 103
pp. 17-23.
10.1016/j.ejca.2018.07.134.
|
|
Arshad, R;
Tabish, TA;
Kiani, MH;
Ibrahim, IM;
Shahnaz, G;
Rahdar, A;
Kang, M;
(2021)
A Hyaluronic Acid Functionalized Self-Nano-Emulsifying Drug Delivery System (SNEDDS) for Enhancement in Ciprofloxacin Targeted Delivery against Intracellular Infection.
Nanomaterials
, 11
(5)
, Article 1086. 10.3390/nano11051086.
|
|
|
Arya, M;
Thrasivoulou, C;
Henrique, R;
Millar, M;
Hamblin, R;
Davda, R;
Aare, K;
... Ahmed, A; + view all
(2015)
Targets of Wnt/ß-catenin transcription in penile carcinoma.
PLoS One
, 10
(4)
, Article e0124395. 10.1371/journal.pone.0124395.
|
|
|
Ashford, F;
Best, A;
Dunn, SJ;
Ahmed, Z;
Siddiqui, H;
Melville, J;
Wilkinson, S;
... Jamrozy, D; + view all
(2022)
SARS-CoV-2 Testing in the Community: Testing Positive Samples with the TaqMan SARS-CoV-2 Mutation Panel To Find Variants in Real Time.
Journal of Clinical Microbiology
, 60
(4)
, Article e02408-21. 10.1128/jcm.02408-21.
|
|
Astier, Clemence;
Ngo, Carine;
Colmet-Daage, Leo;
Marty, Virginie;
Bawa, Olivia;
Nicotra, Claudio;
Ngo-Camus, Maud;
... Postel-Vinay, Sophie; + view all
(2024)
Molecular profiling of biliary tract cancers reveals distinct genomic landscapes between circulating and tissue tumor DNA.
Experimental Hematology & Oncology
, 13
(1)
, Article 2. 10.1186/s40164-023-00470-7.
|
|
Attard, G;
Brown, LC;
Clarke, NW;
Parmar, MKB;
James, ND;
(2021)
Should Patients with High-risk Localised or Locally Advanced Prostate Cancer Receive Abiraterone Acetate in Addition to Androgen Deprivation Therapy? Update on a Planned Analysis of the STAMPEDE Trial.
European Urology
, 80
(4)
pp. 522-523.
10.1016/j.eururo.2021.06.023.
|
|
Attard, G;
Murphy, L;
Clarke, NW;
Cross, W;
Jones, RJ;
Parker, CC;
Gillessen, S;
... Systemic Therapy in Advancing or Metastatic Prostate cancer: Eva; + view all
(2021)
Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol.
The Lancet
10.1016/S0140-6736(21)02437-5.
(In press).
|
|
Attard, G;
Murphy, L;
Clarke, NW;
Sachdeva, A;
Jones, C;
Hoyle, A;
Cross, W;
... McPhail, N; + view all
(2023)
Abiraterone acetate plus prednisolone with or without enzalutamide for patients with metastatic prostate cancer starting androgen deprivation therapy: final results from two randomised phase 3 trials of the STAMPEDE platform protocol.
The Lancet Oncology
, 24
(5)
pp. 443-456.
10.1016/S1470-2045(23)00148-1.
|
|
|
Attard, G;
Antonarakis, ES;
(2016)
Prostate cancer: AR aberrations and resistance to abiraterone or enzalutamide.
Nature Reviews Urology
, 13
(12)
pp. 697-698.
10.1038/nrurol.2016.212.
|
|
|
Attard, G;
Borre, M;
Gurney, H;
Loriot, Y;
Andresen-Daniil, C;
Kalleda, R;
Trinh, P;
(2018)
Abiraterone Alone or in Combination With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer With Rising Prostate-Specific Antigen During Enzalutamide Treatment.
Journal of Clinical Oncology
, 36
(25)
pp. 2639-2646.
10.1200/JCO.2018.77.9827.
|
|
|
Attard, G;
Conteduca, V;
Wetterskog, D;
(2019)
A multimodal approach to outcome prediction in metastatic castration-resistant prostate cancer by integrating functional imaging and plasma DNA analysis.
JCO Precision Oncology
10.1200/PO.18.00302.
(In press).
|
|
Attard, G;
Jayaram, A;
Wingate, A;
Wetterskog, K;
(2019)
Plasma Androgen Receptor Copy Number Status at Emergence of Metastatic Castration-Resistant Prostate Cancer: A Pooled Multicohort Analysis.
JCO Precision Oncology
, 3
10.1200/PO.19.00123.
|
|
Attard, G;
Merseburger, AS;
Arlt, W;
Sternberg, CN;
Feyerabend, S;
Berruti, A;
Joniau, S;
... Tombal, B; + view all
Assessment of the Safety of Glucocorticoid Regimens in Combination With Abiraterone Acetate: A Randomized, Open-Label Phase 2 Study.
JAMA Oncology
10.1001/jamaoncol.2019.1011.
(In press).
|
|
|
Attard, G;
Wetterskog, D;
Jayaram, A;
Wingate, A;
(2019)
Plasma AR status and cabazitaxel in heavily-treated metastatic castration-resistant prostate cancer.
European Journal of Cancer
, 116
pp. 158-168.
10.1016/j.ejca.2019.05.007.
|
|
Au, L;
Hatipoglu, E;
Robert de Massy, M;
Litchfield, K;
Beattie, G;
Rowan, A;
Schnidrig, D;
... TRACERx Renal Consortium; + view all
(2021)
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma.
Cancer Cell
, 39
pp. 1497-1518.
10.1016/j.ccell.2021.10.001.
|
|
|
Au, L;
Fendler, A;
Shepherd, STC;
Rzeniewicz, K;
Cerrone, M;
Byrne, F;
Carlyle, E;
... Turajlic, S; + view all
(2021)
Cytokine release syndrome in a patient with colorectal cancer after vaccination with BNT162b2.
Nature Medicine
10.1038/s41591-021-01387-6.
|
|
|
Azad, AK;
Zhabyeyev, P;
Vanhaesebroeck, B;
Eitzen, G;
Oudit, GY;
Moore, RB;
Murray, AG;
(2020)
Inactivation of endothelial cell phosphoinositide 3-kinase β inhibits tumor angiogenesis and tumor growth.
Oncogene
, 39
pp. 6480-6492.
10.1038/s41388-020-01444-3.
|
B
|
Bahleda, R;
Meric-Bernstam, F;
Goyal, L;
Tran, B;
He, Y;
Yamamiya, I;
Benhadji, KA;
... Arkenau, H-T; + view all
(2020)
Phase I, first-in-human study of futibatinib, a highly selective, irreversible FGFR1-4 inhibitor in patients with advanced solid tumors.
Annals of Oncology
10.1016/j.annonc.2020.06.018.
(In press).
|
|
|
Bahri, M;
Anstee, JE;
Opzoomer, JW;
Arnold, JN;
(2023)
Perivascular tumor-associated macrophages and their role in cancer progression.
Essays in Biochemistry
, 67
(6)
pp. 919-928.
10.1042/EBC20220242.
|
|
|
Bailey, C;
Black, JRM;
Reading, JL;
Litchfield, K;
Turajlic, S;
McGranahan, N;
Jamal-Hanjani, M;
(2021)
Tracking Cancer Evolution through the Disease Course.
Cancer Discovery
, 11
(4)
pp. 916-932.
10.1158/2159-8290.CD-20-1559.
|
|
Bailey, Chris;
Pich, Oriol;
Thol, Kerstin;
Watkins, Thomas BK;
Luebeck, Jens;
Rowan, Andrew;
Stavrou, Georgia;
... Swanton, Charles; + view all
(2024)
Origins and impact of extrachromosomal DNA.
Nature
, 635
(8037)
pp. 193-200.
10.1038/s41586-024-08107-3.
|
|
|
Bailey, Christopher;
(2024)
The prevalence, mutagenesis and evolution of focal copy number amplifications and extrachromosomal DNA in cancer.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
|
Bailey, C;
Black, JRM;
Swanton, C;
(2020)
Cancer Research: The Lessons to Learn from COVID-19.
Cancer Discovery
, 10
(9)
pp. 1263-1266.
10.1158/2159-8290.CD-20-0823.
|
|
Bailey, C;
Shoura, MJ;
Mischel, PS;
Swanton, C;
(2020)
Extrachromosomal DNA d relieving heredity constraints, accelerating tumour evolution.
Annals of Oncology
, 31
(7)
pp. 884-893.
10.1016/j.annonc.2020.03.303.
|
|
Bakhoum, SF;
Ngo, B;
Laughney, AM;
Cavallo, J-A;
Murphy, CJ;
Ly, P;
Shah, P;
... Cantley, LC; + view all
(2018)
Chromosomal instability drives metastasis through a cytosolic DNA response.
Nature
, 553
(7689)
pp. 467-472.
10.1038/nature25432.
|
|
|
Balestrini, S;
Koepp, MJ;
Gandhi, S;
Rickman, HM;
Yen Shin, G;
Houlihan, CF;
Anders-Cannon, J;
... Sisodiya, SM; + view all
(2021)
Clinical outcomes of COVID-19 in long-term care facilities for people with epilepsy.
Epilepsy & Behavior
, 115
, Article 107602. 10.1016/j.yebeh.2020.107602.
|
|
Balukova, Andrea;
Bokea, Kalliopi;
Barber, Paul R;
Ameer-Beg, Simon M;
MacRobert, Alexander J;
Yaghini, Elnaz;
(2024)
Cellular Imaging and Time-Domain FLIM Studies of Meso-Tetraphenylporphine Disulfonate as a Photosensitising Agent in 2D and 3D Models.
International Journal of Molecular Sciences
, 25
(8)
, Article 4222. 10.3390/ijms25084222.
|
|
Banerjee, S;
Tovey, H;
Bowen, R;
Folkerd, E;
Kilburn, L;
McLachlan, J;
Hall, M;
... Bliss, JM; + view all
(2020)
Abiraterone in patients with recurrent epithelial ovarian cancer: principal results of the phase II Cancer of the Ovary Abiraterone (CORAL) trial (CRUK-A16037).
Therapeutic Advances in Medical Oncology
, 12
, Article ARTN 175. 10.1177/1758835920975352.
|
|
|
Banfill, K;
Croxford, W;
Fornacon-Wood, I;
Wicks, K;
Ahmad, S;
Britten, A;
Carson, C;
... Faivre-Finn, C; + view all
(2021)
Changes in the Management of Patients having Radical Radiotherapy for Lung Cancer during the First Wave of the COVID-19 Pandemic in the UK.
Clinical Oncology
10.1016/j.clon.2021.10.009.
(In press).
|
|
|
Barata, PC;
De Liano, AG;
Mendiratta, P;
Crolley, V;
Szabados, B;
Morrison, L;
Wood, L;
... Rini, BI; + view all
(2018)
The efficacy of VEGFR TKI therapy after progression on immune combination therapy in metastatic renal cell carcinoma.
British Journal of Cancer
, 119
(2)
pp. 160-163.
10.1038/s41416-018-0104-z.
|
|
|
Barber, Paul R;
Mustapha, Rami;
Flores-Borja, Fabian;
Alfano, Giovanna;
Ng, Kenrick;
Weitsman, Gregory;
Dolcetti, Luigi;
... Ng, Tony; + view all
(2022)
Predicting progression-free survival after systemic therapy in advanced head and neck cancer: Bayesian regression and model development.
eLife
, 11
, Article e73288. 10.7554/eLife.73288.
|
|
Barber, L.J.;
(2004)
The Saccharomyces cerevisiae Snm1 gene and repair of anticancer drug-induced DNA interstrand cross-links.
Doctoral thesis , University of London.
|
|
|
Barber, PR;
Weitsman, G;
Lawler, K;
Barrett, J;
Rowley, M;
Rodriguez-Justo, M;
Fisher, D;
... Ng, T; + view all
(2019)
HER2-HER3 heterodimer quantification by FRET-FLIM and patient subclass analysis of the COIN colorectal trial.
JNCI: Journal of the National Cancer Institute
10.1093/jnci/djz231.
(In press).
|
|
|
Barbieri, CE;
Chinnaiyan, AM;
Lerner, SP;
Swanton, C;
Rubin, MA;
(2017)
The Emergence of Precision Urologic Oncology: A Collaborative Review on Biomarker-driven Therapeutics.
European Urology
, 71
(2)
pp. 237-246.
10.1016/j.eururo.2016.08.024.
|
|
|
Barnes, Josephine L;
Yoshida, Masahiro;
He, Peng;
Worlock, Kaylee B;
Lindeboom, Rik GH;
Suo, Chenqu;
Pett, J Patrick;
... Nikolić, Marko Z; + view all
(2023)
Early human lung immune cell development and its role in epithelial cell fate.
Science Immunology
, 8
(90)
, Article eadf9988. 10.1126/sciimmunol.adf9988.
|
|
Barrett, JE;
Feber, A;
Herrero, J;
Tanic, M;
Wilson, GA;
Swanton, C;
Beck, S;
(2017)
Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection.
BMC Bioinformatics
, 18
, Article 354. 10.1186/s12859-017-1753-2.
|
|
Bartlett, JMS;
Bayani, J;
Kornaga, E;
Xu, K;
Pond, GR;
Piper, T;
Mallon, E;
... Rea, D; + view all
(2021)
Comparative survival analysis of multiparametric tests-when molecular tests disagree-A TEAM Pathology study.
NPJ Breast Cancer
, 7
(1)
, Article 90. 10.1038/s41523-021-00297-7.
|
|
|
Bartlett, JMS;
Bayani, J;
Kornaga, EN;
Danaher, P;
Crozier, C;
Piper, T;
Yao, CQ;
... Stein, RC; + view all
(2020)
Computational approaches to support comparative analysis of multiparametric tests: Modelling versus Training.
PLOS ONE
, 15
(9)
, Article e0238593. 10.1371/journal.pone.0238593.
|
|
|
Bassey-Archibong, Blessing Iquo;
Rajendra Chokshi, Chirayu;
Aghaei, Nikoo;
Kieliszek, Agata Monika;
Tatari, Nazanin;
McKenna, Dillon;
Singh, Mohini;
... Singh, Sheila Kumari; + view all
(2023)
An HLA-G/SPAG9/STAT3 axis promotes brain metastases.
Proceedings of the National Academy of Sciences (PNAS)
, 120
(8)
, Article e2205247120. 10.1073/pnas.2205247120.
|
|
Baurain, J;
Awada, A;
Brunsvig, P;
Kristeleit, RS;
Loirat, D;
Jossang, D;
Zitvogel, L;
... Spicer, J; + view all
(2017)
A phase I dose escalation study of intra-tumoral LTX-315 as monotherapy or in combination with either ipilimumab or pembrolizumab in patients with transdermally accessible tumors (NCT01986426).
Presented at: AACR Annual Meeting 2017, Washington, D.C., USA.
|
|
Beaton, Laura;
Tregidgo, Henry Fj;
Znati, Sami A;
Forsyth, Sharon;
Counsell, Nicholas;
Clarkson, Matthew J;
Bandula, Steven;
... Sharma, Ricky A; + view all
(2022)
Phase 0 study of vandetanib-eluting radiopaque embolics as a pre-operative embolization treatment in patients with resectable liver malignancies.
Journal of Vascular and Interventional Radiology
, 33
(9)
1034-1044.e29.
10.1016/j.jvir.2022.04.033.
|
|
Beaton, L;
Tregidgo, HFJ;
Znati, SA;
Forsyth, S;
Clarkson, MJ;
Bandula, S;
Chouhan, M;
... Sharma, RA; + view all
(2019)
VEROnA Protocol: A Pilot, Open-Label, Single-Arm, Phase 0, Window-of-Opportunity Study of Vandetanib-Eluting Radiopaque Embolic Beads (BTG-002814) in Patients With Resectable Liver Malignancies.
JMIR Research Protocols
, 8
(10)
, Article e13696. 10.2196/13696.
|
|
|
Bedran, Georges;
Gasser, Hans-Christof;
Weke, Kenneth;
Wang, Tongjie;
Bedran, Dominika;
Laird, Alexander;
Battail, Christophe;
... Alfaro, Javier A; + view all
(2023)
The Immunopeptidome from a Genomic Perspective: Establishing the Noncanonical Landscape of MHC Class I–Associated Peptides.
Cancer Immunology Research
, 11
(6)
pp. 747-762.
10.1158/2326-6066.CIR-22-0621.
|
|
Beedham, W;
Peck, G;
Richardson, S;
Tsang, K;
Fertleman, M;
Shipway, D;
(2019)
Head injury in the elderly – an overview for the physician.
Clinical Medicine
, 19
(2)
pp. 177-184.
10.7861/clinmedicine.19-2-177.
|
|
Beird, H;
Bielack, Stefan;
Flanagan, Adrienne;
Gill, B;
Heymann, Dominique;
Janeway, Katherine;
Livingston, JA;
... Gorlick, Richard; + view all
(2022)
Osteosarcoma.
Nature Reviews Disease Primers
, 8
, Article 77. 10.1038/s41572-022-00409-y.
|
|
Belderbos, BPSI;
de Wit, R;
Chien, C;
Mitselos, A;
Hellemans, P;
Jiao, J;
Yu, MK;
... Saad, F; + view all
(2018)
An open-label, multicenter, phase Ib study investigating the effect of apalutamide on ventricular repolarization in men with castration-resistant prostate cancer.
Cancer Chemotherapy and Pharmacology
, 82
(3)
pp. 457-468.
10.1007/s00280-018-3632-6.
|
|
|
Bell, R;
Kirkwood, A;
Hargrave, D;
Michalski, A;
Hyare, H;
Jacques, T;
Stoneham, S;
... Shankar, A; + view all
(2020)
Disseminated Low Grade Glioma in Children and Young Adults.
ARC Journal of Cancer Science
, 6
(1)
pp. 7-18.
10.20431/2455-6009.0601002.
|
|
Bell, L;
Potts, H;
Williamson, E;
(2019)
P-17
Improving engagement in a health app: considerations in
designing a Micro-Randomised Trial.
Presented at: The 5th International Clinical Trials Methodology Conference (ICTMC 2019).
|
|
|
Bendell, JC;
Patel, MR;
Yoshida, K;
Seraj, J;
Weaver, R;
Lemech, C;
Todaro, TG;
... Arkenau, H-T; + view all
(2016)
Phase 1 study of cardiac safety of TAS-102 in patients with advanced solid tumors.
Cancer Chemother Pharmacol
, 77
(6)
pp. 1275-1283.
10.1007/s00280-016-3031-9.
|
|
|
Bentham, R;
Litchfield, K;
Watkins, TBK;
Lim, EL;
Rosenthal, R;
Martinez-Ruiz, C;
Hiley, CT;
... McGranahan, N; + view all
(2021)
Using DNA sequencing data to quantify T cell fraction and therapy response.
Nature
, 597
pp. 555-560.
10.1038/s41586-021-03894-5.
|
|
Bentham, RB;
(2016)
A bioinfomatic analysis of the role of mitochondrial biogenesis in human pathologies.
Doctoral thesis , UCL (University College London).
|
|
Bentham, RB;
Bryson, K;
Szabadkai, G;
(2019)
Biclustering Analysis of Co-regulation Patterns in Nuclear-Encoded Mitochondrial Genes and Metabolic Pathways.
Cancer Metabolism
, 1928
pp. 469-478.
10.1007/978-1-4939-9027-6_24.
|
|
Bentham, RB;
Bryson, K;
Szabadkai, G;
(2017)
MCbiclust: a novel algorithm to discover large-scale functionally related gene sets from massive transcriptomics data collections.
Nucleic Acids Research
, 45
(15)
pp. 8712-8730.
10.1093/nar/gkx590.
|
|
|
Bentzen, AK;
Marquard, AM;
Lyngaa, R;
Saini, SK;
Ramskov, S;
Donia, M;
Such, L;
... Hadrup, SR; + view all
(2016)
Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes.
Nature Biotechnology
, 34
(10)
pp. 1037-1045.
10.1038/nbt.3662.
|
|
|
Berenjeno, IM;
Piñeiro, R;
Castillo, SD;
Pearce, W;
McGranahan, N;
Dewhurst, SM;
Meniel, V;
... Vanhaesebroeck, B; + view all
(2017)
Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.
Nature Communications
, 8
, Article 1773. 10.1038/s41467-017-02002-4.
|
 |
|
Bertaglia, V;
Reale, ML;
Bironzo, P;
Palesandro, E;
Mariniello, A;
Leone, G;
Tabbò, F;
... Novello, S; + view all
(2021)
Italian survey on the clinical management of non-small cell lung cancer patients during the COVID-19 pandemic: A lesson for the second wave.
Critical Reviews in Oncology/Hematology
, 157
, Article 103189. 10.1016/j.critrevonc.2020.103189.
|
|
Best, J;
Starkey, T;
Chaterjee, A;
Fackrell, D;
Pettit, L;
Srihari, N;
Tween, H;
... Lee, LYW; + view all
(2021)
Coronavirus Disease 2019: the Pivotal Role of UK Clinical Oncology and the UK Coronavirus Cancer Monitoring Project.
Clinical Oncology
, 33
(1)
e50-e53.
10.1016/j.clon.2020.05.021.
|
|
Bewicke-Copley, Findlay;
Korfi, Koorosh;
Araf, Shamza;
Hodkinson, Brendan;
Kumar, Emil;
Cummin, Thomas;
Ashton-Key, Margaret;
... Fitzgibbon, Jude; + view all
(2023)
Longitudinal expression profiling identifies a poor risk subset of patients with ABC-type diffuse large B-cell lymphoma.
Blood Advances
, 7
(5)
pp. 845-855.
10.1182/bloodadvances.2022007536.
|
|
Bi, WL;
Hosny, A;
Schabath, MB;
Giger, ML;
Birkbak, NJ;
Mehrtash, A;
Allison, T;
... Aerts, HJWL; + view all
(2019)
Artificial intelligence in cancer imaging: Clinical challenges and applications.
CA: A Cancer Journal for Clinicians
, 69
(2)
pp. 127-157.
10.3322/caac.21552.
|
|
|
Bilancio, A;
Rinaldi, B;
Oliviero, MA;
Donniacuo, M;
Monti, MG;
Boscaino, A;
Marino, I;
... Migliaccio, A; + view all
(2017)
Inhibition of p110δ PI3K prevents inflammatory response and restenosis after artery injury.
Bioscience Reports
, 37
(5)
, Article BSR20171112. 10.1042/BSR20171112.
|
|
Bilanges, B;
Alliouachene, S;
Pearce, W;
Morelli, D;
Szabadkai, G;
Chung, Y-L;
Chicanne, G;
... Vanhaesebroeck, B; + view all
(2017)
Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism.
Nature Communications
, 8
, Article 1804. 10.1038/s41467-017-01969-4.
|
|
|
Bilanges, B;
Posor, Y;
Vanhaesebroeck, B;
(2019)
PI3K isoforms in cell signalling and vesicle trafficking.
Nature Reviews Molecular Cell Biology
, 20
pp. 515-534.
10.1038/s41580-019-0129-z.
|
|
Bilioni, A.;
(2005)
DNA binding specificities and transcriptional activity of mirror, an Iroquois transcription factor in Drosophila melanogaster.
Doctoral thesis , University of London.
|
|
|
Bird, TG;
Müller, M;
Boulter, L;
Vincent, DF;
Ridgway, RA;
Lopez-Guadamillas, E;
Lu, W-Y;
... Forbes, SJ; + view all
(2018)
TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence.
Science Translational Medicine
, 10
(454)
, Article eaan1230. 10.1126/scitranslmed.aan1230.
|
|
|
Birkbak, NJ;
McGranahan, N;
(2020)
Cancer Genome Evolutionary Trajectories in Metastasis.
Cancer Cell
, 37
(1)
pp. 8-19.
10.1016/j.ccell.2019.12.004.
|
|
Birley, K;
Chester, K;
Anderson, J;
(2018)
Antibody based therapy for childhood solid cancers.
Current Opinion in Chemical Engineering
, 19
pp. 153-162.
10.1016/j.coche.2018.01.005.
|
|
Biswas, Dhruva;
Kanu, Nnennaya;
Swanton, Charles;
(2025)
Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma
adenocarcinoma.
Nature Cancer
10.1038/s43018-024-00883-1.
(In press).
|
|
Biswas, D;
Birkbak, NJ;
Rosenthal, R;
Hiley, CT;
Lim, EL;
Papp, K;
Boeing, S;
... TRACERx Consortium; + view all
(2019)
A clonal expression biomarker associates with lung cancer mortality.
Nature Medicine
, 25
pp. 1540-1548.
10.1038/s41591-019-0595-z.
|
|
Black, James RM;
Bartha, Gabor;
Abbott, Charles W;
Boyle, Sean M;
Karasaki, Takahiro;
Li, Bailiang;
Chen, Rui;
... Swanton, Charles; + view all
(2025)
Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma.
Nature Medicine
, 31
pp. 70-76.
10.1038/s41591-024-03216-y.
|
|
|
Black, JRM;
McGranahan, N;
(2021)
Genetic and non-genetic clonal diversity in cancer evolution.
Nature Reviews Cancer
, 21
(6)
pp. 379-392.
10.1038/s41568-021-00336-2.
|
|
Black, JR;
Goldin, RD;
Foxton, M;
Marafioti, T;
Akarca, AU;
Pria, AD;
Brock, C;
... Pinato, DJ; + view all
(2019)
PD-L1 expressing granulomatous reaction as an on-target mechanism of steroid-refractory immune hepatotoxicity.
Immunotherapy
, 11
(7)
pp. 585-590.
10.2217/imt-2018-0187.
|
|
Black, JRM;
Bailey, C;
Przewrocka, J;
Dijkstra, KK;
Swanton, C;
(2020)
COVID-19: the case for health-care worker screening to prevent hospital transmission.
The Lancet
, 395
(10234)
pp. 1418-1420.
10.1016/S0140-6736(20)30917-X.
|
|
|
Blagih, J;
Zani, F;
Chakravarty, P;
Hennequart, M;
Pilley, S;
Hobor, S;
Hock, AK;
... Vousden, KH; + view all
(2020)
Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses.
Cell Reports
, 30
(2)
481-496.e6.
10.1016/j.celrep.2019.12.028.
|
|
|
Blake, Sophia M;
Stricker, Stefan H;
Halavach, Hanna;
Poetsch, Anna R;
Cresswell, George;
Kelly, Gavin;
Kanu, Nnennaya;
... Behrens, Axel; + view all
(2016)
Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation.
eLife
, 5
, Article e08711. 10.7554/eLife.08711.
|
|
|
Blakely, CM;
Watkins, TBK;
Wu, W;
Gini, B;
Chabon, JJ;
McCoach, CE;
McGranahan, N;
... Bivona, TG; + view all
(2017)
Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers.
Nature Genetics
, 49
(12)
pp. 1693-1704.
10.1038/ng.3990.
|
|
|
Blas, P;
Tolner, B;
Ward, J;
Chester, K;
Hoare, M;
(2018)
The use of a surface active agent in the protection of a fusion protein during bioprocessing.
Biotechnology and Bioengineering
, 115
(11)
pp. 2760-2770.
10.1002/bit.26817.
|
|
|
Boere, Ingrid;
Vergote, Ignace;
Hanssen, Rob;
Jalving, Mathilde;
Gennigens, Christine;
Ottevanger, Petronella;
van de Wouw, Yes J;
... Ledermann, Jonathan; + view all
(2023)
CINOVA: a phase II study of CPC634 (nanoparticulate docetaxel) in patients with platinum resistant recurrent ovarian cancer.
International Journal of Gynecologic Cancer
, 33
(8)
pp. 1247-1252.
10.1136/ijgc-2023-004308.
|
|
Bofinger, R;
Weitsman, G;
Evans, R;
Glaser, M;
Sander, K;
Allan, H;
Hochhauser, D;
... Tabor, AB; + view all
(2021)
Drug delivery, biodistribution and anti-EGFR activity: theragnostic nanoparticles for simultaneous in vivo delivery of tyrosine kinase inhibitors and kinase activity biosensors.
Nanoscale
10.1039/d1nr02770k.
(In press).
|
|
|
Bogani, G;
Moore, KN;
Ray-Coquard, I;
Lorusso, D;
Matulonis, UA;
Ledermann, JA;
González-Martín, A;
... Monk, BJ; + view all
(2025)
Incorporating immune checkpoint inhibitors in epithelial ovarian cancer.
Gynecologic Oncology
, 193
pp. 30-40.
10.1016/j.ygyno.2024.12.011.
|
|
Böiers, C;
Richardson, SE;
Laycock, E;
Zriwil, A;
Turati, VA;
Brown, J;
Wray, JP;
... Enver, T; + view all
(2018)
A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1.
Developmental Cell
, 44
(3)
pp. 362-377.
10.1016/j.devcel.2017.12.005.
|
|
Boire, Adrienne;
Burke, Katy;
Cox, Thomas R;
Guise, Theresa;
Jamal-Hanjani, Mariam;
Janowitz, Tobias;
Kaplan, Rosandra;
... Sahai, Erik; + view all
(2024)
Why do patients with cancer die?
Nature Reviews Cancer
, 24
(8)
pp. 578-589.
10.1038/s41568-024-00708-4.
|
|
|
Bonaca, Marc P;
Moslehi, Javid J;
Ledermann, Jonathan A;
Michelon, Elisabete;
Wei, Caimiao;
Moran, Michael;
Monk, Bradley J;
(2023)
Left Ventricular Ejection Fraction in Patients With Ovarian Cancer Treated With Avelumab, Pegylated Liposomal Doxorubicin, or Both.
The Oncologist
, 28
(10)
e977-e980.
10.1093/oncolo/oyad213.
|
|
|
Bono, P;
Massard, C;
Peltola, KJ;
Azaro, A;
Italiano, A;
Kristeleit, RS;
Curigliano, G;
... Rodon, JA; + view all
(2020)
Phase I/IIa, open-label, multicentre study to evaluate the optimal dosing and safety of ODM-203 in patients with advanced or metastatic solid tumours.
ESMO Open
, 5
(6)
, Article e001081. 10.1136/esmoopen-2020-001081.
|
|
|
Boone, J.J.M.;
(2007)
The role of ErbB2 and BRCA1 in repair of drug-induced DNA damage.
Doctoral thesis , University of London.
|
|
|
Booth, S;
Curley, HM;
Varnai, C;
Arnold, R;
Lee, LYW;
Campton, NA;
Cook, G;
... Palles, C; + view all
(2021)
Key findings from the UKCCMP cohort of 877 patients with haematological malignancy and COVID-19: disease control as an important factor relative to recent chemotherapy or anti-CD20 therapy.
British Journal of Haematology
10.1111/bjh.17937.
(In press).
|
|
|
Bortolomeazzi, M;
Keddar, MR;
Montorsi, L;
Acha-Sagredo, A;
Benedetti, L;
Temelkovski, D;
Choi, S;
... Ciccarelli, FD; + view all
(2021)
Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts.
Gastroenterology
10.1053/j.gastro.2021.06.064.
(In press).
|
|
|
Bosch-Vilaro, A;
Jacobs, B;
Pomella, V;
Asbagh, LA;
Kirkland, R;
Michel, J;
Singh, S;
... Tejpar, S; + view all
(2017)
Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells.
Oncotarget
, 8
(3)
pp. 4277-4288.
10.18632/oncotarget.13834.
|
|
Bosse, T;
Creutzberg, CL;
Crosbie, EJ;
Han, K;
Horeweg, N;
Leary, A;
Kroep, JR;
... RAINBO, Res Consortium; + view all
(2023)
Refining adjuvant treatment in endometrial cancer based on molecular features: the RAINBO clinical trial program.
International Journal of Gynecological Cancer
, 33
(1)
pp. 109-117.
10.1136/ijgc-2022-004039.
|
|
Boumelha, Jesse;
de Carné Trécesson, Sophie;
Law, Emily K;
Romero-Clavijo, Pablo;
Coelho, Matthew;
Ng, Kevin;
Mugarza, Edurne;
... Downward, Julian; + view all
(2022)
An Immunogenic Model of KRAS-Mutant Lung Cancer Enables Evaluation of Targeted Therapy and Immunotherapy Combinations.
Cancer Research
, 82
(19)
pp. 3435-3448.
10.1158/0008-5472.CAN-22-0325.
|
|
Brandner, SGP;
Jaunmuktane, Z;
Capper, D;
Jones, DTW;
Sill, M;
Hovestadt, V;
Schrimpf, D;
... Pfister, SM; + view all
(2018)
DNA methylation-based classification of central nervous system tumours.
Nature. International Journal of Science
, 555
pp. 469-474.
10.1038/nature26000.
|
|
Braso-Maristany, F;
Filosto, S;
Catchpole, S;
Marlow, R;
Quist, J;
Francesch-Domenech, E;
Plumb, DA;
... Tutt, AN; + view all
(2016)
PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.
Nature Medicine
, 22
(11)
pp. 1303-1313.
10.1038/nm.4198.
|
|
|
Brennan, B;
Kirton, L;
Marec-Bérard, P;
Gaspar, N;
Laurence, V;
Martín-Broto, J;
Sastre, A;
... Wheatley, K; + view all
(2022)
Comparison of two chemotherapy regimens in patients with newly diagnosed Ewing sarcoma (EE2012): an open-label, randomised, phase 3 trial.
The Lancet
, 400
(10362)
pp. 1513-1521.
10.1016/S0140-6736(22)01790-1.
|
|
Brocklebank, V;
Kumar, G;
Howie, AJ;
Chandar, J;
Milford, DV;
Craze, J;
Evans, J;
... Kavanagh, D; + view all
(2020)
Long-term outcomes and response to treatment in diacylglycerol kinase epsilon nephropathy.
Kidney International
, 97
(6)
pp. 1260-1274.
10.1016/j.kint.2020.01.045.
|
|
|
Brooks, Lucy J;
Clements, Melanie P;
Burden, Jemima J;
Kocher, Daniela;
Richards, Luca;
Devesa, Sara Castro;
Zakka, Leila;
... Parrinello, Simona; + view all
(2022)
Author Correction: The white matter is a pro-differentiative niche for glioblastoma.
Nature Communications
, 13
(1)
, Article 2163. 10.1038/s41467-022-29916-y.
|
|
Brooks, LJ;
Clements, MP;
Burden, JJ;
Kocher, D;
Richards, L;
Devesa, SC;
Zakka, L;
... Parrinello, S; + view all
(2021)
The white matter is a pro-differentiative niche for glioblastoma.
Nature Communications
, 12
, Article 2184. 10.1038/s41467-021-22225-w.
|
|
|
Brown, Nicholas F;
Murray, Elizabeth R;
Cutmore, Lauren C;
Howard, Philip;
Masterson, Luke;
Zammarchi, Francesca;
Hartley, John A;
... Marshall, John F; + view all
(2024)
Integrin-αvβ6 targeted peptide-toxin therapy in a novel αvβ6-expressing immunocompetent model of pancreatic cancer.
Pancreatology
10.1016/j.pan.2024.02.013.
(In press).
|
|
Brown, Sarah R;
Hinsley, Samantha;
Hall, Emma;
Hurt, Chris;
Baird, Richard D;
Forster, Martin;
Scarsbrook, Andrew F;
(2022)
A Road Map for Designing Phase I Clinical Trials of Radiotherapy–Novel Agent Combinations.
Clinical Cancer Research
, 28
(17)
pp. 3639-3651.
10.1158/1078-0432.CCR-21-4087.
|
|
Brown, NF;
Williams, M;
Arkenau, H-T;
Fleming, RA;
Tolson, J;
Yan, L;
Zhang, J;
... Mulholland, P; + view all
(2018)
A study of the focal adhesion kinase inhibitor GSK2256098 in patients with recurrent glioblastoma with evaluation of tumor penetration of [¹¹C]GSK2256098.
Neuro-Oncology
, 20
(12)
pp. 1634-1642.
10.1093/neuonc/noy078.
|
|
Buck, M;
Poirier, E;
Cardoso, A;
Frederico, B;
Canton, J;
Barrell, S;
Beale, R;
... The Crick COVID-19 Consortium; + view all
(2021)
SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay [version 1; peer review: 1 approved with reservations].
Wellcome Open Research
, 6
(9)
10.12688/wellcomeopenres.16517.1.
|
|
|
Buck, MD;
Poirier, EZ;
Cardoso, A;
Frederico, B;
Canton, J;
Barrell, S;
Beale, R;
... Crick COVID-19 Consortium; + view all
(2021)
SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay.
Wellcome Open Research
, 6
, Article 9. 10.12688/wellcomeopenres.16517.2.
|
|
|
Budczies, J;
Allgäuer, M;
Litchfield, K;
Rempel, E;
Christopoulos, P;
Kazdal, D;
Endris, V;
... Stenzinger, A; + view all
(2019)
Optimizing panel-based tumor mutational burden (TMB) measurement.
Annals of Oncology
, 30
(9)
pp. 1496-1506.
10.1093/annonc/mdz205.
|
|
|
Burrell, Rebecca A;
McClelland, Sarah E;
Endesfelder, David;
Groth, Petra;
Weller, Marie-Christine;
Shaikh, Nadeem;
Domingo, Enric;
... Swanton, Charles; + view all
(2013)
Replication stress links structural and numerical cancer chromosomal instability.
Nature
, 494
(7438)
pp. 492-496.
10.1038/nature11935.
|
|
|
Busacca, S;
Zhang, Q;
Sharkey, A;
Dawson, AG;
Moore, DA;
Waller, DA;
Nakas, A;
... Fennell, DA; + view all
(2021)
Transcriptional perturbation of protein arginine methyltransferase-5 exhibits MTAP-selective oncosuppression.
Scientific Reports
, 11
(1)
, Article 7434. 10.1038/s41598-021-86834-7.
|
|
|
Butler, CR;
Hynds, RE;
Crowley, C;
Gowers, KH;
Partington, L;
Hamilton, NJ;
Carvalho, C;
... Janes, SM; + view all
(2017)
Vacuum-assisted decellularization: an accelerated protocol to generate tissue-engineered human tracheal scaffolds.
Biomaterials
, 124
pp. 95-105.
10.1016/j.biomaterials.2017.02.001.
|
|
|
Byers, LA;
Navarro, A;
Schaefer, E;
Johnson, M;
Özgüroğlu, M;
Han, J-Y;
Bondarenko, I;
... Forster, M; + view all
(2021)
A Phase II Trial of Prexasertib (LY2606368) in Patients With Extensive-Stage Small-Cell Lung Cancer.
Clinical Lung Cancer
, 22
(6)
pp. 531-540.
10.1016/j.cllc.2021.04.005.
|
|
C
|
Cabrera, R;
Singal, AG;
Colombo, M;
Kelley, RK;
Lee, H;
Mospan, AR;
Meyer, T;
... Di Bisceglie, AM; + view all
(2021)
A Real-World Observational Cohort of Patients with Hepatocellular Carcinoma: Design and Rationale for TARGET-HCC.
Hepatology Communications
, 5
(3)
pp. 538-547.
10.1002/hep4.1652.
|
|
|
Cai, H;
Chew, SK;
Li, C;
Tsai, MK;
Andrejka, L;
Murray, CW;
Hughes, NW;
... Winslow, MM; + view all
(2021)
A Functional Taxonomy of Tumor Suppression in Oncogenic KRAS-Driven Lung Cancer.
Cancer Discovery
, 11
(7)
pp. 1754-1773.
10.1158/2159-8290.CD-20-1325.
|
|
Cailleau, T;
Adams, LR;
Arora, N;
Kang, G-D;
Masterson, L;
Patel, N;
Hartley, JA;
... Howard, PW; + view all
(2019)
Potentiation of PBD Dimers by Lipophilicity Manipulation.
Current Topics in Medicinal Chemistry
, 19
(9)
pp. 741-752.
10.2174/1568026619666190401112517.
|
|
Calvo, E;
Moreno, V;
Flynn, M;
Holgado, E;
Olmedo, ME;
Criado, MPL;
Kahatt, C;
... Forster, M; + view all
(2017)
Antitumor activity of lurbinectedin (PM01183) and doxorubicin in relapsed small-cell lung cancer: results from a phase I study.
Annals of Oncology
, 28
(10)
pp. 2559-2566.
10.1093/annonc/mdx357.
|
|
|
Campbell, Rachel;
Costa, Daniel SJ;
Stockler, Martin R;
Lee, Yeh Chen;
Ledermann, Jonathan A;
Berton, Dominique;
Sehouli, Jalid;
... GCIG Symptom Benefit Group; + view all
(2022)
Measure of Ovarian Symptoms and Treatment concerns (MOST) indexes and their associations with health-related quality of life in recurrent ovarian cancer.
Gynecologic Oncology
, 166
(2)
pp. 254-262.
10.1016/j.ygyno.2022.05.024.
|
|
Campbell, J;
Ryan, CJ;
Brough, R;
Bajrami, I;
Pemberton, HN;
Chong, IY;
Costa-Cabral, S;
... Lord, CJ; + view all
(2016)
Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.
Cell Reports
, 14
(10)
pp. 2490-2501.
10.1016/j.celrep.2016.02.023.
|
|
Caplin, B;
Veighey, K;
Mahenderan, A;
Manook, M;
Henry, J;
Nitsch, D;
Harber, M;
... Veitch, P; + view all
(2013)
Early changes in scores of chronic damage on transplant kidney protocol biopsies reflect donor characteristics, but not future graft function.
Clin Transplant
, 27
(6)
E669-E678.
10.1111/ctr.12251.
|
|
|
Capper, D;
Engel, NW;
Stichel, D;
Lechner, M;
Gloess, S;
Schmid, S;
Koelsche, C;
... Schueller, U; + view all
(2018)
DNA methylation-based reclassification of olfactory neuroblastoma.
Acta Neuropathologica
, 136
(2)
pp. 255-271.
10.1007/s00401-018-1854-7.
|
|
Carmona Echeverria, LM;
Haider, A;
Freeman, A;
Stopka-Farooqui, U;
Rosenfeld, A;
Simpson, BS;
Hu, Y;
... Whitaker, HC; + view all
(2020)
A critical evaluation of visual proportion of Gleason 4 and maximum cancer core length quantified by histopathologists.
Scientific Reports
, 10
, Article 17177. 10.1038/s41598-020-73524-z.
|
|
|
Carter, T;
Mulholland, P;
Chester, K;
(2016)
Antibody-targeted nanoparticles for cancer treatment.
Immunotherapy
, 8
(8)
pp. 941-958.
10.2217/imt.16.11.
|
|
Carter, T;
Shawy, H;
Cohn-Brown, D;
Chester, K;
Mulholland, P;
(2016)
Ipilimumab and Bevacizumab in Glioblastoma.
Clinical Oncology
, 28
(10)
pp. 622-626.
10.1016/j.clon.2016.04.042.
|
|
|
Carter, Thomas James;
(2019)
Magnetic Hyperthermia for the Treatment of Glioblastoma.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Carter, TJ;
Agliardi, G;
Lin, F-Y;
Ellis, M;
Jones, C;
Robson, M;
Richard-Londt, A;
... Chester, K; + view all
(2021)
Potential of Magnetic Hyperthermia to Stimulate Localized Immune Activation.
Small
, Article e2005241. 10.1002/smll.202005241.
(In press).
|
|
|
Carter, TJ;
Milic, M;
McDerra, J;
McTiernan, A;
Ahmed, M;
Karavasilis, V;
Michelagnoli, M;
... Strauss, SJ; + view all
(2020)
Continuous 14 Day Infusional Ifosfamide for Management of Soft-Tissue and Bone Sarcoma: A Single Centre Retrospective Cohort Analysis.
Cancers
, 12
(11)
, Article 3408. 10.3390/cancers12113408.
|
|
|
Casali, PG;
Blay, JY;
Abecassis, N;
Bajpai, J;
Bauer, S;
Biagini, R;
Bielack, S;
... Stacchiotti, S; + view all
(2022)
Gastrointestinal stromal tumours: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Annals of Oncology
, 33
(1)
pp. 20-33.
10.1016/j.annonc.2021.09.005.
|
|
Casali, PG;
Bielack, S;
Abecassis, N;
Aro, HT;
Bauer, S;
Biagini, R;
Bonvalot, S;
... Blay, JY; + view all
(2018)
Bone sarcomas: ESMO–PaedCan–EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Annals of Oncology
, 29
(4)
pp. 79-95.
10.1093/annonc/mdy310.
|
|
|
Casiraghi, N;
Orlando, F;
Ciani, Y;
Xiang, J;
Sboner, A;
Elemento, O;
Attard, G;
... Romanel, A; + view all
(2020)
ABEMUS: platform specific and data informed detection of somatic SNVs in cfDNA.
Bioinformatics
, 36
(9)
pp. 2665-2674.
10.1093/bioinformatics/btaa016.
|
|
Cassoni, A;
Ali, U;
Cave, J;
Edwards, SG;
Ramsay, A;
Miller, RF;
Lee, SM;
(2008)
Remission After Radiotherapy for a Patient With Chemotherapy-Refractory HIV-Associated Primary Effusion Lymphoma.
Journal of Clinical Oncology
, 26
(32)
5297 - 5299.
10.1200/JCO.2008.18.3350.
|
|
|
Castañeda, L;
Maruani, A;
Schumacher, FF;
Miranda, E;
Chudasama, V;
Chester, KA;
Baker, JR;
... Caddick, S; + view all
(2013)
Acid-cleavable thiomaleamic acid linker for homogeneous antibody-drug conjugation.
Chemical Communications
, 49
pp. 8187-8189.
10.1039/c3cc45220d.
|
|
|
Castillo, SD;
Tzouanacou, E;
Zaw-Thin, M;
Berenjeno, IM;
Parker, VE;
Chivite, I;
Milà-Guasch, M;
... Vanhaesebroeck, B; + view all
(2016)
Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans.
Science Translational Medicine
, 8
(332)
, Article 332ra43. 10.1126/scitranslmed.aad9982.
|
|
Castillo, SD;
Vanhaesebroeck, B;
Sebire, NJ;
(2016)
Phosphoinositide 3-kinase: a new kid on the block in vascular anomalies.
The Journal of Pathology
, 240
(4)
pp. 387-396.
10.1002/path.4802.
|
|
Caswell, Deborah R;
Gui, Philippe;
Mayekar, Manasi K;
Law, Emily K;
Pich, Oriol;
Bailey, Chris;
Boumelha, Jesse;
... Swanton, Charles; + view all
(2023)
The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance.
Nature Genetics
10.1038/s41588-023-01592-8.
(In press).
|
|
Caswell, DR;
Swanton, C;
(2017)
The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome.
[Review].
BMC Medicine
, 15
, Article 133. 10.1186/s12916-017-0900-y.
|
|
|
Cerone, Maria Antonietta;
Mills, Tara C;
Sharpe, Rowena;
McBride, David;
MacDonald, Moira;
MacMahon, Suzanne;
Mugalaasi, Hood;
... SMP2, consortium; + view all
(2023)
The Cancer Research UK Stratified Medicine Programme as a model for delivering personalised cancer care.
British Journal of Cancer
10.1038/s41416-022-02107-8.
(In press).
|
|
Chakravarthy, A;
Furness, A;
Joshi, K;
Ghorani, E;
Ford, K;
Ward, MJ;
King, EV;
... Fenton, TR; + view all
(2018)
Author Correction: Pan-cancer deconvolution of tumour composition using DNA methylation.
[Corrigendum].
Nature Communications
, 9
, Article 4642. 10.1038/s41467-018-07155-4.
|
|
|
Chakravarthy, A;
Furness, A;
Joshi, K;
Ghorani, E;
Ford, K;
Ward, MJ;
King, EV;
... Fenton, TR; + view all
(2018)
Pan-cancer deconvolution of tumour composition using DNA methylation.
Nature Communications
, 9
, Article 3220. 10.1038/s41467-018-05570-1.
|
 |
|
Chakravarthy, A;
Henderson, S;
Thirdborough, SM;
Ottensmeier, CH;
Su, X;
Lechner, M;
Feber, A;
... Fenton, TR; + view all
(2016)
Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx.
Journal Of Clinical Oncology
, 34
(34)
pp. 4132-4141.
10.1200/JCO.2016.68.2955.
|
|
|
Chambers, P;
Wei, L;
Forster, MD;
Kipps, E;
Wong, ICK;
Jani, Y;
(2021)
Evidence to guide the optimal timing for pre-chemotherapy blood tests for early breast, colorectal cancer and diffuse large B-cell lymphoma.
Cancer Medicine
10.1002/cam4.4316.
(In press).
|
|
|
Chambers, P;
Jani, Y;
Wei, L;
Kipps, E;
Forster, MD;
Wong, ICK;
(2019)
Patient Factors and their Impact on Neutropenic Events: A Systematic review and meta-analysis.
Supportive Care in Cancer
, 27
(7)
pp. 2413-2424.
10.1007/s00520-019-04773-6.
|
|
Chambers, P;
Man, KKC;
Lui, VWY;
Mpima, S;
Nasuti, P;
Forster, MD;
Wong, ICK;
(2020)
Understanding Molecular Testing Uptake Across Tumor Types in Eight Countries: Results From a Multinational Cross-Sectional Survey.
JCO Precision Oncology
, 16
(8)
e770-e778.
10.1200/JOP.19.00507.
|
|
Chan, TA;
Yarchoan, M;
Jaffee, E;
Swanton, C;
Quezada, SA;
Stenzinger, A;
Peters, S;
(2019)
Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic.
Annals of Oncology
, 30
(1)
pp. 44-56.
10.1093/annonc/mdy495.
|
|
|
Chatterjee, M;
Turner, DC;
Felip, E;
Lena, H;
Cappuzzo, F;
Horn, L;
Garon, EB;
... Flotten, O; + view all
(2016)
Systematic evaluation of pembrolizumab dosing in patients with advanced non-small-cell lung cancer.
Annals of Oncology
, 27
(7)
pp. 1291-1298.
10.1093/annonc/mdw174.
|
|
Chau, I;
Penel, N;
Soriano, AO;
Arkenau, HT;
Cultrera, J;
Santana-Davila, R;
Calvo, E;
... Fuchs, CS; + view all
(2020)
Ramucirumab in combination with pembrolizumab in treatment-naïve advanced gastric or gej adenocarcinoma: Safety and antitumor activity from the phase 1a/b jvdf trial.
Cancers
, 12
(10)
, Article 2985. 10.3390/cancers12102985.
|
|
|
Chemi, F;
Rothwell, DG;
McGranahan, N;
Gulati, S;
Abbosh, C;
Pearce, SP;
Zhou, C;
... TRACERx Consortium, .; + view all
(2019)
Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse.
Nature Medicine
, 25
pp. 1534-1539.
10.1038/s41591-019-0593-1.
|
|
Chen, Kezhong;
Kang, Guannan;
Zhang, Zhihong;
Lizaso, Analyn;
Beck, Stephan;
Lyskjær, Iben;
Chervova, Olga;
... Wang, Jun; + view all
(2023)
Individualized dynamic methylation-based analysis of cell-free DNA in postoperative monitoring of lung cancer.
BMC Medicine
, 21
, Article 255. 10.1186/s12916-023-02954-z.
|
|
Chen, Kezhong;
Yang, Airong;
Carbone, David P;
Kanu, Nnennaya;
Liu, Ke;
Wang, Ruiru;
Nie, Yuntao;
... Wang, Jun; + view all
(2022)
Spatiotemporal genomic analysis reveals distinct molecular features in recurrent stage I non-small cell lung cancers.
Cell Reports
, 40
(2)
, Article 111047. 10.1016/j.celrep.2022.111047.
|
|
Chen, Kezhong;
Yang, Fan;
Shen, Haifeng;
Wang, Chenyang;
Li, Xi;
Chervova, Olga;
Wu, Shuailai;
... Wang, Jun; + view all
(2023)
Individualized tumor-informed circulating tumor DNA analysis for postoperative monitoring of non-small cell lung cancer.
Cancer Cell
, 41
(10)
1749-1762.e6.
10.1016/j.ccell.2023.08.010.
|
|
Chen, M;
Chen, R;
Jin, Y;
Li, J;
Hu, X;
Zhang, J;
Fujimoto, J;
... Zhang, J; + view all
(2021)
Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer.
Nature Communications
, 12
, Article 6655. 10.1038/s41467-021-26821-8.
|
|
Chen, X;
Zhabyeyev, P;
Azad, AK;
Vanhaesebroeck, B;
Grueter, CE;
Murray, AG;
Kassiri, Z;
(2021)
Pharmacological and cell-specific genetic PI3Kα inhibition worsens cardiac remodeling after myocardial infarction.
Journal of Molecular and Cellular Cardiology
, 157
pp. 17-30.
10.1016/j.yjmcc.2021.04.004.
|
|
Chen, L;
Esfandiari, A;
Reaves, W;
Vu, A;
Hogarty, MD;
Lunec, J;
Tweddle, DA;
(2018)
Characterisation of the p53 pathway in cell lines established from TH-MYCN transgenic mouse tumours.
International Journal of Oncology
, 52
(3)
pp. 967-977.
10.3892/ijo.2018.4261.
|
|
Chen, S-H;
Miles, K;
Taylor, SA;
Ganeshan, B;
Rodriquez, M;
Fraioli, F;
Wan, S;
... Groves, A; + view all
(2021)
FDG-PET/CT in colorectal cancer: potential for vascular-metabolic imaging to provide markers of prognosis.
European Journal of Nuclear Medicine and Molecular Imaging
10.1007/s00259-021-05318-y.
(In press).
|
|
|
Chen, X;
Zhabyeyev, P;
Azad, AK;
Wang, W;
Minerath, RA;
DesAulniers, J;
Grueter, CE;
... Oudit, GY; + view all
(2019)
Endothelial and cardiomyocyte PI3Kβ divergently regulate cardiac remodelling in response to ischaemic injury.
Cardiovascular Research
, 115
(8)
pp. 1343-1356.
10.1093/cvr/cvy298.
|
|
Chi, Kim N;
Rathkopf, Dana;
Smith, Matthew R;
Efstathiou, Eleni;
Attard, Gerhardt;
Olmos, David;
Lee, Ji Youl;
... MAGNITUDE Principal Investigators; + view all
(2023)
Niraparib and Abiraterone Acetate for Metastatic Castration-Resistant Prostate Cancer.
Journal of Clinical Oncology
10.1200/JCO.22.01649.
(In press).
|
|
Chi, KN;
Sandhu, S;
Smith, MR;
Attard, G;
Saad, M;
Olmos, D;
Castro, E;
... Efstathiou, E; + view all
(2023)
Niraparib plus abiraterone acetate with prednisone in patients with metastatic castration-resistant prostate cancer and homologous recombination repair gene alterations: second interim analysis of the randomized phase III MAGNITUDE trial.
Annals of Oncology
10.1016/j.annonc.2023.06.009.
(In press).
|
|
Childs, A;
Zakeri, N;
Ma, YT;
O’Rourke, J;
Ross, P;
Hashem, E;
Hubner, RA;
... Meyer, T; + view all
(2021)
Biopsy for advanced hepatocellular carcinoma: results of a multicentre UK audit.
British Journal of Cancer
10.1038/s41416-021-01535-2.
(In press).
|
|
|
Childs, A;
Kirkwood, A;
Edeline, J;
Tu, VL;
Watkins, J;
Lamarca, A;
Alrifai, D;
... Meyer, T; + view all
(2016)
Ki-67 index and response to chemotherapy in patients with neuroendocrine tumours.
Endocrine-Related Cancer
, 23
(7)
pp. 563-570.
10.1530/ERC-16-0099.
|
|
|
Childs, A;
Steele, CD;
Vesely, C;
Rizzo, FMM;
Ensell, L;
Lowe, H;
Dhami, P;
... Meyer, T; + view all
(2021)
Whole genome sequencing of single circulating tumor cells from neuroendocrine neoplasms.
Endocrine-Related Cancer
10.1530/ERC-21-0179.
(In press).
|
|
|
Childs, A;
Vesely, C;
Ensell, L;
Lowe, H;
Luong, TV;
Caplin, ME;
Toumpanakis, C;
... Meyer, T; + view all
(2016)
Expression of somatostatin receptors 2 and 5 in circulating tumour cells from patients with neuroendocrine tumours.
British Journal of Cancer
, 115
(12)
pp. 1540-1547.
10.1038/bjc.2016.377.
|
|
|
Cho, S;
Zammarchi, F;
Williams, DG;
Havenith, CE;
Monks, NR;
Tyrer, P;
d'Hooge, F;
... van Berkel, PH; + view all
(2018)
Antitumor Activity of MEDI3726 (ADCT-401), a Pyrrolobenzodiazepine Antibody-drug Conjugate Targeting PSMA, in Pre-clinical Models of Prostate Cancer.
Molecular Cancer Therapeutics
, 17
(10)
10.1158/1535-7163.MCT-17-0982.
|
|
Choueiri, TK;
Plimack, E;
Arkenau, H-T;
Jonasch, E;
Heng, DYC;
Powles, T;
Frigault, MM;
... Pal, SK; + view all
(2017)
Biomarker-Based Phase II Trial of Savolitinib in Patients With Advanced Papillary Renal Cell Cancer.
Journal of Clinical Oncology
, 35
(26)
pp. 2993-3001.
10.1200/JCO.2017.72.2967.
|
|
|
Chowdhury, T.;
(2007)
Investigation of the role of MLL-ENL in leukaemogenesis.
Doctoral thesis , University of London.
|
|
|
Christensen, Ditte S;
Ahrenfeldt, Johanne;
Sokac, Mateo;
Kisistok, Judit;
Thomsen, Martin K;
Maretty, Lasse;
McGranahan, Nicholas;
(2022)
Treatment Represents a Key Driver of Metastatic Cancer Evolution.
Cancer Research
, 82
(16)
pp. 2918-2927.
10.1158/0008-5472.CAN-22-0562.
|
|
Chugh, R;
Ballman, KV;
Helman, LJ;
Patel, S;
Whelan, JS;
Widemann, B;
Lu, Y;
... Strauss, SJ; + view all
(2020)
SARC025 arms 1 and 2: A phase 1 study of the poly(ADP‐ribose) polymerase inhibitor niraparib with temozolomide or irinotecan in patients with advanced Ewing sarcoma.
Cancer
10.1002/cncr.33349.
|
|
|
Chung, C-Y;
Singh, K;
Kotiadis, VN;
Valdebenito, GE;
Ahn, JH;
Topley, E;
Tan, J;
... Duchen, MR; + view all
(2021)
Constitutive activation of the PI3K-Akt-mTORC1 pathway sustains the m.3243 A > G mtDNA mutation.
Nature Communications
, 12
(1)
, Article 6409. 10.1038/s41467-021-26746-2.
|
|
|
Chung, HC;
Arkenau, H-T;
Lee, J;
Rha, SY;
Oh, D-Y;
Wyrwicz, L;
Kang, Y-K;
... Safran, H; + view all
(2019)
Avelumab (anti-PD-L1) as first-line switch-maintenance or second-line therapy in patients with advanced gastric or gastroesophageal junction cancer: phase 1b results from the JAVELIN Solid Tumor trial.
Journal for ImmunoTherapy of Cancer
, 7
, Article 30. 10.1186/s40425-019-0508-1.
|
|
|
Chung, R;
Maulik, A;
Hamarneh, A;
Hochhauser, D;
Hausenloy, DJ;
Walker, JM;
Yellon, DM;
(2016)
Effect of Remote Ischaemic Conditioning in ONCology patients undergoing chemotherapy: rationale and design of the ERIC-ONC study - a single-center, blinded, randomized controlled trial.
Clinical Cardiology
, 39
(2)
pp. 72-82.
10.1002/clc.22507.
|
|
|
Clarke, NW;
Ali, A;
Ingleby, FC;
Hoyle, A;
Amos, CL;
Attard, G;
Brawley, CD;
... STAMPEDE investigators; + view all
(2020)
Corrigendum to Addition of docetaxel to hormonal therapy in low- and high-burden metastatic hormone sensitive prostate cancer: long-term survival results from the STAMPEDE trial: Ann Oncol 2019; 30: 1992-2003.
[Corrigendum].
Annals of Oncology
, 31
(3)
p. 442.
10.1016/j.annonc.2020.01.002.
|
|
|
Clarke, NW;
Ali, A;
Ingleby, FC;
Hoyle, A;
Amos, CL;
Attard, G;
Brawley, CD;
... James, ND; + view all
(2019)
Addition of docetaxel to hormonal therapy in low- and high-burden metastatic hormone sensitive prostate cancer: long-term survival results from the STAMPEDE trial.
Annals of Oncology
10.1093/annonc/mdz396.
(In press).
|
|
Claus, J;
Patel, G;
Autore, F;
Colomba, A;
Weitsman, G;
Soliman, TN;
Roberts, S;
... Parker, PJ; + view all
(2018)
Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface.
eLIFE
, 7
, Article e32271. 10.7554/eLife.32271.
|
|
|
Clements, MP;
Byrne, E;
Camarillo Guerrero, LF;
Cattin, A-L;
Zakka, L;
Ashraf, A;
Burden, JJ;
... Parrinello, S; + view all
(2017)
The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration.
Neuron
, 96
(1)
98-114.e7.
10.1016/j.neuron.2017.09.008.
|
|
|
Collier, DA;
De Marco, A;
Ferreira, IATM;
Meng, B;
Datir, RP;
Walls, AC;
Kemp, SA;
... Gupta, RK; + view all
(2021)
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies.
Nature
, 593
pp. 136-141.
10.1038/s41586-021-03412-7.
|
|
Colomba, A;
Fitzek, M;
George, R;
Weitsman, G;
Roberts, S;
Zanetti-Domingues, L;
Hirsch, M;
... Parker, PJ; + view all
(2020)
A small molecule inhibitor of HER3: a proof-of-concept study.
Biochemical Journal
, 477
(17)
pp. 3329-3347.
10.1042/BCJ20200496.
|
|
|
Conduit, SE;
Davies, EM;
Ooms, LM;
Gurung, R;
McGrath, MJ;
Hakim, S;
Cottle, DL;
... Mitchell, CA; + view all
(2020)
AKT signaling promotes DNA damage accumulation and proliferation in polycystic kidney disease.
Human Molecular Genetics
, 29
(1)
pp. 31-48.
10.1093/hmg/ddz232.
|
|
Conduit, SE;
Vanhaesebroeck, B;
(2020)
Phosphoinositide lipids in primary cilia biology.
Biochemical Journal
, 477
(18)
pp. 3541-3565.
10.1042/BCJ20200277.
|
|
|
Conforti, F;
Pala, L;
Pagan, E;
Bagnardi, V;
De Pas, T;
Queirolo, P;
Pennacchioli, E;
... Giaccone, G; + view all
(2021)
Sex-Based Dimorphism of Anticancer Immune Response and Molecular Mechanisms of Immune Evasion.
Clinical Cancer Research
, 27
(15)
pp. 4311-4324.
10.1158/1078-0432.CCR-21-0136.
|
|
Conibear, J;
Chia, B;
Ngai, Y;
Bates, AT;
Counsell, N;
Patel, R;
Eaton, D;
... Landau, D; + view all
(2018)
Study protocol for the SARON trial: a multicentre, randomised controlled phase III trial comparing the addition of stereotactic ablative radiotherapy and radical radiotherapy with standard chemotherapy alone for oligometastatic non-small cell lung cancer.
BMJ Open
, 8
(4)
, Article e020690. 10.1136/bmjopen-2017-020690.
|
|
|
Conteduca, V;
Jayaram, A;
Romero-Laorden, N;
Wetterskog, D;
Salvi, S;
Gurioli, G;
Scarpi, E;
... de Giorgi, U; + view all
(2019)
Plasma Androgen Receptor and Docetaxel for Metastatic Castration-resistant Prostate Cancer.
European Urology
10.1016/j.eururo.2018.09.049.
(In press).
|
|
|
Conteduca, V;
Scarpi, E;
Salvi, S;
Casadio, V;
Lolli, C;
Gurioli, G;
Schepisi, G;
... De Giorgi, U; + view all
(2018)
Plasma Androgen Receptor and Serum Chromogranin a in Advanced Prostate Cancer.
Scientific Reports
, 8
, Article 15442. 10.1038/s41598-018-33774-4.
|
|
|
Conteduca, V;
Wetterskog, D;
Sharabiani, MTA;
Grande, E;
Fernandez-Perez, MP;
Jayaram, A;
Salvi, S;
... Spanish Oncology Genitourinary Group, .; + view all
(2017)
Androgen receptor gene status in plasma DNA associates with worse outcome on enzalutamide or abiraterone for castration-resistant prostate cancer: a multi-institution correlative biomarker study.
Annals of Oncology
, 28
(7)
pp. 1508-1516.
10.1093/annonc/mdx155.
|
|
Cook, R;
Zoumpoulidou, G;
Luczynski, MT;
Rieger, S;
Moquet, J;
Spanswick, VJ;
Hartley, JA;
... Mittnacht, S; + view all
(2015)
Direct Involvement of Retinoblastoma Family Proteins in DNA Repair by Non-homologous End-Joining.
Cell Rep
, 10
(12)
2006 - 2018.
10.1016/j.celrep.2015.02.059.
|
|
|
Coombes, C;
Page, K;
Salari, R;
Hastings, RK;
Armstrong, AC;
Ahmed, S;
Ali, S;
... Shaw, JA; + view all
(2019)
Personalized detection of circulating tumor DNA antedates breast cancer metastatic recurrence.
Clinical Cancer Research
, 25
(14)
pp. 4255-4263.
10.1158/1078-0432.CCR-18-3663.
|
|
Cope, AP;
Barnes, MR;
Belson, A;
Binks, M;
Brockbank, S;
Bonachela-Capdevila, F;
Carini, C;
... RA-MAP Consortium; + view all
(2018)
The RA-MAP Consortium: a working model for academia-industry collaboration.
Nature Reviews Rheumatology
, 14
(1)
pp. 53-60.
10.1038/nrrheum.2017.200.
|
|
Corbett, S;
Huang, S;
Zammarchi, F;
Howard, PW;
van Berkel, PH;
Hartley, JA;
(2020)
The Role of Specific ATP-Binding Cassette Transporters in the Acquired Resistance to Pyrrolobenzodiazepine Dimer-Containing Antibody-Drug Conjugates.
Molecular Cancer Therapeutics
, 19
(9)
pp. 1856-1865.
10.1158/1535-7163.MCT-20-0222.
|
|
Corroyer-Dulmont, A;
Falzone, N;
Kersemans, V;
Thompson, J;
Allen, DP;
Able, S;
Kartsonaki, C;
... Vallis, KA; + view all
(2017)
Improved outcome of 131I-mIBG treatment through combination with
external beam radiotherapy in the SK-N-SH mouse model of
neuroblastoma.
Radiotherapy and Oncology
, 124
(3)
pp. 488-495.
10.1016/j.radonc.2017.05.002.
|
|
|
Corroyer-Dulmont, A;
Falzone, N;
Kersemans, V;
Thompson, J;
Hill, M;
Danny Allen, P;
Beech, J;
... Vallis, KA; + view all
(2017)
MRI-guided radiotherapy of the SK-N-SH neuroblastoma xenograft model using a small animal radiation research platform.
British Journal of Radiology
, 90
(1069)
, Article 20160427. 10.1259/bjr.20160427.
|
|
|
Cortellini, A;
De Giglio, A;
Cannita, K;
Cortinovis, DL;
Cornelissen, R;
Baldessari, C;
Giusti, R;
... Porzio, G; + view all
(2021)
Smoking status during first-line immunotherapy and chemotherapy in NSCLC patients: A case–control matched analysis from a large multicenter study.
Thoracic Cancer
, 12
(6)
pp. 880-889.
10.1111/1759-7714.13852.
|
|
Cortellini, Alessio;
Aguilar-Company, Juan;
Salazar, Ramon;
Bower, Mark;
Sita-Lumsden, Ailsa;
Plaja, Andrea;
Lee, Alvin JX;
... Pinato, David J; + view all
(2022)
Natural immunity to SARS-CoV-2 and breakthrough infections in vaccinated and unvaccinated patients with cancer.
British Journal of Cancer
10.1038/s41416-022-01952-x.
(In press).
|
|
Cortellini, Alessio;
Gennari, Alessandra;
Pommeret, Fanny;
Patel, Grisma;
Newsom-Davis, Thomas;
Bertuzzi, Alexia;
Viladot, Margarita;
... OnCovid study group, .; + view all
(2022)
COVID-19 Sequelae and the Host Pro-Inflammatory Response: An Analysis From the OnCovid Registry.
JNCI: Journal of the National Cancer Institute
, 114
(7)
pp. 979-987.
10.1093/jnci/djac057.
|
|
Cortellini, Alessio;
Salazar, Ramon;
Gennari, Alessandra;
Aguilar-Company, Juan;
Bower, Mark;
Bertuzzi, Alexia;
Brunet, Joan;
... Pinato, David J; + view all
(2022)
Persistence of long-term COVID-19 sequelae in patients with cancer: an analysis from the OnCovid registry.
European Journal of Cancer
, 170
pp. 10-16.
10.1016/j.ejca.2022.03.019.
|
|
Cottone, Lucia;
Ligammari, Lorena;
Lee, Hang-Mao;
Knowles, Helen J;
Henderson, Stephen;
Bianco, Sara;
Davies, Christopher;
... Flanagan, Adrienne M; + view all
(2022)
Aberrant paracrine signalling for bone remodelling underlies the mutant histone-driven giant cell tumour of bone.
Cell Death & Differentiation
, 29
pp. 2459-2471.
10.1038/s41418-022-01031-x.
|
|
Coulter, TI;
Chandra, A;
Bacon, CM;
Babar, J;
Curtis, J;
Screaton, N;
Goodlad, JR;
... Cant, AJ; + view all
(2016)
Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study.
J Allergy Clin Immunol
10.1016/j.jaci.2016.06.021.
|
|
|
Courreges, Christina JF;
Davenport, Elizabeth CM;
Bilanges, Benoit;
Rebollo-Gomez, Elena;
Hukelmann, Jens;
Schoenfelder, Priya;
Edgar, James R;
... Okkenhaug, Klaus; + view all
(2024)
Lack of phosphatidylinositol 3-kinase VPS34 in regulatory T cells leads to a fatal lymphoproliferative disorder without affecting their development.
Frontiers in Immunology
, 15
, Article 1374621. 10.3389/fimmu.2024.1374621.
|
|
|
Craig, Z;
Swain, J;
Batman, E;
Wadsley, J;
Reed, N;
Faluyi, O;
Cave, J;
... McNamara, MG; + view all
(2020)
NET-02 trial protocol: a multicentre, randomised, parallel group, open-label, phase II, single-stage selection trial of liposomal irinotecan (nal-IRI) and 5-fluorouracil (5-FU)/folinic acid or docetaxel as second-line therapy in patients with progressive poorly differentiated extrapulmonary neuroendocrine carcinoma (NEC).
BMJ Open
, 10
(2)
, Article e034527. 10.1136/bmjopen-2019-034527.
|
|
|
Crockford, A;
Zalmas, LP;
Grönroos, E;
Dewhurst, SM;
McGranahan, N;
Cuomo, ME;
Encheva, V;
... Swanton, C; + view all
(2017)
Cyclin D mediates tolerance of genome-doubling in cancers with functional p53.
Annals of Oncology
, 28
(1)
pp. 149-156.
10.1093/annonc/mdw612.
|
|
|
Crockford, AJ;
(2016)
Deciphering tetraploid tolerance.
Doctoral thesis , UCL (University College London).
|
|
|
Crolley, Valerie;
Bridgewater, John;
(2024)
Futibatinib for the Treatment of Previously Treated, Unresectable, Locally Advanced or Metastatic Intrahepatic Cholangiocarcinoma with Fibroblast Growth Factor Receptor 2 (FGFR2) Gene Fusions or Other Rearrangements.
touchREVIEWS in Oncology & Haematology
, 20
(1)
pp. 12-19.
|
|
|
Crolley, Valerie Elizabeth;
(2025)
Exploring the links between genomic alterations and patient outcomes in biliary tract cancer.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Crolley, VE;
Gibbins, N;
(2017)
One hundred years of external approach medialisation thyroplasty.
Journal of Laryngology and Otology
, 131
(3)
pp. 202-208.
10.1017/S0022215116010033.
|
|
|
Crolley, VE;
Hanna, D;
Joharatnam-Hogan, N;
Chopra, N;
Bamac, E;
Desai, M;
Lam, YC;
... Khan, K; + view all
(2020)
COVID-19 in cancer patients on systemic anti-cancer therapies: outcomes from the CAPITOL (COVID-19 Cancer PatIenT Outcomes in North London) cohort study.
Therapeutic Advances in Medical Oncology
, 12
pp. 1-14.
10.1177/1758835920971147.
|
|
|
Crolley, VE;
Marashi, H;
Rawther, S;
Sirohi, B;
Parton, M;
Graham, J;
Vinayan, A;
... King, J; + view all
(2020)
The impact of Oncotype DX breast cancer assay results on clinical practice: a UK experience.
Breast Cancer Research and Treatment
, 180
pp. 809-817.
10.1007/s10549-020-05578-6.
|
|
|
Crowley, C;
Butler, C;
Camilli, C;
Hynds, R;
Kolluri, KK;
Janes, SM;
De Coppi, P;
(2019)
Non-invasive longitudinal bioluminescence imaging of human mesoangioblasts in bioengineered esophagi.
Tissue Engineering Part C: Methods
, 25
(2)
pp. 103-113.
10.1089/ten.TEC.2018.0351.
|
|
|
Crowley, C;
Klanrit, P;
Butler, CR;
Varanou, A;
Platé, M;
Hynds, RE;
Chambers, RC;
... Janes, SM; + view all
(2016)
Surface modification of a POSS-nanocomposite material to enhance cellular integration of a synthetic bioscaffold.
Biomaterials
, 83
pp. 283-293.
10.1016/j.biomaterials.2016.01.005.
|
|
D
|
Dale, Katie L;
Armond, Jonathan W;
Hynds, Robert E;
Vladimirou, Elina;
(2022)
Modest increase of KIF11 exposes fragilities in the mitotic spindle causing chromosomal instability.
Journal of Cell Science
, 135
(17)
, Article jcs.260031. 10.1242/jcs.260031.
|
|
Davda, R;
(2018)
Wnt signalling in prostate cancer stem-like cells.
Doctoral thesis (M.D(Res)), UCL (University College London).
|
|
|
Davidson, B;
Gurusamy, K;
Corrigan, N;
Croft, J;
Ruddock, S;
Pullan, A;
Brown, J;
... de Wilt, JH; + view all
(2020)
Liver resection surgery compared with thermal ablation in high surgical risk patients with colorectal liver metastases: the LAVA international RCT.
Health Technology Assessment
, 24
(21)
10.3310/hta24210.
|
|
|
Davidson, SM;
Riquelme, JA;
Takov, K;
Vicencio, JM;
Boi-Doku, C;
Khoo, V;
Doreth, C;
... Yellon, DM; + view all
(2017)
Cardioprotection mediated by exosomes is impaired in the setting of type II diabetes but can be rescued by the use of non-diabetic exosomes in vitro.
Journal of Cellular and Molecular Medicine
10.1111/jcmm.13302.
(In press).
|
|
|
Davidson, SM;
Riquelme, JA;
Zheng, Y;
Vicencio, JM;
Lavandero, S;
Yellon, DM;
(2018)
Endothelial cells release cardioprotective exosomes that may contribute to ischaemic preconditioning.
Scientific Reports
, 8
, Article 15885. 10.1038/s41598-018-34357-z.
|
|
|
Davis, LauraMay;
Smith, April-Louise;
Aldridge, Matthew D;
Foulkes, Jack;
Peet, Connie;
Wan, Simon;
Gains, Jennifer E;
... Gaze, Mark N; + view all
(2020)
Personalisation of Molecular Radiotherapy through Optimisation of Theragnostics.
Journal of Personalized Medicine
, 10
(4)
, Article 174. 10.3390/jpm10040174.
|
|
Davis, LM;
Elmaraghi, C;
Buscombe, JR;
Gaze, MN;
(2023)
Clinical perspectives on dosimetry in molecular radiotherapy.
Physica Medica
, 114
, Article 103154. 10.1016/j.ejmp.2023.103154.
|
|
de Bono, JS;
Concin, N;
Hong, DS;
Thistlethwaite, FC;
Machiels, J-P;
Arkenau, H-T;
Plummer, R;
... Lassen, U; + view all
(2019)
Tisotumab vedotin in patients with advanced or metastatic solid tumours (InnovaTV 201): a first-in-human, multicentre, phase 1-2 trial.
Lancet Oncology
, 20
(3)
pp. 383-393.
10.1016/S1470-2045(18)30859-3.
|
|
de Carcer, G;
Venkateswaran, SV;
Salgueiro, L;
El Bakkali, A;
Somogyi, K;
Rowald, K;
Montanes, P;
... Sotillo, R; + view all
(2018)
Plk1 overexpression induces chromosomal instability and suppresses tumor development.
Nature Communications
, 9
, Article 3012. 10.1038/s41467-018-05429-5.
|
|
|
de Greef, PC;
Oakes, T;
Gerritsen, B;
Ismail, M;
Heather, JM;
Hermsen, R;
Chain, B;
(2020)
The naive T-cell receptor repertoire has an extremely broad distribution of clone sizes.
eLife
, 9
, Article e49900. 10.7554/eLife.49900.
|
|
|
De Noon, Solange;
Piggott, Robert;
Trotman, Jamie;
Tadross, John A;
Fittall, Matthew;
Hughes, Debbie;
Ye, Hongtao;
... Flanagan, Adrienne M; + view all
(2023)
Recurrent FOSL1 rearrangements in desmoplastic fibroblastoma.
The Journal of Pathology
, 259
(2)
pp. 119-124.
10.1002/path.6038.
|
|
de Silva, TI;
Liu, G;
Lindsey, BB;
Dong, D;
Moore, SC;
Hsu, NS;
Shah, D;
... Dong, T; + view all
(2021)
The impact of viral mutations on recognition by SARS-CoV-2 specific T cells.
iScience
, 24
(11)
, Article 103353. 10.1016/j.isci.2021.103353.
|
|
|
DeGregori, James;
Pharoah, Paul;
Sasieni, Peter;
Swanton, Charles;
(2020)
Cancer Screening, Surrogates of Survival, and the Soma.
Cancer Cell
, 38
(4)
pp. 433-437.
10.1016/j.ccell.2020.09.003.
|
|
Dejima, Hitoshi;
Hu, Xin;
Chen, Runzhe;
Zhang, Jiexin;
Fujimoto, Junya;
Parra, Edwin R;
Haymaker, Cara;
... Zhang, Jianjun; + view all
(2021)
Immune evolution from preneoplasia to invasive lung adenocarcinomas and underlying molecular features.
Nature Communications
, 12
(1)
, Article 2722. 10.1038/s41467-021-22890-x.
|
|
Deng, Jinhai;
Pan, Teng;
Liu, Zaoqu;
McCarthy, Caitlin;
Vicencio, Jose M;
Cao, Lulu;
Alfano, Giovanna;
... Ng, Tony; + view all
(2023)
The role of TXNIP in cancer: a fine balance between redox, metabolic, and immunological tumor control.
British Journal of Cancer
10.1038/s41416-023-02442-4.
(In press).
|
|
|
Dentro, SC;
Leshchiner, I;
Haase, K;
Tarabichi, M;
Wintersinger, J;
Deshwar, AG;
Yu, K;
... PCAWG Evolution and Heterogeneity Working Group and the PCAWG Co, .; + view all
(2021)
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes.
Cell
, 184
(8)
pp. 2239-2254.
10.1016/j.cell.2021.03.009.
|
|
|
Desai, R;
East, DA;
Hardy, L;
Faccenda, D;
Rigon, M;
Crosby, J;
Alvarez, MS;
... Campanella, M; + view all
(2020)
Mitochondria form contact sites with the nucleus to couple prosurvival retrograde response.
Science Advances
, 6
(51)
, Article eabc9955. 10.1126/sciadv.abc9955.
|
|
|
Dettorre, GM;
Dolly, S;
Loizidou, A;
Chester, J;
Jackson, A;
Mukherjee, U;
Zambelli, A;
... OnCovid study group; + view all
(2021)
Systemic pro-inflammatory response identifies patients with cancer with adverse outcomes from SARS-CoV-2 infection: the OnCovid Inflammatory Score.
Journal for ImmunoTherapy of Cancer
, 9
(3)
, Article e002277. 10.1136/jitc-2020-002277.
|
|
|
Dewhurst, SM;
(2015)
Whole genome doubling propagates chromosomal instability and accelerates cancer genome evolution.
Doctoral thesis , UCL (University College London).
|
|
|
Dhami, P;
Bruce, AW;
Jim, JH;
Dillon, SC;
Hall, A;
Cooper, JL;
Bonhoure, N;
... Vetrie, D; + view all
(2010)
Genomic Approaches Uncover Increasing Complexities in the Regulatory Landscape at the Human SCL (TAL1) Locus.
PLOS ONE
, 5
(2)
, Article e9059. 10.1371/journal.pone.0009059.
|
|
|
Dhami, P;
Saffrey, P;
Bruce, AW;
Dillon, SC;
Chiang, K;
Bonhoure, N;
Koch, CM;
... Vetrie, D; + view all
(2010)
Complex Exon-Intron Marking by Histone Modifications Is Not Determined Solely by Nucleosome Distribution.
PLOS ONE
, 5
(8)
, Article e12339. 10.1371/journal.pone.0012339.
|
|
|
Di Pilato, Mauro;
Gao, Yun;
Sun, Yi;
Fu, Amina;
Grass, Carina;
Seeholzer, Thomas;
Feederle, Regina;
... Keller, Peter; + view all
(2023)
Translational Studies Using the MALT1 Inhibitor (S)-Mepazine to Induce Treg Fragility and Potentiate Immune Checkpoint Therapy in Cancer.
Journal of Immunotherapy and Precision Oncology
, 6
(2)
pp. 61-73.
10.36401/JIPO-22-18.
|
|
|
Diamond, JR;
Goff, B;
Forster, MD;
Bendell, JC;
Britten, CD;
Gordon, MS;
Gabra, H;
... Moore, KM; + view all
(2017)
Phase Ib study of the mitochondrial inhibitor ME-344 plus topotecan in patients with previously treated, locally advanced or metastatic small cell lung, ovarian and cervical cancers.
Investigational New Drugs
, 35
(5)
pp. 627-633.
10.1007/s10637-017-0444-1.
|
|
Dietzen, Michelle;
Zhai, Haoran;
Lucas, Olivia;
Pich, Oriol;
Barrington, Christopher;
Lu, Wei-Ting;
Ward, Sophia;
... Kanu, Nnennaya; + view all
(2024)
Replication timing alterations are associated with mutation acquisition during breast and lung cancer evolution.
Nature Communications
, 15
(1)
, Article 6039. 10.1038/s41467-024-50107-4.
|
|
|
Dikaios, N;
Atkinson, D;
Tudisca, C;
Purpura, P;
Forster, M;
Ahmed, H;
Beale, T;
... Punwani, S; + view all
(2017)
A comparison of Bayesian and non-linear regression methods for robust estimation of pharmacokinetics in DCE-MRI and how it affects cancer diagnosis.
Computerized Medical Imaging and Graphics
, 56
pp. 1-10.
10.1016/j.compmedimag.2017.01.003.
|
|
Dikaios, N;
Punwani, S;
Hamy, V;
Purpura, P;
Rice, S;
Forster, M;
Mendes, R;
... Atkinson, D; + view all
(2013)
Noise Estimation from Averaged Diffusion Weighted Images: Can Unbiased Quantitative Decay Parameters Assist Cancer Evaluation?
Magnetic Resonance in Medicine
, 71
(6)
pp. 2105-2117.
10.1002/mrm.24877.
|
|
|
Dillon, Magnus T;
Guevara, Jeane;
Mohammed, Kabir;
Patin, Emmanuel C;
Smith, Simon A;
Dean, Emma;
Jones, Gemma N;
... Harrington, Kevin J; + view all
(2024)
Durable responses to ATR inhibition with ceralasertib in tumors with genomic defects and high inflammation.
Journal of Clinical Investigation
, 134
(2)
, Article e175369. 10.1172/JCI175369.
|
|
Dillon, M;
Ellis, S;
Grove, L;
McLellan, L;
Clack, G;
Smith, S;
Laude, J;
... Harrington, K; + view all
(2016)
PATRIOT: A phase I study to assess the tolerability, safety and biological effects of a specific ataxia telangiectasia and Rad3-related (ATR) inhibitor (AZD6738) as a single agent and in combination with palliative radiation therapy in patients with solid tumours.
Presented at: ASCO 2016 Annual Meeting: Poster Session, Developmental Therapeutics - Clinical Pharmacology and Experimental Therapeutics, Chicago.
|
|
Dillon, MT;
Boylan, Z;
Smith, D;
Guevara, J;
Mohammed, K;
Peckitt, C;
Saunders, M;
... Harrington, KJ; + view all
(2018)
PATRIOT: A phase I study to assess the tolerability, safety and biological effects of a specific ataxia telangiectasia and Rad3-related (ATR) inhibitor (AZD6738) as a single agent and in combination with palliative radiation therapy in patients with solid tumours.
Clinical and Translational Radiation Oncology
, 12
pp. 16-20.
10.1016/j.ctro.2018.06.001.
|
|
|
Dillon, MT;
Espinasse, A;
Ellis, S;
Mohammed, K;
Grove, LG;
McLellan, L;
Smith, SA;
... Harrington, KJ; + view all
(2017)
A Phase I dose-escalation study of ATR inhibitor monotherapy with AZD6738 in advanced solid tumors (PATRIOT Part A).
Presented at: Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC.
|
|
|
Dillon, MT;
Grove, L;
Newbold, KL;
Shaw, H;
Brown, NF;
Mendell, J;
Chen, S;
... Harrington, KJ; + view all
(2019)
Patritumab with Cetuximab plus Platinum-Containing Therapy in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck: An Open-Label, Phase Ib Study.
Clinical Cancer Research
, 25
(2)
pp. 487-495.
10.1158/1078-0432.CCR-18-1539.
|
|
Ding, H;
Velasco, C;
Ye, H;
Lindner, T;
Grech-Sollars, M;
O'Callaghan, J;
Hiley, C;
... Adeleke, S; + view all
(2021)
Current Applications and Future Development of Magnetic Resonance Fingerprinting in Diagnosis, Characterization, and Response Monitoring in Cancer.
Cancers
, 13
(19)
, Article 4742. 10.3390/cancers13194742.
|
|
|
Dinneen, E;
Allen, C;
Strange, T;
Heffernan-Ho, D;
Banjeglav, J;
Lindsay, J;
Mulligan, JP;
... Punwani, S; + view all
(2022)
Negative mpMRI Rules Out Extra-Prostatic Extension in Prostate Cancer before Robot-Assisted Radical Prostatectomy.
Diagnostics
, 12
(5)
, Article 1057. 10.3390/diagnostics12051057.
|
|
Diocou, S;
Volpe, A;
Jauregui-Osoro, M;
Boudjemeline, M;
Chuamsaamarkkee, K;
Man, F;
Blower, PJ;
... Fruhwirth, GO; + view all
(2017)
[(18)F]tetrafluoroborate-PET/CT enables sensitive tumor and metastasis in vivo imaging in a sodium iodide symporter-expressing tumor model.
Scientific Reports
, 7
, Article 946. 10.1038/s41598-017-01044-4.
|
|
|
Dirix, L;
Swaisland, H;
Verheul, HMW;
Rottey, S;
Leunen, K;
Jerusalem, G;
Rolfo, C;
... Plummer, R; + view all
(2016)
Effect of Itraconazole and Rifampin on the Pharmacokinetics of Olaparib in Patients With Advanced Solid Tumors: Results of Two Phase I Open-label Studies.
Clinical Therapeutics
, 38
(10)
pp. 2286-2299.
10.1016/j.clinthera.2016.08.010.
|
|
Dirix, LY;
Takacs, I;
Jerusalem, G;
Nikolinakos, P;
Arkenau, H-T;
Forero-Torres, A;
Boccia, R;
... Hamilton, EP; + view all
(2018)
Avelumab, an anti-PD-L1 antibody, in patients with locally advanced or metastatic breast cancer: a phase 1b JAVELIN Solid Tumor study.
Breast Cancer Research and Treatment
, 167
(3)
pp. 671-686.
10.1007/s10549-017-4537-5.
|
|
|
Domingues, PH;
Nanduri, LSY;
Seget, K;
Venkateswaran, SV;
Agorku, D;
Vigano, C;
von Schubert, C;
... Hardt, O; + view all
(2017)
Cellular Prion Protein PrPC and Ecto-5′-Nucleotidase Are Markers of the Cellular Stress Response to Aneuploidy.
Cancer Research
, 77
(11)
pp. 2914-2926.
10.1158/0008-5472.CAN-16-3052.
|
|
|
Dong, Lijun;
Han, Haote;
Huang, Xionggao;
Ma, Gaoen;
Fang, Dong;
Qi, Hui;
Han, Zhuo;
... Lei, Hetian; + view all
(2022)
Idelalisib inhibits experimental proliferative vitroretinopathy.
Laboratory Investigation
, 102
(12)
pp. 1296-1303.
10.1038/s41374-022-00822-7.
|
|
Dowgier, G;
Hobbs, A;
Greenwood, D;
Shawe-Taylor, M;
Stevenson-Leggett, P;
Bazire, J;
Penn, R;
... Wu, MY; + view all
(2025)
Accurate evaluation of live-virus microneutralisation for SARS-CoV-2 variant JN.1 in the assessment of vaccination and therapeutics.
Vaccine
, 54
, Article 126960. 10.1016/j.vaccine.2025.126960.
|
|
|
Drew, Y;
Kristeleit, RS;
Oaknin, A;
Ray-Coquard, I;
Haris, NM;
Swisher, EM;
(2020)
Real-World Delivery of Rucaparib to Patients with Ovarian Cancer: Recommendations Based on an Integrated Safety Analysis of ARIEL2 and Study 10.
The Oncologist
, 25
(1)
e109-e119.
10.1634/theoncologist.2019-0229.
|
|
|
Drilon, A;
Siena, S;
Dziadziuszko, R;
Barlesi, F;
Krebs, MG;
Shaw, AT;
de Braud, F;
... Doebele, RC; + view all
(2020)
Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1-2 trials.
The Lancet Oncology
, 21
(2)
pp. 261-270.
10.1016/S1470-2045(19)30690-4.
|
|
Drummond, CJ;
Esfandiari, A;
Liu, J;
Lu, X;
Hutton, C;
Jackson, J;
Bennaceur, K;
... Lunec, J; + view all
(2016)
TP53 mutant MDM2-amplified cell lines selected for resistance to MDM2-p53 binding antagonists retain sensitivity to ionizing radiation.
Oncotarget
, 7
(29)
pp. 46203-46218.
10.18632/oncotarget.10073.
|
|
|
Dujon, Antoine M;
Aktipis, Athena;
Alix-Panabieres, Catherine;
Amend, Sarah R;
Boddy, Amy M;
Brown, Joel S;
Capp, Jean-Pascal;
... Ujvari, Beata; + view all
(2021)
Identifying key questions in the ecology and evolution of cancer.
Evolutionary Applications
, 14
(4)
pp. 877-892.
10.1111/eva.13190.
|
E
|
Eales, O;
Page, AJ;
De Oliveira Martins, L;
Wang, H;
Bodinier, B;
Haw, D;
Jonnerby, J;
... Elliott, P; + view all
(2022)
SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2.
BMC Infectious Diseases
, 22
, Article 647. 10.1186/s12879-022-07628-4.
|
|
Easom, NJW;
Marks, M;
Jobe, D;
Gillmore, R;
Meyer, T;
Maini, MK;
Njie, R;
(2020)
ULBP1 Is Elevated in Human Hepatocellular Carcinoma and Predicts Outcome.
Frontiers in Oncology
, 10
, Article 971. 10.3389/fonc.2020.00971.
|
|
|
Eccles, SA;
Aboagye, EO;
Ali, S;
Anderson, AS;
Armes, J;
Berditchevski, F;
Blaydes, JP;
... Thompson, AM; + view all
(2013)
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.
Breast Cancer Research
, 15
(5)
, Article R92. 10.1186/bcr3493.
|
|
Edeline, Julien;
Meyer, Tim;
Blanc, Jean-Frédéric;
Raoul, Jean-Luc;
(2022)
New Challenges Facing Systemic Therapies of Advanced HCC in the Era of Different First-Line Immunotherapy-Based Combinations.
Cancers
, 14
(23)
, Article 5868. 10.3390/cancers14235868.
|
|
Edeline, J;
Blanc, J-F;
Campillo-Gimenez, B;
Ma, Y-T;
King, J;
Faluyi, O;
Mathurin, J;
... Meyer, T; + view all
(2017)
Prognostic scores for sorafenib-treated hepatocellular carcinoma patients: A new application for the hepatoma arterial embolisation prognostic score.
European Journal of Cancer
, 86
pp. 135-142.
10.1016/j.ejca.2017.08.036.
|
|
Edeline, J;
Blanc, JF;
Johnson, P;
Campillo-Gimenez, B;
Ross, P;
Ma, YT;
King, J;
... Meyer, T; + view all
(2016)
A multicentre comparison between Child Pugh and Albumin-Bilirubin scores in patients treated with sorafenib for Hepatocellular Carcinoma.
Liver International
, 36
(12)
pp. 1821-1828.
10.1111/liv.13170.
|
|
Eickholt, BJ;
Ahmed, AI;
Davies, M;
Papakonstanti, EA;
Pearce, W;
Starkey, ML;
Bilando, A;
... Vanhaesebroeck, B; + view all
(2007)
Control of Axonal Growth and Regeneration of Sensory Neurons by the p110 delta PI 3-Kinase.
PLOS ONE
, 2
(9)
, Article e869. 10.1371/journal.pone.0000869.
|
|
|
Eisenblaetter, M;
Flores-Borja, F;
Lee, JJ;
Wefers, C;
Smith, H;
Hueting, R;
Cooper, MS;
... Ng, T; + view all
(2017)
Visualization of Tumor-Immune Interaction - Target-Specific Imaging of S100A8/A9 Reveals Pre-Metastatic Niche Establishment.
Theranostics
, 7
(9)
pp. 2392-2401.
10.7150/thno.17138.
|
|
|
El Bairi, K;
Haynes, HR;
Blackley, E;
Fineberg, S;
Shear, J;
Turner, S;
de Freitas, JR;
... Bautista, V; + view all
(2021)
The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group.
npj Breast Cancer
, 7
, Article 150. 10.1038/s41523-021-00346-1.
|
|
|
El-Khoueiry, AB;
Trojan, J;
Meyer, T;
Yau, T;
Melero, I;
Kudo, M;
Hsu, C;
... Sangro, B; + view all
(2024)
Nivolumab in sorafenib-naive and sorafenib-experienced patients with advanced hepatocellular carcinoma: 5-year follow-up from CheckMate 040.
Annals of Oncology
10.1016/j.annonc.2023.12.008.
(In press).
|
|
El-Khoueiry, Anthony B;
Meyer, Tim;
Cheng, Ann-Lii;
Rimassa, Lorenza;
Sen, Suvajit;
Milwee, Steven;
Kelley, Robin Kate;
(2022)
Safety and efficacy of cabozantinib for patients with advanced hepatocellular carcinoma who advanced to Child-Pugh B liver function at study week 8: a retrospective analysis of the CELESTIAL randomised controlled trial.
BMC Cancer
, 22
, Article 377. 10.1186/s12885-022-09453-z.
|
|
El-Khoueiry, AB;
Sangro, B;
Yau, T;
Crocenzi, TS;
Kudo, M;
Hsu, C;
Kim, T-Y;
... Melero, I; + view all
(2017)
Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial.
Lancet
, 389
(10088)
pp. 2492-2502.
10.1016/S0140-6736(17)31046-2.
|
|
Elliott, MJ;
Butler, CR;
Varanou-Jenkins, A;
Partington, L;
Carvalho, C;
Samuel, E;
Crowley, C;
... Birchall, MA; + view all
(2017)
Tracheal Replacement Therapy with a Stem Cell-Seeded Graft: Lessons from Compassionate Use Application of a GMP-Compliant Tissue-Engineered Medicine.
Stem Cells Translational Medicine
, 6
(6)
pp. 1458-1464.
10.1002/sctm.16-0443.
|
|
|
Emanuel, O;
Liu, J;
Schartinger, VH;
Nei, WL;
Chan, YY;
Tsang, CM;
Riechelmann, H;
... Lechner, M; + view all
(2021)
SSTR2 in Nasopharyngeal Carcinoma: Relationship with Latent EBV Infection and Potential as a Therapeutic Target.
Cancers
, 13
(19)
, Article 4944. 10.3390/cancers13194944.
|
|
|
Eminowicz, G;
Vaja, S;
Gallardo, D;
Kent, C;
Panades, M;
Mathew, T;
Anand, A;
... McCormack, M; + view all
(2025)
Induction chemotherapy followed by chemoradiation in locally advanced cervical cancer: Quality of life outcomes of the GCIG INTERLACE trial.
European Journal of Cancer
, 220
, Article 115375. 10.1016/j.ejca.2025.115375.
|
|
Eminowicz, GKD;
(2016)
Standardisation and optimisation of radical radiotherapy for cervical cancer.
Doctoral thesis , UCL (University College London).
|
|
Endesfelder, David;
Burrell, Rebecca A;
Kanu, Nnennaya;
McGranahan, Nicholas;
Howell, Mike;
Parker, Peter J;
Downward, Julian;
... Kschischo, Maik; + view all
(2014)
Chromosomal instability selects gene copy number variants
encoding core regulators of proliferation in ER+ breast cancer.
Cancer Research
, 74
(17)
pp. 4853-4863.
10.1158/0008-5472.CAN-13-2664.
|
|
|
Enfield, Katey SS;
Colliver, Emma;
Lee, Claudia SY;
Magness, Alastair;
Moore, David A;
Sivakumar, Monica;
Grigoriadis, Kristiana;
... Angelova, Mihaela; + view all
(2024)
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer.
Cancer Discovery
, 14
(1)
pp. 1-30.
10.1158/2159-8290.CD-23-1380.
|
|
Eschweiler, Simon;
Ramírez-Suástegui, Ciro;
Li, Yingcong;
King, Emma;
Chudley, Lindsey;
Thomas, Jaya;
Wood, Oliver;
... Ottensmeier, Christian H; + view all
(2022)
Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs.
Nature
10.1038/s41586-022-04685-2.
(In press).
|
|
Esfandiari, A;
Hawthorne, TA;
Nakjang, S;
Lunec, J;
(2016)
Chemical Inhibition of Wild-Type p53-Induced Phosphatase 1 (WIP1/PPM1D) by GSK2830371 Potentiates the Sensitivity to MDM2 Inhibitors in a p53-Dependent Manner.
Molecular Cancer Therapeutics
, 15
(3)
pp. 379-391.
10.1158/1535-7163.MCT-15-0651.
|
|
|
Espana-Agusti, J;
Warren, A;
Chew, SK;
Adams, DJ;
Matakidou, A;
(2017)
Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis.
Nature Communications
, 8
, Article 2026. 10.1038/s41467-017-02245.
|
|
|
Evans, IC;
Barnes, JL;
Garner, IM;
Pearce, DR;
Maher, TM;
Shi-Wen, X;
Renzoni, EA;
... McAnulty, RJ; + view all
(2016)
Epigenetic Regulation of Cyclooxygenase-2 by methylation of c8orf4 in Pulmonary Fibrosis.
Clinical Science
, 130
(8)
pp. 575-586.
10.1042/CS20150697.
|
|
Evans, R;
Flores-Borja, F;
Nassiri, S;
Miranda, E;
Lawler, K;
Grigoriadis, A;
Monypenny, J;
... Ng, T; + view all
(2019)
Integrin-Mediated Macrophage Adhesion Promotes Lymphovascular Dissemination in Breast Cancer.
Cell Reports
, 27
(7)
1967-1978.e4.
10.1016/j.celrep.2019.04.076.
|
|
|
Evans, TRJ;
Dean, E;
Molife, LR;
Lopez, J;
Ranson, M;
El-Khouly, F;
Zubairi, I;
... Kristeleit, R; + view all
(2019)
Phase 1 dose-finding and pharmacokinetic study of eribulin-liposomal formulation in patients with solid tumours.
British Journal of Cancer
, 120
pp. 379-386.
10.1038/s41416-019-0377-x.
|
|
|
Evison, M;
Barrett, E;
Cheng, A;
Mulla, A;
Walls, G;
Johnston, D;
McAleese, J;
... Faivre-Finn, C; + view all
(2021)
Predicting the Risk of Disease Recurrence and Death Following Curative-intent Radiotherapy for Non-small Cell Lung Cancer: The Development and Validation of Two Scoring Systems From a Large Multicentre UK Cohort.
Clinical Oncology
, 33
(3)
pp. 145-154.
10.1016/j.clon.2020.09.001.
|
|
Ezquer, FE;
Ezquer, ME;
Vicencio, JM;
Calligaris, SD;
(2017)
Two complementary strategies to improve cell engraftment in mesenchymal stem cell-based therapy: Increasing transplanted cell resistance and increasing tissue receptivity.
Cell Adhesion & Migration
, 11
(1)
pp. 110-119.
10.1080/19336918.2016.1197480.
|
F
|
Faivre-Finn, C;
Fenwick, JD;
Franks, KN;
Harrow, S;
Hatton, MQF;
Hiley, C;
McAleese, JJ;
... Toy, E; + view all
(2020)
Reduced Fractionation in Lung Cancer Patients Treated with Curative-intent Radiotherapy during the COVID-19 Pandemic.
Clinical Oncology
, 32
(8)
pp. 481-489.
10.1016/j.clon.2020.05.001.
|
|
Feber, A;
Arya, M;
De Winter, P;
Saqib, M;
Nigam, R;
Malone, PR;
Tan, WS;
... Kelly, JD; + view all
(2015)
Epigenetics Markers of Metastasis and HPV-Induced Tumorigenesis in Penile Cancer.
Clinical Cancer Research
, 21
(5)
pp. 1196-1206.
10.1158/1078-0432.CCR-14-1656.
|
|
|
Feber, A;
Dhami, P;
Dong, L;
de Winter, P;
Tan, WS;
Martínez-Fernández, M;
Paul, DS;
... Kelly, JD; + view all
(2017)
UroMark - a urinary biomarker assay for the detection of bladder cancer.
Clinical Epigenetics
, 9
, Article 8. 10.1186/s13148-016-0303-5.
|
|
|
Feber, A;
Guilhamon, P;
Lechner, M;
Fenton, T;
Wilson, GA;
Thirlwell, C;
Morris, TJ;
... Beck, S; + view all
(2014)
Using high-density DNA methylation arrays to profile copy number alterations.
Genome Biol
, 15
(2)
, Article R30. 10.1186/gb-2014-15-2-r30.
|
|
|
Fendler, A;
Au, L;
Shepherd, STC;
Byrne, F;
Cerrone, M;
Boos, LA;
Rzeniewicz, K;
... Wilkinson, RJ; + view all
(2021)
Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study.
Nature Cancer
10.1038/s43018-021-00275-9.
(In press).
|
|
|
Fendler, A;
Shepherd, STC;
Au, L;
Wilkinson, KA;
Wu, M;
Byrne, F;
Cerrone, M;
... Turajlic, S; + view all
(2021)
Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study.
Nature Cancer
10.1038/s43018-021-00274-w.
(In press).
|
|
|
Fendler, Annika;
Au, Lewis;
Shepherd, Scott TC;
Byrne, Fiona;
Cerrone, Maddalena;
Boos, Laura Amanda;
Rzeniewicz, Karolina;
... Turajlic, Samra; + view all
(2021)
Functional antibody and T-cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study.
Research Square: Durham, NC, USA.
|
|
Feng, FY;
Huang, H-C;
Spratt, DE;
Zhao, SG;
Sandler, HM;
Simko, JP;
Davicioni, E;
... Tran, PT; + view all
(2021)
Validation of a 22-Gene Genomic Classifier in Patients With Recurrent Prostate Cancer An Ancillary Study of the NRG/RTOG 9601 Randomized Clinical Trial.
JAMA Oncology
, 7
(4)
pp. 544-552.
10.1001/jamaoncol.2020.7671.
|
|
|
Fennell, D;
Danson, S;
Woll, P;
Forster, M;
Talbot, D;
Child, J;
Farrelly, L;
... Wheeler, G; + view all
(2020)
Ganetespib in combination with pemetrexed-platinum chemotherapy in patients with pleural Mesothelioma (MESO-02): A phase Ib trial.
Clinical Cancer Research
, 26
(18)
pp. 4748-4755.
10.1158/1078-0432.CCR-20-1306.
|
|
Ferguson, MS;
Chard Dunmall, LS;
Gangeswaran, R;
Marelli, G;
Tysome, JR;
Burns, E;
Whitehead, MA;
... Wang, Y; + view all
(2020)
Transient Inhibition of PI3Kδ Enhances the Therapeutic Effect of Intravenous Delivery of Oncolytic Vaccinia Virus.
Molecular Therapy
10.1016/j.ymthe.2020.02.017.
(In press).
|
|
|
Fernanda Amary, M;
Ye, H;
Berisha, F;
Khatri, B;
Forbes, G;
Lehovsky, K;
Frezza, AM;
... Flanagan, AM; + view all
(2014)
Fibroblastic growth factor receptor 1 amplification in osteosarcoma is associated with poor response to neo-adjuvant chemotherapy.
Cancer Med
, 3
(4)
pp. 980-987.
10.1002/cam4.268.
|
|
|
Fernandez-Perez, Maria P;
Perez-Navarro, Enrique;
Alonso-Gordoa, Teresa;
Conteduca, Vicenza;
Font, Albert;
Vazquez-Estevez, Sergio;
Gonzalez-del-Alba, Aranzazu;
... Gonzalez-Billalabeitia, Enrique; + view all
(2023)
A correlative biomarker study and integrative prognostic model in chemotherapy-naive metastatic castration-resistant prostate cancer treated with enzalutamide.
Prostate
, 83
(4)
pp. 376-384.
10.1002/pros.24469.
|
|
Ferolla, P;
Brizzi, MP;
Meyer, T;
Mansoor, W;
Mazieres, J;
Do Cao, C;
Léna, H;
... Baudin, E; + view all
(2017)
Efficacy and safety of long-acting pasireotide or everolimus alone or in combination in patients with advanced carcinoids of the lung and thymus (LUNA): an open-label, multicentre, randomised, phase 2 trial.
The Lancet Oncology
, 18
(12)
pp. 1652-1664.
10.1016/S1470-2045(17)30681-2.
|
|
Ferrer, M;
Anthony, TG;
Ayres, JS;
Biffi, G;
Brown, JC;
Caan, BJ;
Cespedes Feliciano, EM;
... Janowitz, T; + view all
(2023)
Cachexia: A systemic consequence of progressive, unresolved disease.
Cell
, 186
(9)
pp. 1824-1845.
10.1016/j.cell.2023.03.028.
|
|
Field, N;
Lechner, M;
(2015)
Exploring the implications of HPV infection for head and neck cancer.
Sexually Transmitted Infections
, 91
(4)
pp. 229-230.
10.1136/sextrans-2014-051808.
|
|
|
Finn, RS;
Ikeda, M;
Zhu, AX;
Sung, MW;
Baron, AD;
Kudo, M;
Okusaka, T;
... Llovet, JM; + view all
(2020)
Phase Ib Study of Lenvatinib Plus Pembrolizumab in Patients With Unresectable Hepatocellular Carcinoma.
Journal of Clinical Oncology
10.1200/JCO.20.00808.
(In press).
|
|
|
Fittall, Matthew;
Liu, Justin;
Platt, James;
Ionescu, Maria;
Sheehan, Remarez;
Johal, Sukhmunni;
Mew, Rosie;
... Lee, Lennard YW; + view all
(2023)
The National COVID Cancer Antibody Survey: a hyper-accelerated study proof of principle for cancer research.
British Journal of Cancer
, 128
(11)
pp. 1977-1980.
10.1038/s41416-023-02251-9.
|
|
Fittall, MW;
Brewer, M;
de Boisanger, J;
Kviat, L;
Babiker, A;
Taylor, H;
Saran, F;
... Rosenfelder, N; + view all
(2024)
Predicting Survival with Brain Metastases in the Stereotactic Radiosurgery Era: are Existing Prognostic Scores Still Relevant? Or Can we do Better?
Clinical Oncology
10.1016/j.clon.2024.01.037.
(In press).
|
|
Floerchinger, Alessia;
Klein, Jessica E;
Finkbeiner, Maximiliane SC;
Schaefer, Theresa E;
Fuchs, Gwendolin;
Doerner, Johannes;
Zirngibl, Hubert;
... Engeland, Christine E; + view all
(2023)
A vector-encoded bispecific killer engager to harness virus-activated NK cells as anti-tumor effectors.
Cell Death & Disease
, 14
(2)
, Article 104. 10.1038/s41419-023-05624-3.
|
|
Flores-Borja, F;
Irshad, S;
Gordon, P;
Wong, F;
Sheriff, I;
Tutt, A;
Ng, T;
(2016)
Crosstalk between Innate Lymphoid Cells and Other Immune Cells in the Tumor Microenvironment.
Journal of Immunology Research
, Article 7803091. 10.1155/2016/7803091.
|
|
|
Flux, GD;
O'Sullivan, J;
Gaze, MN;
Prise, KM;
(2017)
Opportunities for research in molecular radiotherapy.
British Journal of Radiology
, 90
(1071)
, Article 20160921. 10.1259/bjr.20160921.
|
|
|
Flynn, Michael J;
Ledermann, Jonathan A;
(2022)
Ovarian cancer recurrence: is the definition of platinum resistance modified by PARPi and other intervening treatments? The evolving landscape in the management of platinum-resistant ovarian cancer.
Cancer Drug Resistance
, 5
(2)
pp. 424-435.
10.20517/cdr.2022.13.
|
|
Flynn, MJ;
(2016)
Mechanistic and pharmacodynamic studies of ADCT-301, an Antibody Drug Conjugate targeting CD25-expressing haematological malignancies.
Doctoral thesis , UCL (University College London).
|
|
Flynn, MJ;
Hartley, JA;
(2017)
The emerging role of anti-CD25 directed therapies as both immune modulators and targeted agents in cancer.
[Review].
British Journal of Haematology
, 179
(1)
pp. 20-35.
10.1111/bjh.14770.
|
|
Flynn, MJ;
Zammarchi, F;
Tyrer, PC;
Akarca, AU;
Janghra, N;
Britten, CE;
Havenith, CEG;
... Hartley, JA; + view all
(2016)
ADCT-301, a Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody-Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies.
Molecular Cancer Therapeutics
, 15
(11)
pp. 2709-2721.
10.1158/1535-7163.MCT-16-0233.
|
|
Folarin, A.A.;
(2008)
Analysis of tumour angio-architecture and blood flow using microcomputed tomography and lattice Boltzmann simulations.
Doctoral thesis , University of London.
|
|
|
Fontana, E;
Arkenau, H-T;
(2020)
Oncology clinical trials during the COVID-19 outbreak: Lessons learnt during the crisis and future opportunities.
Cancer Treatment Reviews
, 88
, Article 102047. 10.1016/j.ctrv.2020.102047.
|
|
|
Formica, V;
Doldo, E;
Antonetti, FR;
Nardecchia, A;
Ferroni, P;
Riondino, S;
Morelli, C;
... Roselli, M; + view all
(2017)
Biological and predictive role of ERCC1 polymorphisms in cancer.
Critical Reviews in Oncology/Hematology
, 111
pp. 133-143.
10.1016/j.critrevonc.2017.01.016.
|
|
Forster, Martin;
Brana, Irene;
Lopez Pousa, Antonio;
Doger, Bernard;
Roxburgh, Patricia;
Bajaj, Pawan;
Peguero, Julio;
... Triebel, Frederic; + view all
(2024)
Eftilagimod Alpha (Soluble LAG3 Protein) Combined with Pembrolizumab as Second-Line Therapy for Patients with Metastatic Head and Neck Squamous Cell Carcinoma.
Clinical Cancer Research
, 30
(17)
pp. 3726-3734.
10.1158/1078-0432.CCR-24-0473.
|
|
Forster, M;
Hackshaw, A;
De Pas, T;
Cobo, M;
Garrido, P;
Summers, Y;
Dingemans, AMC;
... Lee, SM; + view all
(2018)
A phase I study of nintedanib combined with cisplatin/gemcitabine as first-line therapy for advanced squamous non-small cell lung cancer (LUME-Lung 3).
Lung Cancer
, 120
pp. 27-33.
10.1016/j.lungcan.2018.03.007.
|
|
|
Forster, M;
Mendes, R;
Harrington, K;
Guerrero-Urbano, T;
Baines, H;
Spanswick, V;
Ensell, L;
... Beare, S; + view all
(2016)
A phase I study of olaparib in addition to cisplatin-based concurrent chemoradiotherapy for patients with high risk locally advanced squamous cell carcinoma of the head and neck (HNSCC).
Presented at: 2016 ASCO Annual Meeting, Chicago, IL, USA.
|
|
Forster, MD;
Devlin, M-J;
(2018)
Immune Checkpoint Inhibition in Head and Neck Cancer.
Frontiers in Oncology
, 8
, Article 310. 10.3389/fonc.2018.00310.
|
|
|
Forster, MD;
Dillon, MT;
Kocsis, J;
Remenár, É;
Pajkos, G;
Rolland, F;
Greenberg, J;
(2019)
Patritumab or placebo, with cetuximab plus platinum therapy in recurrent or metastatic squamous cell carcinoma of the head and neck: A randomised phase II study.
European Journal of Cancer
, 123
pp. 36-47.
10.1016/j.ejca.2019.08.017.
|
|
|
Forster, MD;
Moschetta, M;
Uccello, M;
Kasenda, B;
Mak, G;
McClelland, A;
Boussios, S;
(2017)
Dynamics of neutrophils to lymphocyte ratio (NLR) predict outcomes of PD-1/PD-L1 blockade.
BioMed Research International
, 2017
, Article 1506824. 10.1155/2017/1506824.
|
|
|
Forte, N;
Livanos, M;
Miranda, E;
Morais, M;
Yang, X;
Rajkumar, VS;
Chester, KA;
... Baker, JR; + view all
(2018)
Tuning the Hydrolytic Stability of Next Generation Maleimide Cross-Linkers Enables Access to Albumin-Antibody Fragment Conjugates and tri-scFvs.
Bioconjugate Chemistry
, 29
(2)
pp. 486-492.
10.1021/acs.bioconjchem.7b00795.
|
|
|
Fostea, RM;
Fontana, E;
Torga, G;
Arkenau, HT;
(2020)
Recent Progress in the Systemic Treatment of Advanced/Metastatic Cholangiocarcinoma.
Cancers
, 12
(9)
, Article 2599. 10.3390/cancers12092599.
|
|
|
Fotopoulou, C;
Hall, M;
Lord, R;
Miller, R;
Sundar, S;
Roebuck, N;
Fildes, L;
... Ledermann, J; + view all
(2024)
Perspectives of Healthcare Professionals on the Management and Treatment of Advanced Ovarian Cancer in the UK: Results From the KNOW-OC Survey.
Clinical Oncology
, 36
(1)
e1-e10.
10.1016/j.clon.2023.10.052.
|
|
Fowler, Daniel;
Barisa, Marta;
Southern, Alba;
Nattress, Callum;
Hawkins, Elizabeth;
Vassalou, Eleni;
Kanouta, Angeliki;
... Fisher, Jonathan; + view all
(2024)
Payload-delivering engineered γδ T cells display enhanced cytotoxicity, persistence, and efficacy in preclinical models of osteosarcoma.
Science Translational Medicine
, 16
(749)
, Article eadg9814. 10.1126/scitranslmed.adg9814.
|
|
|
Foxall, E;
Pipili, A;
Jones, GE;
Wells, CM;
(2016)
Significance of kinase activity in the dynamic invadosome.
European Journal of Cell Biology
, 95
(11)
pp. 483-492.
10.1016/j.ejcb.2016.07.002.
|
|
|
Foxall, E;
Staszowska, A;
Hirvonen, LM;
Georgouli, M;
Ciccioli, M;
Rimmer, A;
Williams, L;
... Wells, CM; + view all
(2019)
PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells.
Cell Reports
, 29
(11)
3385-3393.e6.
10.1016/j.celrep.2019.11.016.
|
|
|
Foy, V;
Schenk, MW;
Baker, K;
Gomes, F;
Lallo, A;
Frese, KK;
Forster, M;
... Blackhall, F; + view all
(2017)
Targeting DNA damage in SCLC.
[Review].
Lung Cancer
, 114
pp. 12-22.
10.1016/j.lungcan.2017.10.006.
|
|
Francis, Katherine E;
Simon, Sandy;
Gebski, Val;
Joly, Florence;
Ledermann, Jonathan A;
Penson, Richard T;
Oza, Amit M;
... Lee, Chee Khoon; + view all
(2025)
Adverse events in the placebo arm of SOLO2/ENGOT-Ov21 maintenance trial of olaparib in recurrent ovarian cancer.
Gynecologic Oncology
, 192
pp. 50-55.
10.1016/j.ygyno.2024.11.004.
(In press).
|
|
Francis, R.J.;
(2005)
Antibody directed enzyme prodrug therapy - a mechanistic approach.
Doctoral thesis , University of London.
|
|
|
Frankell, Alexander M;
Dietzen, Michelle;
Al Bakir, Maise;
Lim, Emilia L;
Karasaki, Takahiro;
Ward, Sophia;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2024)
The evolution of lung cancer and impact of subclonal selection in TRACERx (vol 616, pg 525, 2023).
[Corrigendum].
Nature
, 631
, Article E15. 10.1038/s41586-024-07738-w.
|
|
|
Frankell, AM;
Dietzen, M;
Al Bakir, M;
Lim, EL;
Karasaki, T;
Ward, S;
Veeriah, S;
... Gilbert, K; + view all
(2023)
The evolution of lung cancer and impact of subclonal selection in TRACERx.
Nature
, 616
pp. 525-533.
10.1038/s41586-023-05783-5.
|
|
Frauenfelder, C;
Hall, A;
Walsh, B;
Ross, A;
Broughton, E;
Hynds, RE;
Nandi, R;
... Butler, CR; + view all
(2022)
Use of Simulation to Visualize Healthcare Worker Exposure to Aerosol in the Operating Room.
Simulation in Healthcare
, 17
(1)
pp. 66-67.
10.1097/SIH.0000000000000581.
|
|
Freemantle, Nick;
Mollon, Patrick;
Meyer, Tim;
Cheng, Ann-Lii;
El-Khoueiry, Anthony B;
Kelley, Robin K;
Baron, Ari D;
... Abou-Alfa, Ghassan K; + view all
(2022)
Quality of life assessment of cabozantinib in patients with advanced hepatocellular carcinoma in the CELESTIAL trial.
European Journal of Cancer
, 168
pp. 91-98.
10.1016/j.ejca.2022.03.021.
|
|
Frenel, JS;
Kim, JW;
Aryal, N;
Asher, R;
Berton, D;
Vidal, L;
Pautier, P;
... Pujade-Lauraine, E; + view all
(2022)
Efficacy of subsequent chemotherapy for patients with BRCA1/2-mutated recurrent epithelial ovarian cancer progressing on olaparib versus placebo maintenance: post-hoc analyses of the SOLO2/ENGOT Ov-21 trial.
Annals of Oncology
, 33
(10)
pp. 1021-1028.
10.1016/j.annonc.2022.06.011.
|
|
Frezza, AM;
Beale, T;
Bomanji, J;
Jay, A;
Kalavrezos, N;
Dileo, P;
Whelan, J;
(2014)
Is [F-18]-fluorodeoxy-D-glucose positron emission tomography of value in the management of patients with craniofacial bone sarcomas undergoing neo-adjuvant treatment?
BMC Cancer
, 14
, Article 23. 10.1186/1471-2407-14-23.
|
|
|
Friedmann, Benjamin Jacob;
(2006)
Modulation of chemotherapy by inhibition of the epidermal growth factor receptor.
Doctoral thesis , UCL (University College London).
|
|
Frizziero, M;
Kilgour, E;
Simpson, KL;
Rothwell, DG;
Moore, DA;
Frese, KK;
Galvin, M;
... Dive, C; + view all
(2022)
Expanding Therapeutic Opportunities for Extrapulmonary Neuroendocrine Carcinoma.
Clinical Cancer Research
, 28
(10)
pp. 1999-2019.
10.1158/1078-0432.CCR-21-3058.
|
|
Frizziero, M;
Wang, X;
Chakrabarty, B;
Childs, A;
Luong, TV;
Walter, T;
Khan, MS;
... McNamara, MG; + view all
(2019)
Retrospective study on mixed neuroendocrine non-neuroendocrine neoplasms from five European centres.
World Journal of Gastroenterology
, 25
(39)
pp. 5991-6005.
10.3748/wjg.v25.i39.5991.
|
|
|
Fu, X;
Zhao, Y;
Lopez, JI;
Rowan, A;
Au, L;
Fendler, A;
Hazell, S;
... Bates, PA; + view all
(2021)
Spatial patterns of tumour growth impact clonal diversification in a computational model and the TRACERx Renal study.
Nature Ecology & Evolution
10.1038/s41559-021-01586-x.
|
|
|
Futter, CE;
Tomas, A;
Vaughan, SO;
Burgoyne, T;
Sorkin, A;
Hochhauser, D;
(2015)
WASH and Tsg101/ALIX-dependent diversion of stress-internalised EGFR from the canonical endocytic pathway.
Nature Communications
, 6
, Article 7324. 10.1038/ncomms8324.
|
G
|
Gadaleta, E;
Fourgoux, P;
Pirró, S;
Thorn, GJ;
Nelan, R;
Ironside, A;
Rajeeve, V;
... Chelala, C; + view all
(2020)
Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer.
npj Breast Cancer
, 6
, Article 38. 10.1038/s41523-020-00182-9.
|
|
|
Gaillard, Thomas;
Schwameis, Richard;
Laas-Faron, Enora;
Eisenberg-Nissim, Tali;
Matias-Guiu, Xavier;
Creutzberg, Carien L;
Ledermann, Jonathan;
... Concin, Nicole; + view all
(2023)
An easy, fast, and accurate way for implementing the standards of care for the management of patients with endometrial carcinoma into daily clinical practice: the ESGO mobile app.
International Journal of Gynecological Cancer
, 33
(8)
pp. 1181-1184.
10.1136/ijgc-2023-004598.
|
|
Gains, JE;
(2015)
Improving the outcomes for high-risk neuroblastoma through the optimisation of radiotherapeutic techniques.
Doctoral thesis , UCL (University College London).
|
|
Galvez-Cancino, Felipe;
Simpson, Alexander P;
Costoya, Cristobal;
Matos, Ignacio;
Qian, Danwen;
Peggs, Karl S;
Litchfield, Kevin;
(2023)
Fcγ receptors and immunomodulatory antibodies in cancer.
Nature Reviews Cancer
, 24
(1)
pp. 51-71.
10.1038/s41568-023-00637-8.
|
|
Ganeshan, B;
Miles, K;
Afaq, A;
Punwani, S;
Rodriguez, M;
Wan, S;
Walls, D;
... Groves, A; + view all
(2021)
Texture Analysis of Fractional Water Content Images Acquired during PET/MRI: Initial Evidence for an Association with Total Lesion Glycolysis, Survival and Gene Mutation Profile in Primary Colorectal Cancer.
Cancers
, 13
(11)
, Article 2715. 10.3390/cancers13112715.
|
|
|
Ganguli, Sushila;
(2022)
The Effects of Oncogenic Ras on Epithelial Cell Division.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
|
Ganguli, Sushila;
Wyatt, Tom;
Nyga, Agata;
Lawson, Rachel H;
Meyer, Tim;
Baum, Buzz;
Matthews, Helen K;
(2023)
Oncogenic Ras deregulates cell-substrate interactions during mitotic rounding and respreading to alter cell division orientation.
Current Biology
10.1016/j.cub.2023.05.061.
(In press).
|
|
Gao, D;
Barber, PR;
Chacko, JV;
Kader Sagar, MA;
Rueden, CT;
Grislis, AR;
Hiner, MC;
(2020)
FLIMJ: An open-source ImageJ toolkit for fluorescence lifetime image data analysis.
PLoS One
, 15
(12)
, Article e0238327. 10.1371/journal.pone.0238327.
|
|
|
Garrigós, L;
Saura, C;
Martinez-Vila, C;
Zambelli, A;
Bower, M;
Pistilli, B;
Lambertini, M;
... Gennari, A; + view all
(2021)
COVID-19 in breast cancer patients: a subanalysis of the OnCovid registry.
Therapeutic Advances in Medical Oncology
, 13
pp. 1-11.
10.1177/17588359211053416.
|
|
|
Gaspar, N;
Campbell-Hewson, Q;
Gallego Melcon, S;
Locatelli, F;
Venkatramani, R;
Hecker-Nolting, S;
Gambart, M;
... Casanova, M; + view all
(2021)
Phase I/II study of single-agent lenvatinib in children and adolescents with refractory or relapsed solid malignancies and young adults with osteosarcoma (ITCC-050).
ESMO Open
, 6
(5)
, Article 100250. 10.1016/j.esmoop.2021.100250.
|
|
|
Gaspar, N;
Venkatramani, R;
Hecker-Nolting, S;
Melcon, SG;
Locatelli, F;
Bautista, F;
Longhi, A;
... Campbell-Hewson, Q; + view all
(2021)
Lenvatinib with etoposide plus ifosfamide in patients with refractory or relapsed osteosarcoma (ITCC-050): a multicentre, open-label, multicohort, phase 1/2 study.
Lancet Oncology
, 22
(9)
pp. 1312-1321.
10.1016/S1470-2045(21)00387-9.
|
|
Gaze, MN;
Smeulders, N;
Ackwerh, R;
Allen, C;
Bal, N;
Boutros, M;
Cho, A;
... Hoskin, PJ; + view all
(2023)
A National Referral Service for Paediatric Brachytherapy: An Evolving Practice and Outcomes Over 13 Years.
Clinical Oncology
, 35
(4)
pp. 237-244.
10.1016/j.clon.2022.12.008.
|
|
Genoud, Vassilis;
Kinnersley, Ben;
Brown, Nicholas F;
Ottaviani, Diego;
Mulholland, Paul;
(2023)
Therapeutic Targeting of Glioblastoma and the Interactions with Its Microenvironment.
Cancers
, 15
(24)
, Article 5790. 10.3390/cancers15245790.
|
|
George, A;
Kristeleit, R;
Rafii, S;
Michie, CO;
Bowen, R;
Michalarea, V;
van Hagen, T;
... Yap, TA; + view all
(2017)
Clinical factors of response in patients with advanced ovarian cancer participating in early phase clinical trials.
European Journal of Cancer
, 76
pp. 52-59.
10.1016/j.ejca.2017.01.020.
|
|
Geukens, Tatjana;
Maetens, Marion;
Hooper, Jody E;
Oesterreich, Steffi;
Lee, Adrian;
Miller, Lori;
Atkinson, Jenny M;
... Desmedt, Christine; + view all
(2024)
Research autopsy programmes in oncology: shared experience from 14 centres across the world.
The Journal of Pathology
10.1002/path.6271.
(In press).
|
|
Ghimire, Prajwal;
Kinnersley, Ben;
Karami, Golestan;
Arumugam, Prabhu;
Houlston, Richard;
Ashkan, Keyoumars;
Modat, Marc;
(2024)
Radiogenomic biomarkers for immunotherapy in glioblastoma: A systematic review of magnetic resonance imaging studies.
Neuro-Oncology Advances
, 6
(1)
, Article vdae055. 10.1093/noajnl/vdae055.
(In press).
|
|
|
Ghorani, E;
Reading, JL;
Henry, JY;
Massy, MRD;
Rosenthal, R;
Turati, V;
Joshi, K;
... Quezada, SA; + view all
(2020)
The T cell differentiation landscape is shaped by tumour mutations in lung cancer.
Nature Cancer
, 1
(5)
pp. 546-561.
10.1038/s43018-020-0066-y.
|
|
Ghorani, E;
Rosenthal, R;
McGranahan, N;
Reading, JL;
Lynch, M;
Peggs, KS;
Swanton, C;
(2018)
Differential binding affinity of mutated peptides for MHC class I is a predictor of survival in advanced lung cancer and melanoma.
Annals of Oncology
, 29
(1)
pp. 271-279.
10.1093/annonc/mdx687.
|
|
|
Gilks, C Blake;
Selinger, Christina I;
Davidson, Ben;
Köbel, Martin;
Ledermann, Jonathan A;
Lim, Diana;
Malpica, Anais;
... McCluggage, W Glenn; + view all
(2022)
Data Set for the Reporting of Ovarian, Fallopian Tube and Primary Peritoneal Carcinoma: Recommendations From the International Collaboration on Cancer Reporting (ICCR).
International Journal of Gynecological Pathology
, 41
(6)
S119-S142.
10.1097/PGP.0000000000000908.
|
|
Gillessen, Silke;
Turco, Fabio;
Davis, Ian D;
Efstathiou, Jason A;
Fizazi, Karim;
James, Nicholas D;
Shore, Neal;
... Omlin, Aurelius; + view all
(2025)
Management of Patients with Advanced Prostate Cancer. Report from the 2024 Advanced Prostate Cancer Consensus Conference (APCCC).
European Urology
, 87
(2)
pp. 157-216.
10.1016/j.eururo.2024.09.017.
|
|
|
Gillessen, S;
Attard, G;
Beer, TM;
Beltran, H;
Bjartell, A;
Bossi, A;
Briganti, A;
... Omlin, A; + view all
(2020)
Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2019.
European Urology
10.1016/j.eururo.2020.01.012.
(In press).
|
|
|
Gillessen, S;
Attard, G;
Beer, TM;
Beltran, H;
Bossi, A;
Bristow, R;
Carver, B;
... Omlin, A; + view all
(2018)
Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017.
European Urology
, 73
(2)
pp. 178-211.
10.1016/j.eururo.2017.06.002.
|
|
Gillessen, S;
Omlin, A;
Attard, G;
de Bono, JS;
Efstathiou, E;
Fizazi, K;
Halabi, S;
... Tombal, B; + view all
(2016)
Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015.
Annals of Oncology
, 26
pp. 1589-1604.
10.1093/annonc/mdw180.
|
|
|
Gilson, C;
Ingleby, F;
Gilbert, DC;
Parry, MA;
Atako, NB;
Ali, A;
Hoyle, A;
... Chowdhury, S; + view all
(2020)
Genomic Profiles of De Novo High- and Low-Volume Metastatic Prostate Cancer: Results From a 2-Stage Feasibility and Prevalence Study in the STAMPEDE Trial.
JCO Precision Oncology
, 4
pp. 882-897.
10.1200/po.19.00388.
|
|
Gimeno-Valiente, Francisco;
Castignani, Carla;
Larose Cadieux, Elizabeth;
Mensah, Nana E;
Liu, Xiaohong;
Chen, Kezhong;
Chervova, Olga;
... Kanu, Nnennaya; + view all
(2025)
DNA methylation co-operates with genomic alterations during non-small cell lung cancer evolution.
Nature Genetics
(In press).
|
|
Glosli, H;
Bisogno, G;
Kelsey, A;
Chisholm, JC;
Gaze, M;
Kolb, F;
McHugh, K;
... Orbach, D; + view all
(2021)
Non-parameningeal head and neck rhabdomyosarcoma in children, adolescents, and young adults: Experience of the European paediatric Soft tissue sarcoma Study Group (EpSSG) – RMS2005 study.
European Journal of Cancer
, 151
pp. 84-93.
10.1016/j.ejca.2021.04.007.
|
|
Goh, Vicky;
Mallett, Susan;
Boulter, Victor;
Glynne-Jones, Robert;
Khan, Saif;
Lessels, Sarah;
Patel, Dominic;
... Halligan, Steve; + view all
(2024)
Multivariable prognostic modelling to improve prediction of colorectal cancer recurrence: the PROSPeCT trial.
European Radiology
10.1007/s00330-024-10803-7.
(In press).
|
|
Goh, G;
Schmid, R;
Guiver, K;
Arpornwirat, W;
Chitapanarux, I;
Ganju, V;
Im, SA;
... Swanton, C; + view all
(2016)
Clonal Evolutionary Analysis during HER2 Blockade in HER2-Positive Inflammatory Breast Cancer: A Phase II Open-Label Clinical Trial of Afatinib +/- Vinorelbine.
PLOS Med
, 13
(12)
, Article e1002136. 10.1371/journal.pmed.1002136.
|
|
Golan, T;
Hammel, P;
Reni, M;
Van Cutsem, E;
Macarulla, T;
Hall, MJ;
Park, J-O;
... Kindler, HL; + view all
(2019)
Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer.
The New England Journal of Medicine
, 381
pp. 317-327.
10.1056/NEJMoa1903387.
|
|
Goldstein, R;
Sosabowski, J;
Livanos, M;
Leyton, J;
Vigor, K;
Bhavsar, G;
Nagy-Davidescu, G;
... Chester, K; + view all
(2015)
Development of the designed ankyrin repeat protein (DARPin) G3 for HER2 molecular imaging.
Eur J Nucl Med Mol Imaging
, 42
(2)
288 - 301.
10.1007/s00259-014-2940-2.
|
|
|
Goldstein, RM;
(2015)
Development of the G3 Designed ankyrin repeat protein (DARPin) for HER2 imaging.
Doctoral thesis , UCL (University College London).
|
|
|
Gomez, V;
Galazi, M;
Weitsman, G;
Monypenny, J;
Al-Salemee, F;
Barber, P;
Ng, K;
... Ng, T; + view all
(2022)
HER2 mediates PSMA/mGluR1-driven resistance to the DS-7423 dual PI3K/mTOR inhibitor in PTEN wild-type prostate cancer models.
Molecular Cancer Therapeutics
, 21
(4)
pp. 667-676.
10.1158/1535-7163.MCT-21-0320.
|
|
Gomez, V;
(2020)
Breast cancer-associated macrophages promote tumorigenesis by suppressing succinate dehydrogenase in tumor cells.
Science Signaling
, 13
(652)
, Article eaax4585. 10.1126/scisignal.aax4585.
|
|
Gomez, V;
Mustapha, R;
Ng, K;
Ng, T;
(2020)
Radiation therapy and the innate immune response: clinical implications for immunotherapy approaches.
British Journal of Clinical Pharmacology
, 86
(9)
pp. 1726-1735.
10.1111/bcp.14351.
|
|
|
Goncalves, T;
Zoumpoulidou, G;
Alvarez-Mendoza, C;
Mancusi, C;
Collopy, LC;
Strauss, SJ;
Mittnacht, S;
(2020)
Selective Elimination of Osteosarcoma Cell Lines with Short Telomeres by Ataxia Telangiectasia and Rad3-Related Inhibitors.
ACS Pharmacology & Translational Science
, 3
(6)
pp. 1253-1264.
10.1021/acsptsci.0c00125.
|
|
Gong, Grace Q;
Bilanges, Benoit;
Allsop, Ben;
Masson, Glenn R;
Roberton, Victoria;
Askwith, Trevor;
Oxenford, Sally;
... Vanhaesebroeck, Bart; + view all
(2023)
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration.
Nature
, 618
pp. 159-168.
10.1038/s41586-023-05972-2.
|
|
|
Gong, Grace Q;
Vanhaesebroeck, Bart;
(2024)
Precision Targeting of Mutant PI3Kα.
Cancer Discovery
, 14
(2)
pp. 204-207.
10.1158/2159-8290.cd-23-1392.
|
|
González-Billalabeitia, E;
Conteduca, V;
Wetterskog, D;
Jayaram, A;
Attard, G;
(2019)
Circulating tumor DNA in advanced prostate cancer: transitioning from discovery to a clinically implemented test.
Prostate Cancer and Prostatic Diseases
, 22
pp. 195-205.
10.1038/s41391-018-0098-x.
|
|
Gonzalez-Ericsson, P;
Stovgaard, ES;
Sua, LF;
Reisenbichler, E;
Kos, Z;
Carter, JM;
Michiels, S;
... Sanders, M; + view all
(2020)
The path to a better biomarker: application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice.
The Journal of Pathology
, 250
(5)
pp. 667-684.
10.1002/path.5406.
|
|
González-Martín, A;
Harter, P;
Leary, A;
Lorusso, D;
Miller, RE;
Pothuri, B;
Ray-Coquard, I;
... ESMO Guidelines Committee; + view all
(2023)
Newly diagnosed and relapsed epithelial ovarian cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
Annals of Oncology
, 34
(10)
pp. 833-848.
10.1016/j.annonc.2023.07.011.
|
|
Gowers, KHC;
Hynds, RE;
Thakrar, RM;
Carroll, B;
Birchall, MA;
Janes, SM;
(2017)
Optimized isolation and expansion of human airway epithelial basal cells from endobronchial biopsy samples.
Journal of Tissue Engineering and Regenerative Medicine
10.1002/term.2466.
(In press).
|
|
|
Goyal, L;
Kongpetch, S;
Crolley, VE;
Bridgewater, J;
(2021)
Targeting FGFR inhibition in cholangiocarcinoma.
Cancer Treatment Reviews
, 95
, Article 102170. 10.1016/j.ctrv.2021.102170.
|
|
Graham, MS;
Sudre, CH;
May, A;
Antonelli, M;
Murray, B;
Varsaysky, T;
Klaser, K;
... Ourselin, S; + view all
(2021)
Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study.
Lancet Public Health
, 6
(5)
E335-E345.
10.1016/S2468-2667(21)00055-4.
|
|
|
Green, S;
Tuck, S;
Long, J;
Green, T;
Green, A;
Ellis, P;
Haire, A;
... Van Hemelrijck, M; + view all
(2021)
ReIMAGINE: a prostate cancer research consortium with added value through its patient and public involvement and engagement.
Research Involvement and Engagement
, 7
(1)
, Article 81. 10.1186/s40900-021-00322-w.
|
|
|
Greenwood, Hannah E;
Barber, Abigail R;
Edwards, Richard S;
Tyrrell, Will E;
George, Madeleine E;
Dos Santos, Sofia N;
Baark, Friedrich;
... Witney, Timothy H; + view all
(2024)
Imaging NRF2 activation in non-small cell lung cancer with positron emission tomography.
Nature Communications
, 15
, Article 10484. 10.1038/s41467-024-54852-4.
|
|
|
Greenwood, HE;
McCormick, PN;
Gendron, T;
Glaser, M;
Pereira, R;
Maddocks, ODK;
Sander, K;
... Witney, TH; + view all
(2019)
Measurement of Tumor Antioxidant Capacity and Prediction of Chemotherapy Resistance in Preclinical Models of Ovarian Cancer by Positron Emission Tomography.
Clinical Cancer Research
, 25
(8)
pp. 2471-2482.
10.1158/1078-0432.CCR-18-3423.
|
|
Grey, William;
Rio-Machin, Ana;
Casado, Pedro;
Grönroos, Eva;
Ali, Sara;
Miettinen, Juho J;
Bewicke-Copley, Findlay;
... Bonnet, Dominique; + view all
(2022)
CKS1 inhibition depletes leukemic stem cells and protects healthy hematopoietic stem cells in acute myeloid leukemia.
Science Translational Medicine
, 14
(650)
, Article eabn3248. 10.1126/scitranslmed.abn3248.
|
|
Greystoke, A;
Steele, N;
Arkenau, H-T;
Blackhall, F;
Haris, NM;
Lindsay, CR;
Califano, R;
... Dean, E; + view all
(2017)
SELECT-3: a phase I study of selumetinib in combination with platinum-doublet chemotherapy for advanced NSCLC in the first-line setting.
British Journal of Cancer
, 117
pp. 938-946.
10.1038/bjc.2017.271.
|
 |
|
Grieco, G;
Janssens, V;
Chevronnay, HPG;
N'Kuli, F;
Van Der Smissen, P;
Wang, T;
Shan, J;
... Courtoy, PJ; + view all
(2018)
Vps34/PI3KC3 deletion in kidney proximal tubules impairs apical trafficking and blocks autophagic flux, causing a Fanconi-like syndrome and renal insufficiency.
Scientific Reports
, 8
, Article 14133. 10.1038/s41598-018-32389-z.
|
|
|
Grieco, G;
Wang, T;
Delcorte, O;
Spourquet, C;
Janssens, V;
Strickaert, A;
Gaide Chevronnay, H;
... Pierreux, CE; + view all
(2020)
Vps34 PI 3-kinase controls thyroid hormone production by regulating thyroglobulin iodination, lysosomal proteolysis and tissue homeostasis.
Thyroid
, 30
(1)
pp. 133-146.
10.1089/thy.2019.0182.
|
|
Grigoriadis, Kristiana;
Huebner, Ariana;
Bunkum, Abigail;
Colliver, Emma;
Frankell, Alexander M;
Hill, Mark S;
Thol, Kerstin;
... McGranahan, Nicholas; + view all
(2024)
CONIPHER: a computational framework for scalable phylogenetic reconstruction with error correction.
Nature Protocols
, 19
pp. 159-183.
10.1038/s41596-023-00913-9.
|
|
|
Grillone, Katia;
Ascrizzi, Serena;
Cremaschi, Paolo;
Amato, Jussara;
Polerà, Nicoletta;
Croci, Ottavio;
Rocca, Roberta;
... Tassone, Pierfrancesco; + view all
(2024)
An unbiased lncRNAs dropout CRISPR-Cas9 screen reveals RP11-350G8.5 as a novel therapeutic target for Multiple Myeloma.
Blood
10.1182/blood.2023021991.
|
|
Grist, Emily;
(2022)
Biomarker Development for Advanced Prostate Cancer.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Gronchi, A;
Miah, AB;
DeiTos, AP;
Abecassis, N;
Bajpai, J;
Bauer, S;
Biagini, R;
... Stacchiotti, S; + view all
(2021)
Soft tissue and visceral sarcomas: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Annals of Oncology
, 32
(11)
pp. 1348-1365.
10.1016/j.annonc.2021.07.006.
|
|
Guest, JF;
Panca, M;
Sladkevicius, E;
Gough, N;
Linch, M;
(2013)
Cost Effectiveness of First-Line Treatment with Doxorubicin/Ifosfamide Compared to Trabectedin Monotherapy in the Management of Advanced Soft Tissue Sarcoma in Italy, Spain, and Sweden.
Sarcoma
, 2013
pp. 1-19.
10.1155/2013/725305.
|
|
|
Guilhamon, P;
Eskandarpour, M;
Halai, D;
Wilson, GA;
Feber, A;
Teschendorff, AE;
Gomez, V;
... Beck, S; + view all
(2013)
Meta-analysis of IDH-mutant cancers identifies EBF1 as an interaction partner for TET2.
Nature Communications
, 4
, Article 2166. 10.1038/ncomms3166.
|
|
|
Guillermet-Guibert, J;
Smith, LB;
Halet, G;
Whitehead, MA;
Pearce, W;
Rebourcet, D;
León, K;
... Vanhaesebroeck, B; + view all
(2015)
Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells.
PLoS Genetics
, 11
(7)
, Article e1005304. 10.1371/journal.pgen.1005304.
|
|
|
Guillotin, D;
Taylor, AR;
Platé, M;
Mercer, PF;
Edwards, LM;
Haggart, R;
Miele, G;
... Chambers, RC; + view all
(2020)
Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis.
Thorax
, 76
(1)
pp. 73-82.
10.1136/thoraxjnl-2020-214902.
|
|
|
Gundogdu, R;
Erdogan, MK;
Ditsiou, A;
Spanswick, V;
Garcia-Gomez, JJ;
Hartley, JA;
Esashi, F;
... Gomez, V; + view all
(2021)
hMOB2 deficiency impairs homologous recombination-mediated DNA repair and sensitises cancer cells to PARP inhibitors.
Cellular Signalling
, 87
, Article 110106. 10.1016/j.cellsig.2021.110106.
|
|
|
Guo, C;
Crespo, M;
Gurel, B;
Dolling, D;
Rekowski, J;
Sharp, A;
Petremolo, A;
... International SU2C PCF Prostate Cancer Dream Team, .; + view all
(2021)
CD38 in Advanced Prostate Cancers.
European Urology
, 79
(6)
pp. 736-746.
10.1016/j.eururo.2021.01.017.
|
|
|
Gupta, RK;
Marks, M;
Edwards, SG;
Smith, K;
Fletcher, K;
Lee, SM;
Ramsay, A;
... Miller, RF; + view all
(2014)
A declining CD4 count and diagnosis of HIV-associated hodgkin Lymphoma: Do prior clinical symptoms and laboratory abnormalities aid diagnosis?
PLoS One
, 9
(2)
, Article e87442. 10.1371/journal.pone.0087442.
|
|
|
Gurusamy, K;
Corrigan, N;
Croft, J;
Twiddy, M;
Morris, S;
Woodward, N;
Bandula, S;
... Davidson, BR; + view all
(2018)
Liver resection surgery versus thermal ablation for colorectal LiVer MetAstases (LAVA): study protocol for a randomised controlled trial.
Trials
, 19
, Article 105. 10.1186/s13063-018-2499-5.
|
|
H
|
Haggstrom, LR;
Lee, YC;
Scott, CL;
Ledermann, JA;
Gourley, C;
McNeish, I;
Amant, F;
... Friedlander, ML; + view all
(2024)
764P How long is long enough? An international survey exploring practice variations on the recommended duration of maintenance therapy with PARP inhibitors in platinum sensitive recurrent ovarian cancer and long-term outcomes.
In: Powles, T, (ed.)
Annals of Oncology.
(pp. S578-S579).
Elsevier Ltd: Barcelona, Spain.
|
|
Haggstrom, Lucy;
Lee, Yeh Chen;
Scott, Clare;
Harter, Philipp;
Woelber, Linn;
Ledermann, Jonathan;
Gourley, Charlie;
... Friedlander, Michael L; + view all
(2024)
How long is long enough? An international survey exploring practice variations on the recommended duration of maintenance therapy with PARP inhibitors in patients with platinum sensitive recurrent ovarian cancer and long-term outcomes.
International Journal of Gynecological Cancer
, 34
(12)
pp. 1932-1939.
10.1136/ijgc-2024-005976.
|
|
Hagos, Yeman B;
Lecat, Catherine SY;
Patel, Dominic;
Mikolajczak, Anna;
Castillo, Simon P;
Lyon, Emma J;
Foster, Kane;
... Yuan, Yinyin; + view all
(2023)
Deep learning enables spatial mapping of the mosaic microenvironment of myeloma bone marrow trephine biopsies.
Cancer Research
10.1158/0008-5472.can-22-2654.
|
|
|
Hainsworth, JD;
Meric-Bernstam, F;
Swanton, C;
Hurwitz, H;
Spigel, DR;
Sweeney, C;
Burris, H;
... Kurzrock, R; + view all
(2018)
Targeted Therapy for Advanced Solid Tumors on the Basis of Molecular Profiles: Results From MyPathway, an Open-Label, Phase IIa Multiple Basket Study.
Journal of Clinical Oncology
, 36
(6)
pp. 536-544.
10.1200/JCO.2017.75.3780.
|
|
|
Hall, AR;
Burke, N;
Dongworth, RK;
Kalkhoran, SB;
Dyson, A;
Vicencio, JM;
Dorn Ii, GW;
... Hausenloy, DJ; + view all
(2016)
Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction.
Cell Death and Disease
, 7
, Article e2238. 10.1038/cddis.2016.139.
|
|
|
Hamaguchi, A.;
(2006)
Molecular and cellular pharmacology of novel pyrrolo [2,1-c] [1,4] diazepine-based anticancer agents.
Doctoral thesis , University of London.
|
|
|
Hamid, AA;
Huang, H-C;
Wang, V;
Chen, Y-H;
Feng, F;
Den, R;
Attard, G;
... Sweeney, CJ; + view all
(2021)
Transcriptional profiling of primary prostate tumor in metastatic hormone-sensitive prostate cancer and association with clinical outcomes: correlative analysis of the E3805 CHAARTED trial.
Annals of Oncology
, 32
(9)
pp. 1157-1166.
10.1016/j.annonc.2021.06.003.
|
|
|
Hamilton, N;
Hynds, R;
Gowers, K;
Tait, A;
Butler, C;
Hopper, C;
Burns, A;
... Janes, SM; + view all
(2019)
Using a 3D collagen matrix to deliver respiratory progenitor cells to decellularized trachea in vivo.
Tissue Engineering Part C: Methods
, 25
(2)
pp. 93-102.
10.1089/ten.TEC.2018.0241.
|
|
Hamilton, NJI;
Lee, DDH;
Gowers, KHC;
Butler, CR;
Maughan, EF;
Jevans, B;
Orr, JC;
... Janes, SM; + view all
(2020)
Bioengineered airway epithelial grafts with mucociliary function based on collagen IV- and laminin-containing extracellular matrix scaffolds.
European Respiratory Journal
, 55
, Article 1901200. 10.1183/13993003.01200-2019.
|
|
|
Hammel, P;
Kindler, HL;
Reni, M;
Van Cutsem, E;
Macarulla, T;
Hall, MJ;
Park, JO;
... Golan, T; + view all
(2019)
Health-related quality of life in patients with a germline BRCA mutation and metastatic pancreatic cancer receiving maintenance olaparib.
Annals of Oncology
10.1093/annonc/mdz406.
(In press).
|
|
|
Han, G;
Yang, G;
Hao, D;
Lu, Y;
Thein, K;
Simpson, BS;
Chen, J;
... Wang, L; + view all
(2021)
9p21 loss confers a cold tumor immune microenvironment and primary resistance to immune checkpoint therapy.
Nature Communications
, 12
, Article 5606. 10.1038/s41467-021-25894-9.
|
|
|
Han, H;
Yang, Y;
Jiao, Y;
Qi, H;
Han, Z;
Wang, L;
Dong, L;
... Lei, H; + view all
(2023)
Leverage of nuclease-deficient CasX for preventing pathological angiogenesis.
Molecular Therapy - Nucleic Acids
, 33
pp. 738-748.
10.1016/j.omtn.2023.08.001.
|
|
Han, Haote;
Yang, Yanhui;
Han, Zhuo;
Wang, Luping;
Dong, Lijun;
Qi, Hui;
Liu, Bing;
... Lei, Hetian; + view all
(2023)
NFκB-Mediated Expression of Phosphoinositide 3-Kinase δ Is Critical for Mesenchymal Transition in Retinal Pigment Epithelial Cells.
Cells
, 12
(2)
, Article 207. 10.3390/cells12020207.
|
|
Han, G;
Berhane, S;
Toyoda, H;
Bettinger, D;
Elshaarawy, O;
Chan, AWH;
Kirstein, M;
... Johnson, PJ; + view all
(2019)
Prediction of Survival Among Patients Receiving Transarterial Chemoembolization for Hepatocellular Carcinoma: A Response-Based Approach.
Hepatology
10.1002/hep.31022.
(In press).
|
|
|
Handle, F;
Prekovic, S;
Helsen, C;
Van den Broeck, T;
Smeets, E;
Moris, L;
Eerlings, R;
... Claessens, F; + view all
(2019)
Drivers of AR indifferent anti-androgen resistance in prostate cancer cells.
Scientific Reports
, 9
, Article 137. 10.1038/s41598-019-50220-1.
|
|
|
Harrasser, Micaela;
Gohil, Satyen Harish;
Lau, Hiu;
Della Peruta, Marco;
Muczynski, Vincent;
Patel, Dominic;
Miranda, Elena;
... Nathwani, Amit Chunilal; + view all
(2022)
Inducible localized delivery of an anti-PD-1 scFv enhances anti-tumor activity of ROR1 CAR-T cells in TNBC.
Breast Cancer Research
, 24
(1)
, Article 39. 10.1186/s13058-022-01531-1.
|
|
Harrington, K;
Forster, M;
Dillon, M;
Grove, L;
Adeleke, S;
Chen, S;
Diamond, J;
... Greenberg, J; + view all
(2016)
Patritumab or Placebo Plus Cetuximab and Platinum-Based Therapy in Squamous Cell Carcinoma of the Head and Neck (SCCHN): a Phase 2 Study.
Presented at: ASCO 2016 Annual Meeting: Poster Session, Head and Neck Cancer, Chicago.
|
|
Harrington, KJ;
Bhide, SA;
Forster, MD;
Good, JS;
Gunn, L;
Kong, A;
Melcher, AA;
... Wong, KH; + view all
(2020)
Looking a Gift Horse in the Mouth: Observations on NHS England's Interim Guidance on Pembrolizumab in Head and Neck Squamous Cell Cancer.
Clinical Oncology
, 32
(8)
pp. 490-492.
10.1016/j.clon.2020.05.016.
|
|
|
Hartley, JA;
(2021)
Antibody-drug conjugates (ADCs) delivering pyrrolobenzodiazepine (PBD) dimers for cancer therapy.
Expert Opinion on Biological Therapy
, 21
(7)
pp. 931-943.
10.1080/14712598.2020.1776255.
|
|
Hartley, JA;
Flynn, MJ;
Bingham, JP;
Corbett, S;
Reinert, H;
Tiberghien, A;
Masterson, LA;
... Howard, PW; + view all
(2018)
Pre-clinical pharmacology and mechanism of action of SG3199, the pyrrolobenzodiazepine (PBD) dimer warhead component of antibody-drug conjugate (ADC) payload tesirine.
Scientific Reports
, 8
, Article 10479. 10.1038/s41598-018-28533-4.
|
|
|
Harvey, RD;
Aransay, NR;
Isambert, N;
Lee, J-S;
Arkenau, T;
Vansteenkiste, J;
Dickinson, PA;
... Vishwanathan, K; + view all
(2018)
Effect of multiple-dose osimertinib on the pharmacokinetics of simvastatin and rosuvastatin.
British Journal of Clinical Pharmacology
, 84
(12)
pp. 2877-2888.
10.1111/bcp.13753.
|
|
Hasan, AM Mahedi;
Cremaschi, Paolo;
Wetterskog, Daniel;
Jayaram, Anuradha;
Wong, Stephen Q;
Williams, Scott;
Pasam, Anupama;
... Attard, Gerhardt; + view all
(2023)
Copy number architectures define treatment-mediated selection of lethal prostate cancer clones.
Nature Communications
, 14
, Article 4823. 10.1038/s41467-023-40315-9.
|
|
Hayes, AR;
Mak, IYF;
Evans, N;
Naik, R;
Crawford, A;
Khoo, B;
Grossman, AB;
... Meyer, T; + view all
(2021)
Understanding the Treatment Algorithm of Patients with Metastatic Pancreatic Neuroendocrine Neoplasms: A Single-Institution Retrospective Analysis Comparing Outcomes of Chemotherapy, Molecular Targeted Therapy, and Peptide Receptor Radionuclide Therapy in 255 Patients.
Neuroendocrinology
, 111
(9)
pp. 863-875.
10.1159/000511662.
|
|
Heather, JM;
Ismail, M;
Oakes, T;
Chain, B;
(2017)
High-throughput sequencing of the T-cell receptor repertoire: pitfalls and opportunities.
Brief Bioinform
10.1093/bib/bbw138.
(In press).
|
|
|
Helfen, A;
Rieß, J;
Fehler, O;
Stölting, M;
An, Z;
Kocman, V;
Schnepel, A;
... Eisenblätter, M; + view all
(2022)
In vivo imaging of microenvironmental and anti-PD-L1-mediated dynamics in cancer using S100A8/S100A9 as an imaging biomarker.
Neoplasia
, 28
, Article 100792. 10.1016/j.neo.2022.100792.
|
|
|
Helfen, A;
Roth, J;
Ng, T;
Eisenblaetter, M;
(2017)
In Vivo Imaging of Pro- and Antitumoral Cellular Components of the Tumor Microenvironment.
Journal of Nuclear Medicine
, 59
(2)
pp. 183-188.
10.2967/jnumed.117.198952.
|
|
|
Hellewell, J;
Russell, TW;
SAFER Investigators and Field Study Team, ,;
Crick COVID-19 Consortium, ,;
CMMID COVID-19 working group, ,;
Beale, R;
Kelly, G;
... Kucharski, AJ; + view all
(2021)
Estimating the effectiveness of routine asymptomatic PCR testing at different frequencies for the detection of SARS-CoV-2 infections.
BMC Medicine
, 19
(1)
, Article 106. 10.1186/s12916-021-01982-x.
|
|
|
Hellmann, MD;
Nathanson, T;
Rizvi, H;
Creelan, BC;
Sanchez-Vega, F;
Ahuja, A;
Ni, A;
... Wolchok, JD; + view all
(2018)
Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.
Cancer Cell
, 33
(5)
843-852.e4.
10.1016/j.ccell.2018.03.018.
|
|
|
Herbst, RS;
Arkenau, HT;
Bendell, J;
Arrowsmith, E;
Wermke, M;
Soriano, A;
Penel, N;
... Paz-Ares, L; + view all
(2020)
Phase 1 Expansion Cohort of Ramucirumab Plus Pembrolizumab in Advanced Treatment-Naive NSCLC.
Journal of Thoracic Oncology
, 16
(2)
pp. 289-298.
10.1016/j.jtho.2020.10.004.
|
|
|
Herbst, RS;
Garon, EB;
Kim, D-W;
Cho, BC;
Perez-Gracia, JL;
Han, J-Y;
Arvis, CD;
... Baas, P; + view all
(2020)
Long-Term Outcomes and Retreatment Among Patients With Previously Treated, Programmed Death-Ligand 1Positive, Advanced NonSmall-Cell Lung Cancer in the KEYNOTE-010 Study.
Journal of Clinical Oncology
, 38
(14)
pp. 1580-1590.
10.1200/JCO.19.02446.
|
|
Hernando, B;
Dietzen, M;
Parra, G;
Gil-Barrachina, M;
Pitarch, G;
Mahiques, L;
Valcuende-Cavero, F;
... Martinez-Cadenas, C; + view all
(2021)
The effect of age on the acquisition and selection of cancer driver mutations in sun-exposed normal skin.
Annals of Oncology
, 32
(3)
pp. 412-421.
10.1016/j.annonc.2020.11.023.
|
|
Hertweck, Arnulf;
Vila de Mucha, Maria;
Barber, Paul R;
Dagil, Robert;
Porter, Hayley;
Ramos, Andres;
Lord, Graham M;
(2022)
The TH1 cell lineage-determining transcription factor T-bet suppresses TH2 gene expression by redistributing GATA3 away from TH2 genes.
Nucleic Acids Research
, Article gkac258. 10.1093/nar/gkac258.
(In press).
|
|
Hessey, Sonya;
(2024)
Tumour evolution and immune evasion in lung cancer from diagnosis to death.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Hessey, Sonya;
Fessas, Petros;
Zaccaria, Simone;
Jamal-Hanjani, Mariam;
Swanton, Charles;
(2023)
Insights into the metastatic cascade through research autopsies.
Trends Cancer
10.1016/j.trecan.2023.03.002.
|
|
Hiley, C;
Salem, A;
Batchelor, T;
McDonald, F;
Evison, M;
(2020)
Great debate: surgery versus stereotactic radiotherapy for early-stage non-small cell lung cancer.
Thorax
, 75
(3)
pp. 198-199.
10.1136/thoraxjnl-2019-214014.
|
|
|
Hiley, CT;
Le Quesne, J;
Santis, G;
Sharpe, R;
De Castro, DG;
Middleton, G;
Swanton, C;
(2016)
Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease.
The Lancet
, 388
(10048)
pp. 1002-1011.
10.1016/S0140-6736(16)31340-X.
|
|
|
Hill, William;
Lim, Emilia L.;
Weeden, Clare E.;
Lee, Claudia;
Augustine, Marcellus;
Chen, Kezhong;
Kuan, Feng-Che;
(2023)
Lung adenocarcinoma promotion by air pollutants.
Nature
, 616
pp. 159-167.
10.1038/s41586-023-05874-3.
|
|
Hill, William;
Weeden, Clare E;
Swanton, Charles;
(2024)
Tumor Promoters and Opportunities for Molecular Cancer Prevention.
Cancer Discovery
, 14
(7)
pp. 1154-1160.
10.1158/2159-8290.CD-24-0128.
|
|
Hobor, S;
Al Bakir, M;
Hiley, CT;
Skrzypski, M;
Frankell, AM;
Bakker, B;
Watkins, TBK;
... Clipson, A; + view all
(2024)
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling.
Nature Communications
, 15
, Article 4871. 10.1038/s41467-024-47606-9.
|
|
Hofmann, MR;
Hussain, M;
Dehm, SM;
Beltran, H;
Wyatt, AW;
Halabi, S;
Sweeney, C;
... Sharifi, N; + view all
(2021)
Prostate Cancer Foundation Hormone-Sensitive Prostate Cancer Biomarker Working Group Meeting Summary.
Urology
, 155
pp. 165-171.
10.1016/j.urology.2020.12.021.
|
|
|
Hol, MLF;
Indelicato, DJ;
Slater, O;
Kolb, F;
Hewitt, RJ;
Ong, J;
Becking, AG;
... Suttie, M; + view all
(2023)
Facial deformation following treatment for pediatric head and neck rhabdomyosarcoma; the difference between treatment modalities. Results of a trans-Atlantic, multicenter cross-sectional cohort study.
Pediatric Blood and Cancer
, 70
(8)
, Article e30412. 10.1002/pbc.30412.
|
|
Holme, H;
Gulati, A;
Brough, R;
Fleuren, EDG;
Bajrami, I;
Campbell, J;
Chong, IY;
... Lord, CJ; + view all
(2018)
Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness.
Scientific Reports
, 8
, Article 10614. 10.1038/s41598-018-29043-z.
|
|
|
Hong, DS;
Concin, N;
Vergote, I;
de Bono, JS;
Slomovitz, BM;
Drew, Y;
Arkenau, H-T;
... Coleman, RL; + view all
(2020)
Tisotumab Vedotin in Previously Treated Recurrent or Metastatic Cervical Cancer.
Clinical Cancer Research
, 26
(6)
pp. 1220-1228.
10.1158/1078-0432.CCR-19-2962.
|
|
Hopper, C;
Jerjes, W;
Sultan, A;
Forster, M;
carnell, D;
Simeon, C;
Berg, K;
... Hamdoon, Z; + view all
(2016)
Disulfonated tetraphenyl chlorin (TPCS2a)–induced photochemical internalisation of bleomycin in patients with solid malignancies: A first-in-man phase I dose escalation clinical trial.
The Lancet Oncology
, 17
(9)
pp. 1217-1229.
10.1016/S1470-2045(16)30224-8.
|
|
Hopper, C.;
(2006)
Photodynamic therapy for the treatment of oral cancer.
Doctoral thesis , University of London.
|
|
|
Horlock, Nigel;
(1999)
The Cell Biology Of Basal Cell Carcinoma. Relationship To Histology And Clinical Outcome.
Doctoral thesis (M.D), UCL (University College London).
|
|
Houlihan, CF;
Vora, N;
Byrne, T;
Lewer, D;
Kelly, G;
Heaney, J;
Gandhi, S;
... SAFER Investigators; + view all
(2020)
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers.
The Lancet
, 396
(10246)
e6-e7.
10.1016/S0140-6736(20)31484-7.
|
|
|
Howard, Sasha R;
Freeston, Sarah;
Harrison, Barney;
Izatt, Louise;
Natu, Sonali;
Newbold, Kate;
Pomplun, Sabine;
... Gaze, Mark N; + view all
(2022)
Paediatric differentiated thyroid carcinoma: a UK National Clinical Practice Consensus Guideline.
Endocrine-Related Cancer
, 29
(11)
G1-G33.
10.1530/ERC-22-0035.
|
|
Howie, Alexander J;
Owen-Casey, Mared P;
(2020)
"Green/apple-green birefringence": unfit for purpose?
Kidney International
, 98
(5)
p. 1350.
10.1016/j.kint.2020.07.029.
|
|
Howie, AJ;
(2018)
Genetic studies of focal segmental glomerulosclerosis: a waste of scientific time?
Pediatric Nephrology
10.1007/s00467-018-4161-6.
(In press).
|
|
|
Howlett, Sarah;
Carter, Thomas J;
Shaw, Heather M;
Nathan, Paul D;
(2023)
Tebentafusp: a first-in-class treatment for metastatic uveal melanoma.
Therapeutic Advances in Medical Oncology
, 15
10.1177/17588359231160140.
|
|
Hoyle, AP;
Ali, A;
James, ND;
Cook, A;
Parker, CC;
de Bono, JS;
Attard, G;
... STAMPEDE Investigators; + view all
(2019)
Abiraterone in "High-" and "Low-risk" Metastatic Hormone-sensitive Prostate Cancer.
European Urology
, 76
(6)
pp. 719-728.
10.1016/j.eururo.2019.08.006.
|
|
Hsieh, JJ;
Purdue, MP;
Signoretti, S;
Swanton, C;
Albiges, L;
Schmidinger, M;
Heng, DY;
... Ficarra, V; + view all
(2017)
Renal cell carcinoma.
Nature Reviews Disease Primers
, 3
, Article 17009. 10.1038/nrdp.2017.9.
|
|
|
Hu, Xin;
Estecio, Marcos R;
Chen, Runzhe;
Reuben, Alexandre;
Wang, Linghua;
Fujimoto, Junya;
Carrot-Zhang, Jian;
... Zhang, Jianjun; + view all
(2021)
Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas.
Nature Communications
, 12
, Article 687. 10.1038/s41467-021-20907-z.
|
|
Hu, X;
Fujimoto, J;
Ying, L;
Fukuoka, J;
Ashizawa, K;
Sun, W;
Reuben, A;
... Zhang, J; + view all
(2019)
Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma.
Nature Communications
, 10
, Article 2978. 10.1038/s41467-019-10877-8.
|
|
|
Hudeček, J;
Voorwerk, L;
van Seijen, M;
Nederlof, I;
de Maaker, M;
van den Berg, J;
van de Vijver, KK;
... Peale, F; + view all
(2020)
Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials.
npj Breast Cancer
, 6
, Article 15. 10.1038/s41523-020-0155-1.
|
|
|
Hudson, A;
Chan, C;
Woolf, D;
McWilliam, A;
Hiley, C;
O'Connor, J;
Bayman, N;
... Faivre-Finn, C; + view all
(2018)
Is heterogeneity in stage 3 non-small cell lung cancer obscuring the potential benefits of dose-escalated concurrent chemo-radiotherapy in clinical trials?
Lung Cancer
, 118
pp. 139-147.
10.1016/j.lungcan.2018.02.006.
|
|
Huebner, A;
Dietzen, M;
McGranahan, N;
(2021)
SnapShot: Tumor evolution.
Cell
, 184
(6)
1650-1650.e1.
10.1016/j.cell.2021.02.024.
|
|
Huebner, Ariana;
Black, James RM;
Sarno, Francesca;
Pazo, Roberto;
Juez, Ignacio;
Medina, Laura;
Garcia-Carbonero, Rocio;
... Toledo, Rodrigo A; + view all
(2023)
ACT-Discover: identifying karyotype heterogeneity in pancreatic cancer evolution using ctDNA.
Genome Medicine
, 15
(1)
, Article 27. 10.1186/s13073-023-01171-w.
|
|
|
Hughes, Tessa;
Dijkstra, Krijn K;
Rawlins, Emma L;
Hynds, Robert E;
(2023)
Open questions in human lung organoid research.
Frontiers in Pharmacology
, 13
, Article 1083017. 10.3389/fphar.2022.1083017.
|
|
Hughes, A;
Landers, D;
Arkenau, H-T;
Shah, S;
Stephens, R;
Mahal, A;
Simmons, M;
... Royle, J; + view all
(2016)
Development and Evaluation of a New Technological Way of Engaging Patients and Enhancing Understanding of Drug Tolerability in Early Clinical Development: PROACT.
Advances in Therapy
, 33
(6)
pp. 1012-1024.
10.1007/s12325-016-0335-4.
|
|
Huhalov, A.;
(2004)
Design and cancer-targeting potential of antibody-based molecules directed against carcinoembryonic antigen.
Doctoral thesis , University of London.
|
|
|
Huijskens, SC;
Kroon, PS;
Gaze, MN;
Gandola, L;
Bolle, S;
Supiot, S;
Abakay, CD;
... Janssens, GO; + view all
(2021)
Radical radiotherapy for paediatric solid tumour metastases: An overview of current European protocols and outcomes of a SIOPE multicenter survey.
European Journal of Cancer
, 145
pp. 121-131.
10.1016/j.ejca.2020.12.004.
|
|
Hull, EA;
Livanos, M;
Miranda, E;
Smith, ME;
Chester, KA;
Baker, JR;
(2014)
Homogeneous Bispecifics by Disulfide Bridging.
Bioconjug Chem
, 25
(8)
pp. 1395-1401.
10.1021/bc5002467.
|
|
|
Hung, King L;
Luebeck, Jens;
Dehkordi, Siavash R;
Colón, Caterina I;
Li, Rui;
Wong, Ivy Tsz-Lo;
Coruh, Ceyda;
... Chang, Howard Y; + view all
(2022)
Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH.
Nature Genetics
10.1038/s41588-022-01190-0.
(In press).
|
|
Huntley, C;
Torr, B;
Sud, A;
Rowlands, CF;
Way, R;
Snape, K;
Hanson, H;
... Turnbull, C; + view all
(2023)
Utility of polygenic risk scores in UK cancer screening: a modelling analysis.
The Lancet Oncology
, 24
(6)
pp. 658-668.
10.1016/S1470-2045(23)00156-0.
|
|
|
Hynds, Robert E;
(2022)
Exploiting the potential of lung stem cells to develop pro-regenerative therapies.
Biology Open
, 11
(10)
, Article bio059423. 10.1242/bio.059423.
|
|
Hynds, Robert E;
Huebner, Ariana;
Pearce, David R;
Hil, Mark S;
Akarca, Ayse U;
Moore, David A;
Ward, Sophia;
... Swanton, Charles; + view all
(2024)
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models.
Nature Communications
, 15
, Article 4653. 10.1038/s41467-024-47547-3.
|
|
|
Hynds, Robert E;
Magin, Chelsea M;
Ikonomou, Laertis;
Aschner, Yael;
Beers, Michael F;
Burgess, Janette K;
Heise, Rebecca L;
... Ryan, Amy L; + view all
(2024)
Stem Cells, Cell Therapies and Bioengineering in Lung Biology and Diseases 2023.
American Journal of Physiology: Lung Cellular and Molecular Physiology
10.1152/ajplung.00052.2024.
(In press).
|
|
Hynds, RE;
(2016)
Characterisation of cultured airway basal cells to understand their role in human lung disease.
Doctoral thesis , UCL (University College London).
|
|
Hynds, RE;
Ben Aissa, A;
Gowers, KHC;
Watkins, TBK;
Bosshard-Carter, L;
Rowan, AJ;
Veeriah, S;
... Janes, SM; + view all
(2018)
Expansion of airway basal epithelial cells from primary human non-small cell lung cancer tumors.
International Journal of Cancer
, 143
(1)
pp. 160-166.
10.1002/ijc.31383.
|
|
|
Hynds, RE;
Bonfanti, P;
Janes, SM;
(2017)
Regenerating human epithelia with cultured stem cells: feeder cells, organoids and beyond.
EMBO Molecular Medicine
, 2017
, Article e8213. 10.15252/emmm.201708213.
|
|
|
Hynds, RE;
Butler, CR;
Janes, SM;
Giangreco, A;
(2016)
Expansion of Human Airway Basal Stem Cells and Their Differentiation as 3D Tracheospheres.
Organoids: Methods in Molecular Biology
, 1576
pp. 43-53.
10.1007/7651_2016_5.
|
|
Hynds, RE;
Frese, KK;
Pearce, DR;
Grönroos, E;
Dive, C;
Swanton, C;
(2021)
Progress towards non-small-cell lung cancer models that represent clinical evolutionary trajectories.
Open Biology
, 11
(1)
, Article 200247. 10.1098/rsob.200247.
|
|
|
Hynds, RE;
Giangreco, A;
(2013)
Concise review: the relevance of human stem cell-derived organoid models for epithelial translational medicine.
Stem Cells
, 31
(3)
417 - 422.
10.1002/stem.1290.
|
|
|
Hynds, RE;
Gowers, KHC;
Nigro, E;
Butler, CR;
Bonfanti, P;
Giangreco, A;
Prele, CM;
(2018)
Cross-talk between human airway epithelial cells and 3T3-J2 feeder cells involves partial activation of human MET by murine HGF.
PLoS ONE
, 13
(5)
, Article e0197129. 10.1371/journal.pone.0197129.
|
|
|
Hynds, RE;
Janes, SM;
(2017)
Airway Basal Cell Heterogeneity and Lung Squamous Cell Carcinoma.
Cancer Prevention Research
, 10
(9)
pp. 491-493.
10.1158/1940-6207.CAPR-17-0202.
|
|
Hynds, RE;
Vladimirou, E;
Janes, SM;
(2018)
The secret lives of cancer cell lines.
[Editorial comment].
Disease Models and Mechanisms
, 11
, Article dmm037366. 10.1242/dmm.037366.
|
|
|
Hynds, RE;
Zacharias, WJ;
Nikolić, MZ;
Königshoff, M;
Eickelberg, O;
Gosens, R;
de Coppi, P;
... Lin, QS; + view all
(2021)
National Heart, Lung and Blood Institute and Building Respiratory Epithelium and Tissue for Health (BREATH) Consortium Workshop Report: Moving Forward in Lung Regeneration.
American Journal of Respiratory Cell and Molecular Biology
10.1165/rcmb.2020-0397WS.
(In press).
|
|
I
|
Ikonomou, Laertis;
Magnusson, Mattias;
Dries, Ruben;
Herzog, Erica L;
Hynds, Robert;
Borok, Zea;
Park, Jin-Ah;
... Ryan, Amy L; + view all
(2022)
Stem cells, cell therapies, and bioengineering in lung biology and disease 2021.
American Journal of Physiology: Lung Cellular and Molecular Physiology
, 323
(3)
L342-L354.
10.1152/ajplung.00113.2022.
|
|
Ilson, DH;
Tabernero, J;
Prokharau, A;
Arkenau, H-T;
Ghidini, M;
Fujitani, K;
Van Cutsem, E;
... Shitara, K; + view all
(2019)
Efficacy and Safety of Trifluridine/Tipiracil Treatment in Patients With Metastatic Gastric Cancer Who Had Undergone Gastrectomy: Subgroup Analyses of a Randomized Clinical Trial.
JAMA Oncology
, 6
(1)
, Article e193531.. 10.1001/jamaoncol.2019.3531.
|
|
|
Ingley, KM;
Hughes, D;
Hubank, M;
Lindsay, D;
Plumb, A;
Cox, R;
Chesler, L;
(2021)
Durable response to serial tyrosine kinase inhibitors (TKIs) in an adolescent with metastatic TFG-ROS1 fusion positive Inflammatory Myofibroblastic Tumor (IMT).
Lung Cancer
, 158
pp. 151-155.
10.1016/j.lungcan.2021.05.024.
|
|
Ingley, KM;
Maleddu, A;
Le Grange, F;
Gerrand, C;
Bleyer, A;
Yasmin, E;
Whelan, J;
(2022)
Current approaches to management of bone sarcoma in adolescent and young adult patients.
Pediatric Blood & Cancer
, 69
(2)
, Article e29442. 10.1002/pbc.29442.
|
|
Ingley, KM;
Wan, S;
Vöö, S;
Windsor, R;
Michelagnoli, M;
Saifuddin, A;
Strauss, SJ;
(2021)
Is It Time to Call Time on Bone Marrow Biopsy for Staging Ewing Sarcoma (ES)?
Cancers
, 13
(13)
, Article 3261. 10.3390/cancers13133261.
|
|
|
Irshad, S;
Flores-Borja, F;
Lawler, K;
Monypenny, J;
Evans, R;
Male, V;
Gordon, P;
... Ng, T; + view all
(2017)
RORγt+ innate lymphoid cells promote lymph node metastasis of breast cancers.
Cancer Research
, 77
(5)
pp. 1083-1096.
10.1158/0008-5472.CAN-16-0598.
|
|
Ishii, Yuki;
Orr, Jessica C;
El Mdawar, Marie-Belle;
de Pilger, Denise R Bairros;
Pearce, David R;
Lazarus, Kyren A;
Graham, Rebecca E;
... Hynds, Robert E; + view all
(2025)
Compound screening in human airway basal cells identifies Wnt pathway activators as potential pro-regenerative therapies.
Journal of Cell Science
, 138
(7)
, Article jcs263487. 10.1242/jcs.263487.
|
|
Islam, MS;
Saito, JA;
Emdad, EM;
Ahmed, B;
Islam, MM;
Halim, A;
Hossen, QMM;
... Alam, M; + view all
(2017)
Comparative genomics of two jute species and insight into fibre biogenesis.
Nature Plants
, 3
(2)
, Article 16223. 10.1038/nplants.2016.223.
|
|
|
Ismail, Mazlina;
(2019)
Computational analysis of T cell receptor repertoires in health and disease.
Doctoral thesis (Ph.D), UCL (University College London).
|
J
|
Jahangir, CA;
Page, DB;
Broeckx, G;
Gonzalez, CA;
Burke, C;
Murphy, C;
Reis-Filho, JS;
... Ribeiro, JM; + view all
(2024)
Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer.
The Journal of Pathology
10.1002/path.6238.
(In press).
|
|
Jamal-Hanjani, Mariam;
(2023)
Body composition and lung cancer-associated cachexia in TRACERx.
Nature Medicine
, 29
pp. 846-858.
10.1038/s41591-023-02232-8.
|
|
Jamal-Hanjani, Mariam;
(2023)
High resolution phylogenetic ctDNA tracking predicts relapse risk and metastatic dissemination patterns in early-stage lung cancer.
Nature
(In press).
|
|
Jamal-Hanjani, Mariam;
(2022)
Combining a national research autopsy programme with computational approaches to study cancer evolution and metastasis: an interview with Mariam Jamal-Hanjani.
Communications Biology
, 5
, Article 629. 10.1038/s42003-022-03550-2.
|
|
Jamal-Hanjani, M;
(2015)
The role of intratumour heterogeneity and chromosomal instability in cancer.
Doctoral thesis , UCL (University College London).
|
|
|
Jamal-Hanjani, M;
Thanopoulou, E;
Peggs, KS;
Quezada, SA;
Swanton, C;
(2013)
Tumour heterogeneity and immune-modulation.
Curr Opin Pharmacol
, 13
(4)
497 - 503.
10.1016/j.coph.2013.04.006.
|
|
|
Jamal-Hanjani, M;
Wilson, GA;
McGranahan, N;
Birkbak, NJ;
Watkins, TBK;
Veeriah, S;
Shafi, S;
... Swanton, C; + view all
(2017)
Tracking the Evolution of Non-Small-Cell Lung Cancer.
New England Journal of Medicine
, 376
(22)
pp. 2109-2121.
10.1056/NEJMoa1616288.
|
|
James, ND;
Spears, MR;
Clarke, NW;
Dearnaley, DP;
Mason, MD;
Parker, CC;
Ritchie, AW;
... STAMPEDE Investigators; + view all
(2016)
Failure-Free Survival and Radiotherapy in Patients With Newly Diagnosed Nonmetastatic Prostate Cancer: Data From Patients in the Control Arm of the STAMPEDE Trial.
JAMA Oncology
, 2
(3)
pp. 348-357.
10.1001/jamaoncol.2015.4350.
|
|
James, Nicholas D;
Tannock, Ian;
N'Dow, James;
Feng, Felix;
Gillessen, Silke;
Ali, Syed Adnan;
Trujillo, Blanca;
... Xie, Li-Ping; + view all
(2024)
The Lancet Commission on prostate cancer: planning for the surge in cases.
The Lancet
10.1016/S0140-6736(24)00651-2.
(In press).
|
|
James, ND;
de Bono, JS;
Spears, MR;
Clarke, NW;
Mason, MD;
Dearnaley, DP;
Ritchie, AWS;
... STAMPEDE Investigators; + view all
(2017)
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
The New England Journal of Medicine
, 377
pp. 338-351.
10.1056/NEJMoa1702900.
|
|
James, ND;
Sydes, MR;
Clarke, NW;
Mason, MD;
Dearnaley, DP;
Spears, MR;
Ritchie, AW;
... STAMPEDE investigators; + view all
(2016)
Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial.
Lancet
, 387
(10024)
pp. 1163-1177.
10.1016/S0140-6736(15)01037-5.
|
|
Jamieson, L;
Forster, MD;
Zaki, K;
Mitra, S;
Alli, H;
O’Connor, A;
Patel, A;
... Chambers, PC; + view all
(2020)
Immunotherapy and associated immune-related adverse events at a large UK centre: a mixed methods study.
BMC Cancer
, 20
, Article 743. 10.1186/s12885-020-07215-3.
|
|
|
Jamshidi, A;
Liu, MC;
Klein, EA;
Venn, O;
Hubbell, E;
Beausang, JF;
Gross, S;
... Swanton, C; + view all
(2022)
Evaluation of cell-free DNA approaches for multi-cancer early detection.
Cancer Cell
, 40
(12)
pp. 1537-1549.
10.1016/j.ccell.2022.10.022.
|
|
Janku, Filip;
Choong, Grace M;
Opyrchal, Mateusz;
Dowlati, Afshin;
Hierro, Cinta;
Rodon, Jordi;
Wicki, Andreas;
... Adjei, Alex A; + view all
(2024)
A Phase I Study of the Oral Dual-Acting Pan-PI3K/mTOR Inhibitor Bimiralisib in Patients with Advanced Solid Tumors.
Cancers
, 16
(6)
, Article 1137. 10.3390/cancers16061137.
|
|
Jaureguiberry, G;
De la Dure-Molla, M;
Parry, D;
Quentric, M;
Himmerkus, N;
Koike, T;
Poulter, J;
... Kleta, R; + view all
(2012)
Nephrocalcinosis (enamel renal syndrome) caused by autosomal recessive FAM20A mutations.
Nephron Physiology
, 122
(1-2)
1 - 6.
10.1159/000349989.
|
|
|
Jayakody, SA;
(2012)
Investigating genetic factors underlying hypopituitarism and septo-optic dysplasia in humans.
Doctoral thesis (PhD), UCL (University College London).
|
|
Jayaram, A;
Wingate, A;
Wetterskog, D;
Wheeler, G;
Sternberg, CN;
Jones, R;
Berruti, A;
... Attard, G; + view all
(2021)
Plasma tumor gene conversions after one cycle abiraterone acetate for metastatic castration-resistant prostate cancer: a biomarker analysis of a multi-center international trial.
Annals of Oncology
, 32
(6)
pp. 726-735.
10.1016/j.annonc.2021.03.196.
|
|
Jayaram, Anuradha Krishna;
(2021)
Leveraging circulating tumour DNA to dissect the evolutionary genomic dynamics of drug resistance in prostate cancer.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Jayaram, A;
Wetterskog, K;
Attard, G;
(2018)
Plasma DNA and Metastatic Castration-Resistant Prostate Cancer: The Odyssey to a Clinical Biomarker Test.
Cancer Discovery
, 8
(4)
pp. 392-294.
10.1158/2159-8290.CD-18-0124.
|
|
Jepson, M;
Elliott, D;
Conefrey, C;
Wade, J;
Rooshenas, L;
Wilson, C;
Beard, D;
... OPTIMA prelim study group, .; + view all
(2018)
An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment.
Journal of Clinical Epidemiology
, 99
pp. 75-83.
10.1016/j.jclinepi.2018.02.018.
|
|
|
Jitlal, M;
Khan, I;
Lee, SM;
Hackshaw, A;
(2012)
Stopping clinical trials early for futility: retrospective analysis of several randomised clinical studies.
British Journal of Cancer
, 107
(6)
910 - 917.
10.1038/bjc.2012.344.
|
|
|
Joharatnam-Hogan, N;
Hochhauser, D;
Shiu, K-K;
Rush, H;
Crolley, V;
Wilson, W;
Sharma, A;
... Khan, K; + view all
(2020)
Outcomes of the 2019 novel coronavirus in patients with or without a history of cancer: a multi-centre North London experience.
Therapeutic Advances in Medical Oncology
pp. 1-9.
10.1177/1758835920956803.
|
|
Joharatnam-Hogan, N;
Shiu, KK;
Khan, K;
(2020)
Challenges in the treatment of gastric cancer in the older patient.
Cancer Treatment Reviews
, 85
, Article 101980. 10.1016/j.ctrv.2020.101980.
|
|
|
Joharatnam-Hogan, N;
Wilson, W;
Shiu, KK;
Fusai, GK;
Davidson, B;
Hochhauser, D;
Bridgewater, J;
(2020)
Multimodal Treatment in Metastatic Colorectal Cancer (mCRC) Improves Outcomes—The University College London Hospital (UCLH) Experience.
Cancers
, 12
(12)
, Article 3545. 10.3390/cancers12123545.
|
|
|
Johnston, EW;
Pye, H;
Bonet Carne, E;
Panagiotaki, E;
Patel, D;
Galazi, M;
Heavey, S;
... Punwani, S; + view all
(2016)
INNOVATE: A prospective cohort study combining serum and urinary biomarkers with novel diffusion-weighted magnetic resonance imaging for the prediction and characterization of prostate cancer.
BMC Cancer
, 16
(816)
10.1186/s12885-016-2856-2.
|
|
Jones, AW;
Yao, Z;
Vicencio, JM;
Karkucinska-Wieckowska, A;
Szabadkai, G;
(2012)
PGC-1 family coactivators and cell fate: roles in cancer, neurodegeneration, cardiovascular disease and retrograde mitochondria-nucleus signalling.
Mitochondrion
, 12
(1)
86 - 99.
10.1016/j.mito.2011.09.009.
|
|
|
Jones, GG;
Del Río, IB;
Sari, S;
Sekerim, A;
Young, LC;
Hartig, N;
Areso Zubiaur, I;
... Rodriguez-Viciana, P; + view all
(2019)
SHOC2 phosphatase-dependent RAF dimerization mediates resistance to MEK inhibition in RAS-mutant cancers.
Nature Communications
, 10
(1)
, Article 2532. 10.1038/s41467-019-10367-x.
|
|
|
Jones, M;
Beuron, F;
Borg, A;
Nans, A;
Earl, CP;
Briggs, DC;
Snijders, AP;
... McDonald, NQ; + view all
(2020)
Cryo-EM structures of the XPF-ERCC1 endonuclease reveal how DNA-junction engagement disrupts an auto-inhibited conformation.
Nature Communications
, 11
(1)
, Article 1120. 10.1038/s41467-020-14856-2.
|
|
|
Jones, Morgan Llewellyn;
(2020)
Structural and functional analysis of the human XPF-ERCC1 DNA repair endonuclease.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Jones, OS;
Vassie, C;
Gilson, R;
Lechner, M;
(2017)
Until eradication, awareness.
Lancet Infectious Diseases
, 17
(4)
pp. 368-369.
10.1016/S1473-3099(17)30125-1.
|
|
Jones, RL;
Ratain, MJ;
O'Dwyer, PJ;
Siu, LL;
Jassem, J;
Medioni, J;
DeJonge, M;
... Schwartz, G; + view all
(2019)
Phase II randomised discontinuation trial of brivanib in patients with advanced solid tumours.
European Journal of Cancer
, 120
pp. 132-139.
10.1016/j.ejca.2019.07.024.
|
|
|
Jones, RP;
Psarelli, E-E;
Jackson, R;
Ghaneh, P;
Halloran, CM;
Palmer, DH;
Campbell, F;
... European Study Group for Pancreatic Cancer, .; + view all
(2019)
Patterns of Recurrence After Resection of Pancreatic Ductal Adenocarcinoma: A Secondary Analysis of the ESPAC-4 Randomized Adjuvant Chemotherapy Trial.
JAMA Surgery
10.1001/jamasurg.2019.3337.
(In press).
|
|
Jones, S;
King, PJ;
Antonescu, CN;
Sugiyama, MG;
Bhamra, A;
Surinova, S;
Angelopoulos, N;
... Hochhauser, D; + view all
(2020)
Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.
Scientific Reports
, 10
, Article 663. 10.1038/s41598-019-57153-9.
|
|
|
Joshi, K;
Robert de Massy, M;
Ismail, M;
Reading, JL;
Uddin, I;
Woolston, A;
Hatipoglu, E;
... Chain, B; + view all
(2019)
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Nature Medicine
, 25
pp. 1549-1559.
10.1038/s41591-019-0592-2.
|
|
Jurj, A;
Qian, D;
Calin, GA;
Litchfield, K;
(2022)
At the crossroad between checkpoint blockade and big data analyses: identification of novel biomarkers and potential targets.
Annals of Oncology
, 33
(12)
pp. 1214-1216.
10.1016/j.annonc.2022.10.507.
|
|
Jurmeister, Philipp;
Glöß, Stefanie;
Roller, Renée;
Leitheiser, Maximilian;
Schmid, Simone;
Mochmann, Liliana H;
Payá Capilla, Emma;
... Capper, David; + view all
(2022)
DNA methylation-based classification of sinonasal tumors.
Nature Communications
, 13
(1)
, Article 7148. 10.1038/s41467-022-34815-3.
|
K
|
Kadalayil, L;
Benini, R;
Pallan, L;
O'Beirne, J;
Marelli, L;
Yu, D;
Hackshaw, A;
... Meyer, T; + view all
(2013)
A simple prognostic scoring system for patients receiving transarterial embolisation for hepatocellular cancer.
Ann Oncol
, 24
(10)
pp. 2565-2570.
10.1093/annonc/mdt247.
|
|
|
Kanu, N;
Groenroos, E;
Martinez, P;
Burrell, RA;
Goh, X Yi;
Bartkova, J;
Maya-Mendoza, A;
... Swanton, C; + view all
(2015)
SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair.
Oncogene
, 34
(46)
pp. 5699-5708.
10.1038/onc.2015.24.
|
|
|
Kanu, N;
Penicud, K;
Hristova, MD;
Wong, B;
Raivich, G;
Behrens, A;
(2010)
The ATM cofactor ATMIN protects against oxidative stress and prevents accumulation of DNA damage in the ageing brain.
Journal of Biological Chemistry
, 285
(49)
pp. 38534-38542.
10.1074/jbc.M110.145896.
|
|
|
Kanu, N;
Zhang, T;
Burrell, RA;
Chakraborty, A;
Cronshaw, J;
DaCosta, C;
Grönroos, E;
... Behrens, A; + view all
(2015)
RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress.
Oncogene
, 35
(30)
pp. 4009-4019.
10.1038/onc.2015.427.
|
|
|
Kanu, Nnennaya;
Lu, Wei-Ting;
Swanton, Charles;
Bartek, Jiri;
(2025)
TRACERx analysis identifies a role for FAT1 in regulating chromosomal instability and whole-genome doubling via Hippo signalling.
Nature Cell Biology
, 27
(1)
pp. 154-168.
10.1038/s41556-024-01558-w.
|
|
|
Kanu, N;
Cerone, MA;
Goh, G;
Zalmas, L-P;
Bartkova, J;
Dietzen, M;
McGranahan, N;
... Swanton, C; + view all
(2016)
DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer.
Genome Biology
, 17
, Article 185. 10.1186/s13059-016-1042-9.
|
|
|
Kapriniotis, K;
Bania, A;
Lampridis, S;
Geropoulos, G;
Mitsos, S;
Monk, F;
Moore, DA;
(2021)
Metastatic mandibular ameloblastoma of the lung ten years after primary resection: A rare case report.
Monaldi Archives for Chest Disease
, 91
(2)
, Article 1643. 10.4081/monaldi.2021.1643.
|
|
Karamchandani, Searan;
Sahovaler, Axel;
Crosbie-Jones, Elizabeth;
McGurk, Mark;
Thavaraj, Selvam;
Alibhai, Mustansir;
Wan, Simon;
... Schilling, Clare; + view all
(2024)
Incidence and predictive factors for positive non-sentinel lymph nodes in completion neck dissection following a positive sentinel node biopsy in early oral cancer.
Oral Oncology
, 159
, Article 107081. 10.1016/j.oraloncology.2024.107081.
|
|
Karamched, Saketh R;
Gorup, Dunja;
Tolomeo, Daniele;
Brooks, Lucy J;
Gong, Ting;
Jørgensen, Andreas Christ Sølvsten;
Hill, Ciaran Scott;
... Lythgoe, Mark F; + view all
(2025)
Detecting glioblastoma infiltration beyond conventional imaging tumour margins using MTE-NODDI.
Imaging Neuroscience
, 3
pp. 1-14.
10.1162/imag_a_00472.
|
|
|
Karasaki, T;
Moore, DA;
Veeriah, S;
Naceur-Lombardelli, C;
Toncheva, A;
Magno, N;
Ward, S;
... Jamal-Hanjani, M; + view all
(2023)
Evolutionary characterization of lung adenocarcinoma morphology in TRACERx.
Nature Medicine
, 29
pp. 833-845.
10.1038/s41591-023-02230-w.
|
|
Karasaki, Takahiro;
Moore, David A;
Jamal-Hanjani, Mariam;
(2023)
Clinicogenomic landscape of morphological evolution in lung adenocarcinoma.
Nature Medicine
, 29
(4)
pp. 795-796.
10.1038/s41591-023-02231-9.
|
|
Karpathakis, A;
(2015)
Molecular profiling of gastrointestinal neuroendocrine tumours.
Doctoral thesis , UCL (University College London).
|
|
Karpathakis, A;
Dibra, H;
Pipinikas, C;
Feber, A;
Morris, T;
Francis, JM;
Oukrif, D;
... Thirlwell, C; + view all
(2017)
Progressive epigenetic dysregulation in neuroendocrine tumour liver metastasis.
Endocrine-Related Cancer
, 24
(2)
L21-L25.
10.1530/ERC-16-0419.
|
|
Karpathakis, A;
Pericleous, M;
Luong, TV;
Khoo, B;
Thirlwell, C;
Toumpanakis, C;
Caplin, ME;
(2013)
Pancreatic adenocarcinoma in a patient with multiple endocrine neoplasia 1 syndrome.
Pancreas
, 42
(4)
725 - 726.
10.1097/MPA.0b013e31827591e9.
|
|
|
Kaufmann, Tom L;
Petkovic, Marina;
Watkins, Thomas BK;
Colliver, Emma C;
Laskina, Sofya;
Thapa, Nisha;
Minussi, Darlan C;
... Schwarz, Roland F; + view all
(2022)
MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution.
Genome Biology volume
, 23
, Article 241. 10.1186/s13059-022-02794-9.
|
|
Keane, Lily;
Antignano, Ignazio;
Riechers, Sean-Patrick;
Zollinger, Raphael;
Dumas, Anaelle A;
Offermann, Nina;
Bernis, Maria E;
... Capasso, Melania; + view all
(2021)
mTOR-dependent translation amplifies microglia priming in aging mice.
Journal of Clinical Investigation
, 131
(1)
, Article e132727. 10.1172/JCI132727.
|
|
Kelley, RK;
Miksad, R;
Cicin, I;
Chen, Y;
Klümpen, H-J;
Kim, S;
Lin, Z-Z;
... Abou-Alfa, GK; + view all
(2021)
Efficacy and safety of cabozantinib for patients with advanced hepatocellular carcinoma based on albumin-bilirubin grade.
British Journal of Cancer
10.1038/s41416-021-01532-5.
(In press).
|
|
|
Kelley, RK;
Meyer, T;
Rimassa, L;
Merle, P;
Park, J-W;
Yau, T;
Chan, SL;
... Abou-Alfa, GK; + view all
(2020)
Serum Alpha-fetoprotein Levels and Clinical Outcomes in the Phase III CELESTIAL Study of Cabozantinib versus Placebo in Patients with Advanced Hepatocellular Carcinoma.
Clinical Cancer Research
, 26
(18)
pp. 4795-4804.
10.1158/1078-0432.CCR-19-3884.
|
|
Kelley, RK;
Ryoo, B-Y;
Merle, P;
Park, J-W;
Bolondi, L;
Chan, SL;
Lim, HY;
... Abou-Alfa, GK; + view all
(2020)
Second-line cabozantinib after sorafenib treatment for advanced hepatocellular carcinoma: a subgroup analysis of the phase 3 CELESTIAL trial.
ESMO Open
, 5
(4)
, Article e000714. 10.1136/esmoopen-2020-000714.
|
|
|
Kelly, SM;
Effeney, R;
Gaze, MN;
Bernier-Chastagner, V;
Blondeel, A;
Clementel, E;
Corning, C;
... Mandeville, HC; + view all
(2022)
QUARTET: A SIOP Europe project for quality and excellence in radiotherapy and imaging for children and adolescents with cancer.
European Journal of Cancer
, 172
pp. 209-220.
10.1016/j.ejca.2022.05.037.
|
|
Kelly, SM;
Turcas, A;
Corning, C;
Bailey, S;
Cañete, A;
Clementel, E;
di Cataldo, A;
... Mandeville, H; + view all
(2023)
Radiotherapy quality assurance in paediatric clinical trials: first report from six QUARTET-affiliated trials.
Radiotherapy and Oncology
, 182
, Article 109549. 10.1016/j.radonc.2023.109549.
|
|
Kemp, SA;
Collier, DA;
Datir, RP;
Ferreira, IATM;
Gayed, S;
Jahun, A;
Hosmillo, M;
... Gupta, RK; + view all
(2021)
SARS-CoV-2 evolution during treatment of chronic infection.
Nature
, 592
pp. 277-282.
10.1038/s41586-021-03291-y.
|
|
Keshwani, K;
Boterberg, T;
Dieckmann, K;
Janssens, GO;
Laprie, A;
Timmermann, B;
Gaze, MN;
(2023)
Radical skeletal metastatic site irradiation in highrisk neuroblastoma: systematic review and proposal for a randomised trial: a report from the SIOPEN Radiotherapy Committee.
Journal of Cancer Metastasis and Treatment
, 9
(1)
10.20517/2394-4722.2022.32.
|
|
Khalil, AME;
Memon, FA;
Tabish, TA;
Fenton, B;
Salmon, D;
Zhang, S;
Butler, D;
(2021)
Performance Evaluation of Porous Graphene as Filter Media for the Removal of Pharmaceutical/Emerging Contaminants from Water and Wastewater.
Nanomaterials
, 11
(1)
, Article 79. 10.3390/nano11010079.
|
|
|
Khalil, AME;
Memon, FA;
Tabish, TA;
Salmon, D;
Zhang, S;
Butler, D;
(2020)
Nanostructured porous graphene for efficient removal of emerging contaminants (pharmaceuticals) from water.
Chemical Engineering Journal
, 398
, Article 125440. 10.1016/j.cej.2020.125440.
|
|
Khan, I;
Morris, S;
Hackshaw, A;
Lee, SM;
(2015)
Cost-effectiveness of first-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy.
BMJ Open
, 5
(7)
, Article e006733. 10.1136/bmjopen-2014-006733.
|
|
|
Khan, MS;
(2013)
Circulating Tumour Cells and Biomarkers in Neuroendocrine Tumours.
Doctoral thesis , UCL (University College London).
|
|
Kiakos, K;
Englinger, B;
Yanow, SK;
Wernitznig, D;
Jakupec, MA;
Berger, W;
Keppler, BK;
... Patil, PC; + view all
(2018)
Design, synthesis, nuclear localization, and biological activity of a fluorescent duocarmycin analog, HxTfA.
Bioorganic & Medicinal Chemistry Letters
, 28
(8)
pp. 1342-1347.
10.1016/j.bmcl.2018.03.016.
|
|
Kiakos, K.;
(2007)
Molecular and cellular pharmacology of novel chiral and achiral CC-1065/duocarmycin analogues.
Doctoral thesis , University of London.
|
|
|
Kidd, AC;
Skrzypski, M;
Jamal-Hanjani, M;
Blyth, KG;
(2019)
Cancer cachexia in thoracic malignancy: a narrative review.
Current Opinion in Supportive and Palliative Care
, 13
(4)
pp. 316-322.
10.1097/SPC.0000000000000465.
|
|
Kim, J.B.;
(2005)
Development of a fully "humanized" xenograft model of breast cancer.
Doctoral thesis , University of London.
|
|
|
Kim, RD;
Sarker, D;
Meyer, T;
Yau, T;
Macarulla, T;
Park, J-W;
Choo, SP;
... Kang, Y-K; + view all
(2019)
First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant Fibroblast Growth Factor 19 Signaling as a Driver Event in Hepatocellular Carcinoma.
Cancer Discovery
, 9
(12)
pp. 1696-1707.
10.1158/2159-8290.CD-19-0555.
|
|
Kim, YJ;
Sheu, KM;
Tsoi, J;
Abril-Rodriguez, G;
Medina, E;
Grasso, CS;
Torrejon, DY;
... Ribas, A; + view all
(2021)
Melanoma dedifferentiation induced by IFN-γ epigenetic remodeling in response to anti–PD-1 therapy.
The Journal of Clinical Investigation
, 131
(12)
, Article e145859. 10.1172/JCI145859.
|
|
|
Kindler, Hedy L;
Hammel, Pascal;
Reni, Michele;
Van Cutsem, Eric;
Macarulla, Teresa;
Hall, Michael J;
Park, Joon Oh;
... Golan, Talia; + view all
(2022)
Overall Survival Results From the POLO Trial: A Phase III Study of Active Maintenance Olaparib Versus Placebo for Germline BRCA-Mutated Metastatic Pancreatic Cancer.
Journal of Clinical Oncology
, 40
(34)
pp. 3929-3939.
10.1200/JCO.21.01604.
|
|
King, J;
Palmer, DH;
Johnson, P;
Ross, P;
Hubner, RA;
Sumpter, K;
Darby, S;
... Meyer, T; + view all
(2017)
Sorafenib for the Treatment of Advanced Hepatocellular Cancer – a UK Audit.
Clinical Oncology
, 29
(4)
pp. 256-262.
10.1016/j.clon.2016.11.012.
|
|
Kinna, A;
Tolner, B;
Rota, EM;
Titchener-Hooker, N;
Nesbeth, D;
Chester, K;
(2016)
IMAC capture of recombinant protein from unclarified mammalian cell feed streams.
Biotechnology and Bioengineering
, 113
(1)
pp. 130-140.
10.1002/bit.25705.
|
|
|
Kinna, AW;
(2017)
Improved production and purification of recombinant proteins from mammalian expression systems.
Doctoral thesis , UCL (University College London).
|
|
|
Kleftogiannis, D;
Punta, M;
Jayaram, A;
Sandhu, S;
Wong, SQ;
Gasi Tandefelt, D;
Conteduca, V;
... Lise, S; + view all
(2019)
Identification of single nucleotide variants using position-specific error estimation in deep sequencing data.
BMC Med Genomics
, 12
(1)
, Article 115. 10.1186/s12920-019-0557-9.
|
|
|
Klein, EA;
Richards, D;
Cohn, A;
Tummala, M;
Lapham, R;
Cosgrove, D;
Chung, G;
... Liu, MC; + view all
(2021)
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set.
Annals of Oncology
10.1016/j.annonc.2021.05.806.
(In press).
|
|
|
Kobialka, Piotr;
Llena, Judith;
Deleyto-Seldas, Nerea;
Munar-Gelabert, MARGALIDA;
Dengra, JOSE A;
Villacampa, ALBA;
Albinyà-Pedrós, Alba;
... Graupera, Mariona; + view all
(2023)
PI3K-C2β limits mTORC1 signaling and angiogenic growth.
Science Signaling
, 16
(813)
, Article eadg19. 10.1126/scisignal.adg1913.
|
|
Koch, C;
Schwing, AM;
Herrmann, E;
Borner, M;
Diaz-Rubio, E;
Dotan, E;
Feliu, J;
... Trojan, J; + view all
(2018)
Bevacizumab-based first-line chemotherapy in elderly patients with metastatic colorectal cancer: an individual patient data based meta-analysis.
Oncotarget
, 9
(12)
pp. 10272-10283.
10.18632/oncotarget.23475.
|
|
|
Kodali, Sudha;
Kulik, Laura;
D'Allessio, Antonio;
De Martin, Eleonora;
Hakeem, Abdul Rahman;
Lewinska, Monica;
Lindsey, Stacie;
... Sapisochin, Gonzalo; + view all
(2025)
The 2024 ILTS-ILCA consensus recommendations for liver transplantation for hepatocellular carcinoma and intrahepatic cholangiocarcinoma.
Liver Transplantation
10.1097/LVT.0000000000000589.
(In press).
|
|
Kogelberg, H;
Miranda, E;
Burnet, J;
Ellison, D;
Tolner, B;
Foster, J;
Picón, C;
... Chester, K; + view all
(2013)
Generation and Characterization of a Diabody Targeting the αvβ6 Integrin.
PLoS One
, 8
(9)
, Article e73260. 10.1371/journal.pone.0073260.
|
|
|
Kok, K;
Nock, GE;
Verrall, EA;
Mitchell, MP;
Hommes, DW;
Peppelenbosch, MP;
Vanhaesebroeck, B;
(2009)
Regulation of p110δ PI 3-Kinase Gene Expression.
PLoS One
, 4
(4)
, Article e5145. 10.1371/journal.pone.0005145.
|
|
|
Konecny, G;
Kristeleit, RS;
(2016)
PARP inhibitors for BRCA1/2-mutated and sporadic ovarian cancer: current practice and future directions.
British Journal of Cancer
, 115
pp. 1157-1173.
10.1038/bjc.2016.311.
|
|
|
Kong, A;
Good, J;
Kirkham, A;
Savage, J;
Mant, R;
Llewellyn, L;
Parish, J;
... Mehanna, H; + view all
(2020)
Phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: the WISTERIA trial protocol.
BMJ Open
, 10
(3)
, Article e033009. 10.1136/bmjopen-2019-033009.
|
|
|
Kopetz, S;
Grothey, A;
Yaeger, R;
Van Cutsem, E;
Desai, J;
Yoshino, T;
Wasan, H;
... Tabernero, J; + view all
(2019)
Encorafenib, Binimetinib, and Cetuximab in BRAF V600E-Mutated Colorectal Cancer.
The New England Journal of Medicine
, 381
(17)
pp. 1632-1643.
10.1056/NEJMoa1908075.
|
|
Kos, Z;
Roblin, E;
Kim, RS;
Michiels, S;
Gallas, BD;
Chen, W;
van de Vijver, KK;
... International Immuno-Oncology Biomarker Working Group; + view all
(2020)
Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer.
NPJ Breast Cancer
, 6
, Article 17. 10.1038/s41523-020-0156-0.
|
|
|
Kotsiou, E;
Hou, TZ;
Robinson, J;
Varsani, S;
Oakes, T;
Becker, PD;
Patel, S;
... Newton, K; + view all
(2020)
Next generation clonal neoantigen targeting T cells, generated using the PELEUS (TM) bioinformatics platform and the VELOS (TM) manufacturing method show superior reactivity and phenotypic characteristics than classical TIL products.
Presented at: AACR Annual Meeting, Philadelphia, PA, USA.
|
|
Kotwinski, PJ;
Smith, G;
Cooper, J;
Sanders, J;
Ma, L;
Teis, A;
Kotwinski, D;
... Breast cancer Early disease: Toxicity from Therapy with Epirubic; + view all
(2016)
Body Surface Area and Baseline Blood Pressure Predict Subclinical Anthracycline Cardiotoxicity in Women Treated for Early Breast Cancer.
PLOS One
, 11
(12)
, Article e0165262. 10.1371/journal.pone.0165262.
|
|
|
Kristeleit, R;
Moreno, V;
Boni, V;
Guerra, EM;
Kahatt, C;
Romero, I;
Calvo, E;
... Forster, M; + view all
(2021)
Doxorubicin plus lurbinectedin in patients with advanced endometrial cancer: Results from an expanded phase i study.
International Journal of Gynecological Cancer
, 31
(11)
pp. 1428-1436.
10.1136/ijgc-2021-002881.
|
|
Kristeleit, R;
Davidenko, I;
Shirinkin, V;
El-Khouly, F;
Bondarenko, I;
Goodheart, MJ;
Gorbunova, V;
... Schilder, RJ; + view all
(2017)
A randomised, open-label, phase 2 study of the IDO1 inhibitor epacadostat (INCB024360) versus tamoxifen as therapy for biochemically recurrent (CA-125 relapse)-only epithelial ovarian cancer, primary peritoneal carcinoma, or fallopian tube cancer.
Gynecologic Oncology
, 146
(3)
pp. 484-490.
10.1016/j.ygyno.2017.07.005.
|
|
Kristeleit, R;
Evans, J;
Molife, LR;
Tunariu, N;
Shaw, H;
Slater, S;
Haris, NRM;
... Lopez, J; + view all
(2020)
Phase 1/2a trial of intravenous BAL101553, a novel controller of the spindle assembly checkpoint, in advanced solid tumours.
British Journal of Cancer
10.1038/s41416-020-1010-8.
(In press).
|
|
|
Kristeleit, R;
Shapiro, GI;
Burris, HA;
Oza, AM;
LoRusso, P;
Patel, MR;
Domchek, SM;
... Shapira-Frommer, R; + view all
(2017)
A Phase I-II Study of the Oral PARP Inhibitor Rucaparib in Patients with Germline BRCA1/2-Mutated Ovarian Carcinoma or Other Solid Tumors.
Clinical Cancer Research
, 23
(15)
pp. 4095-4106.
10.1158/1078-0432.CCR-16-2796.
|
|
Kristeleit, RS;
Lorusso, D;
Oaknin, A;
Safra, T;
Swisher, EM;
Bondarenko, IM;
Huzarski, T;
... Oza, A; + view all
(2017)
988TiP: ARIEL4: An international, randomised phase 3 study of the PARP inhibitor rucaparib vs chemotherapy for the treatment of BRCA-mutated, relapsed, high-grade ovarian cancer.
Presented at: 42nd ESMO Congress (ESMO 2017), Madrid, Spain.
|
|
Kristeleit, RS;
Miller, R;
Sellers, L;
Brown, N;
Devlin, M;
Woo, K;
Boyd, A;
... Linch, M; + view all
(2017)
A first-in-human Phase I/II, dose escalation, pharmacokinetic study to assess safety and tolerability of VAL201 in advanced prostate cancer.
Presented at: 15th International Congress on Targeted Anticancer Therapies (TAT 2017), Paris, France.
|
|
Kristeleit, RS;
Miller, RE;
Kohn, EC;
(2016)
Gynecologic Cancers: Emerging Novel Strategies for Targeting DNA Repair Deficiency.
American Society of Clinical Oncology Educational Book
, 2016
10.14694/EDBK_159086.
|
|
|
Kristeleit, RS;
Oaknin, A;
Ray-Coquard, I;
Leary, A;
Balmaña, J;
Drew, Y;
Oza, AM;
... McNeish, IA; + view all
(2019)
Antitumor activity of the poly(ADP-ribose) polymerase inhibitor rucaparib as monotherapy in patients with platinum-sensitive, relapsed, BRCA-mutated, high-grade ovarian cancer, and an update on safety.
International Journal of Gynecological Cancer
, 29
(9)
pp. 1396-1404.
10.1136/ijgc-2019-000623.
|
|
|
Kristensen, NP;
Heeke, C;
Tvingsholm, SA;
Borch, A;
Draghi, A;
Crowther, MD;
Carri, I;
... Hadrup, SR; + view all
(2021)
Neoantigen-reactive CD8+ T cells affect clinical outcome of adoptive transfer with tumor-infiltrating lymphocytes in melanoma.
Journal of Clinical Investigation
10.1172/JCI150535.
(In press).
|
|
|
Krol, I;
Castro-Giner, F;
Maurer, M;
Gkountela, S;
Szczerba, BM;
Scherrer, R;
Coleman, N;
... Aceto, N; + view all
(2018)
Detection of circulating tumour cell clusters in human glioblastoma.
British Journal of Cancer
, 119
pp. 487-491.
10.1038/s41416-018-0186-7.
|
|
|
Kudo, Masatoshi;
Finn, Richard S;
Ikeda, Masafumi;
Sung, Max W;
Baron, Ari D;
Okusaka, Takuji;
Kobayashi, Masahiro;
... Llovet, Josep M; + view all
(2023)
A Phase 1b Study of Lenvatinib plus Pembrolizumab in Patients with Unresectable Hepatocellular Carcinoma: Extended Analysis of Study 116.
Liver Cancer
10.1159/000535154.
(In press).
|
|
Kularatne, B;
Arora, R;
Elshstein, G;
Guppy, N;
Kirkwood, A;
Meyer, T;
Kristeleit, RS;
(2016)
Immunohistochemistry (IHC) evaluation of a novel 4-protein prognostic and predictive biomarker panel in endometrial cancer (EC).
In:
Abstract Book of the 41st ESMO Congress (ESMO 2016), 7-11 October 2016, Copenhagen, Denmar.
Oxford University Press (OUP): Policy A1
|
|
Kurzrock, R;
Bowles, DW;
Kang, H;
Meric-Bernstam, F;
Hainsworth, J;
Spigel, DR;
Bose, R;
... Swanton, C; + view all
(2020)
Targeted therapy for advanced salivary gland carcinoma based on molecular profiling: results from MyPathway, a phase IIa multiple basket study.
Annals of Oncology
, 31
(3)
pp. 412-421.
10.1016/j.annonc.2019.11.018.
|
|
L
|
Labeur, TA;
Berhane, S;
Edeline, J;
Blanc, J-F;
Bettinger, D;
Meyer, T;
Van Vugt, JLA;
... Johnson, PJ; + view all
(2020)
Improved survival prediction and comparison of prognostic models for patients with hepatocellular carcinoma treated with sorafenib.
Liver International
, 40
(1)
pp. 215-228.
10.1111/liv.14270.
|
|
|
Ladenstein, R;
Pötschger, U;
Valteau-couanet, D;
Luksch, R;
Castel, V;
Ash, S;
Laureys, G;
... Lode, HN; + view all
(2020)
Investigation of the Role of Dinutuximab Beta-Based Immunotherapy in the SIOPEN High-Risk Neuroblastoma 1 Trial (HR-NBL1).
Cancers
, 12
(2)
, Article 309. 10.3390/cancers12020309.
|
|
Lai, AG;
Pasea, L;
Banerjee, A;
Hall, G;
Denaxas, S;
Chang, WH;
Katsoulis, M;
... Hemingway, H; + view all
(2020)
Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study.
BMJ Open
, 10
(11)
, Article e043828. 10.1136/bmjopen-2020-043828.
|
|
|
Lalani, Zubair;
Chu, Gillian;
Hsu, Silas;
Kagawa, Shaw;
Xiang, Michael;
Zaccaria, Simone;
El-Kebir, Mohammed;
(2022)
CNAViz: An interactive webtool for user-guided segmentation of tumor DNA sequencing data.
PLoS Computational Biology
, 18
(10)
, Article e1010614. 10.1371/journal.pcbi.1010614.
(In press).
|
|
Lamarca, A;
Walter, T;
Pavel, M;
Borbath, I;
Freis, P;
Nuñez, B;
Childs, A;
... Barriuso, J; + view all
(2017)
Design and Validation of the GI-NEC Score to Prognosticate Overall Survival in Patients With High-Grade Gastrointestinal Neuroendocrine Carcinomas.
Journal of the National Cancer Institute
, 109
(5)
10.1093/jnci/djw277.
|
|
Lampada, A;
(2016)
Targeting autophagy in colorectal cancer.
Doctoral thesis , UCL (University College London).
|
|
Lampada, A;
O'Prey, J;
Szabadkai, G;
Ryan, KM;
Hochhauser, D;
Salomoni, P;
(2017)
mTORC1-independent autophagy regulates receptor tyrosine kinase phosphorylation in colorectal cancer cells via an mTORC2-mediated mechanism.
Cell Death and Differentiation
, 24
(6)
pp. 1045-1062.
10.1038/cdd.2017.41.
|
|
Lange, Joshua T;
Rose, John C;
Chen, Celine Y;
Pichugin, Yuriy;
Xie, Liangqi;
Tang, Jun;
Hung, King L;
... Mischel, Paul S; + view all
(2022)
The evolutionary dynamics of extrachromosomal DNA in human cancers.
Nature Genetics
10.1038/s41588-022-01177-x.
(In press).
|
|
Lankester, K.J.;
(2005)
Magnetic resonance imaging and the development of vascular targeted treatments for cancer.
Doctoral thesis , University of London.
|
|
|
Laskaratos, F-M;
Rombouts, K;
Caplin, M;
Toumpanakis, C;
Thirlwell, C;
Mandair, D;
(2017)
Neuroendocrine tumors and fibrosis: An unsolved mystery?
Cancer
, 123
(24)
pp. 4770-4790.
10.1002/cncr.31079.
|
|
Laskaratos, F-M;
Walker, M;
Naik, K;
Maragkoudakis, E;
Oikonomopoulos, N;
Grant, L;
Meyer, T;
... Toumpanakis, C; + view all
(2016)
Predictive factors of antiproliferative activity of octreotide LAR as first-line therapy for advanced neuroendocrine tumours.
British Journal of Cancer
, 115
(11)
pp. 1321-1327.
10.1038/bjc.2016.349.
|
|
Lau, Chun Hang;
Rouhani, Maral J;
Maughan, Elizabeth F;
Orr, Jessica C;
Kolluri, Krishna K;
Pearce, David R;
Haughey, Elizabeth K;
... Hynds, Robert E; + view all
(2024)
Lentiviral expression of wild-type LAMA3A restores cell adhesion in airway basal cells from children with epidermolysis bullosa.
Molecular Therapy
10.1016/j.ymthe.2024.02.032.
(In press).
|
|
Lau, Evelyn Keet Wai;
(2021)
Genomic and epigenomic impact of oncogenic mutation in the PIK3CA gene.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Lauder, Sarah N;
Smart, Kathryn;
Bart, Valentina MT;
Pires, Ana;
Scott, Jake;
Milutinovic, Stefan;
Godkin, Andrew;
... Gallimore, Awen; + view all
(2022)
Treg-driven tumour control by PI3Kδ inhibition limits myeloid-derived suppressor cell expansion.
British Journal of Cancer
10.1038/s41416-022-01917-0.
(In press).
|
|
Lauder, SN;
Smart, K;
Kersemans, V;
Allen, D;
Scott, J;
Pires, A;
Milutinovic, S;
... Gallimore, A; + view all
(2020)
Enhanced antitumor immunity through sequential targeting of PI3Kδ and LAG3.
Journal for Immuno Therapy of Cancer
, 8
(2)
, Article e000693. 10.1136/jitc-2020-000693.
|
|
|
Lauder, SN;
Vanhaesebroeck, B;
Gallimore, A;
(2021)
Sequential targeting of PI3Kδ and LAG3 as an effective anti-cancer approach.
British Journal of Cancer
10.1038/s41416-021-01285-1.
(In press).
|
|
|
Laurent, P-A;
Hechler, B;
Solinhac, R;
Ragab, A;
Cabou, C;
Anquetil, T;
Severin, S;
... Gratacap, M-P; + view all
(2018)
Impact of PI3K (Phosphoinositide 3-Kinase Alpha) Inhibition on Hemostasis and Thrombosis.
Arteriosclerosis, Thrombosis, and Vascular Biology
, 38
(9)
pp. 2041-2053.
10.1161/ATVBAHA.118.311410.
|
|
Lawler, K;
Papouli, E;
Naceur-Lombardelli, C;
Mera, A;
Ougham, K;
Tutt, A;
Kimbung, S;
... Purushotham, A; + view all
(2017)
Gene expression modules in primary breast cancers as risk factors for organotropic patterns of first metastatic spread: a case control study.
Breast Cancer Research
, 19
, Article 113. 10.1186/s13058-017-0881-y.
|
|
|
Lawler, M;
Alsina, D;
Adams, RA;
Anderson, AS;
Brown, G;
Fearnhead, NS;
Fenwick, SW;
... Tomlinson, I; + view all
(2018)
Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer.
GUT
, 67
(1)
pp. 179-193.
10.1136/gutjnl-2017-315333.
|
|
|
Lawson, C;
Vicencio, JM;
Yellon, DM;
Davidson, SM;
(2016)
Microvesicles and exosomes: new players in metabolic and cardiovascular disease.
Journal of Endocrinology
, 228
(2)
R57-R71.
10.1530/JOE-15-0201.
|
|
Leary, A.;
(2006)
Quality of life in patients receiving platinum based chemotherapy for advanced non-small cell lung cancer.
Doctoral thesis , University of London.
|
|
|
Lecat, Catherine SY;
Rodriguez-Justo, Manuel;
Patel, Dominic;
Yong, Kwee;
Papanikolaou, Xenofon;
(2021)
A rare case of relapsed multiple myeloma with aberrant T-cell antigen expression and skin plasmacytomas.
eJHaem
, 2
(2)
pp. 301-302.
10.1002/jha2.172.
|
|
Lechner, M;
Takahashi, Y;
Turri-Zanoni, M;
Liu, J;
Counsell, N;
Hermsen, M;
Kaur, RP;
... Hanna, EY; + view all
(2022)
Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma.
European Journal of Cancer
, 162
pp. 221-236.
10.1016/j.ejca.2021.09.046.
|
|
Lechner, M;
(2014)
Exploring epigenetics.
International Innovation
(167)
pp. 108-110.
|
|
|
Lechner, M;
(2012)
Genomic and Epigenomic Analysis of HPV positive and HPV negative Head and Neck Squamous Cell Cancer.
Doctoral thesis , UCL (University College London).
|
|
|
Lechner, M;
Breeze, CE;
O'Mahony, JF;
Masterson, L;
(2019)
Early detection of HPV-associated oropharyngeal cancer.
[Letter].
Lancet
, 393
(10186)
p. 2123.
10.1016/S0140-6736(19)30227-2.
|
|
Lechner, M;
Chakravarthy, AR;
Walter, V;
Masterson, L;
Feber, A;
Jay, A;
Weinberger, PM;
... Fenton, TR; + view all
(2018)
Frequent HPV-independent p16/INK4A overexpression in head and neck cancer.
Oral Oncology
, 83
pp. 32-37.
10.1016/j.oraloncology.2018.06.006.
|
|
Lechner, M;
Fenton, T;
West, J;
Wilson, G;
Feber, A;
Henderson, S;
Thirlwell, C;
... Beck, S; + view all
(2013)
Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma.
Genome Medicine
, 5
(2)
p. 15.
10.1186/gm419.
|
|
|
Lechner, M;
Frampton, G;
Fenton, T;
Feber, A;
Palmer, G;
Jay, A;
Pillay, N;
... Boshoff, C; + view all
(2013)
Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors.
Genome Medicine
, 5
, Article 49. 10.1186/gm453.
|
|
|
Lechner, M;
Jones, OS;
Breeze, CE;
Gilson, R;
(2019)
Gender-neutral HPV vaccination in the UK, rising male oropharyngeal cancer rates, and lack of HPV awareness.
[Letter].
Lancet Infectious Diseases
, 19
(2)
pp. 131-132.
10.1016/S1473-3099(18)30802-8.
|
|
Lechner, M;
Liu, J;
Lund, VJ;
(2020)
Novel Biomarkers in Sinonasal Cancers: from Bench to Bedside.
Current Oncology Reports
, 22
(10)
10.1007/s11912-020-00947-2.
|
|
|
Lechner, M;
Schartinger, VH;
Steele, CD;
Nei, WL;
Ooft, ML;
Schreiber, L-M;
Pipinikas, CP;
... Lund, VJ; + view all
(2021)
Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy.
Nature Communications
, 12
(1)
, Article 117. 10.1038/s41467-020-20308-8.
|
|
|
Lechner, M;
Sutton, L;
Murkin, C;
Masterson, L;
O'Flynn, P;
Wareing, MJ;
Tatla, T;
(2020)
Squamous cell cancer of the temporal bone: a review of the literature.
European Archives of Oto-Rhino-Laryngology
10.1007/s00405-020-06281-4.
|
|
|
Lechner, M;
Vassie, C;
Kavasogullari, C;
Jones, O;
Howard, J;
Masterson, L;
Fenton, T;
... Gilson, R; + view all
(2018)
A cross-sectional survey of awareness of human papillomavirus-associated oropharyngeal cancers among general practitioners in the UK.
BMJ Open
, 8
(7)
, Article e023339. 10.1136/bmjopen-2018-023339.
|
|
|
Ledermann, JA;
Matias-Guiu, X;
Amant, F;
Concin, N;
Davidson, B;
Fotopoulou, C;
González-Martin, A;
... Fagotti, A; + view all
(2024)
ESGO–ESMO–ESP consensus conference recommendations on ovarian cancer: pathology and molecular biology and early, advanced and recurrent disease.
Annals of Oncology
, 35
(3)
pp. 248-266.
10.1016/j.annonc.2023.11.015.
|
|
Ledermann, JA;
Shapira-Frommer, R;
Santin, AD;
Lisyanskaya, AS;
Pignata, S;
Vergote, I;
Raspagliesi, F;
... Matulonis, UA; + view all
(2023)
Molecular determinants of clinical outcomes of pembrolizumab in recurrent ovarian cancer: Exploratory analysis of KEYNOTE-100.
Gynecologic Oncology
, 178
pp. 119-129.
10.1016/j.ygyno.2023.09.012.
|
|
Ledermann, JA;
Drew, Y;
Kristeleit, RS;
(2016)
Homologous recombination deficiency and ovarian cancer.
European Journal of Cancer
, 60
pp. 49-58.
10.1016/j.ejca.2016.03.005.
|
|
Lee, DDH;
Cardinale, D;
Saman, Y;
Hirst, RA;
Wilson, N;
Corden, V;
Rutman, A;
... O'Callaghan, C; + view all
(2022)
COVID-19: Extensive epithelial damage and ciliary dyskinesia in hospitalised patients.
Rhinology
10.4193/Rhin21.233.
(In press).
|
|
Lee, Lennard YW;
Ionescu, Maria C;
Starkey, Thomas;
Little, Martin;
Tilby, Michael;
Tripathy, Arvind R;
Mckenzie, Hayley S;
... Johnson, Prof Peter; + view all
(2022)
COVID-19: Third dose booster vaccine effectiveness against breakthrough coronavirus infection, hospitalisations and death in patients with cancer: A population-based study.
European Journal of Cancer
10.1016/j.ejca.2022.06.038.
(In press).
|
|
|
Lee, Lennard YW;
Starkey, Thomas;
Ionescu, Maria C;
Little, Martin;
Tilby, Michael;
Tripathy, Arvind R;
Mckenzie, Hayley S;
... Robinson, Kate; + view all
(2022)
Vaccine effectiveness against COVID-19 breakthrough infections in patients with cancer (UKCCEP): a population-based test-negative case-control study.
The Lancet Oncology
, 23
(6)
pp. 748-757.
10.1016/s1470-2045(22)00202-9.
|
|
Lee, Lennard YW;
Tilby, Michael;
Starkey, Thomas;
Ionescu, Maria C;
Burnett, Alex;
Hattersley, Rosie;
Khan, Sam;
... Johnson, Peter; + view all
(2023)
Association of SARS-CoV-2 Spike Protein Antibody Vaccine Response With Infection Severity in Patients With Cancer:
A National COVID Cancer Cross-sectional Evaluation.
JAMA Oncology
, 9
(2)
pp. 188-196.
10.1001/jamaoncol.2022.5974.
|
|
Lee, A;
(2020)
Clinical Portrait of the SARS-CoV-2 Epidemic in European Patients with Cancer.
Cancer Discovery
, 10
(10)
pp. 1465-1474.
10.1158/2159-8290.CD-20-0773.
|
|
Lee, A;
Waterhouse, J;
Linch, M;
(2020)
Changing Paradigms in the Treatment of Advanced Urothelial Carcinoma: A 2020 Update.
EMJ Oncology
, 8
(3)
10.33590/emj/20-00044.
|
|
|
Lee, AJX;
Benamore, R;
Hofer, M;
Chitnis, M;
(2016)
Leptomeningeal carcinomatosis in non-small-cell lung cancer: initial response to erlotinib followed by relapse despite continuing radiological resolution of disease.
Oxford Medical Case Reports
, 2016
(9)
, Article omw069. 10.1093/omcr/omw069.
|
|
|
Lee, AJX;
Michail, M;
Quaderi, SA;
Richardson, JA;
Aggarwal, SK;
Speechly-Dick, ME;
(2015)
Implementation of NICE Clinical Guideline 95 for assessment of stable chest pain in a rapid access chest pain clinic reduces the mean number of investigations and cost per patient.
Open Heart
, 2
(1)
, Article e000151. 10.1136/openhrt-2014-000151.
|
|
|
Lee, AJX;
Purshouse, K;
(2021)
COVID-19 and cancer registries: learning from the first peak of the SARS-CoV-2 pandemic.
British Journal of Cancer
10.1038/s41416-021-01324-x.
(In press).
|
|
|
Lee, DDH;
Cardinale, D;
Nigro, E;
Butler, CR;
Rutman, A;
Fassad, MR;
Hirst, RA;
... O'Callaghan, C; + view all
(2021)
Higher throughput drug screening for rare respiratory diseases: Readthrough therapy in primary ciliary dyskinesia.
European Respiratory Journal
10.1183/13993003.00455-2020.
(In press).
|
|
|
Lee, DDH;
Petris, A;
Hynds, RE;
O'Callaghan, C;
(2019)
Ciliated Epithelial Cell Differentiation at Air-Liquid Interface Using Commercially Available Culture Media.
Methods in Molecular Biology
, 2109
pp. 275-291.
10.1007/7651_2019_269.
|
|
Lee, LYW;
Cazier, J-B;
Starkey, T;
Briggs, SEW;
Arnold, R;
Bisht, V;
Booth, S;
... UK Coronavirus Cancer Monitoring Project Team; + view all
(2020)
COVID-19 prevalence and mortality in patients with cancer and the effect of primary tumour subtype and patient demographics: a prospective cohort study.
The Lancet Oncology
, 21
(10)
pp. 1309-1316.
10.1016/S1470-2045(20)30442-3.
|
|
Lee, LYW;
Cazier, JB;
Starkey, T;
Turnbull, CD;
Kerr, R;
Middleton, G;
(2020)
COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study.
The Lancet
, 395
(10241)
pp. 1919-1926.
10.1016/S0140-6736(20)31173-9.
|
|
Lee, SM;
Falzon, M;
Blackhall, F;
Spicer, J;
Nicolson, M;
Chaudhuri, A;
Middleton, G;
... Hackshaw, A; + view all
(2016)
Randomized Prospective Biomarker Trial of ERCC1 for Comparing Platinum and Nonplatinum Therapy in Advanced Non-Small-Cell Lung Cancer: ERCC1 Trial (ET).
Journal of Clinical Oncology
, 35
(4)
pp. 402-411.
10.1200/JCO.2016.68.1841.
|
|
|
Lee, SM;
Hackshaw, A;
(2013)
A potential new enriching trial design for selecting non-small-cell lung cancer patients with no predictive biomarker for trials based on both histology and early tumor response: further analysis of a thalidomide trial.
Cancer Medicine
, 2
(3)
360 -366.
10.1002/cam4.74.
|
|
|
Lee, SM;
Upadhyay, S;
Lewanski, C;
Falk, S;
Skailes, G;
Woll, PJ;
Hatton, M;
... Hackshaw, A; + view all
(2019)
The clinical role of VeriStrat testing in patients with advanced non-small cell lung cancer considered unfit for first-line platinum-based chemotherapy.
European Journal of Cancer
, 120
pp. 86-96.
10.1016/j.ejca.2019.07.025.
|
|
|
Lee, W-C;
Reuben, A;
Hu, X;
McGranahan, N;
Chen, R;
Jalali, A;
Negrao, MV;
... Zhang, J; + view all
(2020)
Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity.
Genome Biology
, 21
(1)
, Article 271. 10.1186/s13059-020-02175-0.
|
|
|
Lemech, CR;
Ensell, L;
Paterson, JC;
Eminowicz, G;
Lowe, H;
Arora, R;
Arkenau, H-T;
... Kristeleit, RS; + view all
(2016)
Enumeration and Molecular Characterisation of Circulating Tumour Cells in Endometrial Cancer.
Oncology
, 91
(1)
pp. 48-54.
10.1159/000445999.
|
|
Leon, TE;
Rapoz-D'Silva, T;
Bertoli, C;
Rahman, S;
Magnussen, M;
Philip, B;
Farah, N;
... Mansour, MR; + view all
(2020)
EZH2 deficient T-cell acute lymphoblastic leukemia is sensitized to CHK1 inhibition through enhanced replication stress.
Cancer Discovery
, 10
(7)
10.1158/2159-8290.CD-19-0789.
|
|
Leone, G;
Passiglia, F;
Bironzo, P;
Bertaglia, V;
Novello, S;
(2020)
Is there any place for immune-checkpoint inhibitors in the treatment algorithm of fusion-driven non-small cell lung cancer? -a literature review.
Translational Lung Cancer Research
, 9
(6)
pp. 2674-2685.
10.21037/tlcr-20-710.
|
|
Leone, Gianmarco;
Orlando, Francesco;
Dutey-Magni, Peter;
Vainauskas, Osvaldas;
Grist, Emily;
Ciani, Yari;
Lall, Sharanpreet;
... the STAMPEDE collaborators; + view all
(2025)
Plasma AR Alterations and Timing of Intensified Hormone Treatment for Prostate Cancer:
the STAMPEDE Phase 3 Randomized Clinical Trial.
JAMA Oncology
10.1001/jamaoncol.2024.7051.
(In press).
|
|
|
Levin, Gabriel;
Harrison, Ross;
Ledermann, Jonathan;
Meyer, Raanan;
Coleman, Robert L;
Ramirez, Pedro T;
(2023)
Evaluating open access publication and research impact in gynecologic oncology.
International Journal of Gynecological Cancer
, 33
(7)
pp. 1112-1117.
10.1136/ijgc-2023-004460.
|
|
|
Levitt, JA;
Poland, SP;
Krstajic, N;
Pfisterer, K;
Erdogan, A;
Barber, PR;
Parsons, M;
... Ameer-Beg, SM; + view all
(2020)
Quantitative real-time imaging of intracellular FRET biosensor dynamics using rapid multi-beam confocal FLIM.
Scientific Reports
, 10
, Article 5146. 10.1038/s41598-020-61478-1.
|
|
|
Li, J;
Duran, MA;
Dhanota, N;
Chatila, WK;
Bettigole, SE;
Kwon, J;
Sriram, RK;
... Bakhoum, SF; + view all
(2021)
Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis.
Cancer Discovery
, 11
(5)
pp. 1212-1227.
10.1158/2159-8290.CD-20-0387.
|
|
Li, Y;
Jiang, G;
Wu, W;
Yang, H;
Jin, Y;
Wu, M;
Liu, W;
... Chen, K; + view all
(2023)
Multi-omics integrated circulating cell-free DNA genomic signatures enhanced the diagnostic performance of early-stage lung cancer and postoperative minimal residual disease.
eBioMedicine
, 91
, Article 104553. 10.1016/j.ebiom.2023.104553.
|
|
Li, BT;
Michelini, F;
Misale, S;
Cocco, E;
Baldino, L;
Cai, Y;
Shifman, S;
... Scaltriti, M; + view all
(2020)
HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers.
Cancer Discovery
, 10
(5)
pp. 674-687.
10.1158/2159-8290.cd-20-0215.
|
|
Liccardi, G.;
(2011)
Nuclear EGFR modulation of DNA repair.
Doctoral thesis , UCL (University College London).
|
|
|
Lidington, EK;
Smrke, A;
Ingley, KM;
Strauss, SJ;
Husson, O;
Younger, E;
(2020)
Cancer care and well-being in adolescents and young adults during the coronavirus disease 2019 pandemic: A UK sarcoma perspective.
Cancer
, 126
(24)
pp. 5359-5360.
10.1002/cncr.33215.
|
|
Liebert, Casril;
Morka, Naomi;
Satish, Pranav;
Freeman, Alex;
Kelly, Daniel;
Kirkham, Alex;
Orczyk, Clement;
... Norris, Joseph M; + view all
(2023)
Diagnostic potential of radiological apical tumor involvement.
Journal of Robotic Surgery
, 17
pp. 705-706.
10.1007/s11701-022-01413-w.
|
|
Lieverse, RIY;
Van Limbergen, EJ;
Oberije, CJG;
Troost, EGC;
Hadrup, SR;
Dingemans, A-MC;
Hendriks, LEL;
... Lambin, P; + view all
(2020)
Stereotactic ablative body radiotherapy (SABR) combined with immunotherapy (L19-IL2) versus standard of care in stage IV NSCLC patients, ImmunoSABR: a multicentre, randomised controlled open-label phase II trial.
BMC Cancer
, 20
, Article 557. 10.1186/s12885-020-07055-1.
|
|
|
Lin, Lin;
Lin, Guangyao;
Zhou, Qingtong;
Bathgate, Ross AD;
Gong, Grace Qun;
Yang, Dehua;
Liu, Qing;
(2021)
Design, synthesis and pharmacological evaluation of tricyclic derivatives as selective RXFP4 agonists.
Bioorganic Chemistry
, 110
, Article 104782. 10.1016/j.bioorg.2021.104782.
|
|
Lin, CC;
Arkenau, HT;
Lu, S;
Sachdev, J;
de Castro Carpeño, J;
Mita, M;
Dziadziuszko, R;
... Weiss, GJ; + view all
(2019)
A phase 1, open-label, dose-escalation trial of oral TSR-011 in patients with advanced solid tumours and lymphomas.
British Journal of Cancer
, 121
pp. 131-138.
10.1038/s41416-019-0503-9.
|
|
|
Linch, M;
Lee, A;
(2020)
Positioning checkpoint blockade in urothelial cancer: PURE-01 and PEANUTS.
Annals of Oncology
, 31
(12)
pp. 1601-1602.
10.1016/j.annonc.2020.10.468.
|
|
Linch, M;
Attard, G;
(2018)
Prostate cancers that `Wnt' respond to abiraterone.
Annals of Oncology
, 29
(2)
pp. 290-292.
10.1093/annonc/mdx785.
|
|
Linch, M;
Goh, G;
Hiley, C;
Shanmugabavan, Y;
McGranahan, N;
Rowan, A;
Wong, YNS;
... Swanton, C; + view all
(2017)
Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters.
Annals of Oncology
, 28
(10)
pp. 2472-2480.
10.1093/annonc/mdx355.
|
|
Lindsay, CR;
Shaw, EC;
Moore, DA;
Rassl, D;
Jamal-Hanjani, M;
Steele, N;
Naheed, S;
... Kerr, KM; + view all
(2021)
Large cell neuroendocrine lung carcinoma: consensus statement from The British Thoracic Oncology Group and the Association of Pulmonary Pathologists.
British Journal of Cancer
10.1038/s41416-021-01407-9.
(In press).
|
|
|
Lindsay, CR;
Jamal-Hanjani, M;
Forster, M;
Blackhall, F;
(2018)
KRAS: Reasons for optimism in lung cancer.
European Journal of Cancer
, 99
pp. 20-27.
10.1016/j.ejca.2018.05.001.
|
|
Lipton, L.R.;
(2006)
Familial colorectal cancer and polyposis genes, pathways and predictions.
Doctoral thesis , University of London.
|
|
|
Lise, S;
Archambeau, C;
Pontil, M;
Jones, DT;
(2009)
Prediction of hot spot residues at protein-protein interfaces by combining machine learning and energy-based methods.
BMC Bioinformatics
, 10
, Article 365. 10.1186/1471-2105-10-365.
|
|
|
Litchfield, K;
Levy, M;
Orlando, G;
Loveday, C;
Law, PJ;
Migliorini, G;
Holroyd, A;
... Turnbull, C; + view all
(2017)
Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor.
Nature Genetics
, 49
(7)
pp. 1133-1140.
10.1038/ng.3896.
|
|
Litchfield, K;
Reading, JL;
Lim, EL;
Xu, H;
Liu, P;
Al-Bakir, M;
Wong, YNS;
... Swanton, C; + view all
(2020)
Escape from nonsense-mediated decay associates with anti-tumor immunogenicity.
Nature Communications
, 11
, Article 3800. 10.1038/s41467-020-17526-5.
|
|
|
Litchfield, K;
Reading, JL;
Puttick, C;
Thakkar, K;
Abbosh, C;
Bentham, R;
Watkins, TBK;
... Swanton, C; + view all
(2021)
Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition.
Cell
, 184
(3)
596-614.e14.
10.1016/j.cell.2021.01.002.
|
|
|
Litchfield, K;
Stanislaw, S;
Spain, L;
Gallegos, LL;
Rowan, A;
Schnidrig, D;
Rosenbaum, H;
... Turajlic, S; + view all
(2020)
Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue.
Cell Reports
, 31
(5)
p. 107550.
10.1016/j.celrep.2020.107550.
|
|
Litchfield, K;
Turajlic, S;
Swanton, C;
(2017)
The GENIE Is Out of the Bottle: Landmark Cancer Genomics Dataset Released.
Cancer Discovery
, 7
(8)
pp. 796-798.
10.1158/2159-8290.CD-17-0604.
|
|
|
Liu, MC;
Oxnard, GR;
Klein, EA;
Swanton, C;
Seiden, MV;
CCGA Consortium, .;
(2020)
Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA.
Annals of Oncology
, 31
(6)
pp. 745-759.
10.1016/j.annonc.2020.02.011.
|
|
Liu, B;
Pett, L;
Kiakos, K;
Patil, PC;
Satam, V;
Hartley, JA;
Lee, M;
(2018)
DNA-binding properties of new fluorescent AzaHx-amides: Methoxy-pyridyl-aza-benzimidazole-pyrrole-imidazole/pyrrole.
ChemBioChem
, 19
(18)
pp. 1979-1987.
10.1002/cbic.201800273.
|
|
Livanos, Maria;
(2019)
Production of DARPins in the Yeast Pichia pastoris.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Llimos, Gerard;
Gardeux, Vincent;
Koch, Ute;
Kribelbauer, Judith F;
Hafner, Antonina;
Alpern, Daniel;
Pezoldt, Joern;
... Deplancke, Bart; + view all
(2022)
A leukemia-protective germline variant mediates chromatin module formation via transcription factor nucleation.
Nature Communications
, 13
(1)
, Article 2042. 10.1038/s41467-022-29625-6.
|
|
Llovet, JM;
Kudo, M;
Merle, P;
Meyer, T;
Qin, S;
Ikeda, M;
Xu, R;
... Finn, RS; + view all
(2023)
Lenvatinib plus pembrolizumab versus lenvatinib plus placebo for advanced hepatocellular carcinoma (LEAP-002): a randomised, double-blind, phase 3 trial.
The Lancet Oncology
, 24
(12)
pp. 1399-1410.
10.1016/S1470-2045(23)00469-2.
|
|
Llovet, JM;
Villanueva, A;
Marrero, JA;
Schwartz, M;
Meyer, T;
Galle, PR;
Lencioni, R;
... Roberts, LR; + view all
(2021)
Trial Design and Endpoints in Hepatocellular Carcinoma: AASLD Consensus Conference.
Hepatology
, 73
(S1)
pp. 158-191.
10.1002/hep.31327.
|
|
Loennstedt, Ingrid M;
Caramia, Franco;
Li, Jason;
Fumagalli, Debora;
Salgado, Roberto;
Rowan, Andrew;
Salm, Max;
... Speed, Terence P; + view all
(2014)
Deciphering clonality in aneuploid breast tumors using SNP array and sequencing data.
Genome Biology
, 15
(9)
, Article 470. 10.1186/s13059-014-0470-7.
|
|
|
Lopez, S;
(2014)
Identification of genes and biological pathways involved in human skin pigmentation variability in an evolutionary framework.
Doctoral thesis , UNSPECIFIED.
|
|
López, S;
Lim, EL;
Horswell, S;
Haase, K;
Huebner, A;
Dietzen, M;
Mourikis, TP;
... McGranahan, N; + view all
(2020)
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution.
Nature Genetics
, 52
(3)
pp. 283-293.
10.1038/s41588-020-0584-7.
|
|
Lopez-Garcia, C;
Sansregret, L;
Domingo, E;
McGranahan, N;
Hobor, S;
Birkbak, NJ;
Horswell, S;
... Swanton, C; + view all
(2017)
BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer.
Cancer Cell
, 31
(1)
pp. 79-93.
10.1016/j.ccell.2016.11.001.
|
|
Lopez-Guadamillas, E;
Fernandez-Marcos, PJ;
Pantoja, C;
Muñoz-Martin, M;
MartÃnez, D;
Gómez-López, G;
Campos-Olivas, R;
... Serrano, M; + view all
(2016)
p21(Cip1) plays a critical role in the physiological adaptation to fasting through activation of PPARα.
Sci Rep
, 6
, Article 34542. 10.1038/srep34542.
|
|
|
Lopez-Guadamillas, E;
Muñoz-Martin, M;
Martinez, S;
Pastor, J;
Fernandez-Marcos, PJ;
Serrano, M;
(2016)
PI3Kα inhibition reduces obesity in mice.
Aging
, 8
(11)
pp. 2747-2753.
10.18632/aging.101075.
|
|
|
Lorente, D;
Omlin, A;
Zafeiriou, Z;
Nava-Rodrigues, D;
Pérez-López, R;
Pezaro, C;
Mehra, N;
... de Bono, J; + view all
(2016)
Castration-Resistant Prostate Cancer Tissue Acquisition From Bone Metastases for Molecular Analyses.
Clinical Genitourinary Cancer
, 14
(6)
pp. 485-493.
10.1016/j.clgc.2016.04.016.
|
|
|
Loveday, C;
Law, P;
Litchfield, K;
Levy, M;
Holroyd, A;
Broderick, P;
Kote-Jarai, Z;
... Turnbull, C; + view all
(2018)
Large-scale Analysis Demonstrates Familial Testicular Cancer to have Polygenic Aetiology.
European Urology
, 74
(3)
pp. 248-252.
10.1016/j.eururo.2018.05.036.
|
|
|
Loveday, C;
Litchfield, K;
Levy, M;
Holroyd, A;
Broderick, P;
Kote-Jarai, Z;
Dunning, AM;
... Turnbull, C; + view all
(2018)
Validation of loci at 2q14.2 and 15q21.3 as risk factors for testicular cancer.
Oncotarget
, 9
(16)
pp. 12630-12638.
10.18632/oncotarget.23117.
|
|
Loveday, C;
Litchfield, K;
Proszek, PZ;
Cornish, AJ;
Santo, F;
Levy, M;
Macintyre, G;
... Turnbull, C; + view all
(2020)
Genomic landscape of platinum resistant and sensitive testicular cancers.
Nature Communications
, 11
, Article 2189. 10.1038/s41467-020-15768-x.
|
|
|
Loveday, C;
Sud, A;
Litchfield, K;
Levy, M;
Holroyd, A;
Broderick, P;
Kote-Jarai, Z;
... Turnbull, C; + view all
(2019)
Runs of homozygosity and testicular cancer risk.
Andrology
, 7
(4)
pp. 555-564.
10.1111/andr.12667.
|
|
Lowe, H.L.;
(2011)
Design, construction and evaluation of a humanised ADEPT system.
Doctoral thesis , UCL (University College London).
|
|
Lu, Wei-Ting;
Kanu, Nnennaya;
(2025)
FAT1 alterations contribute to chromosomal instability in cancer cells.
Nature Cell Biology
, 27
(1)
pp. 12-13.
10.1038/s41556-024-01559-9.
|
|
Lu, L;
Teixeira, VH;
Yuan, Z;
Graham, TA;
Endesfelder, D;
Kolluri, K;
Al-Juffali, N;
... Janes, SM; + view all
(2013)
LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development.
J Pathol
, 229
(4)
608 - 620.
10.1002/path.4148.
|
|
|
Lucas, Olivia;
Ward, Sophia;
Zaidi, Rija;
Bunkum, Abigail;
Frankell, Alexander M;
Moore, David A;
Hill, Mark S;
... Zaccaria, Simone; + view all
(2024)
Characterizing the evolutionary dynamics of cancer proliferation in single-cell clones with SPRINTER.
Nature Genetics
10.1038/s41588-024-01989-z.
(In press).
|
|
|
Luo, J;
Attard, G;
Balk, SP;
Bevan, C;
Burnstein, K;
Cato, L;
Cherkasov, A;
... Raj, GV; + view all
(2018)
Role of Androgen Receptor Variants in Prostate Cancer: Report from the 2017 Mission Androgen Receptor Variants Meeting.
European Urology
, 73
(5)
pp. 715-723.
10.1016/j.eururo.2017.11.038.
|
|
Luszczak, S;
Kumar, C;
Sathyadevan, VK;
Simpson, BS;
Gately, KA;
Whitaker, HC;
Heavey, S;
(2020)
PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer.
Signal Transduction and Targeted Therap
, 5
(1)
, Article 7. 10.1038/s41392-020-0109-y.
|
|
|
Luszczak, S;
Simpson, BS;
Stopka-Farooqui, U;
Sathyadevan, VK;
Echeverria, LMC;
Kumar, C;
Costa, H;
... Heavey, S; + view all
(2020)
Author Correction: Co-targeting PIM and PI3K/mTOR using multikinase inhibitor AUM302 and a combination of AZD-1208 and BEZ235 in prostate cancer.
[Corrigendum].
Scientific Reports
, 10
, Article 19870. 10.1038/s41598-020-76679-x.
|
|
|
Luszczak, S;
Simpson, BS;
Stopka-Farooqui, U;
Sathyadevan, VK;
Echeverria, LMC;
Kumar, C;
Costa, H;
... Heavey, S; + view all
(2020)
Co-targeting PIM and PI3K/mTOR using multikinase inhibitor AUM302 and a combination of AZD-1208 and BEZ235 in prostate cancer.
Scientific Reports
, 10
, Article 14380. 10.1038/s41598-020-71263-9.
|
|
|
Luxton, HJ;
Simpson, BS;
Mills, IG;
Brindle, NR;
Ahmed, Z;
Stavrinides, V;
Heavey, S;
... Whitaker, HC; + view all
(2019)
The Oncogene Metadherin Interacts with the Known Splicing Proteins YTHDC1, Sam68 and T-STAR and Plays a Novel Role in Alternative mRNA Splicing.
Cancers
, 11
(9)
, Article 1233. 10.3390/cancers11091233.
|
|
M
|
M, Ahmed;
S, Collins;
J, Franks;
C, Lobo;
A, Bacon;
L, Paley;
SJ, Strauss;
(2022)
Incidence and Outcome of Breast Sarcomas in England (2013–2018): An analysis from the National Cancer Registration and Analysis Service.
European Journal of Cancer
, 174
pp. 48-56.
10.1016/j.ejca.2022.06.036.
|
|
Mackay, HL;
Moore, D;
Hall, C;
Birkbak, NJ;
Jamal-Hanjani, M;
Karim, SA;
Phatak, VM;
... Muller, PAJ; + view all
(2018)
Genomic instability in mutant p53 cancer cells upon entotic engulfment.
Nature Communications
, 9
, Article 3070. 10.1038/s41467-018-05368-1.
|
|
|
Madsen, Ralitsa R;
Le Marois, Alix;
Mruk, Oliwia N;
Voliotis, Margaritis;
Yin, Shaozhen;
Sufi, Jahangir;
Qin, Xiao;
... Vanhaesebroeck, Bart; + view all
(2024)
Oncogenic PIK3CA corrupts growth factor signaling specificity.
Molecular Systems Biology
10.1038/s44320-024-00078-x.
(In press).
|
|
|
Madsen, RR;
Erickson, EC;
Rueda, OM;
Robin, X;
Caldas, C;
Toker, A;
Semple, RK;
(2021)
Positive correlation between transcriptomic stemness and PI3K/AKT/mTOR signaling scores in breast cancer, and a counterintuitive relationship with PIK3CA genotype.
PLOS Genetics
, 17
(11)
, Article e1009876. 10.1371/journal.pgen.1009876.
|
|
|
Madsen, RR;
(2020)
PI3K in stemness regulation: from development to cancer.
Biochemical Society Transactions
, 2020
, Article BST20190778. 10.1042/BST20190778.
|
|
|
Madsen, RR;
Knox, RG;
Pearce, W;
Lopez, S;
Mahler-Araujo, B;
McGranahan, N;
Vanhaesebroeck, B;
(2019)
Oncogenic PIK3CA promotes cellular stemness in an allele dose-dependent manner.
Proceedings of the National Academy of Sciences of The United States of America
10.1073/pnas.1821093116.
(In press).
|
|
|
Madsen, RR;
Longden, J;
Knox, RG;
Robin, X;
Völlmy, F;
Macleod, KG;
Moniz, LS;
... Semple, RK; + view all
(2021)
NODAL/TGFβ signalling mediates the self-sustained stemness induced by PIK3CAH1047R homozygosity in pluripotent stem cells.
Disease Models & Mechanisms
10.1242/dmm.048298.
(In press).
|
|
|
Madsen, RR;
Vanhaesebroeck, B;
(2020)
Cracking the context-specific PI3K signaling code.
Science Signaling
, 13
(613)
, Article eaay2940. 10.1126/scisignal.aay2940.
|
|
|
Madsen, RR;
Vanhaesebroeck, B;
Semple, RK;
(2018)
Cancer-Associated PIK3CA Mutations in Overgrowth Disorders.
Trends in Molecular Medicine
, 24
(10)
10.1016/j.molmed.2018.08.003.
|
|
|
Maffucci, T;
Raimondi, C;
Abu-Hayyeh, S;
Dominguez, V;
Sala, G;
Zachary, I;
Falasca, M;
(2009)
A Phosphoinositide 3-Kinase/Phospholipase Cgamma1 Pathway Regulates Fibroblast Growth Factor-Induced Capillary Tube Formation.
PLOS ONE
, 4
(12)
, Article e8285. 10.1371/journal.pone.0008285.
|
|
|
Maggio, V;
Canovas, V;
Felix, AJ;
Gomez, V;
de Torres, I;
Eugenia Semidey, M;
Morote, J;
... Paciucci, R; + view all
(2019)
A novel DNA-binding motif in prostate tumor overexpressed-1 (PTOV1) required for the expression of ALDH1A1 and CCNG2 in cancer cells.
Cancer Letters
, 452
pp. 158-167.
10.1016/j.canlet.2019.03.019.
|
|
|
Maher, GJ;
Ralph, HK;
Ding, Z;
Koelling, N;
Mlcochova, H;
Giannoulatou, E;
Dhami, P;
... Goriely, A; + view all
(2018)
Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testes.
Genome Research
, 28
(12)
pp. 1779-1790.
10.1101/gr.239186.118.
|
|
|
Mahmood, Umair;
Muhamad Faizul, Elisya;
Howlett, Sarah;
Amin, Zahir;
Hochhauser, Daniel;
Shiu, Kai-Keen;
Bridgewater, John;
(2024)
Comprehensive Examination of Cholangiocarcinoma Patients Treated with Novel Targeted Therapies after Extended Molecular Profiling on Liquid Biopsies.
Cancers
, 16
(4)
, Article 697. 10.3390/cancers16040697.
|
|
Mahmud-Al-Rafat, A;
Majumder, A;
Rahman, KMT;
Hasan, AMM;
Islam, KMD;
Taylor-Robinson, AW;
Billah, MM;
(2019)
Decoding the enigma of antiviral crisis: Does one target molecule regulate all?
Cytokine
, 115
pp. 13-23.
10.1016/j.cyto.2018.12.008.
|
|
|
Maiani, E;
Milletti, G;
Nazio, F;
Holdgaard, SG;
Bartkova, J;
Rizza, S;
Cianfanelli, V;
... Cecconi, F; + view all
(2021)
AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity.
Nature
, 592
(7856)
pp. 799-803.
10.1038/s41586-021-03422-5.
|
|
Main, KHS;
Provan, JI;
Haynes, PJ;
Wells, G;
Hartley, JA;
Pyne, ALB;
(2021)
Atomic force microscopy—A tool for structural and translational DNA research.
APL Bioengineering
, 5
(3)
, Article 031504. 10.1063/5.0054294.
(In press).
|
|
|
Mak, G;
Moschetta, M;
Arkenau, H-T;
(2016)
Reporting incidental germline variants in the context of day-to-day somatic genomic profiling.
Annals of Oncology
, 27
(5)
pp. 758-759.
10.1093/annonc/mdw078.
|
|
Mak, G;
Soria, J-C;
Blagden, SP;
Plummer, R;
Fleming, RA;
Nebot, N;
Zhang, J;
... Arkenau, H-T; + view all
(2019)
A phase Ib dose-finding, pharmacokinetic study of the focal adhesion kinase inhibitor GSK2256098 and trametinib in patients with advanced solid tumours.
British Journal of Cancer
(120)
pp. 975-981.
10.1038/s41416-019-0452-3.
|
|
|
Malcolm, JC;
Falzone, N;
Gains, JE;
Aldridge, MD;
Mirando, D;
Lee, BQ;
Gaze, MN;
(2022)
Impact of cyclic changes in pharmacokinetics and absorbed dose in pediatric neuroblastoma patients receiving [177Lu]Lu-DOTATATE.
EJNMMI Physics
, 9
, Article 24. 10.1186/s40658-022-00436-4.
|
|
Maley, CC;
Aktipis, A;
Graham, TA;
Sottoriva, A;
Boddy, AM;
Janiszewska, M;
Silva, AS;
... Shibata, D; + view all
(2017)
Classifying the evolutionary and ecological features of neoplasms.
Nature Reviews Cancer
, 17
(10)
pp. 605-619.
10.1038/nrc.2017.69.
|
|
|
Mandair, D;
Khan, MS;
Lopes, A;
Furtado O'Mahony, L;
Ensell, L;
Lowe, H;
Hartley, JA;
... Meyer, T; + view all
(2021)
Prognostic Threshold for Circulating Tumor Cells in Patients With Pancreatic and Midgut Neuroendocrine Tumors.
Journal of Clinical Endocrinology and Metabolism
, 106
(3)
pp. 872-882.
10.1210/clinem/dgaa822.
|
|
Mandair, D;
Vesely, C;
Ensell, L;
Lowe, H;
Spanswick, V;
Hartley, JA;
Caplin, ME;
(2016)
A comparison of CellCollector with CellSearch in patients with neuroendocrine tumours.
Endocrine-Related Cancer
, 23
(10)
L29-L32.
10.1530/ERC-16-0201.
|
|
Mansoor, W;
Arkenau, H-T;
Alsina, M;
Shitara, K;
Thuss-Patience, P;
Cuffe, S;
Dvorkin, M;
... Van Cutsem, E; + view all
(2021)
Trifluridine/tipiracil in patients with metastatic gastroesophageal junction cancer: a subgroup analysis from the phase 3 TAGS study.
Gastric Cancer
10.1007/s10120-021-01156-x.
(In press).
|
|
|
Marabelle, A;
Baurain, J-F;
Awada, A;
Kristeleit, RS;
Jossang, D-E;
Jebsen, N-L;
Loirat, D;
... Spicer, J; + view all
(2017)
LTX‐315, an oncolytic peptide converts "cold" tumors to "hot" in a majority of patients with advanced cancer: results from an ongoing phase I study.
Presented at: 32nd Annual Meeting and Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2017): Part Two, National Harbor, Maryland, USA.
|
|
|
Marchetti, C;
Kristeleit, R;
McCormack, M;
Mould, T;
Olaitan, A;
Widschwendter, M;
MacDonald, N;
(2017)
Outcome of patients with advanced ovarian cancer who do not undergo debulking surgery: A single institution retrospective review.
Gynecologic Oncology
, 144
(1)
pp. 57-60.
10.1016/j.ygyno.2016.11.001.
|
|
Marculescu, C;
Kossen, H;
Morgan, RE;
Mayer, P;
Fletcher, SA;
Tolner, B;
Chester, KA;
... Baker, JR; + view all
(2014)
Aryloxymaleimides for cysteine modification, disulfide bridging and the dual functionalization of disulfide bonds.
Chemical Communications
, 50
(54)
pp. 7139-7142.
10.1039/c4cc02107j.
|
|
|
Mardakheh, FK;
Sailem, HZ;
Kümper, S;
Tape, CJ;
McCully, RR;
Paul, A;
Anjomani-Virmouni, S;
... Bakal, C; + view all
(2017)
Proteomics profiling of interactome dynamics by colocalisation analysis (COLA).
Molecular BioSystems
, 13
(1)
pp. 92-105.
10.1039/c6mb00701e.
|
|
|
Marina, NM;
Smeland, S;
Bielack, SS;
Bernstein, M;
Jovic, G;
Krailo, MD;
Hook, JM;
... Whelan, JS; + view all
(2016)
Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial.
The Lancet Oncology
, 17
(10)
pp. 1396-1408.
10.1016/S1470-2045(16)30214-5.
|
|
|
Marklund, Maja;
Schultz, Niklas;
Friedrich, Stefanie;
Berglund, Emelie;
Tarish, Firas;
Tanoglidi, Anna;
Liu, Yao;
... Lundeberg, Joakim; + view all
(2022)
Spatio-temporal analysis of prostate tumors in situ suggests pre-existence of treatment-resistant clones.
Nature Communications
, 13
, Article 5475. 10.1038/s41467-022-33069-3.
|
|
Marth, C;
Vergote, I;
Scambia, G;
Oberaigner, W;
Clamp, A;
Berger, R;
Kurzeder, C;
... Bach, BA; + view all
(2017)
ENGOT-ov-6/TRINOVA-2: Randomised, double-blind, phase 3 study of pegylated liposomal doxorubicin plus trebananib or placebo in women with recurrent partially platinum-sensitive or resistant ovarian cancer.
European Journal of Cancer
, 70
pp. 111-121.
10.1016/j.ejca.2016.09.004.
|
|
Martin, L-A;
Ribas, R;
Simigdala, N;
Schuster, E;
Pancholi, S;
Tenev, T;
Gellert, P;
... Dowsett, M; + view all
(2017)
Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance.
Nature Communications
, 8
, Article 1865. 10.1038/s41467-017-01864-y.
|
|
|
Martinez, V;
Pankova, V;
Krasney, L;
Singh, T;
White, I;
Benjamin, A;
dertsching, S;
... Acton, S; + view all
(2019)
Conduit integrity is compromised during acute lymph node expansion.
BioRxiv: Cold Spring Harbor, NY, USA.
|
|
Martinez, VG;
Pankova, V;
Krasny, L;
Singh, T;
Makris, S;
White, IJ;
Benjamin, AC;
... Acton, SE; + view all
(2019)
Fibroblastic Reticular Cells Control Conduit Matrix Deposition during Lymph Node Expansion.
Cell Reports
, 29
(9)
2810-2822.e5.
10.1016/j.celrep.2019.10.103.
|
|
|
Martínez-Mármol, R;
Mohannak, N;
Qian, L;
Wang, T;
Gormal, RS;
Ruitenberg, MJ;
Vanhaesebroeck, B;
... Meunier, FA; + view all
(2019)
p110δ PI 3-kinase inhibition perturbs APP and TNFα trafficking, reduces plaque burden, dampens neuroinflammation and prevents cognitive decline in an Alzheimer's disease mouse model.
The Journal of Neuroscience
, 39
(40)
pp. 7976-7991.
10.1523/JNEUROSCI.0674-19.2019.
|
|
Martínez-Ruiz, C;
Black, JRM;
Puttick, C;
Hill, MS;
Demeulemeester, J;
Larose Cadieux, E;
Thol, K;
... McGranahan, N; + view all
(2023)
Genomic–transcriptomic evolution in lung cancer and metastasis.
Nature
, 616
pp. 543-552.
10.1038/s41586-023-05706-4.
|
|
Martins, Filipe Correia;
Couturier, Dominique-Laurent;
De Santiago, Ines;
Sauer, Carolin Margarethe;
Vias, Maria;
Angelova, Mihaela;
Sanders, Deborah;
... Brenton, James D; + view all
(2022)
Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer.
Nature Communications
, 13
(1)
, Article 6360. 10.1038/s41467-022-33870-0.
|
|
Maruani, A;
Smith, ME;
Miranda, E;
Chester, KA;
Chudasama, V;
Caddick, S;
(2015)
A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy.
Nat Commun
, 6
, Article 6645. 10.1038/ncomms7645.
|
|
|
Marzec, J;
Ross-Adams, H;
Pirrò, S;
Wang, J;
Zhu, Y;
Mao, X;
Gadaleta, E;
... Chelala, C; + view all
(2021)
The Transcriptomic Landscape of Prostate Cancer Development and Progression: An Integrative Analysis.
Cancers
, 13
(2)
, Article 345. 10.3390/cancers13020345.
|
|
|
Mason, MD;
Clarke, NW;
James, ND;
Dearnaley, DP;
Spears, MR;
Ritchie, AWS;
Attard, G;
... STAMPEDE Investigators, .; + view all
(2017)
Adding Celecoxib With or Without Zoledronic Acid for Hormone-Naïve Prostate Cancer: Long-Term Survival Results From an Adaptive, Multiarm, Multistage, Platform, Randomized Controlled Trial.
Journal of Clincal Oncology
, 35
(14)
pp. 1530-1541.
10.1200/JCO.2016.69.0677.
|
|
|
Masoud, AG;
Lin, J;
Zhu, LF;
Tao, K;
Ness, NW;
Kassiri, Z;
Moore, RB;
... Murray, AG; + view all
(2023)
Endothelial phosphoinositide 3-kinase-β inactivation confers protection from immune-mediated vascular injury.
American Journal of Transplantation
, 23
(2)
pp. 202-213.
10.1016/j.ajt.2022.11.014.
|
|
Massana-Muñoz, Xènia;
Goret, Marie;
Nattarayan, Vasugi;
Reiss, David;
Kretz, Christine;
Chicanne, Gaetan;
Payrastre, Bernard;
... Laporte, Jocelyn; + view all
(2023)
Inactivating the lipid kinase activity of PI3KC2β is sufficient to rescue myotubular myopathy in mice.
JCI Insight
, 8
(9)
, Article e151933. 10.1172/jci.insight.151933.
|
|
|
Massard, C;
Mateo, J;
Loriot, Y;
Pezaro, C;
Albiges, L;
Mehra, N;
Varga, A;
... de Bono, J; + view all
(2017)
Phase I/II trial of cabazitaxel plus abiraterone in patients with metastatic castration-resistant prostate cancer (mCRPC) progressing after docetaxel and abiraterone.
Annals of Oncology
, 28
(1)
pp. 90-95.
10.1093/annonc/mdw441.
|
|
|
Mateo, J;
Chakravarty, D;
Dienstmann, R;
Jezdic, S;
Gonzalez-Perez, A;
Lopez-Bigas, N;
Ng, CKY;
... Pusztai, L; + view all
(2018)
A framework to rank genomic alterations as targets for cancer precision medicine: the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT).
Annals of Oncology
, 29
(9)
pp. 1895-1902.
10.1093/annonc/mdy263.
|
|
|
Mateo, J;
Ganji, G;
Lemech, C;
Burris, HA;
Han, S-W;
Swales, K;
Decordova, S;
... Arkenau, H-T; + view all
(2017)
A First-Time-in-Human Study of GSK2636771, a Phosphoinositide 3 Kinase Beta-Selective Inhibitor, in Patients with Advanced Solid Tumors.
Clinical Cancer Research
, 23
(19)
pp. 5981-5992.
10.1158/1078-0432.CCR-17-0725.
|
|
|
Matharu, RK;
Tabish, TA;
Trakoolwilaiwan, T;
Mansfield, J;
Moger, J;
Wu, T;
Lourenço, C;
... Edirisinghe, M; + view all
(2020)
Microstructure and antibacterial efficacy of graphene oxide nanocomposite fibres.
Journal of Colloid and Interface Science
, 571
pp. 239-252.
10.1016/j.jcis.2020.03.037.
|
|
Mathew, NR;
Baumgartner, F;
Braun, L;
O'Sullivan, D;
Thomas, S;
Waterhouse, M;
Mueller, TA;
... Zeiser, R; + view all
(2018)
Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.
Nature Medicine
, 24
(3)
pp. 282-291.
10.1038/nm.4484.
|
|
MATTES, WB;
HARTLEY, JA;
KOHN, KW;
(1986)
Dna-sequence selectivity of guanine-n7 alkylation by nitrogen mustards.
Nucleic Acids Research
, 14
(7)
2971 - 2987.
10.1093/nar/14.7.2971.
|
|
|
Matulonis, Ursula A;
Herrstedt, Jorn;
Oza, Amit;
Mahner, Sven;
Redondo, Andres;
Berton, Dominique;
Berek, Jonathan S;
... Mirza, Mansoor R; + view all
(2025)
ENGOT-OV16/NOVA trial of niraparib in recurrent ovarian cancer: Survival and long-term safety.
Gynecologic Oncology
, 195
pp. 192-199.
10.1016/j.ygyno.2025.03.018.
|
|
Maughan, Elizabeth F;
Hynds, Robert E;
Pennycuick, Adam;
Nigro, Ersilia;
Gowers, Kate HC;
Denais, Celine;
Gómez-López, Sandra;
... Janes, Sam M; + view all
(2022)
Cell-intrinsic differences between human airway epithelial cells from children and adults.
iScience
, 25
(11)
, Article 105409. 10.1016/j.isci.2022.105409.
|
|
Maughan, E;
Lesage, F;
Butler, CR;
Hynds, RE;
Hewitt, R;
Janes, SM;
Deprest, JA;
(2016)
Airway tissue engineering for congenital laryngotracheal disease.
Seminars in Pediatric Surgery
, 25
(3)
pp. 186-190.
10.1053/j.sempedsurg.2016.02.012.
|
|
Maughan, EF;
Butler, CR;
Crowley, C;
Teoh, GZ;
Hondt, MD;
Hamilton, NJ;
Hynds, RE;
... Elliott, MJ; + view all
(2017)
A comparison of tracheal scaffold strategies for pediatric transplantation in a rabbit model.
The Laryngoscope
, 127
(12)
E449-E457.
10.1002/lary.26611.
|
|
Maughan, EF;
Hynds, RE;
Proctor, TJ;
Janes, SM;
Elliott, M;
Birchall, MA;
Lowdell, MW;
(2017)
Autologous Cell Seeding in Tracheal Tissue Engineering.
Current Stem Cell Reports
, 3
(4)
pp. 279-289.
10.1007/s40778-017-0108-2.
|
|
|
McAteer, MA;
O'Connor, JPB;
Koh, DM;
Leung, HY;
Doran, SJ;
Jauregui-Osoro, M;
Muirhead, N;
... Punwani, S; + view all
(2021)
Introduction to the National Cancer Imaging Translational Accelerator (NCITA): a UK-wide infrastructure for multicentre clinical translation of cancer imaging biomarkers.
British Journal of Cancer
10.1038/s41416-021-01497-5.
(In press).
|
|
|
McCormack, Mary;
Eminowicz, Gemma;
Gallardo, Dolores;
Diez, Patricia;
Farrelly, Laura;
Kent, Christopher;
Hudson, Emma;
... Ledermann, Jonathan Andrew; + view all
(2024)
Induction chemotherapy followed by standard chemoradiotherapy versus standard chemoradiotherapy alone in patients with locally advanced cervical cancer (GCIG INTERLACE): an international, multicentre, randomised phase 3 trial.
The Lancet
, 404
(10462)
pp. 1525-1535.
10.1016/S0140-6736(24)01438-7.
|
|
McDaniel, AS;
Ferraldeschi, R;
Krupa, R;
Landers, M;
Graf, R;
Louw, J;
Jendrisak, A;
... Attard, G; + view all
(2017)
Phenotypic diversity of circulating tumour cells in patients with metastatic castration-resistant prostate cancer.
BJU International
, 120
(5B)
E30-E44.
10.1111/bju.13631.
|
|
|
McDonald, James;
Sayers, Judith;
Anker, Stefan D;
Arends, Jann;
Balstad, Trude;
Baracos, Vickie;
Brown, Leo;
... Cancer Cachexia Endpoints Working, Group; + view all
(2023)
Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series.
Journal of Cachexia, Sarcopenia and Muscle
10.1002/jcsm.13321.
(In press).
|
|
McGranahan, N;
Rosenthal, R;
Hiley, CT;
Rowan, AJ;
Watkins, TBK;
Wilson, GA;
Birkbak, NJ;
... Swanton, C; + view all
(2017)
Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution.
Cell
10.1016/j.cell.2017.10.001.
(In press).
|
|
|
McGranahan, N;
Swanton, C;
(2019)
Neoantigen quality, not quantity.
Science Translational Medicine
, 11
(506)
, Article eaax7918. 10.1126/scitranslmed.aax7918.
|
|
|
McGranahan, N;
Swanton, C;
(2017)
Cancer Evolution Constrained by the Immune Microenvironment.
CELL
, 170
(5)
pp. 825-827.
10.1016/j.cell.2017.08.012.
|
|
McGranahan, N;
Swanton, C;
(2017)
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future.
Cell
, 168
(4)
pp. 613-628.
10.1016/j.cell.2017.01.018.
|
|
|
McGranahan, NL;
(2015)
Mechanisms of cancer evolution and drivers of tumour heterogeneity.
Doctoral thesis , UCL (University College London).
|
|
McLean, BA;
Patel, VB;
Zhabyeyev, P;
Chen, X;
Basu, R;
Wang, F;
Shah, S;
... Oudit, GY; + view all
(2019)
PI3Kα Pathway Inhibition With Doxorubicin Treatment Results in Distinct Biventricular Atrophy and Remodeling With Right Ventricular Dysfunction.
Journal of the American Heart Association
, 8
(9)
, Article e010961. 10.1161/JAHA.118.010961.
|
|
|
McLeavy, L;
Rahman, B;
Kristeleit, R;
Ledermann, J;
Lockley, M;
McCormack, M;
Mould, T;
... Lanceley, A; + view all
(2020)
Mainstreamed Genetic Testing in Ovarian Cancer: Patient Experience of the Testing Process.
International Journal of Gynecological Cancer
, 30
(2)
pp. 221-226.
10.1136/ijgc-2019-000630.
|
|
Mears, HV;
Young, GR;
Sanderson, T;
Harvey, R;
Barrett-Rodger, J;
Penn, R;
Cowton, V;
... Bauer, DLV; + view all
(2025)
Emergence of SARS-CoV-2 subgenomic RNAs that enhance viral fitness and immune evasion.
PLoS Biology
, 23
(1)
, Article e3002982. 10.1371/journal.pbio.3002982.
|
|
|
Mehanna, Hisham;
Gaunt, Piers;
Kong, Anthony;
Hartley, Andrew;
Sanghera, Paul;
Forster, Martin;
Sen, Mehmet;
... Nankivell, Paul; + view all
(2024)
CompARE: study protocol for a phase III randomised controlled platform trial comparing alternative regimens for escalating treatment of intermediate and high-risk oropharyngeal cancer.
Trials
, 25
(1)
, Article 50. 10.1186/s13063-023-07881-1.
|
|
Mehanna, H;
Rischin, D;
Wong, SJ;
Gregoire, V;
Ferris, R;
Waldron, J;
Le, Q-T;
... Porceddu, S; + view all
(2020)
De-Escalation After DE-ESCALATE and RTOG 1016: A Head and Neck Cancer InterGroup Framework for Future De-Escalation Studies.
Journal of Clinical Oncology
, 38
(22)
pp. 2552-2557.
10.1200/JCO.20.00056.
|
|
|
Meinhardt, Anna-Lena;
Munkhbaatar, Enkhtsetseg;
Höckendorf, Ulrike;
Dietzen, Michelle;
Dechant, Marta;
Anton, Martina;
Jacob, Anne;
... Jost, Philipp J; + view all
(2022)
The BCL-2 family member BOK promotes KRAS-driven lung cancer progression in a p53-dependent manner.
Oncogene
10.1038/s41388-021-02161-1.
(In press).
|
|
|
Memon, D;
Schoenfeld, AJ;
Ye, D;
Fromm, G;
Rizvi, H;
Zhang, X;
Keddar, MR;
... Hellmann, MD; + view all
(2024)
Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer.
Cancer Cell
, 42
(2)
pp. 209-224.
10.1016/j.ccell.2023.12.013.
|
|
Mendoza-Naranjo, A;
El-Naggar, A;
Wai, DH;
Mistry, P;
Lazic, N;
Ayala, FR;
da Cunha, IW;
... Sorensen, PH; + view all
(2013)
ERBB4 confers metastatic capacity in Ewing sarcoma.
EMBO Mol Med
, 5
(7)
1019 - 1034.
10.1002/emmm.201202343.
|
|
|
Meng, B;
Kemp, SA;
Papa, G;
Datir, R;
Ferreira, IATM;
Marelli, S;
Harvey, WT;
... Gupta, RK; + view all
(2021)
Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7.
Cell Reports
, 35
(13)
, Article 109292. 10.1016/j.celrep.2021.109292.
|
|
|
Meric-Bernstam, F;
Hurwitz, H;
Raghav, KPS;
McWilliams, RR;
Fakih, M;
VanderWalde, A;
Swanton, C;
... Hainsworth, J; + view all
(2019)
Pertuzumab plus trastuzumab for HER2-amplified metastatic colorectal cancer (MyPathway): an updated report from a multicentre, open-label, phase 2a, multiple basket study.
Lancet Oncology
, 20
(4)
pp. 518-530.
10.1016/S1470-2045(18)30904-5.
|
|
Merry, Eve;
Kesmez, Ronas Taner;
Yu, Tamara;
Flynn, Michael;
Ledermann, Jonathan;
Lockley, Michelle;
Macdonald, Nicola;
... Miller, Rowan; + view all
(2024)
A multicenter retrospective study to assess feasibility, safety and efficacy of first-line carboplatin-paclitaxel versus carboplatin monotherapy in a frail, elderly epithelial ovarian cancer population.
International Journal of Gynecological Cancer
10.1136/ijgc-2024-005394.
(In press).
|
|
|
Mesquita, B;
Rothwell, DG;
Burt, DJ;
Chemi, F;
Fernandez-Gutierrez, F;
Slane-Tan, D;
Antonello, J;
... Brady, G; + view all
(2017)
Molecular analysis of single circulating tumour cells following long-term storage of clinical samples.
Molecular Oncology
, 11
(12)
pp. 1687-1697.
10.1002/1878-0261.12113.
|
|
|
Messaoudene, M;
Mourikis, TP;
Michels, J;
Fu, Y;
Bonvalet, M;
Lacroix-Trikki, M;
Routy, B;
... Zitvogel, L; + view all
(2019)
T-cell bispecific antibodies in node-positive breast cancer: novel therapeutic avenue for MHC class I loss variants.
Annals of Oncology
, 30
(6)
pp. 934-944.
10.1093/annonc/mdz112.
|
|
Meyer, Tim;
Caplin, Martyn;
Khan, Mohid S;
Toumpanakis, Christos;
Shetty, Shishir;
Ramage, John K;
Houchard, Aude;
... Shah, Tahir; + view all
(2022)
Circulating tumor cells and tumor biomarkers in functional midgut neuroendocrine tumors.
Journal of Neuroendocrinology
, 34
(4)
, Article e13096. 10.1111/jne.13096.
|
|
Meyer, Tim;
Galani, Sevasti;
Lopes, Andre;
Vogel, Arndt;
(2023)
Aetiology of liver disease and response to immune checkpoint inhibitors: an updated meta-analysis confirms benefit in those with non-viral liver disease.
Journal of Hepatology
, 79
(2)
e73-e76.
10.1016/j.jhep.2023.04.012.
|
|
Meyer, T;
Fox, R;
Ma, YT;
Ross, PJ;
James, MW;
Sturgess, R;
Stubbs, C;
... Palmer, DH; + view all
(2017)
Sorafenib in combination with transarterial chemoembolisation in patients with unresectable hepatocellular carcinoma (TACE 2): a randomised placebo-controlled, double-blind, phase 3 trial.
The Lancet Gastroenterology and Hepatology
, 2
(8)
pp. 565-575.
10.1016/S2468-1253(17)30156-5.
|
|
Meyer, T;
Palmer, DH;
Cheng, A-L;
Hocke, J;
Loembé, A-B;
Yen, C-J;
(2017)
mRECIST to predict survival in advanced hepatocellular carcinoma: Analysis of two randomised phase II trials comparing nintedanib vs sorafenib.
Liver International
, 37
(7)
pp. 1047-1055.
10.1111/liv.13359.
|
|
Michael, Agnieszka;
Wilson, William;
Sunshine, Sunny;
Annels, Nicola;
Harrop, Richard;
Blount, Daniel;
Pandha, Hardev;
... Ledermann, Jonathan; + view all
(2024)
A randomized phase II trial to examine modified vaccinia Ankara-5T4 vaccine in patients with relapsed asymptomatic ovarian cancer (TRIOC).
International Journal of Gynecologic Cancer
10.1136/ijgc-2023-005200.
(In press).
|
|
Michelozzi, Ilaria M;
Gomez-Castaneda, Eduardo;
Pohle, Ruben VC;
Cardoso Rodriguez, Ferran;
Sufi, Jahangir;
Puigdevall-Costa, Pau;
Subramaniyam, Meera;
... Giustacchini, Alice; + view all
(2022)
Activation priming and cytokine polyfunctionality modulate the enhanced functionality of low-affinity CD19 CAR T cells.
Blood Advances
10.1182/bloodadvances.2022008490.
(In press).
|
|
Middleton, G;
Fletcher, P;
Popat, S;
Savage, J;
Summers, Y;
Greystoke, A;
Gilligan, D;
... Billingham, L; + view all
(2020)
The National Lung Matrix Trial of personalized therapy in lung cancer.
Nature
, 583
(7818)
pp. 807-812.
10.1038/s41586-020-2481-8.
|
|
Milani, A;
Kristeleit, R;
McCormack, M;
Raja, F;
Luvero, D;
Widschwendter, M;
MacDonald, N;
... Ledermann, JA; + view all
(2017)
Switching from standard to dose-dense chemotherapy in front-line treatment of advanced ovarian cancer: a retrospective study of feasibility and efficacy.
ESMO Open
, 1
(6)
, Article e000117. 10.1136/esmoopen-2016-000117.
|
|
Miles, A;
Taylor, SA;
Evans, REC;
Halligan, S;
Beare, S;
Bridgewater, J;
Goh, V;
... Yu, D; + view all
(2019)
Patient preferences for whole-body MRI or conventional staging pathways in lung and colorectal cancer: a discrete choice experiment.
European Radiology
, 29
(7)
pp. 3889-3900.
10.1007/s00330-019-06153-4.
|
|
|
Miller, Rowan E;
Elyashiv, Osnat;
El-Shakankery, Karim H;
Ledermann, Jonathan A;
(2022)
Ovarian Cancer Therapy: Homologous Recombination Deficiency as a Predictive Biomarker of Response to PARP Inhibitors.
OncoTargets and Therapy
, 15
pp. 1105-1117.
10.2147/ott.s272199.
|
|
Miller, R;
Devlin, M-J;
Brown, NF;
Grunewald, T;
McCormack, M;
Lockley, M;
Ledermann, JA;
... Kristeleit, RS; + view all
(2017)
Outcome of patients with advanced endometrial and cervical cancer treated in a phase 1 unit.
Presented at: 2017 Annual Meeting of the American Society of Clinical Oncology (ASCO), Chicago, IL, USA.
|
|
|
Miller, RE;
Brown, NE;
Speirs, A;
Shaw, HM;
Adeleke, S;
Gougis, P;
Bennett, P;
... Kristeleit, RS; + view all
(2016)
The use of next generation sequencing (NGS) to guide patient selection for phase 1 clinical trials.
Annals of Oncology
, 27
(Suppl 6)
pp. 114-135.
10.1093/annonc/mdw368.44.
|
|
Miller, RE;
Devlin, M;
Brown, N;
Woo, K;
Grunewald, T;
Speirs, A;
Mitchison, M;
... Kristeleit, R; + view all
(2017)
Guidance by molecular selection improves the outcome of early phase treatment for gynecological (GYN) cancers.
Presented at: AACR Annual Meeting 2017, Washington, D.C., USA.
|
|
Miranda, E;
Maya Pineda, H;
Öberg, D;
Cherubini, G;
Garate, Z;
Lemoine, NR;
Halldén, G;
(2012)
Adenovirus-Mediated Sensitization to the Cytotoxic Drugs Docetaxel and Mitoxantrone Is Dependent on Regulatory Domains in the E1ACR1 Gene-Region.
PLoS ONE
, 7
(10)
, Article e46617. 10.1371/journal.pone.0046617.
|
|
|
Mitchell, TJ;
Turajlic, S;
Rowan, A;
Nicol, D;
Farmery, JHR;
O'Brien, T;
Martincorena, I;
... Campbell, PJ; + view all
(2018)
Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal.
Cell
, 173
(3)
, Article e17. 10.1016/j.cell.2018.02.020.
|
|
|
Molnar, Janos;
Poti, Adam;
Pipek, Orsolya;
Krzystanek, Marcin;
Kanu, Nnennaya;
Swanton, Charles;
Tusnady, Gabor E;
... Szuets, David; + view all
(2014)
The Genome of the Chicken DT40 Bursal Lymphoma Cell Line.
G3-GENES GENOMES GENETICS
, 4
(11)
pp. 2231-2240.
10.1534/g3.114.013482.
|
|
|
Moniz, LS;
Surinova, S;
Ghazaly, E;
Velasco, LG;
Haider, S;
Rodriguez-Prados, JC;
Berenjeno, IM;
... Vanhaesebroeck, B; + view all
(2017)
Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate.
Scientific Reports
, 7
(39985)
10.1038/srep39985.
|
|
|
Montagner, M;
Bhome, R;
Hooper, S;
Chakravarty, P;
Qin, X;
Sufi, J;
Bhargava, A;
... Sahai, E; + view all
(2020)
Crosstalk with lung epithelial cells regulates Sfrp2-mediated latency in breast cancer dissemination.
Nature Cell Biology
, 22
pp. 289-296.
10.1038/s41556-020-0474-3.
|
|
Montgomery, HE;
Haines, A;
Marlow, N;
Pearson, G;
Mythen, MG;
Grocott, MPW;
Swanton, C;
(2017)
The future of UK healthcare: problems and potential solutions to a system in crisis.
[Review].
Annals of Oncology
, 28
(8)
pp. 1751-1755.
10.1093/annonc/mdx136.
|
|
Monypenny, J;
Milewicz, H;
Flores-Borja, F;
Weitsman, G;
Cheung, A;
Chowdhury, R;
Burgoyne, T;
... Ng, T; + view all
(2018)
ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation.
Cell Reports
, 24
(3)
pp. 630-641.
10.1016/j.celrep.2018.06.066.
|
|
|
Moorcraft, SY;
Jones, T;
Walker, BA;
Ladas, G;
Kalaitzaki, E;
Yuan, L;
Begum, R;
... Chau, I; + view all
(2017)
Molecular profiling of colorectal pulmonary metastases and primary tumours: implications for targeted treatment.
Oncotarget
, 8
(39)
pp. 64999-65008.
10.18632/oncotarget.17048.
|
|
Moore, DA;
Benafif, S;
Poskitt, B;
Argue, S;
Lee, SM;
Ahmad, T;
Papadatos-Pastos, D;
... Forster, MD; + view all
(2021)
Optimising fusion detection through sequential DNA and RNA molecular profiling of non-small cell lung cancer.
Lung Cancer
, 161
pp. 55-59.
10.1016/j.lungcan.2021.08.008.
|
|
Moore, KN;
Angelergues, A;
Konecny, GE;
García, Y;
Banerjee, S;
Lorusso, D;
Lee, JY;
... Van Gorp, T; + view all
(2023)
Mirvetuximab Soravtansine in FRα-Positive, Platinum-Resistant Ovarian Cancer.
New England Journal of Medicine
, 389
(23)
pp. 2162-2174.
10.1056/NEJMoa2309169.
|
|
Moore, DA;
Kushnir, M;
Mak, G;
Winter, H;
Curiel, T;
Voskoboynik, M;
Moschetta, M;
... Arkenau, HT; + view all
(2019)
Prospective analysis of 895 patients on a UK Genomics Review Board.
ESMO Open
, 4
(2)
, Article e000469. 10.1136/esmoopen-2018-000469.
|
|
|
Moore, DA;
Sereno, M;
Das, M;
Baena Acevedo, JD;
Sinnadurai, S;
Smith, C;
McSweeney, A;
... Le Quesne, J; + view all
(2019)
In situ growth in early lung adenocarcinoma may represent precursor growth or invasive clone outgrowth-a clinically relevant distinction.
Modern Pathology
10.1038/s41379-019-0257-1.
(In press).
|
|
Moore, KM;
Desai, A;
Delgado, BDL;
Trabulo, SMD;
Reader, C;
Brown, NF;
Murray, ER;
... Marshall, JF; + view all
(2020)
Integrin αvβ6-specific therapy for pancreatic cancer developed from foot-and-mouth-disease virus.
Theranostics
, 10
(7)
pp. 2930-2942.
10.7150/thno.38702.
|
|
|
Morales Torres, C;
Wu, MY;
Hobor, S;
Wainwright, EN;
Martin, MJ;
Patel, H;
Grey, W;
... Scaffidi, P; + view all
(2020)
Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis.
Nature Communications
, 11
(1)
, Article 1792. 10.1038/s41467-020-15615-z.
|
|
|
Moreno, V;
Greil, R;
Yachnin, J;
Majem, M;
Wermke, M;
Arkenau, HT;
Basque, JR;
... Giovannini, M; + view all
(2021)
Pharmacokinetics and safety of capmatinib with food in patients with MET-dysregulated advanced solid tumors.
Clinical Therapeutics
10.1016/j.clinthera.2021.04.006.
|
|
|
Morgan, Robert D;
Clamp, Andrew R;
Barnes, Bethany M;
Timms, Kirsten;
Schlecht, Helene;
Yarram-Smith, Laura;
Wallis, Yvonne;
... Jayson, Gordon C; + view all
(2023)
Homologous recombination deficiency in newly diagnosed FIGO stage III/IV high-grade epithelial ovarian cancer: a multi-national observational study.
International Journal of Gynecological Cancer
10.1136/ijgc-2022-004211.
(In press).
|
|
|
Morka, N;
Simpson, BS;
Emberton, M;
Norris, JM;
(2021)
Re: Giorgio Gandaglia, Guillaume Ploussard, Massimo Valerio, et al. Prognostic Implications of Multiparametric Magnetic Resonance Imaging and Concomitant Systematic Biopsy in Predicting Biochemical Recurrence After Radical Prostatectomy in Prostate Cancer Patients Diagnosed with Magnetic Resonance Imaging–targeted Biopsy. Eur Urol Oncol 2020;7:739–47.
European Urology Oncology
, 4
(1)
pp. 127-128.
10.1016/j.euo.2020.12.015.
|
|
Morka, N;
Simpson, BS;
Ball, R;
Freeman, A;
Kirkham, A;
Kelly, D;
Whitaker, HC;
... Norris, JM; + view all
(2021)
Clinical outcomes associated with prostate cancer conspicuity on biparametric and multiparametric MRI: a protocol for a systematic review and meta-analysis of biochemical recurrence following radical prostatectomy.
BMJ Open
, 11
(5)
, Article e047664. 10.1136/bmjopen-2020-047664.
|
|
|
Morotti, M;
Albukhari, A;
Alsaadi, A;
Artibani, M;
Brenton, JD;
Curbishley, SM;
Dong, T;
... Ahmed, AA; + view all
(2021)
Promises and challenges of adoptive T-cell therapies for solid tumours.
British Journal of Cancer
10.1038/s41416-021-01353-6.
(In press).
|
|
|
Morrissy, AS;
Cavalli, FMG;
Remke, M;
Ramaswamy, V;
Shih, DJH;
Holgado, BL;
Farooq, H;
... Taylor, MD; + view all
(2017)
Spatial heterogeneity in medulloblastoma.
Nature Genetics
, 49
(5)
pp. 780-788.
10.1038/ng.3838.
|
|
|
Morschhauser, F;
Machiels, J-P;
Salles, G;
Rottey, S;
Rule, SAJ;
Cunningham, D;
Peyrade, F;
... Awada, A; + view all
(2020)
On-Target Pharmacodynamic Activity of the PI3K Inhibitor Copanlisib in Paired Biopsies from Patients with Malignant Lymphoma and Advanced Solid Tumors.
Molecular Cancer Therapeutics
, 19
(2)
pp. 468-478.
10.1158/1535-7163.MCT-19-0466.
|
|
Moschetta, M;
Mak, G;
Hauser, J;
Davies, C;
Uccello, M;
Arkenau, HT;
(2017)
Dabrafenib and trametinib activity in a patient with BRAF V600E mutated and microsatellite instability high (MSI-H) metastatic endometrial cancer.
Experimental Hematology & Oncology
, 6
(1)
, Article 1. 10.1186/s40164-016-0061-2.
|
|
|
Mourikis, TP;
Benedetti, L;
Foxall, E;
Temelkovski, D;
Nulsen, J;
Perner, J;
Cereda, M;
... Ciccarelli, FD; + view all
(2019)
Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma.
Nature Communications
, 10
(1)
, Article 3101. 10.1038/s41467-019-10898-3.
|
|
|
Mueller, V;
Wardley, A;
Paplomata, E;
Hamilton, E;
Zelnak, A;
Fehrenbacher, L;
Jakobsen, E;
... Gelmon, K; + view all
(2021)
Preservation of quality of life in patients with human epidermal growth factor receptor 2–positive metastatic breast cancer treated with tucatinib or placebo when added to trastuzumab and capecitabine (HER2CLIMB trial).
European Journal of Cancer
, 153
pp. 223-233.
10.1016/j.ejca.2021.05.025.
|
|
|
Muliaditan, T;
Caron, J;
Okesola, M;
Opzoomer, JW;
Kosti, P;
Georgouli, M;
Gordon, P;
... Arnold, JN; + view all
(2018)
Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis.
Nature Communications
, 9
, Article 2951. 10.1038/s41467-018-05346-7.
|
|
|
Munkhbaatar, E;
Dietzen, M;
Agrawal, D;
Anton, M;
Jesinghaus, M;
Boxberg, M;
Pfarr, N;
... Jost, PJ; + view all
(2020)
MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically.
Nature Communications
, 11
(1)
, Article 4527. 10.1038/s41467-020-18372-1.
|
|
|
Muñoz-Martínez, S;
Sapena, V;
Forner, A;
Nault, J-C;
Sapisochin, G;
Rimassa, L;
Sangro, B;
... Reig, M; + view all
(2021)
Assessing the impact of COVID-19 on liver cancer management (CERO-19).
JHEP Reports
, Article 100260. 10.1016/j.jhepr.2021.100260.
(In press).
|
|
|
Muñoz-Ruiz, Miguel;
Llorian, Miriam;
D'Antuono, Rocco;
Pavlova, Anna;
Mavrigiannaki, Anna Maria;
McKenzie, Duncan;
García-Cassani, Bethania;
... Hayday, Adrian C; + view all
(2023)
Interferon-g-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit acute contact dermatitis.
Journal of Allergy and Clinical Immunology
10.1016/j.jaci.2023.07.015.
(In press).
|
|
Mustapha, R;
Ng, K;
Monypenny, J;
Ng, T;
(2021)
Insights Into Unveiling a Potential Role of Tertiary Lymphoid Structures in Metastasis.
Frontiers in Molecular Biosciences
, 8
10.3389/fmolb.2021.661516.
|
N
|
Nagano, K;
Akpan, A;
Warnasuriya, G;
Corless, S;
Totty, N;
Yang, A;
Stein, R;
... Naaby-Hansen, S; + view all
(2012)
Functional Proteomic Analysis of Long-term Growth Factor Stimulation and Receptor Tyrosine Kinase Coactivation in Swiss 3T3 Fibroblasts.
Molecular & Cellular Proteomics
, 11
(12)
pp. 1690-1708.
10.1074/mcp.M112.019778.
|
|
|
Naing, A;
Thistlethwaite, F;
De Vries, EGE;
Eskens, FALM;
Uboha, N;
Ott, PA;
Lorusso, P;
... Spira, A; + view all
(2021)
CX-072 (pacmilimab), a Probody® PD-L1 inhibitor, in advanced or recurrent solid tumors (PROCLAIM-CX-072): an open-label dose-finding and first-in-human study.
Journal for ImmunoTherapy of Cancer
, 9
(7)
, Article e002447. 10.1136/jitc-2021-002447.
|
|
|
Nannini, F;
Parekh, F;
Wawrzyniecka, P;
Mekkaoui, L;
Righi, M;
Dastjerdi, FV;
Yeung, J;
... Pule, M; + view all
(2020)
A primer set for the rapid isolation of scFv fragments against cell surface antigens from immunised rats.
Scientific Reports
, 10
, Article 19168. 10.1038/s41598-020-76069-3.
|
|
|
Naumann, RW;
Hollebecque, A;
Meyer, T;
Devlin, M-J;
Oaknin, A;
Kerger, J;
López-Picazo, JM;
... Moore, KN; + view all
(2019)
Safety and Efficacy of Nivolumab Monotherapy in Recurrent or Metastatic Cervical, Vaginal, or Vulvar Carcinoma: Results From the Phase I/II CheckMate 358 Trial.
Journal of Clinical Oncology
, 37
(31)
pp. 2825-2834.
10.1200/JCO.19.00739.
|
|
Naxerova, K;
Reiter, JG;
Brachtel, E;
Lennerz, JK;
van de Wetering, M;
Rowan, A;
Cai, T;
... Jain, RK; + view all
(2017)
Origins of lymphatic and distant metastases in human colorectal cancer.
Science
, 357
(6346)
pp. 55-60.
10.1126/science.aai8515.
|
|
|
Neal, RD;
Johnson, P;
Clarke, CA;
Hamilton, SA;
Zhang, N;
Kumar, H;
Swanton, C;
(2022)
Cell-Free DNA–Based Multi-Cancer Early Detection Test in an Asymptomatic Screening Population (NHS-Galleri): Design of a Pragmatic, Prospective Randomised Controlled Trial.
Cancers
, 14
(19)
, Article 4818. 10.3390/cancers14194818.
|
|
Neoptolemos, JP;
Palmer, DH;
Ghaneh, P;
Psarelli, EE;
Valle, JW;
Halloran, CM;
Faluyi, O;
... European Study Group for Pancreatic Cancer, .; + view all
(2017)
Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial.
Lancet
, 389
(10073)
pp. 1011-1024.
10.1016/S0140-6736(16)32409-6.
|
|
|
Ng, Kenrick;
Metcalf, Rob;
Sacco, Joseph;
Kong, Anthony;
Wheeler, Graham;
Forsyth, Sharon;
Bhat, Reshma;
... Forster, Martin; + view all
(2023)
Protocol for the EACH trial: a multicentre phase II study evaluating the safety and antitumour activity of the combination of avelumab, an anti-PD-L1 agent, and cetuximab, as any line treatment for patients with recurrent/metastatic head and neck squamous cell cancer (HNSCC) in the UK.
BMJ Open
, 13
(11)
, Article e070391. 10.1136/bmjopen-2022-070391.
|
|
Ng, Kevin W;
Boumelha, Jesse;
Enfield, Katey SS;
Almagro, Jorge;
Cha, Hongui;
Pich, Oriol;
Karasaki, Takahiro;
... Kassiotis, George; + view all
(2023)
Antibodies against endogenous retroviruses promote lung cancer immunotherapy.
Nature
10.1038/s41586-023-05771-9.
(In press).
|
|
Ng, Kevin W;
Faulkner, Nikhil;
Finsterbusch, Katja;
Wu, Mary;
Harvey, Ruth;
Hussain, Saira;
Greco, Maria;
... Kassiotis, George; + view all
(2022)
SARS-CoV-2 S2–targeted vaccination elicits broadly neutralizing antibodies.
Science Translational Medicine
, 14
(655)
, Article eabn3715. 10.1126/scitranslmed.abn3715.
|
|
|
Ng, KW;
Faulkner, N;
Cornish, GH;
Rosa, A;
Harvey, R;
Hussain, S;
Ulferts, R;
... Kassiotis, G; + view all
(2020)
Preexisting and de novo humoral immunity to SARS-CoV-2 in humans.
Science
, Article eabe1107. 10.1126/science.abe1107.
(In press).
|
|
|
Ng, Q.S.;
(2008)
Therapeutic targeting and clinical assessment of the tumour vasculature.
Doctoral thesis , University of London.
|
|
|
Nicholls, J.;
(2006)
Investigating protein complexes that are involved in the function and regulation of the human INK4a/ARF locus.
Doctoral thesis , University of London.
|
|
Nicum, Shibani;
Blagden, Sarah P;
(2022)
PARPs: All for One and One for All? Enhancing Diversity in Clinical Trials.
Clinical Cancer Research
, 28
(11)
pp. 2201-2203.
10.1158/1078-0432.CCR-22-0442.
|
|
Nicum, Shibani;
McGregor, Naomi;
Austin, Rachel;
Collins, Linda;
Dutton, Susan;
McNeish, Iain;
Glasspool, Rosalind;
... Mansouri, Anita; + view all
(2024)
Results of a randomised Phase II trial of olaparib, chemotherapy or olaparib and cediranib in patients with platinum-resistant ovarian cancer.
British Journal of Cancer
10.1038/s41416-023-02567-6.
(In press).
|
|
Nile, DL;
Rae, C;
Hyndman, IJ;
Gaze, MN;
Mairs, RJ;
(2016)
An evaluation in vitro of PARP-1 inhibitors, rucaparib and olaparib, as radiosensitisers for the treatment of neuroblastoma.
BMC Cancer
, 16
(1)
, Article 621. 10.1186/s12885-016-2656-8.
|
|
|
Nile, Donna L;
Rae, Colin;
Walker, David J;
Waddington, Joe Canning;
Vincent, Isabel;
Burgess, Karl;
Gaze, Mark N;
... Chalmers, Anthony J; + view all
(2021)
Inhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells.
Cancer and Metabolism
, 9
, Article 24. 10.1186/s40170-021-00258-5.
|
|
Noorani, Imran;
Luebeck, Jens;
Rowan, Andrew;
Gronroos, Eva;
Barbe, Vittorio;
Fabian, Mark;
Nicoll, James;
... Swanton, Charles; + view all
(2024)
Oncogenic extrachromosomal DNA identification using whole-genome sequencing from formalin-fixed glioblastomas.
Annals of Oncology
, 35
(6)
pp. 570-573.
10.1016/j.annonc.2024.03.008.
|
|
Nordstrom, BL;
Oguz, M;
Chu, BC;
Ouwens, M;
Arkenau, H-T;
Klein, AB;
(2020)
Effectiveness of durvalumab versus chemotherapy in metastatic urothelial cancer: an observational, indirect comparison.
Journal of Comparative Effectiveness Research
, 9
(3)
pp. 191-199.
10.2217/cer-2019-0163.
|
|
|
Norris, JM;
Carmona Echeverria, LM;
Simpson, BS;
Ball, R;
Freeman, A;
Kelly, D;
Kirkham, A;
... Emberton, M; + view all
(2021)
Conspicuity of cribriform prostate cancer on multiparametric magnetic resonance imaging: the jury is still out.
BJU International
, 127
(2)
pp. 169-170.
10.1111/bju.15295.
|
|
Norris, JM;
Simpson, BS;
Ball, R;
Freeman, A;
Kirkham, A;
Parry, MA;
Moore, CM;
... Emberton, M; + view all
(2021)
A Modified Newcastle-Ottawa Scale for Assessment of Study Quality in Genetic Urological Research.
European Urology
, 79
(3)
pp. 325-326.
10.1016/j.eururo.2020.12.017.
|
|
Norris, JM;
Carmona Echeverria, LM;
Simpson, BS;
Allen, C;
Ball, R;
Freeman, A;
Kelly, D;
... Emberton, M; + view all
(2020)
Prostate Cancer Visibility on Multiparametric Magnetic Resonance Imaging: High Gleason Grade and Increased Tumour Volume are Not the Only Important Histopathological Features.
BJU International
, 126
(2)
pp. 237-239.
10.1111/bju.15085.
|
|
Norris, JM;
Carmona Echeverria, LM;
Simpson, BS;
Ball, R;
Freeman, A;
Kelly, D;
Kirkham, A;
... Emberton, M; + view all
(2020)
Histopathological features of prostate cancer conspicuity on multiparametric MRI: protocol for a systematic review and meta-analysis.
BMJ Open
, 10
(10)
, Article e039735. 10.1136/bmjopen-2020-039735.
|
|
|
Norris, JM;
Simpson, BS;
Freeman, A;
Kirkham, A;
Whitaker, HC;
Emberton, M;
(2020)
Conspicuity of prostate cancer on multiparametric magnetic resonance imaging: A cross-disciplinary translational hypothesis.
The FASEB Journal
, 34
pp. 14150-14159.
10.1096/fj.202001466R.
|
|
|
Norris, JM;
Simpson, BS;
Parry, MA;
Allen, C;
Ball, R;
Freeman, A;
Kelly, D;
... Emberton, M; + view all
(2020)
Genetic Landscape of Prostate Cancer Conspicuity on Multiparametric Magnetic Resonance Imaging: A Systematic Review and Bioinformatic Analysis.
European Urology Open Science
, 20
pp. 37-47.
10.1016/j.euros.2020.06.006.
|
|
|
Norris, JM;
Simpson, BS;
Parry, MA;
Allen, C;
Ball, R;
Freeman, A;
Kelly, D;
... Emberton, M; + view all
(2020)
Genetic landscape of prostate cancer conspicuity on multiparametric MRI: a protocol for a systematic review and bioinformatic analysis.
BMJ Open
, 10
(1)
, Article e034611. 10.1136/bmjopen-2019-034611.
|
|
|
Norris, JM;
Simpson, BS;
Parry, MA;
Kasivisvanathan, V;
Allen, C;
Ball, R;
Freeman, A;
... Emberton, M; + view all
(2020)
Genetic correlates of prostate cancer visibility (and invisibility) on mpMRI: It's time to take stock.
BJU International
, 125
(3)
pp. 340-342.
10.1111/bju.14919.
|
|
Nuttall Musson, Ellen;
Miller, Rowan E;
Mansour, Marc R;
Lockley, Michelle;
Ledermann, Jonathan A;
Payne, Elspeth M;
(2023)
Monitoring clone dynamics and reversibility in clonal haematopoiesis and myelodysplastic neoplasm associated with PARP inhibitor therapy-a role for early monitoring and intervention.
Leukemia
10.1038/s41375-023-02040-6.
(In press).
|
O
|
O'Connor, E;
Fourier, C;
Ran, C;
Sivakumar, P;
Liesecke, F;
Southgate, L;
Harder, AVE;
... Belin, AC; + view all
(2021)
Genome-Wide Association Study Identifies Risk Loci for Cluster Headache.
Annals of Neurology
, 90
(2)
pp. 193-202.
10.1002/ana.26150.
|
|
O'Connor, E;
Simpson, BS;
Houlden, H;
Vandrovcova, J;
Matharu, M;
(2020)
Prevalence of familial cluster headache: a systematic review and meta-analysis.
The Journal of Headache and Pain
, 21
, Article 37. 10.1186/s10194-020-01101-w.
|
|
|
O'Connor, JP;
Aboagye, EO;
Adams, JE;
Aerts, HJ;
Barrington, SF;
Beer, AJ;
Boellaard, R;
... Waterton, JC; + view all
(2016)
Imaging biomarker roadmap for cancer studies.
Nat Rev Clin Oncol
10.1038/nrclinonc.2016.162.
(In press).
|
|
O'Donnell, PH;
Arkenau, HT;
Sridhar, SS;
Ong, M;
Drakaki, A;
Spira, A;
Zhang, J;
... Friedlander, T; + view all
(2020)
Patient‐reported outcomes and inflammatory biomarkers in patients with locally advanced/metastatic urothelial carcinoma treated with durvalumab in phase 1/2 dose‐escalation study 1108.
Cancer
, 126
(2)
pp. 432-443.
10.1002/cncr.32532.
|
|
O'Malley, David M;
Oza, Amit M;
Lorusso, Domenica;
Aghajanian, Carol;
Oaknin, Ana;
Dean, Andrew;
Colombo, Nicoletta;
... Coleman, Robert L; + view all
(2022)
Clinical and molecular characteristics of ARIEL3 patients who derived exceptional benefit from rucaparib maintenance treatment for high-grade ovarian carcinoma.
Gynecologic Oncology
, 167
(3)
pp. 404-413.
10.1016/j.ygyno.2022.08.021.
|
|
Oakes, T;
Heather, JM;
Best, K;
Byng-Maddick, R;
Husovsky, C;
Ismail, M;
Joshi, K;
... Chain, B; + view all
(2017)
Quantitative Characterization of the T Cell Receptor Repertoire of Naive and Memory subsets Using an Integrated experimental and Computational Pipeline Which Is Robust, economical, and Versatile.
Frontiers in Immunology
, 8
, Article 1267. 10.3389/fimmu.2017.01267.
|
|
|
Oakes, T;
Popple, AL;
Williams, J;
Best, K;
Heather, JM;
Ismail, M;
Maxwell, G;
... Chain, B; + view all
(2017)
The T Cell Response to the Contact Sensitizer Paraphenylenediamine Is Characterized by a Polyclonal Diverse Repertoire of Antigen-Specific Receptors.
Frontiers in Immunology
, 8
, Article 162. 10.3389/fimmu.2017.00162.
|
|
|
Oaknin, A;
Bosse, TJ;
Creutzber, CL;
Giornelli, G;
Harter, P;
Joly, F;
Lorusso, D;
... ESMO Guidelines Committee, .; + view all
(2022)
Endometrial cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
Annals of Oncology
, 33
(9)
pp. 860-877.
10.1016/j.annonc.2022.05.009.
|
|
Oaknin, A;
Oza, A;
Tinker, A;
Ray-Coquard, I;
Coleman, R;
O'Malley, D;
Shapira-Frommer, R;
... Kristeleit, RS; + view all
(2017)
Integrated efficacy and safety analysis of the poly(ADP-ribose) polymerase (PARP) inhibitor rucaparib in patients (pts) with high-grade ovarian carcinoma (HGOC).
In:
ECCO: 2017 European Cancer Congress. Abstract Book.
(pp. S95-S95).
Elsevier
|
|
Ogunlade, O;
Ho, J;
Kalber, T;
Hynds, R;
Zhang, E;
Janes, SM;
Birchall, M;
... Beard, P; + view all
(2019)
Monitoring neovascularization and integration of decellularized human scaffolds using photoacoustic imaging.
Photoacoustics
, 13
pp. 76-84.
10.1016/j.pacs.2019.01.001.
(In press).
|
|
|
Ohnmacht, SA;
Marchetti, C;
Gunaratnam, M;
Besser, RJ;
Haider, SM;
Di Vita, G;
Lowe, HL;
... Neidle, S; + view all
(2015)
A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer.
Scientific Reports
, 5
, Article 11385. 10.1038/srep11385.
|
|
|
Okkenhaug, K;
Ali, K;
Vanhaesebroeck, B;
(2007)
Antigen receptor signalling: a distinctive role for the p110delta isoform of PI3K.
Trends in Immunology
, 28
(2)
80 - 87.
10.1016/j.it.2006.12.007.
|
|
|
Okkenhaug, K;
Graupera, M;
Vanhaesebroeck, B;
(2016)
Targeting PI3K in Cancer: Impact on Tumor Cells, Their Protective Stroma, Angiogenesis, and Immunotherapy.
Cancer Discovery
, 6
(10)
pp. 1090-1105.
10.1158/2159-8290.CD-16-0716.
|
|
|
Olmedo, ME;
Forster, M;
Moreno, V;
Lopez-Criado, MP;
Brana, I;
Flynn, M;
Doger, B;
... Calvo, E; + view all
(2021)
Efficacy and safety of lurbinectedin and doxorubicin in relapsed small cell lung cancer. Results from an expansion cohort of a phase I study.
Investigational New Drugs
10.1007/s10637-020-01025-x.
(In press).
|
|
|
Opzoomer, JW;
Anstee, JE;
Dean, I;
Hill, EJ;
Bouybayoune, I;
Caron, J;
Muliaditan, T;
... Arnold, JN; + view all
(2021)
Macrophages orchestrate the expansion of a proangiogenic perivascular niche during cancer progression.
Science Advances
, 7
(45)
, Article eabg9518. 10.1126/sciadv.abg9518.
|
|
|
Opzoomer, JW;
Timms, JA;
Blighe, K;
Mourikis, TP;
Chapuis, N;
Bekoe, R;
Kareemaghay, S;
... Kordasti, S; + view all
(2021)
ImmunoCluster provides a computational framework for the non-specialist to profile high- dimensional cytometry data.
eLife
, 10
, Article e62915. 10.7554/eLife.62915.
(In press).
|
|
Orgaz, JL;
Crosas-Molist, E;
Sadok, A;
Perdrix-Rosell, A;
Maiques, O;
Rodriguez-Hernandez, I;
Monger, J;
... Sanz-Moreno, V; + view all
(2020)
Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance.
Cancer Cell
, 37
(1)
85-103.e9.
10.1016/j.ccell.2019.12.003.
|
|
|
Orr, Jessica C;
Laali, Asma;
Durrenberger, Pascal F;
Lazarus, Kyren A;
El Mdawar, Marie-Belle;
Janes, Sam M;
Hynds, Robert E;
(2024)
A lentiviral toolkit to monitor airway epithelial cell differentiation using bioluminescence.
American Journal of Physiology-Lung Cellular and Molecular Physiology
, 327
(4)
L587-L599.
10.1152/ajplung.00047.2024.
|
|
Orr, JC;
Hynds, RE;
(2021)
Stem Cell-Derived Respiratory Epithelial Cell Cultures as Human Disease Models.
American Journal of Respiratory Cell and Molecular Biology
10.1165/rcmb.2020-0440TR.
(In press).
|
|
|
Ortiz-Zapater, E;
Lee, RW;
Owen, W;
Weitsman, G;
Fruhwirth, G;
Dunn, RG;
Neat, MJ;
... Santis, G; + view all
(2017)
MET-EGFR dimerization in lung adenocarcinoma is dependent on EGFR mtations and altered by MET kinase inhibition.
PLoS ONE
, 12
(1)
, Article e0170798. 10.1371/journal.pone.0170798.
|
|
|
Owen-Casey, MP;
Sim, R;
Cook, HT;
Roufosse, CA;
Gillmore, JD;
Gilbertson, JA;
Hutchison, CA;
(2014)
Value of antibodies to free light chains in immunoperoxidase studies of renal biopsies.
J Clin Pathol
, 67
(8)
pp. 661-666.
10.1136/jclinpath-2014-202231.
|
|
|
Oxley, Samuel;
Kalra, Ashwin;
Sideris, Michail;
Itzkowitz, Nicole;
Evans, Olivia;
Atakpa, Emma Christine;
Brentnall, Adam R;
... Manchanda, Ranjit; + view all
(2023)
Impact of Multiple COVID-19 Waves on Gynaecological Cancer Services in the UK.
Cancers
, 15
(4)
, Article 1273. 10.3390/cancers15041273.
|
|
Oza, AM;
Matulonis, UA;
Alvarez Secord, A;
Nemunaitis, J;
Roman, LD;
Blagden, SP;
Banerjee, S;
... Matei, D; + view all
(2020)
A Randomized Phase II Trial of Epigenetic Priming with Guadecitabine and Carboplatin in Platinum-resistant, Recurrent Ovarian Cancer.
Clinical Cancer Research
, 26
(5)
pp. 1009-1016.
10.1158/1078-0432.CCR-19-1638.
|
|
Oza, AM;
Tinker, AV;
Oaknin, A;
Shapira-Frommer, R;
McNeish, IA;
Swisher, EM;
Ray-Coquard, I;
... Kristeleit, RS; + view all
(2017)
Antitumor activity and safety of the PARP inhibitor rucaparib in patients with high-grade ovarian carcinoma and a germline or somatic BRCA1 or BRCA2 mutation: Integrated analysis of data from Study 10 and ARIEL2.
Gynecologic Oncology
, 147
(2)
pp. 267-275.
10.1016/j.ygyno.2017.08.022.
|
|
P
|
Pagano, Domenico;
Home, Philip;
Irs, Alar;
Ledermann, Jonathan;
Curigliano, Giuseppe;
Iwatani, Tsuguo;
Mandrola, John;
(2022)
The path for medical associations to sponsor trustworthy guidelines: is it feasible?
Journal of the Royal Society of Medicine
10.1177/01410768221095240.
(In press).
|
|
Palam, LR;
Mali, RS;
Ramdas, B;
Srivatsan, SN;
Visconte, V;
Tiu, RV;
Vanhaesebroeck, B;
... Kapur, R; + view all
(2018)
Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway.
JCI Insight
, 3
(4)
, Article e94679. 10.1172/jci.insight.94679.
|
|
|
Palles, Claire;
West, Hannah D;
Chew, Edward;
Galavotti, Sara;
Flensburg, Christoffer;
Grolleman, Judith E;
Jansen, Erik AM;
... de Voer, Richarda M; + view all
(2022)
Germline MBD4 deficiency causes a multi-tumor predisposition syndrome.
American Journal of Human Genetics
, 109
(5)
pp. 953-960.
10.1016/j.ajhg.2022.03.018.
|
|
Palmer, DH;
Ma, YT;
Peck-Radosavljevic, M;
Ross, P;
Graham, J;
Fartoux, L;
Deptala, A;
... Meyer, T; + view all
(2018)
A multicentre, open-label, phase-I/randomised phase-II study to evaluate safety, pharmacokinetics, and efficacy of nintedanib vs. sorafenib in European patients with advanced hepatocellular carcinoma.
British Journal of Cancer
, 118
pp. 1162-1168.
10.1038/s41416-018-0051-8.
|
|
Pan, Xiaoxi;
AbdulJabbar, Khalid;
Coelho-Lima, Jose;
Grapa, Anca-Ioana;
Zhang, Hanyun;
Cheung, Alvin Ho Kwan;
Baena, Juvenal;
... Moore, David A; + view all
(2024)
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma.
Nature Cancer
10.1038/s43018-023-00694-w.
|
|
Papastavrou, YR;
(2015)
Use of Multicomponent Non-Rigid Registration to Improve Alignment of Serial Oncological PET/CT Studies.
Doctoral thesis , UCL (University College London).
|
|
|
Papoutsaki, M;
Sidhu, H;
Dikaios, N;
Atkinson, D;
Beale, T;
Morley, S;
Forster, M;
... Punwani, S; + view all
(2018)
Pre-treatment intra- and inter- voxel magnetic resonance diffusion heterogeneity correlates with chemoradiotherapy treatment outcome of patients with head and neck squamous cell carcinoma.
Presented at: Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.
(In press).
|
|
Papoutsaki, M-V;
Sidhu, HS;
Dikaios, N;
Singh, S;
Atkinson, D;
Kanber, B;
Beale, T;
... Punwani, S; + view all
(2021)
Utility of diffusion MRI characteristics of cervical lymph nodes as disease classifier between patients with head and neck squamous cell carcinoma and healthy volunteers.
NMR in Biomedicine
, Article e4587. 10.1002/nbm.4587.
(In press).
|
|
|
Parisi, I;
Tsochatzis, E;
Wijewantha, H;
Rodríguez-Perálvarez, M;
De Luca, L;
Manousou, P;
Fatourou, E;
... Burroughs, AK; + view all
(2014)
Inflammation-based scores do not predict post-transplant recurrence of hepatocellular carcinoma (HCC) in patients within Milan criteria.
Liver Transplantation
, 20
(11)
pp. 1327-1335.
10.1002/lt.23969.
|
|
|
Parker, Peter J;
Brown, Sophie J;
Calleja, Veronique;
Chakravarty, Probir;
Cobbaut, Mathias;
Linch, Mark;
Marshall, Jacqueline JT;
... Watson, Lisa; + view all
(2021)
Equivocal, explicit and emergent actions of PKC isoforms in cancer.
NATURE REVIEWS CANCER
, 21
(1)
pp. 51-63.
10.1038/s41568-020-00310-4.
|
|
Parker, CC;
James, ND;
Brawley, CD;
Clarke, NW;
Hoyle, AP;
Ali, A;
Ritchie, AWS;
... Systemic Therapy for Advanced or Metastatic Prostate cancer, .; + view all
(2018)
Radiotherapy to the primary tumour for newly diagnosed, metastatic prostate cancer (STAMPEDE): a randomised controlled phase 3 trial.
Lancet
, 392
(10162)
pp. 2353-2366.
10.1016/S0140-6736(18)32486-3.
|
|
|
Parker, H;
McIver-Brown, NR;
Davis, ZA;
Parry, M;
Rose-Zerilli, MJJ;
Xochelli, A;
Gibson, J;
... Oscier, DG; + view all
(2018)
CBL-MZ is not a single biological entity: evidence from genomic analysis and prolonged clinical follow-up.
Blood Advances
, 2
(10)
pp. 1116-1119.
10.1182/bloodadvances.2018019760.
|
|
|
Parry, M;
(2018)
Introducing the Metastatic Breast Cancer Project: a novel patient-partnered initiative to accelerate understanding of MBC.
ESMO Open
, 3
(7)
, Article e000452. 10.1136/esmoopen-2018-000452.
|
|
|
Parry, M;
(2018)
Tumor evolution in non-small-cell lung cancer.
ESMO Open
, 3
(6)
, Article e000436. 10.1136/esmoopen-2018-000436.
|
|
|
Parry, MA;
Srivastava, S;
Ali, A;
Cannistraci, A;
Antonello, J;
Barros-Silva, JD;
Ubertini, V;
... Baena, E; + view all
(2019)
Genomic Evaluation of Multiparametric Magnetic Resonance Imaging-visible and -nonvisible Lesions in Clinically Localised Prostate Cancer.
European Urology Oncology
, 2
(1)
pp. 1-11.
10.1016/j.euo.2018.08.005.
|
|
|
Pascall, DJ;
Vink, E;
Blacow, R;
Bulteel, N;
Campbell, A;
Campbell, R;
Clifford, S;
... Carabelli, AM; + view all
(2023)
The SARS-CoV-2 Alpha variant was associated with increased clinical severity of COVID-19 in Scotland: A genomics-based retrospective cohort analysis.
PLoS ONE
, 18
(4)
, Article e0284187. 10.1371/journal.pone.0284187.
|
|
|
Pascual, J;
Attard, G;
Bidard, FC;
Curigliano, G;
De Mattos-Arruda, L;
Diehn, M;
Italiano, A;
... Turner, NC; + view all
(2022)
ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group.
Annals of Oncology
, 33
(8)
pp. 750-768.
10.1016/j.annonc.2022.05.520.
|
|
|
Passaro, Antonio;
Al Bakir, Maise;
Hamilton, Emily G;
Diehn, Maximilian;
André, Fabrice;
Roy-Chowdhuri, Sinchita;
Mountzios, Giannis;
... Peters, Solange; + view all
(2024)
Cancer biomarkers: Emerging trends and clinical implications for personalized treatment.
Cell
, 187
(7)
pp. 1617-1635.
10.1016/j.cell.2024.02.041.
|
|
Patel, P;
Alrifai, D;
McDonald, F;
Forster, M;
(2020)
Beyond chemoradiotherapy: improving treatment outcomes for patients with stage III unresectable non-small-cell lung cancer through immuno-oncology and durvalumab (Imfinzi®▼, AstraZeneca UK Limited).
British Journal of Cancer
, 123
pp. 18-27.
10.1038/s41416-020-01071-5.
|
|
|
Patel, VB;
Zhabyeyev, P;
Chen, X;
Wang, F;
Paul, M;
Fan, D;
McLean, BA;
... Oudit, GY; + view all
(2018)
PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease.
Nature Communications
, 9
(1)
, Article 5390. 10.1038/s41467-018-07812-8.
|
|
|
Paul, DS;
Guilhamon, P;
Karpathakis, A;
Butcher, LM;
Thirlwell, C;
Feber, A;
Beck, S;
(2014)
Assessment of RainDrop BS-seq as a method for large-scale, targeted bisulfite sequencing.
Epigenetics
, 9
(5)
pp. 678-684.
10.4161/epi.28041.
|
|
|
Pawlik, Piotr;
(2025)
Inference of clone-specific copy numbers from bulk tumour DNA.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Pawsey, A;
Mahalingam, P;
Senthivel, N;
Ramessur, A;
Turnbull, E;
Usman, S;
Browne, R;
... Eminowicz, G; + view all
(2025)
Real World Outcomes in Patients With Recurrent, Advanced, or Metastatic Endometrial Cancer Treated With Lenvatinib Plus Pembrolizumab.
Clinical Oncology
, 37
, Article 103656. 10.1016/j.clon.2024.10.008.
|
|
Paz, K;
Flynn, R;
Du, J;
Tannheimer, S;
Johnson, AJ;
Dong, S;
Stark, A-K;
... Blazar, BR; + view all
(2019)
Targeting PI3Kδ function for amelioration of murine chronic graft‐versus‐host disease.
American Journal of Transplantation
, 19
(6)
pp. 1820-1830.
10.1111/ajt.15305.
|
|
Paz-Ares, L;
Forster, M;
Boni, V;
Szyldergemajn, S;
Corral, J;
Turnbull, S;
Cubillo, A;
... Calvo, E; + view all
(2017)
Phase I clinical and pharmacokinetic study of PM01183 (a tetrahydroisoquinoline, Lurbinectedin) in combination with gemcitabine in patients with advanced solid tumors.
Investigational New Drugs
, 35
(2)
pp. 198-206.
10.1007/s10637-016-0410-3.
|
|
Pearce, David;
(2021)
Investigation of fibulin-2 in pulmonary fibrosis.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
|
Pearce, David RR;
Akarca, Ayse UU;
De Maeyer, Roel PH;
Kostina, Emily;
Huebner, Ariana;
Sivakumar, Monica;
Karasaki, Takahiro;
... Hynds, Robert EE; + view all
(2023)
Phenotyping of lymphoproliferative tumours generated in xenografts of non-small cell lung cancer.
Frontiers in Oncology
, 13
, Article 1156743. 10.3389/fonc.2023.1156743.
|
|
Pearson, AD;
Gaspar, N;
Janeway, K;
Campbell-Hewson, Q;
Lawlor, ER;
Copland, C;
Karres, D;
... Vassal, G; + view all
(2022)
Paediatric Strategy Forum for medicinal product development of multi-targeted kinase inhibitors in bone sarcomas: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
European Journal of Cancer
, 173
pp. 71-90.
10.1016/j.ejca.2022.06.008.
|
|
Peipert, John Devin;
Goble, Sandra;
Isaacson, Jeff;
Tang, Xiaodan;
Wallace, Katrine;
Coleman, Robert L;
Ledermann, Jonathan A;
(2023)
Patient-reported outcomes of maintenance rucaparib in patients with recurrent ovarian carcinoma in ARIEL3, a phase III, randomized, placebo-controlled trial.
Gynecologic Oncology
, 175
pp. 1-7.
10.1016/j.ygyno.2023.05060.
|
|
Peix, L;
Evans, IC;
Pearce, DR;
Simpson, JK;
Maher, TM;
McAnulty, RJ;
(2018)
Diverse functions of clusterin promote and protect against the development of pulmonary fibrosis.
Scientific Reports
, 8
, Article 1906. 10.1038/s41598-018-20316-1.
|
|
Pemberton, L;
Ng, K;
McGovern, U;
Macdonald, A;
Barot, H;
Galazi, M;
Wilson, P;
... Shamash, J; + view all
(2021)
Febrile neutropenia (FN) rates in metastatic hormone sensitive prostate cancer: the role of antibiotics as primary prophylaxis.
Prostate Cancer and Prostatic Diseases
, 24
pp. 166-168.
10.1038/s41391-020-0261-z.
|
|
Peña, OA;
Lubin, A;
Hockings, C;
Rowell, J;
Jung, Y;
Hoade, Y;
Dace, P;
... Payne, EM; + view all
(2021)
TLR7 ligation augments hematopoiesis in Rps14 (uS11) deficiency via paradoxical suppression of inflammatory signaling.
Blood Advances
, 5
(20)
pp. 4112-4124.
10.1182/bloodadvances.2020003055.
|
|
|
Peneder, P;
Stutz, AM;
Surdez, D;
Krumbholz, M;
Semper, S;
Chicard, M;
Sheffield, NC;
... Tomazou, EM; + view all
(2021)
Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden.
Nature Communications
, 12
(1)
, Article 3230. 10.1038/s41467-021-23445-w.
|
|
|
Pennycuick, A;
Teixeira, VH;
AbdulJabbar, K;
Raza, SEA;
Lund, T;
Akarca, AU;
Rosenthal, R;
... Janes, SM; + view all
(2020)
Immune surveillance in clinical regression of pre-invasive squamous cell lung cancer.
Cancer Discovery
, 10
(10)
pp. 1489-1499.
10.1158/2159-8290.CD-19-1366.
|
|
Perez-Gracia, JL;
Awada, A;
Calvo, E;
Amaral, T;
Arkenau, H-T;
Gruenwald, V;
Bodoky, G;
... Douillard, J-Y; + view all
(2020)
ESMO Clinical Research Observatory (ECRO): improving the efficiency of clinical research through rationalisation of bureaucracy.
ESMO Open
, 5
(3)
, Article e000662. 10.1136/esmoopen-2019-000662.
|
|
|
Perna, C;
Eminowicz, G;
Asghar, U;
Imseeh, G;
Kirkwood, A;
Mitra, A;
Arora, R;
... McCormack, M; + view all
(2016)
Uterine carcinosarcoma: a retrospective clinical cohort analysis.
Presented at: ESMO 2016: 41st ESMO Congress, Copenhagen, Denmark.
|
|
Perry, N;
Moss, S;
Dixon, S;
Milner, S;
Mokbel, K;
Lemech, C;
Arkenau, H-T;
... Pinker, K; + view all
(2020)
Mammographic Breast Density and Urbanization: Interactions with BMI, Environmental, Lifestyle, and Other Patient Factors.
Diagnostics
, 10
(6)
, Article 418. 10.3390/diagnostics10060418.
|
|
|
Pett, L;
Kiakos, K;
Satam, V;
Patil, P;
Laughlin-Toth, S;
Gregory, M;
Bowerman, M;
... Hartley, JA; + view all
(2017)
Modulation of topoisomerase IIα expression and chemosensitivity through targeted inhibition of NF-Y:DNA binding by a diamino p-anisyl-benzimidazole (Hx) polyamide.
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
, 1860
(5)
pp. 617-629.
10.1016/j.bbagrm.2016.10.005.
|
|
Pettitt, SJ;
Frankum, JR;
Punta, M;
Lise, S;
Alexander, J;
Chen, Y;
Yap, TA;
... Lord, CJ; + view all
(2020)
Clinical brca1/2 reversion analysis identifies hotspot mutations and predicted neoantigens associated with therapy resistance.
Cancer Discovery
, 10
(10)
pp. 1475-1488.
10.1158/2159-8290.CD-19-1485.
|
|
Pich, Oriol;
Bailey, Chris;
Watkins, Thomas BK;
Zaccaria, Simone;
Jamal-Hanjani, Mariam;
Swanton, Charles;
(2022)
The translational challenges of precision oncology.
Cancer Cell
, 40
(5)
pp. 458-478.
10.1016/j.ccell.2022.04.002.
|
|
Pickles, OJ;
Lee, LYW;
Starkey, T;
Freeman-Mills, L;
Olsson-Brown, A;
Cheng, V;
Hughes, DJ;
... Middleton, G; + view all
(2020)
Immune checkpoint blockade: releasing the breaks or a protective barrier to COVID-19 severe acute respiratory syndrome?
British Journal of Cancer
, 123
pp. 691-693.
10.1038/s41416-020-0930-7.
|
|
Pinard, CJ;
Tran, WT;
Lagree, A;
Lu, FI;
Klein, J;
Oblak, ML;
Salgado, R;
... Moore, DA; + view all
(2022)
Comparative Evaluation of Tumor-Infiltrating Lymphocytes in Companion Animals: Immuno-Oncology as a Relevant Translational Model for Cancer Therapy.
Cancers
, 14
(20)
, Article 5008. 10.3390/cancers14205008.
|
|
Pinato, David J;
Ferrante, Daniela;
Aguilar-Company, Juan;
Bower, Mark;
Salazar, Ramon;
Mirallas, Oriol;
Sureda, Anna;
... Cortellini, Alessio; + view all
(2022)
Vaccination against SARS-CoV-2 protects from morbidity, mortality, and sequelae from COVID19 in patients with cancer.
European Journal of Cancer
, 171
pp. 64-74.
10.1016/j.ejca.2022.04.036.
|
|
Pinato, DJ;
Aguilar-Company, J;
Ferrante, D;
Hanbury, G;
Bower, M;
Salazar, R;
Mirallas, O;
... Chester, J; + view all
(2022)
Outcomes of the SARS-CoV-2 omicron (B.1.1.529) variant outbreak among vaccinated and unvaccinated patients with cancer in Europe: results from the retrospective, multicentre, OnCovid registry study.
The Lancet Oncology
, 23
(7)
pp. 865-875.
10.1016/S1470-2045(22)00273-X.
|
|
Pinato, DJ;
Scotti, L;
Gennari, A;
Colomba-Blameble, E;
Dolly, S;
Loizidou, A;
Chester, J;
... Cortellini, A; + view all
(2021)
Determinants of enhanced vulnerability to COVID-19 in UK cancer patients: a European Study.
European Journal of Cancer
, 150
pp. 190-202.
10.1016/j.ejca.2021.03.035.
|
|
Pinato, DJ;
Tabernero, J;
Bower, M;
Scotti, L;
Patel, M;
Colomba, E;
Dolly, S;
... Iglesias, M; + view all
(2021)
Prevalence and impact of COVID-19 sequelae on treatment and survival of patients with cancer who recovered from SARS-CoV-2 infection: evidence from the OnCovid retrospective, multicentre registry study.
The Lancet Oncology
10.1016/s1470-2045(21)00573-8.
(In press).
|
|
|
Pinato, DJ;
Lee, AJX;
Biello, F;
Seguí, E;
Aguilar-Company, J;
Carbó, A;
Bruna, R;
... Gennari, A; + view all
(2020)
Presenting Features and Early Mortality from SARS-CoV-2 Infection in Cancer Patients during the Initial Stage of the COVID-19 Pandemic in Europe.
Cancers
, 12
(7)
, Article 1841. 10.3390/cancers12071841.
|
|
|
Pinato, DJ;
Mauri, FA;
Spina, P;
Cain, O;
Siddique, A;
Goldin, R;
Victor, S;
... Sharma, R; + view all
(2019)
Clinical implications of heterogeneity in PD-L1 immunohistochemical detection in hepatocellular carcinoma: the Blueprint-HCC study.
British Journal of Cancer
, 120
(12)
pp. 1033-1036.
10.1038/s41416-019-0466-x.
|
|
|
Pinder, Christopher L;
Jankovic, Dylan;
Fox, Thomas A;
Kirkwood, Amy;
Enfield, Louise;
Alrubayyi, Aljawharah;
Touizer, Emma;
... Morris, Emma C; + view all
(2023)
Humoral and cellular responses to SARS-CoV-2 in patients with B-cell haematological malignancies improve with successive vaccination.
British Journal of Haematology
10.1111/bjh.18962.
(In press).
|
|
Pinder, SE;
Campbell, AF;
Bartlett, JMS;
Marshall, A;
Allen, D;
Falzon, M;
Dunn, JA;
... Stein, RC; + view all
(2017)
Discrepancies in central review re-testing of patients with ER-positive and HER2-negative breast cancer in the OPTIMA prelim randomised clinical trial.
British Journal of Cancer
, 116
(7)
pp. 859-863.
10.1038/bjc.2017.28.
|
|
Pinto, M;
(2002)
Induction and rejoining of DNA double-strand breaks in human cells after exposure to ionising radiation: an experimental and modelling approach.
Doctoral thesis , University of London.
|
|
Pipinikas, C;
Dibra, H;
Karpathakis, A;
Feber, A;
Novelli, M;
Oukrif, D;
Fusai, G;
... Thirlwell, C; + view all
(2015)
Epigenetic dysregulation and poorer prognosis in DAXX-deficient pancreatic neuroendocrine tumours.
[Letter].
Endocrine-Related Cancer
, 22
(3)
L13-L18.
10.1530/ERC-15-0108.
|
|
Pirrò, S;
Matic, I;
Colizzi, V;
Galgani, A;
(2021)
The microRNA analysis portal is a next-generation tool for exploring and analyzing miRNA-focused data in the literature.
Scientific Reports
, 11
, Article 9007. 10.1038/s41598-021-88617-6.
|
|
|
Plesner, T;
Arkenau, H-T;
Gimsing, P;
Krejcik, J;
Lemech, C;
Minnema, MC;
Lassen, U;
... Richardson, PG; + view all
(2016)
Phase 1/2 study of daratumumab, lenalidomide, and dexamethasone for relapsed multiple myeloma.
Blood
, 128
(14)
pp. 1821-1828.
10.1182/blood-2016-07-726729.
|
|
|
Plesner, T;
Arkenau, HT;
Gay, F;
Minnema, MC;
Boccadoro, M;
Moreau, P;
Cavenagh, J;
... Richardson, PG; + view all
(2019)
Enduring efficacy and tolerability of daratumumab in combination with lenalidomide and dexamethasone in patients with relapsed or relapsed/refractory multiple myeloma (GEN503): final results of an open-label, phase 1/2 study.
British Journal of Haematology
, 186
(3)
e35-e39.
10.1111/bjh.15879.
|
|
Plummer, R;
Dean, E;
Arkenau, HT;
Redfern, C;
Spira, AI;
Melear, JM;
Chung, KY;
... Shapiro, GI; + view all
(2022)
A phase 1b study evaluating the safety and preliminary efficacy of berzosertib in combination with gemcitabine in patients with advanced non-small cell lung cancer.
Lung Cancer
, 163
pp. 19-26.
10.1016/j.lungcan.2021.11.011.
|
|
|
Pocock, R;
Farah, N;
Richardson, SE;
Mansour, MR;
(2021)
Current and emerging therapeutic approaches for T-cell acute lymphoblastic leukaemia.
British Journal of Haematology
10.1111/bjh.17310.
(In press).
|
|
|
Posor, York;
Kampyli, Charis;
Bilanges, Benoit;
Ganguli, Sushila;
Koch, Philipp A;
Wallroth, Alexander;
Morelli, Daniele;
... Vanhaesebroeck, Bart; + view all
(2022)
Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover.
Developmental Cell
10.1016/j.devcel.2022.06.011.
|
|
Powles, T;
Kockx, M;
Rodriguez-Vida, A;
Duran, I;
Crabb, SJ;
Van Der Heijden, MS;
Szabados, B;
... Castellano, D; + view all
(2019)
Clinical efficacy and biomarker analysis of neoadjuvant atezolizumab in operable urothelial carcinoma in the ABACUS trial.
Nature Medicine
, 25
(11)
pp. 1706-1714.
10.1038/s41591-019-0628-7.
|
|
|
Powles, T;
O'Donnell, PH;
Massard, C;
Arkenau, H-T;
Friedlander, T;
Hoimes, CJ;
Lee, JL;
... Hahn, NM; + view all
(2017)
Efficacy and Safety of Durvalumab in Locally Advanced or Metastatic Urothelial Carcinoma. Updated Results From a Phase 1/2 Open-label Study.
JAMA Oncology
, 3
(9)
, Article e172411. 10.1001/jamaoncol.2017.2411.
|
|
Prêle, Cecilia M;
Miles, Tylah;
Pearce, David R;
O'Donoghue, Robert J;
Grainge, Chris;
Barrett, Lucy;
Birnie, Kimberly;
... Mutsaers, Steven E; + view all
(2022)
Plasma cell but not CD20-mediated B cell depletion protects from bleomycin-induced lung fibrosis.
European Respiratory Journal
, 60
(5)
, Article 2101469. 10.1183/13993003.01469-2021.
|
|
Prele, CM;
Iosifidis, T;
McAnulty, RJ;
Pearce, DR;
Badrian, B;
Miles, T;
Jamieson, SE;
... Mutsaers, SE; + view all
(2021)
Reduced SOCS1 Expression in Lung Fibroblasts from Patients with IPF Is Not Mediated by Promoter Methylation or Mir155.
Biomedicines
, 9
(5)
, Article 498. 10.3390/biomedicines9050498.
|
|
|
Prendergast, SC;
Strobl, A-C;
Cross, W;
Pillay, N;
Strauss, SJ;
Ye, H;
Lindsay, D;
... Amary, F; + view all
(2020)
Sarcoma and the 100,000 Genomes Project: our experience and changes to practice.
The Journal of Pathology: Clinical Research
10.1002/cjp2.174.
(In press).
|
|
|
Propper, David J;
Gao, Fangfei;
Saunders, Mark P;
Sarker, Debashis;
Hartley, John A;
Spanswick, Victoria J;
Lowe, Helen L;
... Hochhauser, Daniel; + view all
(2023)
PANTHER: AZD8931, inhibitor of EGFR, ERBB2 and ERBB3 signalling, combined with FOLFIRI: a Phase I/II study to determine the importance of schedule and activity in colorectal cancer.
British Journal of Cancer
, 128
(2)
pp. 245-254.
10.1038/s41416-022-02015-x.
|
|
Pruis, Melinda A;
Krebs, Matthew G;
Plummer, Ruth;
De Vos, Filip;
Angevin, Eric;
Prenen, Hans;
Forster, Martin D;
... Lolkema, Martijn P; + view all
(2023)
A Phase I Trial of the Dual MET Kinase/OCT-2 Inhibitor OMO-1 in Metastatic Solid Malignancies Including MET Exon 14 Mutated Lung Cancer.
The Oncologist
, Article oyad146. 10.1093/oncolo/oyad146.
(In press).
|
|
Przewrocka, J;
Rowan, A;
Rosenthal, R;
Kanu, N;
Swanton, C;
(2020)
Unintended on-target chromosomal instability following CRISPR/Cas9 single gene targeting.
Annals of Oncology
, 31
(9)
pp. 1270-1273.
10.1016/j.annonc.2020.04.480.
|
|
Puglisi, M;
Molife, LR;
de Jonge, MJ;
Khan, KH;
Doorn, LV;
Forster, MD;
Blanco, M;
... Eskens, FA; + view all
(2021)
A Phase I study of the safety, pharmacokinetics and efficacy of navitoclax plus docetaxel in patients with advanced solid tumors.
Future Oncology
10.2217/fon-2021-0140.
(In press).
|
|
|
Punjabi, A;
Barrett, E;
Cheng, A;
Mulla, A;
Walls, G;
Johnston, D;
McAleese, J;
... Evison, M; + view all
(2021)
Neutrophil-Lymphocyte Ratio and Absolute Lymphocyte Count as Prognostic Markers in Patients Treated with Curative-intent Radiotherapy for Non-small Cell Lung Cancer.
Clinical Oncology
, 33
(8)
e331-e338.
10.1016/j.clon.2021.03.019.
|
|
Purro, Silvia A;
Farmer, Michael;
Noble, Elizabeth;
Sarell, Claire J;
Powell, Megan;
Yip, Daniel;
Giggins, Lauren;
... Collinge, John; + view all
(2023)
Two mouse models of Alzheimer's disease accumulate amyloid at different rates and have distinct Aβ oligomer profiles unaltered by ablation of cellular prion protein.
PLoS One
, 18
(11)
, Article e0294465. 10.1371/journal.pone.0294465.
|
|
Puttick, Clare;
Jones, Thomas P;
Leung, Michelle M;
Galvez-Cancino, Felipe;
Liu, Jiali;
Varas-Godoy, Manuel;
Rowan, Andrew;
... Mcgranahan, Nicholas; + view all
(2024)
MHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolution.
Nature Genetics
, 56
(10)
pp. 2121-2131.
10.1038/s41588-024-01883-8.
|
|
|
PUVVADA, MS;
HARTLEY, JA;
JENKINS, TC;
THURSTON, DE;
(1993)
A quantitative assay to measure the relative dna-binding affinity of pyrrolo[2,1-c][1,4]benzodiazepine (pbd) antitumor antibiotics based on the inhibition of restriction-endonuclease bamhi.
Nucleic Acids Research
, 21
(16)
3671 - 3675.
10.1093/nar/21.16.3671.
|
|
|
Pye, H;
Singh, S;
Norris, JM;
Carmona Echeverria, LM;
Stavrinides, V;
Grey, A;
Dinneen, E;
... Whitaker, HC; + view all
(2021)
Evaluation of PSA and PSA Density in a Multiparametric Magnetic Resonance Imaging-Directed Diagnostic Pathway for Suspected Prostate Cancer: The INNOVATE Trial.
Cancers
, 13
(8)
, Article 1985. 10.3390/cancers13081985.
|
|
Q
|
Qayyum, MS;
Hayat, H;
Matharu, RK;
Tabish, TA;
Edirisinghe, M;
(2019)
Boron nitride nanoscrolls: Structure, synthesis, and applications.
Applied Physics Reviews
, 6
(2)
, Article 021310. 10.1063/1.5092547.
|
|
Qin, Shukui;
Kudo, Masatoshi;
Meyer, Tim;
Bai, Yuxian;
Guo, Yabing;
Meng, Zhiqiang;
Satoh, Taroh;
... Zhu, Andrew X; + view all
(2023)
Tislelizumab vs Sorafenib as First-Line Treatment for Unresectable Hepatocellular Carcinoma:
A Phase 3 Randomized Clinical Trial.
JAMA Oncology
10.1001/jamaoncol.2023.4003.
(In press).
|
|
|
Qin, X;
Tape, CJ;
(2020)
Deciphering Organoids: High-Dimensional Analysis of Biomimetic Cultures.
Trends in Biotechnology
, 39
(8)
pp. 774-787.
10.1016/j.tibtech.2020.10.013.
|
|
Qin, Xiao;
Cardoso Rodriguez, Ferran;
Sufi, Jahangir;
Vlckova, Petra;
Claus, Jeroen;
Tape, Christopher J;
(2023)
An oncogenic phenoscape of colonic stem cell polarization.
Cell
, 186
(25)
5554-5568.e18.
10.1016/j.cell.2023.11.004.
|
|
Qin, Xiao;
Sufi, Jahangir;
Vlckova, Petra;
Kyriakidou, Pelagia;
Acton, Sophie;
Li, Vivian;
Nitz, Mark;
(2019)
Single-Cell Signalling Analysis of Heterocellular Organoids.
BioRxiv: Cold Spring Harbor, NY, USA.
|
|
|
Qin, Xiao;
Tape, Christopher J;
(2024)
Functional analysis of cell plasticity using single-cell technologies.
Trends in Cell Biology
10.1016/j.tcb.2024.01.006.
(In press).
|
|
|
Qin, S;
Finn, RS;
Kudo, M;
Meyer, T;
Vogel, A;
Ducreux, M;
Macarulla, TM;
... Zhu, AX; + view all
(2019)
RATIONALE 301 study: tislelizumab versus sorafenib as first-line treatment for unresectable hepatocellular carcinoma.
Future Oncology
, 15
(16)
pp. 1811-1822.
10.2217/fon-2019-0097.
|
|
|
Qin, X;
Sufi, J;
Vlckova, P;
Kyriakidou, P;
Acton, SE;
Li, VSW;
Nitz, M;
(2020)
Cell-type-specific signaling networks in heterocellular organoids.
Nature Methods
, 17
pp. 335-342.
10.1038/s41592-020-0737-8.
|
R
|
Rabanal-Ruiz, Y;
Byron, A;
Wirth, A;
Madsen, R;
Sedlackova, L;
Hewitt, G;
Nelson, G;
... Korolchuk, VI; + view all
(2021)
mTORC1 activity is supported by spatial association with focal adhesions.
Journal of Cell Biology
, 220
(5)
, Article e202004010. 10.1083/jcb.202004010.
|
|
|
Rahman, B;
Lanceley, A;
Kristeleit, R;
Ledermann, J;
Lockley, M;
McCormack, M;
Mould, T;
(2019)
Mainstreamed genetic testing for women with ovarian cancer: first-year experience.
Journal of Medical Genetics
, 56
(3)
pp. 195-198.
10.1136/jmedgenet-2017-105140.
|
|
Rajan, Sanjana;
Zaccaria, Simone;
Cannon, Matthew V;
Cam, Maren;
Gross, Amy C;
Raphael, Benjamin J;
Roberts, Ryan D;
(2023)
Structurally Complex Osteosarcoma Genomes Exhibit Limited Heterogeneity within Individual Tumors and across Evolutionary Time.
Cancer Research Communications
, 3
(4)
pp. 564-575.
10.1158/2767-9764.CRC-22-0348.
|
|
Ramage, JK;
Punia, P;
Faluyi, O;
Frilling, A;
Meyer, T;
Saharan, R;
Valle, JW;
(2019)
Observational Study to Assess Quality of Life in Patients with Pancreatic Neuroendocrine Tumors Receiving Treatment with Everolimus: The OBLIQUE Study (UK Phase IV Trial).
Neuroendocrinology
, 108
(4)
pp. 317-327.
10.1159/000497330.
|
|
Ramos Zapatero, María;
Tong, Alexander;
Opzoomer, James W;
O’Sullivan, Rhianna;
Cardoso Rodriguez, Ferran;
Sufi, Jahangir;
Vlckova, Petra;
... Tape, Christopher J; + view all
(2023)
Trellis tree-based analysis reveals stromal regulation of patient-derived organoid drug responses.
Cell
, 186
(25)
5606-5619.e24.
10.1016/j.cell.2023.11.005.
|
|
Rane, Jayant;
Harsanyi, Csilla;
Grimes, Helen;
Moinuddin, Syed;
Quingua, Kristina;
Petkar, Shabnam;
Dubash, Suraiya;
... Wilson, James; + view all
(2022)
Tumour location is important in selecting patients who may benefit from abdominal compression when receiving SABR for lung tumours.
Presented at: 20th Annual British Thoracic Oncology Group Conference 2022, Virtual conference.
|
|
|
Rane, Jayant K;
Chowdhury, Amani;
Kinnaird, William;
Marks, Gillian;
Davda, Reena;
(2021)
Treatment of metastatic hormone‐sensitive prostate cancer.
Trends in Urology & Men's Health
, 12
(6)
pp. 7-10.
10.1002/tre.824.
|
|
|
Rane, Jayant K;
Frankell, Alexander M;
Weeden, Clare E;
Swanton, Charles;
(2023)
Clonal Evolution in Healthy and Premalignant Tissues: Implications for Early Cancer Interception Strategies.
Cancer Prevention Research
, 16
(7)
pp. 369-378.
10.1158/1940-6207.CAPR-22-0469.
|
|
Rauf, A;
Razzaq, S;
Tabish, TA;
Tahseen, S;
Sandhu, MA;
Shahnaz, G;
(2021)
Investigating the intracellular bactericidal effects of rifampicin loaded S-protected thiomeric chitosan nanocargoes against Mycobacterium tuberculosis.
Journal of Drug Delivery Science and Technology
, 61
, Article 102184. 10.1016/j.jddst.2020.102184.
|
|
Raza, SEA;
AbdulJabbar, K;
Jamal-Hanjani, M;
Veeriah, S;
Le Quesne, J;
Swanton, C;
Yuan, Y;
(2019)
Deconvolving Convolutional Neural Network for Cell Detection.
In:
2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019).
(pp. pp. 891-894).
IEEE: Venice, Italy,.
|
|
|
Reading, James L;
Caswell, Deborah R;
Swanton, Charles;
(2023)
Tumor heterogeneity impairs immunogenicity in mismatch repair deficient tumors.
Nature Genetics
, 55
(10)
pp. 1610-1612.
10.1038/s41588-023-01492-x.
|
|
Reading, JL;
Gálvez-Cancino, F;
Swanton, RC;
Lladser, A;
Peggs, K;
Quezada, S;
(2018)
The function and dysfunction of memory CD8+ T cells in tumor immunity.
Immunological Reviews
, 283
(1)
pp. 194-212.
10.1111/imr.12657.
|
|
Reale, ML;
Bironzo, P;
Bertaglia, V;
Palesandro, E;
Leone, G;
Tabbò, F;
Bungaro, M;
... Novello, S; + view all
(2020)
SARS-CoV-2 Infection in Cancer Patients: A Picture of an Italian Onco-Covid Unit.
Frontiers in Oncology
, 10
, Article 1722. 10.3389/fonc.2020.01722.
|
|
Reichold, M;
Klootwijk, ED;
Reinders, J;
Otto, EA;
Milani, M;
Broeker, C;
Laing, C;
... Kleta, R; + view all
(2018)
Glycine Amidinotransferase (GATM), Renal Fanconi Syndrome, and Kidney Failure.
Journal of the American Society of Nephrology
, 29
(7)
pp. 1849-1858.
10.1681/ASN.2017111179.
|
|
|
Ren, Zhenggang;
Ducreux, Michel;
Abou-Alfa, Ghassan K;
Merle, Philippe;
Fang, Weijia;
Edeline, Julien;
Li, Zhiwei;
... Cheng, Ann-Lii; + view all
(2022)
Tislelizumab in Patients with Previously Treated Advanced Hepatocellular Carcinoma (RATIONALE-208): A Multicenter, Non-Randomized, Open-Label, Phase 2 Trial.
Liver Cancer
10.1159/000527175.
(In press).
|
|
Richardson, S;
Brian, D;
Grandage, V;
Hough, R;
Kottaridis, P;
Mansour, M;
Payne, EMC;
(2019)
Intensive Chemotherapy Is Associated With Poor Overall Survival in Autoimmune Disease-associated Myeloid Malignancies.
HemaSphere
, 3
(1)
, Article e164. 10.1097/HS9.0000000000000164.
|
|
|
Richardson, SE;
(2016)
Modeling TEL-AML1 childhood acute lymphoblastic leukaemia using human pluripotent stem cells.
Doctoral thesis , UCL (University College London).
|
|
Richardson, SE;
Ghazanfari, R;
Chhetri, J;
Enver, T;
Böiers, C;
(2021)
In vitro differentiation of human pluripotent stem cells into the B lineage using OP9-MS5 co-culture.
STAR Protocols
, 2
(2)
, Article 100420. 10.1016/j.xpro.2021.100420.
|
|
|
Rimassa, Lorenza;
Kelley, Robin Kate;
Meyer, Tim;
Ryoo, Baek-Yeol;
Merle, Philippe;
Park, Joong-Won;
Blanc, Jean-Frederic;
... Abou-Alfa, Ghassan K; + view all
(2021)
Outcomes Based on Plasma Biomarkers for the Phase 3 CELESTIAL Trial of Cabozantinib versus Placebo in Advanced Hepatocellular Carcinoma.
Liver Cancer
, 11
(1)
pp. 38-47.
10.1159/000519867.
|
|
|
Riquelme, JA;
Westermeier, F;
Hall, AR;
Vicencio, JM;
Pedrozo, Z;
Ibacache, M;
Fuenzalida, B;
... Lavandero, S; + view all
(2016)
Dexmedetomidine protects the heart against ischemia-reperfusion injury by an endothelial eNOS/NO dependent mechanism.
Pharmacological Research
, 103
pp. 318-327.
10.1016/j.phrs.2015.11.004.
|
|
Rizzo, FM;
Meyer, T;
(2018)
Liquid Biopsies for Neuroendocrine Tumors: Circulating Tumor Cells, DNA, and MicroRNAs.
Endocrinology and Metabolism Clinics of North America
, 47
(3)
pp. 471-483.
10.1016/j.ecl.2018.04.002.
|
|
Rizzo, FM;
Vesely, C;
Childs, A;
Marafioti, T;
Khan, MS;
Mandair, D;
Cives, M;
... Meyer, T; + view all
(2019)
Circulating tumour cells and their association with bone metastases in patients with neuroendocrine tumours.
British Journal of Cancer
, 120
(3)
pp. 294-300.
10.1038/s41416-018-0367-4.
|
|
Robbe, Pauline;
Ridout, Kate E;
Vavoulis, Dimitrios V;
Dréau, Helene;
Kinnersley, Ben;
Denny, Nicholas;
Chubb, Daniel;
... Schuh, Anna; + view all
(2022)
Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features.
Nature Genetics
, 54
pp. 1675-1689.
10.1038/s41588-022-01211-y.
|
|
Robillard, L;
Nguyen, M;
Loehr, A;
Orsulic, S;
Kristeleit, RS;
Lin, K;
Raponi, M;
... Simmons, AD; + view all
(2017)
Preclinical evaluation of the PARP inhibitor rucaparib in combination with PD-1 and PD-L1 inhibition in a syngeneic BRCA1 mutant ovarian cancer model.
Presented at: AACR Annual Meeting 2017, Washington, D.C., USA.
|
|
|
Robinson, W;
Stone, JK;
Schischlik, F;
Gasmi, B;
Kelly, MC;
Seibert, C;
Dadkhah, K;
... Ruppin, E; + view all
(2024)
Identification of intracellular bacteria from multiple single-cell RNA-seq platforms using CSI-Microbes.
Science advances
, 10
(27)
, Article eadj7402. 10.1126/sciadv.adj7402.
|
|
Roddie, C;
Dias, J;
O'Reilly, MA;
Abbasian, M;
Cadinanos-Garai, A;
Vispute, K;
Bosshard-Carter, L;
... Peggs, KS; + view all
(2021)
Durable Responses and Low Toxicity After Fast Off-Rate CD19 Chimeric Antigen Receptor-T Therapy in Adults With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia.
Journal of Clinical Oncology
10.1200/jco.21.00917.
(In press).
|
|
|
Roddy, H;
Meyer, T;
Roddie, C;
(2022)
Novel Cellular Therapies for Hepatocellular Carcinoma.
Cancers
, 14
(3)
, Article 504. 10.3390/cancers14030504.
|
|
|
Rodríguez-Galán, O;
García-Gómez, JJ;
Rosado, IV;
Wei, W;
Méndez-Godoy, A;
Pillet, B;
Alekseenko, A;
... de la Cruz, J; + view all
(2020)
A functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae.
Nucleic Acids Research
10.1093/nar/gkaa1200.
(In press).
|
|
|
Rodríguez-Martínez, M;
Boissiére, T;
Gonzalez, MN;
Litchfield, K;
Mitter, R;
Walker, J;
Kjœr, S;
... Svejstrup, JQ; + view all
(2020)
Evidence That STK19 Is Not an NRAS-dependent Melanoma Driver.
Cell
, 181
(6)
1395-1405.e11.
10.1016/j.cell.2020.04.014.
|
|
|
Romero-Laorden, N;
Lozano, R;
Jayaram, A;
López-Campos, F;
Saez, MI;
Montesa, A;
Gutierrez-Pecharoman, A;
... Olmos, D; + view all
(2018)
Phase II pilot study of the prednisone to dexamethasone switch in metastatic castration-resistant prostate cancer (mCRPC) patients with limited progression on abiraterone plus prednisone (SWITCH study).
British Journal of Cancer
, 119
(9)
pp. 1052-1059.
10.1038/s41416-018-0123-9.
|
|
|
Roncolato, Felicia;
King, Madeleine T;
O'Connell, Rachel L;
Lee, Yeh Chen;
Joly, Florence;
Hilpert, Felix;
Lanceley, Anne;
... Friedlander, Michael; + view all
(2024)
Hidden in plain sight - Survival consequences of baseline symptom burden in women with recurrent ovarian cancer.
Gynecologic Oncology
, 185
pp. 128-137.
10.1016/j.ygyno.2024.02.025.
|
|
Rooshenas, L;
Elliott, D;
Wade, J;
Jepson, M;
Paramasivan, S;
Strong, S;
Wilson, C;
... POUT study group; + view all
(2016)
Conveying Equipoise during Recruitment for Clinical Trials: Qualitative Synthesis of Clinicians' Practices across Six Randomised Controlled Trials.
PLoS Med
, 13
(10)
, Article e1002147. 10.1371/journal.pmed.1002147.
|
|
|
Rooshenas, L;
Scott, LJ;
Blazeby, JM;
Rogers, CA;
Tilling, KM;
Husbands, S;
Conefrey, C;
... Wheatley, T; + view all
(2019)
The QuinteT Recruitment Intervention supported five randomized trials to recruit to target: a mixed-methods evaluation.
Journal of Clinical Epidemiology
, 106
pp. 108-120.
10.1016/j.jclinepi.2018.10.004.
|
|
Rosenthal, R;
Cadieux, EL;
Salgado, R;
Bakir, MA;
Moore, DA;
Hiley, CT;
Lund, T;
... TRACERx consortium; + view all
(2019)
Neoantigen-directed immune escape in lung cancer evolution.
Nature
10.1038/s41586-019-1032-7.
(In press).
|
|
Rosenthal, R;
McGranahan, N;
Herrero, J;
Swanton, C;
(2017)
Deciphering Genetic Intratumor Heterogeneity and Its Impact on Cancer Evolution.
Annual Review of Cancer Biology
, 1
pp. 223-240.
10.1146/annurev-cancerbio-042516-011348.
|
|
Rosenthal, R;
McGranahan, N;
Herrero, J;
Taylor, BS;
Swanton, C;
(2016)
deconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution.
Genome Biol
, 17
(1)
p. 31.
10.1186/s13059-016-0893-4.
|
|
Rosenthal, R;
Swanton, C;
McGranahan, N;
(2021)
Understanding the impact of immune-mediated selection on lung cancer evolution.
British Journal of Cancer
, 124
(10)
pp. 1615-1617.
10.1038/s41416-020-01232-6.
|
|
Rossello, X;
Riquelme, JA;
He, Z;
Taferner, S;
Vanhaesebroeck, B;
Davidson, SM;
Yellon, DM;
(2017)
The role of PI3Kα isoform in cardioprotection.
Basic Research in Cardiology
, 112
, Article 66. 10.1007/s00395-017-0657-7.
|
|
|
Rothermundt, C;
Seddon, BM;
Dileo, P;
Strauss, SJ;
Coleman, J;
Briggs, TW;
Haile, SR;
(2016)
Follow-up practices for high-grade extremity Osteosarcoma.
BMC Cancer
, 16
, Article 301. 10.1186/s12885-016-2333-y.
|
|
|
Rothermundt, C;
Whelan, JS;
Dileo, P;
Strauss, SJ;
Coleman, J;
Briggs, TW;
Haile, SR;
(2014)
What is the role of routine follow-up for localised limb soft tissue sarcomas? A retrospective analysis of 174 patients.
British Journal of Cancer
, 110
(10)
pp. 2420-2426.
10.1038/bjc.2014.200.
|
|
|
Round, T;
L'Esperance, V;
Bayly, J;
Brain, K;
Dallas, L;
Edwards, JG;
Haswell, T;
... Navani, N; + view all
(2021)
COVID-19 and the multidisciplinary care of patients with lung cancer: an evidence-based review and commentary.
British Journal of Cancer
, 125
pp. 629-640.
10.1038/s41416-021-01361-6.
|
|
Rowley, MI;
Coolen, ACC;
Vojnovic, B;
Barber, PR;
(2016)
Correction: Robust Bayesian fluorescence lifetime estimation, decay model selection and instrument response determination for low-intensity FLIM imaging.
PLoS ONE
, 11
(8)
, Article e0162224. 10.1371/journal.pone.0162224.
|
|
|
Rowley, MI;
Coolen, ACC;
Vojnovic, B;
Barber, PR;
(2016)
Robust Bayesian Fluorescence Lifetime Estimation, Decay Model Selection and Instrument Response Determination for Low-Intensity FLIM Imaging.
PLoS One
, 11
(6)
, Article e0158404. 10.1371/journal.pone.0158404.
|
|
|
Rush, HL;
Murphy, L;
Morgans, AK;
Clarke, NW;
Cook, AD;
Attard, G;
Macnair, A;
... Langley, RE; + view all
(2021)
Quality of Life in Men With Prostate Cancer Randomly Allocated to Receive Docetaxel or Abiraterone in the STAMPEDE Trial.
Journal of Clinical Oncology
10.1200/JCO.21.00728.
(In press).
|
|
S
|
Sacher, Adrian;
LoRusso, Patricia;
Patel, Manish R;
Miller, Wilson H;
Garralda, Elena;
Forster, Martin D;
Santoro, Armando;
... GO42144 Investigator and Study Group; + view all
(2023)
Single-Agent Divarasib (GDC-6036) in Solid Tumors with a KRAS G12C Mutation.
New England Journal of Medicine
, 389
(8)
pp. 710-721.
10.1056/NEJMoa2303810.
|
|
Sadeqi Azer, E;
Rashidi Mehrabadi, F;
Malikić, S;
Li, XC;
Bartok, O;
Litchfield, K;
Levy, R;
... Sahinalp, SC; + view all
(2020)
PhISCS-BnB: a fast branch and bound algorithm for the perfect tumor phylogeny reconstruction problem.
Bioinformatics
, 36
(S1)
i169-i176.
10.1093/bioinformatics/btaa464.
|
|
Sage, E;
Davies, A;
Kolluri, K;
Patrick, S;
Weil, B;
Rego, RVTP;
Edwards, A;
... Janes, SM; + view all
(2018)
Targeted stem cells expressing TRAIL as a therapy for lung Cancer TACTICAL: a phase I/II trial.
Lung Cancer
, 115
(Supp. 1)
S87-S87.
10.1016/S0169-5002(18)30222-8.
|
|
Saifuddin, A;
Baig, MS;
Dalal, P;
Strauss, SJ;
(2021)
The diagnosis of pulmonary metastases on chest computed tomography in primary bone sarcoma and musculoskeletal soft tissue sarcoma.
British Journal of Radiology
, 94
(1123)
, Article 20210088. 10.1259/bjr.20210088.
|
|
Salazar, R;
Garcia-Carbonero, R;
Libutti, SK;
Hendifar, AE;
Custodio, A;
Guimbaud, R;
Lombard-Bohas, C;
... Yao, JC; + view all
(2018)
Phase II Study of BEZ235 versus Everolimus in Patients with Mammalian Target of Rapamycin Inhibitor‐Naïve Advanced Pancreatic Neuroendocrine Tumors.
The Oncologist
, 23
(7)
766-e90.
10.1634/theoncologist.2017-0144.
|
|
Salvi, S;
Casadio, V;
Conteduca, V;
Lolli, C;
Gurioli, G;
Martignano, F;
Schepisi, G;
... De Giorgi, U; + view all
(2016)
Circulating AR copy number and outcome to enzalutamide in docetaxel-treated metastatic castration-resistant prostate cancer.
Oncotarget
, 7
(25)
pp. 37839-37845.
10.18632/oncotarget.9341.
|
|
|
Sangro, B;
Chan, SL;
Meyer, T;
Reig, M;
El-Khoueiry, A;
Galle, PR;
(2020)
Diagnosis and management of toxicities of immune checkpoint inhibitors in hepatocellular carcinoma.
Journal of Hepatology
, 72
(2)
pp. 320-341.
10.1016/j.jhep.2019.10.021.
|
|
Sansregret, L;
Patterson, JO;
Dewhurst, S;
Lopez-Garcia, C;
Koch, A;
McGranahan, N;
Chao, WCH;
... Swanton, C; + view all
(2017)
APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability.
Cancer Discovery
, 7
(2)
pp. 218-233.
10.1158/2159-8290.CD-16-0645.
|
|
Sansregret, L;
Swanton, C;
(2017)
The Role of Aneuploidy in Cancer Evolution.
Cold Spring Harbor Perspectives in Medicine
, 7
(1)
, Article a028373. 10.1101/cshperspect.a028373.
|
|
|
Sansregret, L;
Vanhaesebroeck, B;
Swanton, C;
(2018)
Determinants and clinical implications of chromosomal instability in cancer.
Nature Reviews Clinical Oncology
, 15
(3)
pp. 139-150.
10.1038/nrclinonc.2017.198.
|
|
Sarker, D;
Plummer, R;
Meyer, T;
Sodergren, M;
Basu, B;
Chee, CE;
Huang, K-W;
... Habib, N; + view all
(2020)
MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial.
Clinical Cancer Research
, 26
(15)
pp. 3936-3946.
10.1158/1078-0432.CCR-20-0414.
|
|
Sashittal, P;
Zaccaria, S;
El-Kebir, M;
(2021)
Parsimonious clone tree reconciliation in cancer.
In:
21st International Workshop on Algorithms in Bioinformatics (WABI 2021).
(pp. 9:1-9:21).
Schloss Dagstuhl -- Leibniz-Zentrum für Informatik: Dagstuhl, Germany.
|
|
|
Sashittal, Palash;
Zaccaria, Simone;
El-Kebir, Mohammed;
(2022)
Parsimonious Clone Tree Integration in cancer.
Algorithms for Molecular Biology
, 17
(1)
, Article 3. 10.1186/s13015-022-00209-9.
|
|
Sasieni, P;
Smittenaar, R;
Hubbell, E;
Broggio, J;
Neal, RD;
Swanton, C;
(2023)
Modelled mortality benefits of multi-cancer early detection screening in England.
British Journal of Cancer
, 129
pp. 72-80.
10.1038/s41416-023-02243-9.
|
|
Sasieni, P;
Swanton, C;
Neal, R;
(2025)
Advanced cancer: a robust surrogate of cancer mortality in early detection trials?
Annals of Oncology
10.1016/j.annonc.2025.03.001.
(In press).
|
|
Satas, G;
Zaccaria, S;
El-Kebir, M;
Raphael, BJ;
(2021)
DeCiFering the elusive cancer cell fraction in tumor heterogeneity and evolution.
Cell Systems
, 12
(10)
1004-1018.e10.
10.1016/j.cels.2021.07.006.
|
|
Satish, P;
Freeman, A;
Kelly, D;
Kirkham, A;
Orczyk, C;
Simpson, BS;
Giganti, F;
... Norris, JM; + view all
(2022)
Relationship of prostate cancer topography and tumour conspicuity on multiparametric magnetic resonance imaging: a protocol for a systematic review and meta-analysis.
BMJ Open
, 12
(1)
, Article e050376. 10.1136/bmjopen-2021-050376.
|
|
|
Satish, P;
Simpson, B;
Freeman, A;
Giganti, F;
Kirkham, A;
Orczyk, C;
Whitaker, H;
... Norris, JM; + view all
(2021)
Mapping Contemporary Biopsy Zones to Traditional Prostatic Anatomy: The Key to Understanding Relationships Between Prostate Cancer Topography, Magnetic Resonance Imaging Conspicuity, and Clinical Risk.
European Urology
, 80
(2)
pp. 263-265.
10.1016/j.eururo.2021.05.017.
|
|
Savas, Peter;
Teo, Zhi Ling;
Lefevre, Christophe;
Flensburg, Christoffer;
Caramia, Franco;
Alsop, Kathryn;
Mansour, Mariam;
... Loi, Sherene; + view all
(2017)
Correction: The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE".
[Corrigendum].
PLoS Med
, 14
(4)
e1002302.
10.1371/journal.pmed.1002302.
|
|
|
Savas, P;
Teo, ZL;
Lefevre, C;
Flensburg, C;
Caramia, F;
Alsop, K;
Mansour, M;
... Loi, S; + view all
(2016)
The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE".
PLoS Medicine
, 13
(12)
, Article e1002204. 10.1371/journal.pmed.1002204.
|
|
|
Scalera, Stefano;
Ricciuti, Biagio;
Marinelli, Daniele;
Mazzotta, Marco;
Cipriani, Laura;
Bon, Giulia;
Schiavoni, Giulia;
... Maugeri-Saccà, Marcello; + view all
(2024)
Transcriptional phenocopies of deleterious KEAP1 mutations correlate with survival outcomes in lung cancer treated with immunotherapy.
Clinical Cancer Research
10.1158/1078-0432.CCR-24-0626.
(In press).
|
|
Scelo, G;
Hofmann, JN;
Banks, RE;
Bigot, P;
Bhatt, RS;
Cancel-Tassin, G;
Chew, SK;
... Chanock, SJ; + view all
(2016)
International cancer seminars: a focus on kidney cancer.
Annals of Oncology
, 27
(8)
pp. 1382-1385.
10.1093/annonc/mdw186.
|
|
|
Scheipl, S;
Barnard, M;
Cottone, L;
Jorgensen, M;
Drewry, DH;
Zuercher, WJ;
Turlais, F;
... Flanagan, AM; + view all
(2016)
EGFR inhibitors identified as a potential treatment for chordoma in a focused compound screen.
J Pathol
, 239
(3)
pp. 320-334.
10.1002/path.4729.
|
|
|
Schenk, A;
López, S;
Kschischo, M;
McGranahan, N;
(2020)
Germline ancestry influences the evolutionary disease course in lung adenocarcinomas.
Evolutionary Applications
10.1111/eva.12964.
|
|
|
Scher, HI;
Graf, RP;
Schreiber, NA;
Jayaram, A;
Winquist, E;
McLaughlin, B;
Lu, D;
... Heller, G; + view all
(2018)
Assessment of the Validity of Nuclear-Localized Androgen Receptor Splice Variant 7 in Circulating Tumor Cells as a Predictive Biomarker for Castration-Resistant Prostate Cancer.
JAMA Oncology
, 4
(9)
pp. 1179-1186.
10.1001/jamaoncol.2018.1621.
|
|
Schiavone, F;
Bathia, R;
Letchmanan, K;
Masters, L;
Amos, C;
Bara, A;
Brown, L;
... Sydes, MR; + view all
(2019)
This is a platform alteration: a trial management perspective on the operational aspects of adaptive and platform and umbrella protocols.
Trials
, 20
, Article 264. 10.1186/s13063-019-3216-8.
|
|
Schmid, P;
Abraham, J;
Chan, S;
Wheatley, D;
Brunt, AM;
Nemsadze, G;
Baird, RD;
... Turner, NC; + view all
(2020)
Capivasertib Plus Paclitaxel Versus Placebo Plus Paclitaxel As First-Line Therapy for Metastatic Triple-Negative Breast Cancer: The PAKT Trial.
Journal of Clinical Oncology
, 38
(5)
pp. 423-433.
10.1200/JCO.19.00368.
|
|
Schmidt, NM;
Wing, PAC;
Diniz, MO;
Pallett, LJ;
Swadling, L;
Harris, JM;
Burton, AR;
... Maini, MK; + view all
(2021)
Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint.
Nature Communications
, 12
, Article 2814. 10.1038/s41467-021-22967-7.
|
|
|
Schöffski, P;
Kubickova, M;
Wozniak, A;
Blay, JY;
Strauss, SJ;
Stacchiotti, S;
Switaj, T;
... Kasper, B; + view all
(2021)
Long-term efficacy update of crizotinib in patients with advanced, inoperable inflammatory myofibroblastic tumour from EORTC trial 90101 CREATE.
European Journal of Cancer
, 156
pp. 12-23.
10.1016/j.ejca.2021.07.016.
|
|
|
Schöffski, P;
Sufliarsky, J;
Gelderblom, H;
Blay, J-Y;
Strauss, SJ;
Stacchiotti, S;
Rutkowski, P;
... Wozniak, A; + view all
(2018)
Crizotinib in patients with advanced, inoperable inflammatory myofibroblastic tumours with and without anaplastic lymphoma kinase gene alterations (European Organisation for Research and Treatment of Cancer 90101 CREATE): a multicentre, single-drug, prospective, non-randomised phase 2 trial.
Lancet Respir Med
, 6
(6)
pp. 431-441.
10.1016/S2213-2600(18)30116-4.
|
|
|
Schöffski, P;
Wozniak, A;
Casali, PG;
Rutkowski, P;
Blay, J-Y;
Lindner, LH;
Strauss, SJ;
... Bauer, S; + view all
(2017)
Activity and safety of crizotinib in patients with advanced clear cell sarcoma with MET alterations. European Organization for Research and Treatment of Cancer phase 2 trial 90101 "CREATE".
Annals of Oncology
, 28
(12)
pp. 3000-3008.
10.1093/annonc/mdx527.
|
|
Schöffski, P;
Wozniak, A;
Kasper, B;
Aamdal, S;
Leahy, MG;
Rutkowski, P;
Bauer, S;
... Stacchiotti, S; + view all
(2018)
Activity and safety of crizotinib in patients with alveolar soft part sarcoma with rearrangement of TFE3: European Organization for Research and Treatment of Cancer (EORTC) phase II trial 90101 'CREATE'.
Annals of Oncology
, 29
(3)
pp. 758-765.
10.1093/annonc/mdx774.
|
|
Schöffski, P;
Wozniak, A;
Leahy, MG;
Aamdal, S;
Rutkowski, P;
Bauer, S;
Richter, S;
... Strauss, SJ; + view all
(2018)
The tyrosine kinase inhibitor crizotinib does not have clinically meaningful activity in heavily pre-treated patients with advanced alveolar rhabdomyosarcoma with FOXO rearrangement: European Organisation for Research and Treatment of Cancer phase 2 trial 90101 'CREATE'.
European Journal of Cancer
, 94
pp. 156-167.
10.1016/j.ejca.2018.02.011.
|
|
Schöneberg, J;
Lehmann, M;
Ullrich, A;
Posor, Y;
Lo, W-T;
Lichtner, G;
Schmoranzer, J;
... Noé, F; + view all
(2017)
Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission.
Nature Communications
, 8
, Article 15873. 10.1038/ncomms15873.
|
|
Schumacher, FF;
Nunes, JP;
Maruani, A;
Chudasama, V;
Smith, ME;
Chester, KA;
Baker, JR;
(2014)
Next generation maleimides enable the controlled assembly of antibody-drug conjugates via native disulfide bond bridging.
Organic & Biomolecular Chemistry
, 12
(37)
pp. 7261-7269.
10.1039/c4ob01550a.
|
|
Schumacher, FF;
Sanchania, VA;
Tolner, B;
Wright, ZV;
Ryan, CP;
Smith, ME;
Ward, JM;
... Baker, JR; + view all
(2013)
Homogeneous antibody fragment conjugation by disulfide bridging introduces 'spinostics'.
[Magazine_article].
Scientific Reports
, 3
, Article 1525. 10.1038/srep01525.
|
|
|
Seddon, B;
Strauss, SJ;
Whelan, J;
Leahy, M;
Woll, PJ;
Cowie, F;
Rothermundt, C;
... Beare, S; + view all
(2017)
Gemcitabine and docetaxel versus doxorubicin as first-line treatment in previously untreated advanced unresectable or metastatic soft-tissue sarcomas (GeDDiS): a randomised controlled phase 3 trial.
The Lancet Oncology
, 18
(10)
pp. 1397-1410.
10.1016/S1470-2045(17)30622-8.
|
|
Seifert, W;
Posor, Y;
Schu, P;
Stenbeck, G;
Mundlos, S;
Klaassen, S;
Nuernberg, P;
... Kuehnisch, J; + view all
(2016)
The progressive ankylosis protein ANK facilitates clathrin- and adaptor-mediated membrane traffic at the trans-Golgi network-to-endosome interface.
Human Molecular Genetics
, 25
(17)
pp. 3836-3848.
10.1093/hmg/ddw230.
|
|
|
Semple, RK;
Vanhaesebroeck, B;
(2018)
Cancer drug tackles overgrowth syndrome.
Nature
, 558
(7711)
pp. 522-525.
|
|
Sena Teixeira Mendes, Larissa;
(2024)
Proliferation, inflammation and morphological features of hormone sensitive clinically advanced prostate cancer.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Sengerová, B;
Allerston, CK;
Abu, M;
Lee, SY;
Hartley, J;
Kiakos, K;
Schofield, CJ;
... McHugh, PJ; + view all
(2012)
Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleases.
Journal of Biological Chemistry
, 287
(31)
26254 -26267.
10.1074/jbc.M112.367243.
|
|
|
Sereno, M;
He, Z;
Smith, CR;
Baena, J;
Das, M;
Hastings, RK;
Rake, G;
... Le Quesne, J; + view all
(2021)
Inclusion of multiple high‐risk histopathological criteria improves the prediction of adjuvant chemotherapy efficacy in lung adenocarcinoma.
Histopathology
10.1111/his.14301.
(In press).
|
|
|
Sessa, C;
Balmaña, J;
Bober, SL;
Cardoso, MJ;
Colombo, N;
Curigliano, G;
Domchek, SM;
... ESMO, Guidelines Committee; + view all
(2023)
Risk reduction and screening of cancer in hereditary breast-ovarian cancer syndromes: ESMO Clinical Practice Guideline.
Annals of Oncology
, 34
(1)
pp. 33-47.
10.1016/j.annonc.2022.10.004.
|
|
Shah, Manish A;
Kojima, Takashi;
Hochhauser, Daniel;
Enzinger, Peter;
Raimbourg, Judith;
Hollebecque, Antoine;
Lordick, Florian;
... Kato, Ken; + view all
(2022)
T cell-inflamed gene expression profile and PD-L1 expression and pembrolizumab efficacy in advanced esophageal cancer.
Future Oncology
, 18
(25)
pp. 2783-2790.
10.2217/fon-2021-1134.
|
|
Shah, MA;
Kojima, T;
Hochhauser, D;
Enzinger, P;
Raimbourg, J;
Hollebecque, A;
Lordick, F;
... Kato, K; + view all
(2019)
Efficacy and Safety of Pembrolizumab for Heavily Pretreated Patients With Advanced, Metastatic Adenocarcinoma or Squamous Cell Carcinoma of the Esophagus. The Phase 2 KEYNOTE-180 Study.
JAMA Oncology
, 5
(4)
pp. 546-550.
10.1001/jamaoncol.2018.5441.
|
|
Shamji, MH;
Singh, I;
Layhadi, JA;
Ito, C;
Karamani, A;
Kouser, L;
Sharif, H;
... Radin, AR; + view all
(2021)
Passive Prophylactic Administration with a Single Dose of Anti-Fel d 1 Monoclonal Antibodies REGN1908-1909 in Cat Allergen-Induced Allergic Rhinitis: A Randomized, Double-blind, Placebo Controlled Trial.
American Journal of Respiratory and Critical Care Medicine
, 204
(1)
pp. 23-33.
10.1164/rccm.202011-4107OC.
|
|
|
Shao, SH;
Allen, B;
Clement, J;
Chung, G;
Gao, J;
Hubbell, E;
Liu, MC;
... Tummala, M; + view all
(2022)
Multi-cancer early detection test sensitivity for cancers with and without current population-level screening options.
Tumori
10.1177/03008916221133136.
(In press).
|
|
Shapiro, GI;
Kristeleit, RS;
Burris, HA;
LoRusso, P;
Patel, MR;
Drew, Y;
Giordano, H;
... Xiao, JJ; + view all
(2018)
Pharmacokinetic Study of Rucaparib in Patients With Advanced Solid Tumors.
Clinical Pharmacology in Drug Development
10.1002/cpdd.575.
(In press).
|
|
|
Sharif, H;
Singh, I;
Kouser, L;
Mösges, R;
Bonny, M-A;
Karamani, A;
Parkin, RV;
... Shamji, MH; + view all
(2019)
Immunologic Mechanisms of Short-course of Lolium Perenne Peptide Immunotherapy: A Randomized Double-Blind Placebo-Controlled Trial.
Journal of Allergy and Clinical Immunology
, 144
(3)
pp. 738-749.
10.1016/j.jaci.2019.02.023.
|
|
Sharma, RA;
Plummer, R;
Stock, JK;
Greenhalgh, TA;
Ataman, O;
Kelly, S;
Clay, R;
... Wedge, SR; + view all
(2016)
Clinical development of new drug-radiotherapy combinations.
NATURE REVIEWS CLINICAL ONCOLOGY
, 13
(10)
pp. 627-642.
10.1038/nrclinonc.2016.79.
|
|
|
Shawe-Taylor, Marianne;
Greenwood, David;
Hobbs, Agnieszka;
Dowgier, Giulia;
Penn, Rebecca;
Sanderson, Theo;
Stevenson-Leggett, Phoebe;
... Wall, Emma C; + view all
(2024)
Divergent performance of vaccines in the UK autumn 2023 COVID-19 booster campaign.
The Lancet
, 403
(10432)
pp. 1133-1136.
10.1016/S0140-6736(24)00316-7.
|
|
Shen, J;
Zhuang, W;
Xu, C;
Jin, K;
Chen, B;
Tian, D;
Hiley, C;
... Qiao, G; + view all
(2021)
Surgery or Non-surgical Treatment of <= 8 mm Non-small Cell Lung Cancer: A Population-Based Study.
Frontiers in Surgery
, 8
, Article ARTN 632. 10.3389/fsurg.2021.632561.
|
|
|
Shepherd, DW;
Norris, JM;
Simpson, BS;
Player, DJ;
Whitaker, HC;
(2022)
Effects of Photobiomodulation Therapy on Regulation of Myogenic Regulatory Factor mRNA Expression In Vivo: A Systematic Review.
Journal of Biophotonics
, 15
(2)
, Article e202100219. 10.1002/jbio.202100219.
|
|
Shevtsov, M;
Stangl, S;
Nikolaev, B;
Yakovleva, L;
Marchenko, Y;
Tagaeva, R;
Sievert, W;
... Multhoff, G; + view all
(2019)
Granzyme B Functionalized Nanoparticles Targeting Membrane Hsp70‐Positive Tumors for Multimodal Cancer Theranostics.
Small
, 15
(13)
, Article 1900205. 10.1002/smll.201900205.
|
|
Shovlin, CL;
Patel, D;
Bielowka, A;
Ledermann, JA;
Modarresi, A;
Bernabeu-Herrero, ME;
Aldred, MA;
(2023)
MEK 1 inhibition and bleeding in hereditary haemorrhagic telangiectasia.
British Journal of Haematology
10.1111/bjh.19167.
(In press).
|
|
Silveira, Maria Jose;
Martins, Claudia;
Cruz, Tania;
Castro, Flavia;
Amorim-Costa, Angela;
Chester, Kerry;
Oliveira, Maria Jose;
(2023)
scFv biofunctionalized nanoparticles to effective and safe targeting of CEA-expressing colorectal cancer cells.
Journal of Nanobiotechnology
, 21
(1)
, Article 357. 10.1186/s12951-023-02126-4.
|
|
Simpson, Benjamin Scott;
(2022)
Evaluating novel prognostic biomarkers in prostate cancer.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Simpson, BS;
Camacho, N;
Luxton, HJ;
Pye, H;
Finn, R;
Heavey, S;
Pitt, J;
... Whitaker, HC; + view all
(2020)
Genetic alterations in the 3q26.31-32 locus confer an aggressive prostate cancer phenotype.
Communications Biology
, 3
(1)
, Article 440. 10.1038/s42003-020-01175-x.
|
|
|
Simpson, BS;
Pye, H;
Whitaker, HC;
(2021)
The oncological relevance of fragile sites in cancer.
Communications Biology
, 4
(1)
, Article 567. 10.1038/s42003-021-02020-5.
|
|
|
Singer, R;
Campbell, P;
Fernandes, C;
Statham, P;
Hochhauser, D;
Bridgewater, J;
(2017)
Time to endoscopic intervention in patients with upper gastrointestinal patients can be improved with pathway provision.
BMC Cancer
, 17
, Article 365. 10.1186/s12885-017-3335-0.
|
|
|
Singh, Saurabh;
Mathew, Manju;
Mertzanidou, Thomy;
Suman, Shipra;
Clemente, Joey;
Retter, Adam;
Papoutsaki, Marianthi-Vasiliki;
... Punwani, Shonit; + view all
(2022)
Histo-MRI map study protocol: a prospective cohort study mapping MRI to histology for biomarker validation and prediction of prostate cancer.
BMJ Open
, 12
(4)
, Article e059847. 10.1136/bmjopen-2021-059847.
|
|
|
Singh, AN;
Oehler, J;
Torrecilla, I;
Kilgas, S;
Li, S;
Vaz, B;
Guérillon, C;
... Ramadan, K; + view all
(2019)
The p97-Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8.
The EMBO Journal
, 38
(21)
, Article e102361. 10.15252/embj.2019102361.
|
|
|
Smallman-Raynor, MR;
Cliff, AD;
Robson, SC;
Connor, TR;
Loman, NJ;
Golubchik, T;
Martinez Nunez, RT;
... Wong, N; + view all
(2022)
Spatial growth rate of emerging SARS-CoV-2 lineages in England, September 2020-December 2021.
Epidemiology & Infection
, 150
, Article e145. 10.1017/S0950268822001285.
|
|
|
Smeland, S;
Ingleby, F;
Many other authors, TPUTP;
Whelan, J;
Sydes, MR;
(2019)
Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 cohort.
European Journal of Cancer
, 109
pp. 36-50.
10.1016/j.ejca.2018.11.027.
|
|
|
Sng, CCT;
Wong, YNS;
Wu, A;
Ottaviani, D;
Chopra, N;
Galazi, M;
Benafif, S;
... Shaw, H; + view all
(2020)
Cancer History and Systemic Anti-Cancer Therapy Independently Predict COVID-19 Mortality: A UK Tertiary Hospital Experience.
Frontiers in Oncology
, 10
, Article 595804. 10.3389/fonc.2020.595804.
|
|
|
Snyder, Alexandra;
McGranahan, Nicholas;
(2022)
The importance of ancestry to understanding tumor mutation burden in cancer.
Cancer Cell
, 40
(10)
pp. 1076-1078.
10.1016/j.ccell.2022.09.004.
|
|
Sokač, Mateo;
Ahrenfeldt, Johanne;
Litchfield, Kevin;
Watkins, Thomas BK;
Knudsen, Michael;
Dyrskjøt, Lars;
Jakobsen, Martin R;
(2022)
Classifying cGAS-STING Activity Links Chromosomal Instability with Immunotherapy Response in Metastatic Bladder Cancer.
Cancer Research Communications
, 2
(8)
pp. 762-771.
10.1158/2767-9764.CRC-22-0047.
|
|
Soosaipillai, G;
Wu, A;
Dettorre, GM;
Diamantis, N;
Chester, J;
Moss, C;
Aguilar-Company, J;
... Izuzquiza, M; + view all
(2021)
Specialist palliative and end-of-life care for patients with cancer and SARS-CoV-2 infection: a European perspective.
Therapeutic Advances in Medical Oncology
, 13
pp. 1-17.
10.1177/17588359211042224.
|
|
|
Soria, JC;
Gan, HK;
Blagden, SP;
Plummer, R;
Arkenau, HT;
Ranson, M;
Evans, TRJ;
... Millward, M; + view all
(2016)
A phase I, pharmacokinetic and pharmacodynamic study of GSK2256098, a focal adhesion kinase inhibitor, in patients with advanced solid tumors.
Annals of Oncology
, 27
(12)
pp. 2268-2274.
10.1093/annonc/mdw427.
|
|
|
Soriano, EV;
Ivanova, ME;
Fletcher, G;
Riou, P;
Knowles, PP;
Barnouin, K;
Purkiss, A;
... McDonald, NQ; + view all
(2016)
aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization.
Developmental Cell
, 38
(4)
pp. 384-398.
10.1016/j.devcel.2016.07.018.
|
|
|
Spain, Lavinia;
Coulton, Alexander;
Lobon, Irene;
Rowan, Andrew;
Schnidrig, Desiree;
Shepherd, Scott TC;
Shum, Benjamin;
... Turajlic, Samra; + view all
(2023)
Late-Stage Metastatic Melanoma Emerges through a Diversity of Evolutionary Pathways.
Cancer Discovery
, 13
(6)
pp. 1364-1385.
10.1158/2159-8290.CD-22-1427.
|
|
|
Spanswick, VJ;
Craddock, C;
Sekhar, M;
Mahendra, P;
Shankaranarayana, P;
Hughes, RG;
Hochhauser, D;
(2002)
Repair of DNA interstrand crosslinks as a mechanism of clinical resistance to melphalan in multiple myeloma.
BLOOD
, 100
(1)
224 - 229.
|
|
|
Spanswick, VJ;
Lowe, HL;
Newton, C;
Bingham, JP;
Bagnobianchi, A;
Kiakos, K;
Craddock, C;
... Hartley, JA; + view all
(2012)
Evidence for different mechanisms of 'unhooking' for melphalan and cisplatin-induced DNA interstrand cross-links in vitro and in clinical acquired resistant tumour samples.
BMC Cancer
, 12
, Article 436. 10.1186/1471-2407-12-436.
|
|
|
Spicer, J;
Irshad, S;
Ang, JE;
Enting, D;
Kristeleit, RS;
Uttenreuther-Fischer, M;
Pemberton, K;
... De Bono, J; + view all
(2017)
A phase I study of afatinib combined with paclitaxel and bevacizumab in patients with advanced solid tumors.
Cancer Chemotherapy and Pharmacology
, 79
(1)
pp. 17-27.
10.1007/s00280-016-3189-1.
|
|
|
Spicer, JF;
Baurain, JF;
Awada, A;
Kristeleit, RS;
Jossang, DE;
Marabelle, A;
Loirat, D;
... Brunsvig, P; + view all
(2017)
LTX-315, an oncolytic peptide, to convert immunogenically 'cold' tumors to 'hot' in patients with advanced or metastatic tumours: Results from an ongoing phase I study.
Presented at: American Society of Clinical Oncology Annual Meeting 2017, Chicago, IL, USA.
(In press).
|
|
Stacchiotti, S;
Maria Frezza, A;
Demetri, GD;
Blay, JY;
Bajpai, J;
Baldi, GG;
Baldini, EH;
... Wagner, AJ; + view all
(2022)
Retrospective observational studies in ultra-rare sarcomas: A consensus paper from the Connective Tissue Oncology Society (CTOS) community of experts on the minimum requirements for the evaluation of activity of systemic treatments.
Cancer Treatment Reviews
, 110
, Article 102455. 10.1016/j.ctrv.2022.102455.
|
|
Stacchiotti, S;
Miah, AB;
Frezza, AM;
Messiou, C;
Morosi, C;
Caraceni, A;
Antonescu, CR;
... Gronchi, A; + view all
(2021)
Enithelioid hemangioendothelioma, an ultra-rare cancer: a consensus paper from the community of experts.
ESMO OPEN
, 6
(3)
, Article 100170. 10.1016/j.esmoop.2021.100170.
|
|
|
Stark, A-K;
Davenport, ECM;
Patton, DT;
Scudamore, CL;
Vanhaesebroeck, B;
Veldhoen, M;
Garden, OA;
(2020)
Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation.
The Journal of Immunology
10.4049/jimmunol.2000043.
(In press).
|
|
|
Starkey, Thomas;
Ionescu, Maria;
Tilby, Michael;
Little, Martin W;
Burke, Emma;
Fittall, Matthew;
Khan, Sam R;
... NCRI, Consumer Forum; + view all
(2023)
A population-scale temporal case-control evaluation of COVID-19 disease phenotype and related outcome rates in patients with cancer in England (UKCCP).
Scientific Reports
, 13
(1)
, Article 11327. 10.1038/s41598-023-36990-9.
|
|
Stavrinides, Vasilis;
Eksi, Ece;
Finn, Ron;
Texeira-Mendes, Larissa;
Rana, Sarina;
Trahearn, Nick;
Grey, Alistair;
... Orczyk, Clement; + view all
(2023)
Magnetic Resonance Imaging Follow-up of Targeted Biopsy-negative Prostate Lesions.
European Urology Focus
10.1016/j.euf.2023.03.011.
(In press).
|
|
Stavrinides, Vasilis;
Norris, Joseph M;
Karapanagiotis, Solon;
Giganti, Francesco;
Grey, Alistair;
Trahearn, Nick;
Freeman, Alex;
... PROMIS Group; + view all
(2023)
Regional Histopathology and Prostate MRI Positivity: A Secondary Analysis of the PROMIS Trial.
Radiology
, 307
(1)
, Article 220762. 10.1148/radiol.220762.
|
|
Steele, Christopher D;
Abbasi, Ammal;
Islam, SM Ashiqul;
Bowes, Amy L;
Khandekar, Azhar;
Haase, Kerstin;
Hames-Fathi, Shadi;
... Pillay, Nischalan; + view all
(2022)
Signatures of copy number alterations in human cancer.
Nature
10.1038/s41586-022-04738-6.
(In press).
|
|
Steele, CD;
Tarabichi, M;
Oukrif, D;
Webster, AP;
Ye, H;
Fittall, M;
Lombard, P;
... Pillay, N; + view all
(2019)
Undifferentiated Sarcomas Develop through Distinct Evolutionary Pathways.
Cancer Cell
, 35
(3)
441-456.e8.
10.1016/j.ccell.2019.02.002.
|
|
|
Stefano, P;
Ivana, M;
Arianna, G;
Letizia, Z;
Angelo, G;
Rosella, C;
Roberta, B;
... Andrea, G; + view all
(2019)
Identification of microRNAs and relative target genes in Moringa oleifera leaf and callus.
Scientific Reports
, 9
, Article 15145. 10.1038/s41598-019-51100-4.
|
|
|
Stein, A;
Dalton, L;
Rapa, E;
Bluebond-Langner, M;
Hanington, L;
Stein, KF;
Ziebland, S;
... Yousafzai, A; + view all
(2019)
Communication with children and adolescents about the diagnosis of their own life-threatening condition.
The Lancet
, 393
(10176)
pp. 1150-1163.
10.1016/S0140-6736(18)33201-X.
|
|
Stein, RC;
Dunn, JA;
Bartlett, JMS;
Campbell, AF;
Marshall, A;
Hall, P;
Rooshenas, L;
+ view all
(2016)
OPTIMA: a randomised feasibility study of personalised care in the treatment of women with early breast cancer.
(Health Technology Assessment
20(10)
, pp. pp. 1-202
).
National Institute of Health Research: UK.
|
|
|
Strasser, S;
Abou-Alfa, G;
Mollon, P;
Meyer, T;
Cheng, A;
El-Khoueiry, A;
Kelley, R;
... Freemantle, N; + view all
(2019)
Quality-adjusted life-years accrued with cabozantinib in patients with advanced hepatocellular carcinoma in the CELESTIAL trial.
Presented at: Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “The Universe Within”, Adelaide, Australia.
|
|
Strauss, Sandra;
(2023)
Incidence and survival of soft tissue sarcoma in England between 2013-2017, an analysis from the National Cancer Registration and Analysis Service.
International Journal of Cancer
, 152
(9)
pp. 1789-1803.
10.1002/ijc.34409.
|
|
Strauss, Sandra J;
Berlanga, Pablo;
McCabe, Martin G;
(2024)
Emerging therapies in Ewing sarcoma.
Current Opinion in Oncology
, 36
(4)
pp. 297-304.
10.1097/CCO.0000000000001048.
|
|
Strauss, SJ;
Frezza, AM;
Abecassis, N;
Bajpai, J;
Bauer, S;
Biagini, R;
Bielack, S;
... Stacchiotti, S; + view all
(2021)
Bone sarcomas: ESMO-EURACAN-GENTURIS-ERN PaedCan Clinical Practice Guideline for diagnosis, treatment and follow-up.
Annals of Oncology
, 32
(12)
pp. 1520-1536.
10.1016/j.annonc.2021.08.1995.
|
|
Strauss, SJ;
Anninga, J;
Baglio, R;
Baumhoer, D;
Behjati, S;
Bielack, S;
Boye, K;
... Whelan, J; + view all
(2018)
Report from the 4th European Bone Sarcoma Networking meeting: focus on osteosarcoma.
Clinical Sarcoma Research
, 8
, Article 17. 10.1186/s13569-018-0103-0.
|
|
|
Strauss, SJ;
Whelan, JS;
(2018)
Current questions in bone sarcomas.
Current Opinion in Oncology
, 30
(4)
pp. 252-259.
10.1097/CCO.0000000000000456.
|
|
Sud, A;
Jones, M;
Broggio, J;
Loveday, C;
Torr, B;
Garrett, A;
Nicol, DL;
... Turnbull, C; + view all
(2020)
Collateral damage: the impact on outcomes from cancer surgery of the COVID-19 pandemic.
Annals of Oncology
10.1016/j.annonc.2020.05.009.
(In press).
|
|
|
Sud, A;
Torr, B;
Jones, ME;
Broggio, J;
Scott, S;
Loveday, C;
Garrett, A;
... Turnbull, C; + view all
(2020)
Effect of delays in the 2-week-wait cancer referral pathway during the COVID-19 pandemic on cancer survival in the UK: a modelling study.
The Lancet Oncology
, 21
(8)
pp. 1035-1044.
10.1016/S1470-2045(20)30392-2.
|
|
|
Suddle, Abid;
Reeves, Helen;
Hubner, Richard;
Marshall, Aileen;
Rowe, Ian;
Tiniakos, Dina;
Hubscher, Stefan;
... Meyer, Tim; + view all
(2024)
British Society of Gastroenterology guidelines for the management of hepatocellular carcinoma in adults.
Gut
10.1136/gutjnl-2023-331695.
(In press).
|
|
Sufi, J;
Qin, X;
Rodriguez, FC;
Bu, YJ;
Vlckova, P;
Zapatero, MR;
Nitz, M;
(2021)
Multiplexed single-cell analysis of organoid signaling networks.
Nature Protocols
, 16
pp. 4897-4918.
10.1038/s41596-021-00603-4.
|
|
Suh, Y-E;
Lawler, K;
Henley-Smith, R;
Pike, L;
Leek, R;
Barrington, S;
Odell, EW;
... Tavassoli, M; + view all
(2017)
Association between hypoxic volume and underlying hypoxia-induced gene expression in oropharyngeal squamous cell carcinoma.
British Journal of Cancer
, 116
(8)
pp. 1057-1064.
10.1038/bjc.2017.66.
|
|
Sullivan, R;
Heavey, S;
Graham, DG;
Wellman, R;
Khan, S;
Thrumurthy, S;
Simpson, BS;
... Lovat, LB; + view all
(2020)
An optimised saliva collection method to produce high-yield, high-quality RNA for translational research.
PLOS ONE
, 15
(3)
, Article e0229791. 10.1371/journal.pone.0229791.
|
|
|
Suman, M;
Sharpe, JA;
Bentham, RB;
Kotiadis, VN;
Menegollo, M;
Pignataro, V;
Molgó, J;
... Szabadkai, G; + view all
(2018)
Inositol Trisphosphate Receptor Mediated Ca2+ Signalling Stimulates Mitochondrial Function and Gene Expression in Core Myopathy Patients.
Human Molecular Genetics
, 27
(13)
pp. 2367-2382.
10.1093/hmg/ddy149.
|
|
Sumanasuriya, S;
Omlin, A;
Armstrong, A;
Attard, G;
Chi, KN;
Bevan, CL;
Shibakawa, A;
... de Bono, JS; + view all
(2018)
Consensus Statement on Circulating Biomarkers for Advanced Prostate Cancer.
European Urology Oncology
, 1
(2)
pp. 151-159.
10.1016/j.euo.2018.02.009.
|
|
|
Sun, H;
Cao, S;
Mashl, RJ;
Mo, C-K;
Zaccaria, S;
Wendl, MC;
Davies, SR;
... Ding, L; + view all
(2021)
Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment.
Nature Communications
, 12
, Article 5086. 10.1038/s41467-021-25177-3.
|
|
Sundar, Sudha;
Nordin, Andy;
Morrison, Jo;
Wood, Nick;
Ghaem-Maghami, Sadaf;
Nieto, Jo;
Phillips, Andrew;
... Fotopoulou, Christina; + view all
(2023)
British Gynaecological Cancer Society Recommendations for Evidence Based, Population Data Derived Quality Performance Indicators for Ovarian Cancer.
Cancers
, 15
(2)
, Article 337. 10.3390/cancers15020337.
|
|
Sundquist, F;
Georgantzi, K;
Jarvis, KB;
Brok, J;
Koskenvuo, M;
Rascon, J;
van Noesel, M;
... Stenman, J; + view all
(2022)
A Phase II Trial of a Personalized, Dose-Intense Administration Schedule of 177Lutetium-DOTATATE in Children With Primary Refractory or Relapsed High-Risk Neuroblastoma–LuDO-N.
Frontiers in Pediatrics
, 10
, Article 836230. 10.3389/fped.2022.836230.
|
|
Sutera, Philip;
Van Der Eecken, Kim;
Kishan, Amar U;
Hamid, Anis;
Grist, Emily;
Attard, Gerhardt;
Lotan, Tamara;
... Deek, Matthew P; + view all
(2022)
Definitions of disease burden across the spectrum of metastatic castration-sensitive prostate cancer: comparison by disease outcomes and genomics.
Prostate Cancer and Prostatic Diseases
, 25
(4)
pp. 713-719.
10.1038/s41391-021-00484-4.
|
|
Swanton, C;
Beck, SA;
(2014)
Epigenetic noise fuels cancer evolution.
Cancer Cell
, 26
(6)
pp. 775-776.
10.1016/j.ccell.2014.11.003.
|
|
|
Swanton, C;
Govindan, R;
(2016)
Clinical Implications of Genomic Discoveries in Lung Cancer.
New England Journal of Medicine
, 374
(19)
pp. 1864-1873.
10.1056/NEJMra1504688.
|
|
|
Sweeney, Christopher J;
Hainsworth, John D;
Bose, Ron;
Burris, Howard A;
Kurzrock, Razelle;
Swanton, Charles;
Friedman, Claire F;
... Meric-Bernstam, Funda; + view all
(2024)
MyPathway Human Epidermal Growth Factor Receptor 2 Basket Study: Pertuzumab + Trastuzumab Treatment of a Tissue-Agnostic Cohort of Patients With Human Epidermal Growth Factor Receptor 2–Altered Advanced Solid Tumors.
Journal of Clinical Oncology
, 42
(3)
pp. 258-265.
10.1200/JCO.22.02636.
|
|
|
Swisher, E;
Harrell, MI;
Lin, KK;
Scott, CL;
Goble, S;
Oza, A;
Coleman, RL;
... Kaufmann, S; + view all
(2017)
BRCA1 and RAD51C Promoter Hypermethylation Confer Sensitivity to PARP Inhibitors in Patients with Platinum Sensitive Ovarian Carcinoma.
Clinical Cancer Research
, 23
(11 Suppl)
10.1158/1557-3265.OVCASYMP16-AP28.
|
|
Swisher, EM;
Lin, KK;
Oza, AM;
Scott, CL;
Giordano, H;
Sun, J;
Konecny, GE;
... McNeish, IA; + view all
(2017)
Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial.
Lancet Oncology
, 18
(1)
pp. 75-87.
10.1016/S1470-2045(16)30559-9.
|
|
|
Sydes, MR;
(2018)
Adding abiraterone or docetaxel to long-term hormone therapy for prostate cancer: directly randomised data from the STAMPEDE multi-arm, multi-stage platform protocol.
Annals Of Oncology
, 29
(5)
pp. 1235-1248.
10.1093/annonc/mdy072.
|
|
|
Szikriszt, B;
Póti, Á;
Németh, E;
Kanu, N;
Swanton, C;
Szüts, D;
(2021)
A comparative analysis of the mutagenicity of platinum-containing chemotherapeutic agents reveals direct and indirect mutagenic mechanisms.
Mutagenesis
, 36
(1)
pp. 75-86.
10.1093/mutage/geab005.
|
|
|
Szikriszt, B;
Poti, A;
Pipek, O;
Krzystanek, M;
Kanu, N;
Molnar, J;
Ribli, D;
... Szuts, D; + view all
(2016)
A comprehensive survey of the mutagenic impact of common cancer cytotoxics.
Genome Biology
, 17
, Article 99. 10.1186/s13059-016-0963-7.
|
|
|
Szmul, Adam;
Chandy, Edward;
Veiga, Catarina;
Jacob, Joseph;
Stavropoulou, Alkisti;
Landau, David;
Hiley, Crispin T;
(2022)
A Novel and Automated Approach to Classify Radiation Induced Lung Tissue Damage on CT Scans.
Cancers
, 14
(5)
, Article 1341. 10.3390/cancers14051341.
|
|
|
Szyszko, TA;
Dunn, JT;
Phillips, MM;
Bomalaski, J;
Sheaff, MT;
Ellis, S;
Pike, L;
... Szlosarek, PW; + view all
(2022)
Role of 3'-Deoxy-3'-[¹⁸F] Fluorothymidine Positron Emission Tomography-Computed Tomography as a Predictive Biomarker in Argininosuccinate Synthetase 1-Deficient Thoracic Cancers Treated With Pegargiminase.
JTO Clinical and Research Reports
, 3
(9)
, Article 100382. 10.1016/j.jtocrr.2022.100382.
|
T
|
Taavitsainen, S;
Engedal, N;
Cao, S;
Handle, F;
Erickson, A;
Prekovic, S;
Wetterskog, D;
... Urbanucci, A; + view all
(2021)
Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse.
Nature Communications
, 12
(1)
, Article 5307. 10.1038/s41467-021-25624-1.
|
|
|
Tabernero, J;
Alsina, M;
Shitara, K;
Doi, T;
Dvorkin, M;
Mansoor, W;
Arkenau, H-T;
... Ilson, DH; + view all
(2020)
Health-related quality of life associated with trifluridine/tipiracil in heavily pretreated metastatic gastric cancer: results from TAGS.
Gastric Cancer
10.1007/s10120-020-01053-9.
|
|
|
Tabernero, J;
Grothey, A;
Van Cutsem, E;
Yaeger, R;
Wasan, H;
Yoshino, T;
Desai, J;
... Kopetz, S; + view all
(2021)
Encorafenib Plus Cetuximab as a New Standard of Care for Previously Treated BRAF V600E–Mutant Metastatic Colorectal Cancer: Updated Survival Results and Subgroup Analyses from the BEACON Study.
Journal of Clinical Oncology
, 39
(4)
pp. 273-284.
10.1200/JCO.20.02088.
|
|
|
Tabish, TA;
Abbas, A;
Narayan, RJ;
(2021)
Graphene nanocomposites for transdermal biosensing.
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology
, 13
(4)
, Article e1699. 10.1002/wnan.1699.
|
|
Tabish, TA;
Hamblin, MR;
(2020)
Multivalent nanomedicines to treat COVID-19: A slow train coming.
Nano Today
, 35
, Article 100962. 10.1016/j.nantod.2020.100962.
|
|
Tabish, TA;
Narayan, RJ;
Edirisinghe, M;
(2020)
Rapid and label-free detection of COVID-19 using coherent anti-Stokes Raman scattering microscopy.
MRS Communications
, 10
(4)
pp. 566-572.
10.1557/mrc.2020.81.
|
|
Taccioli, C;
Maselli, V;
Tegnér, J;
Gomez-Cabrero, D;
Altobelli, G;
Emmett, W;
Lescai, F;
... Stupka, E; + view all
(2011)
ParkDB: a Parkinson's disease gene expression database.
Database
, 2011
(May 20)
, Article bar007. 10.1093/database/bar007.
|
|
|
Tan, MP;
Attard, G;
Huddart, RA;
(2018)
Circulating Tumour DNA in Muscle-Invasive Bladder Cancer.
International Journal of Molecular Sciences
, 19
(9)
, Article 2568. 10.3390/ijms19092568.
|
|
|
Tang, WHW;
Yimer, H;
Tummala, M;
Shao, S;
Chung, G;
Clement, J;
Chu, BC;
... Roberts, LR; + view all
(2023)
Performance of a targeted methylation-based multi-cancer early detection test by race and ethnicity.
Preventive Medicine
, 167
, Article 107384. 10.1016/j.ypmed.2022.107384.
|
|
Taniere, Phillipe;
Nicholson, Andrew G;
Gosney, John R;
Montero Fernandez, Maria Angeles;
Bury, Danielle;
Moore, David Allan;
Verghese, Eldo;
... Ryan, Jacqueline; + view all
(2023)
Landscape of cancer biomarker testing in England following genomic services reconfiguration: insights from a nationwide pathologist survey.
Journal of Clinical Pathology
10.1136/jcp-2023-208890.
(In press).
|
|
Tape, Christopher J;
(2023)
Plastic persisters: revival stem cells in colorectal cancer.
Trends in Cancer
10.1016/j.trecan.2023.11.003.
(In press).
|
|
Tape, CJ;
(2017)
The Heterocellular Emergence of Colorectal Cancer.
Trends Cancer
, 3
(2)
pp. 79-88.
10.1016/j.trecan.2016.12.004.
|
|
|
Tape, CJ;
Ling, S;
Dimitriadi, M;
McMahon, KM;
Worboys, JD;
Leong, HS;
Norrie, IC;
... Jorgensen, C; + view all
(2016)
Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation.
Cell
, 165
(4)
pp. 910-920.
10.1016/j.cell.2016.03.029.
|
|
|
Taylor, Alexandra;
Sundar, Sudha S;
Bowen, Rebecca;
Clayton, Rick;
Coleridge, Sarah;
Fotopoulou, Christina;
Ghaem-Maghami, Sadaf;
... Morrison, Jo; + view all
(2022)
British Gynaecological Cancer Society Recommendations for Women With Gynecological Cancer Who Received Non-standard Care During the COVID-19 Pandemic.
Obstetrical and Gynecological Survey
, 77
(3)
pp. 156-157.
10.1097/01.ogx.0000822432.56370.10.
|
|
Taylor, SA;
Mallett, S;
Beare, S;
Bhatnagar, G;
Blunt, D;
Boavida, P;
Bridgewater, J;
... Streamline investigators; + view all
(2019)
Diagnostic accuracy of whole-body MRI versus standard imaging pathways for metastatic disease in newly diagnosed colorectal cancer: the prospective Streamline C trial.
The Lancet Gastroenterology & Hepatology
, 4
(7)
pp. 529-537.
10.1016/S2468-1253(19)30056-1.
|
|
|
Teixeira, VH;
Pipinikas, CP;
Pennycuick, A;
Lee-Six, H;
Chandrasekharan, D;
Beane, J;
Morris, TJ;
... Janes, SM; + view all
(2019)
Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions.
Nature Medicine
, 25
pp. 517-525.
10.1038/s41591-018-0323-0.
|
|
Terrisse, AD;
Laurent, PA;
Garcia, C;
Gratacap, MP;
Vanhaesebroeck, B;
Sié, P;
Payrastre, B;
(2016)
The class I phosphoinositide 3-kinases α and β control antiphospholipid antibodies-induced platelet activation.
Thrombosis and Haemostasis
10.1160/TH15-08-0661.
|
|
Terwisscha van Scheltinga, SEJ;
Wijnen, MHWA;
Martelli, H;
Rogers, T;
Mandeville, H;
Gaze, MN;
McHugh, K;
... Merks, HHM; + view all
(2020)
Local staging and treatment in extremity rhabdomyosarcoma. A report from the EpSSG-RMS2005 study.
Cancer Medicine
, 9
(20)
pp. 7580-7589.
10.1002/cam4.3365.
|
|
Terziev, R;
Psimaras, D;
Marie, Y;
Feuvret, L;
Berzero, G;
Jacob, J;
Dehais, C;
... Ricard, D; + view all
(2021)
Cumulative incidence and risk factors for radiation induced leukoencephalopathy in high grade glioma long term survivors.
Scientific Reports
, 11
(1)
, Article 10176. 10.1038/s41598-021-89216-1.
|
|
Teschendorff, AE;
Lee, SH;
Jones, A;
Fiegl, H;
Kalwa, M;
Wagner, W;
Chindera, K;
... Widschwendter, M; + view all
(2015)
HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer.
Genome Medicine
, 7
(1)
, Article 108. 10.1186/s13073-015-0233-4.
|
|
|
Teschendorff, AE;
Marabita, F;
Lechner, M;
Bartlett, T;
Tegner, J;
Gomez-Cabrero, D;
Beck, S;
(2013)
A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data.
Bioinformatics
, 29
(2)
189 - 196.
10.1093/bioinformatics/bts680.
|
|
|
Tesson, Mathias;
Rae, Colin;
L Nile, Donna;
N Gaze, Mark;
J. Mairs, Robert;
(2017)
Targeted radiotherapy of neuroblastoma: Future directions.
Integrative Cancer Science and Therapeutics
, 4
(5)
pp. 1-2.
10.15761/icst.1000260.
|
|
|
Thagaard, J;
Broeckx, G;
Page, DB;
Jahangir, CA;
Verbandt, S;
Kos, Z;
Gupta, R;
... Reis-Filho, JS; + view all
(2023)
Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: a report of the international immuno-oncology biomarker working group.
Journal of Pathology
, 260
(5)
pp. 498-513.
10.1002/path.6155.
|
|
The UK Coronavirus Cancer Monitoring Project team;
(2020)
The UK Coronavirus Cancer Monitoring Project: protecting patients with cancer in the era of COVID-19.
The Lancet Oncology
, 21
(5)
pp. 622-624.
10.1016/S1470-2045(20)30230-8.
|
|
Therond, C;
Lanceley, A;
Gibbon, S;
Rahman, B;
(2020)
The narrative paradox of the BRCA gene: An ethnographic study in the clinical encounters of ovarian cancer patients.
Anthropology & Medicine
, 27
(4)
pp. 449-464.
10.1080/13648470.2019.1663784.
|
|
Thirlwell, C.;
(2006)
Mechanisms of colorectal tumorigenesis associated with Mut-Y (MYH) deficiency and identification of novel predisposition genes in the multiple adenoma phenotype.
Doctoral thesis , University of London.
|
|
|
Thistlethwaite, FC;
Gilham, DE;
Guest, RD;
Rothwell, DG;
Pillai, M;
Burt, DJ;
Byatte, AJ;
... Hawkins, RE; + view all
(2017)
The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity.
Cancer Immunology, Immunotherapy
10.1007/s00262-017-2034-7.
(In press).
|
|
|
Thol, K;
McGranahan, N;
(2021)
Potential Use of Shared Frameshift Mutations in 'Off-the-Shelf' Neoantigen Vaccines.
Trends in Cancer
, 7
(3)
pp. 175-177.
10.1016/j.trecan.2021.01.002.
|
|
Thol, K;
Pawlik, P;
McGranahan, N;
(2022)
Therapy sculpts the complex interplay between cancer and the immune system during tumour evolution.
Genome Medicine
, 14
, Article 137. 10.1186/s13073-022-01138-3.
|
|
Thomas, Maya;
Murali, Sanjana;
Simpson, Benjamin Scott S;
Freeman, Alex;
Kirkham, Alex;
Kelly, Daniel;
Whitaker, Hayley C;
... Norris, Joseph M; + view all
(2023)
Use of artificial intelligence in the detection of primary prostate cancer in multiparametric MRI with its clinical outcomes: a protocol for a systematic review and meta-analysis.
BMJ Open
, 13
(8)
, Article e074009. 10.1136/bmjopen-2023-074009.
|
|
Tibarewal, Priyanka;
Rathbone, Victoria;
Constantinou, Georgia;
Pearce, Wayne;
Adil, Mahreen;
Varyova, Zofia;
Folkes, Lisa;
... Vanhaesebroeck, Bart; + view all
(2022)
Long-term treatment of cancer-prone germline PTEN mutant mice with low-dose rapamycin extends lifespan and delays tumour development.
The Journal of Pathology
10.1002/path.6009.
(In press).
|
|
Tirotta, Fabio;
Bacon, Andrew;
Collins, Shane;
Desai, Anant;
Liu, Hanhua;
Paley, Lizz;
Strauss, Dirk;
(2023)
Primary retroperitoneal sarcoma: A comparison of survival outcomes in specialist and non-specialist sarcoma centres.
European Journal of Cancer
, 188
pp. 20-28.
10.1016/j.ejca.2023.04.004.
|
|
Tomas, A;
Jones, S;
Vaughan, SO;
Hochhauser, D;
Futter, CE;
(2017)
Stress-specific p38 MAP kinase activation is sufficient to drive EGF receptor endocytosis but not nuclear translocation.
Journal of Cell Science
, 130
(15)
pp. 2481-2490.
10.1242/jcs.202358.
|
|
|
Tombal, B;
Saad, F;
Penson, D;
Hussain, M;
Sternberg, CN;
Morlock, R;
Ramaswamy, K;
... Attard, G; + view all
(2019)
Patient-reported outcomes following enzalutamide or placebo in men with non-metastatic, castration-resistant prostate cancer (PROSPER): a multicentre, randomised, double-blind, phase 3 trial.
Lancet Oncology
, 20
(4)
pp. 556-569.
10.1016/S1470-2045(18)30898-2.
|
|
Tommasini, Fabio;
Benoist, Thomas;
Shibuya, Soichi;
Woodall, Maximillian NJ;
Naldi, Eleonora;
Palor, Machaela;
Orr, Jessica C;
... De Coppi, Paolo; + view all
(2023)
Lung viral infection modelling in a bioengineered whole-organ.
Biomaterials
, 301
, Article 122203. 10.1016/j.biomaterials.2023.122203.
|
|
Tosatto, A;
Sommaggio, R;
Kummerow, C;
Bentham, RB;
Blacker, TS;
Berecz, T;
Duchen, MR;
... Mammucari, C; + view all
(2016)
The mitochondrial calcium uniporter regulates breast cancer progression via HIF-1α.
EMBO Molecular Medicine
, 8
(5)
pp. 569-585.
10.15252/emmm.201606255.
|
|
|
Tran, Hoang Son;
(2023)
Integrating multi-omics data by mapping subclonal events on tumour evolutionary trees.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
|
Trebeschi, S;
Drago, SG;
Birkbak, NJ;
Kurilova, I;
Calin, AM;
Pizzi, AD;
Lalezari, F;
... Aerts, HJWL; + view all
(2019)
Predicting response to cancer immunotherapy using noninvasive radiomic biomarkers.
Annals of Oncology
, 30
(6)
pp. 998-1004.
10.1093/annonc/mdz108.
|
|
|
Trujillo, Blanca;
Wu, Anjui;
Wetterskog, Daniel;
Attard, Gerhardt;
(2022)
Blood-based liquid biopsies for prostate cancer: clinical opportunities and challenges.
British Journal of Cancer
10.1038/s41416-022-01881-9.
(In press).
|
|
Turajlic, S;
Litchfield, K;
Xu, H;
Rosenthal, R;
McGranahan, N;
Reading, JL;
Wong, YNS;
... Swanton, C; + view all
(2017)
Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis.
The Lancet Oncology
, 18
(8)
pp. 1009-1021.
10.1016/S1470-2045(17)30516-8.
|
|
|
Turajlic, S;
Swanton, C;
Boshoff, C;
(2018)
Kidney cancer: The next decade.
Journal of Experimental Medicine
, 215
(9)
10.1084/jem.20181617.
|
|
|
Turajlic, S;
Xu, H;
Litchfield, K;
Rowan, A;
Chambers, T;
Lopez, JI;
Nicol, D;
... Swanton, C; + view all
(2018)
Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal.
Cell
, 173
(3)
581-594.e12.
10.1016/j.cell.2018.03.057.
|
|
|
Turajlic, S;
Xu, H;
Litchfield, K;
Rowan, A;
Horswell, S;
Chambers, T;
O'Brien, T;
... TRACERx Renal Consortium, .; + view all
(2018)
Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal.
Cell
, 173
(3)
595-610.e11.
10.1016/j.cell.2018.03.043.
|
|
|
Turcas, A;
Kelly, SM;
Bernier-Chastagner, V;
Bolle, S;
Cameron, A;
Corning, C;
Clementel, E;
... Mandeville, HC; + view all
(2023)
Management of the vertebrae as an organ at risk in paediatric radiotherapy clinical trials: Initial QUARTET experience.
Radiotherapy and Oncology
, 187
, Article 109810. 10.1016/j.radonc.2023.109810.
|
|
Turri-Zanoni, M;
Dalfino, G;
Lechner, M;
Dallan, I;
Battaglia, P;
Facco, C;
Franzi, F;
... Castelnuovo, P; + view all
(2022)
Biphenotypic sinonasal sarcoma: European multicentre case-series and systematic literature review.
Acta Otorhinolaryngologica Italica
, 42
(6)
pp. 545-553.
10.14639/0392-100X-N2087.
|
U
|
Uccello, M;
Moschetta, M;
Mak, G;
Alam, T;
Henriquez, CM;
Arkenau, H-T;
(2018)
Towards an optimal treatment algorithm for metastatic pancreatic ductal adenocarcinoma (PDA).
Current Oncology
, 25
(1)
e90-e94.
10.3747/co.25.3708.
|
|
|
Uddin, I;
Joshi, K;
Oakes, T;
Heather, JM;
Swanton, C;
TRACERx consortium, .;
Chain, B;
(2019)
An Economical, Quantitative, and Robust Protocol for High-Throughput T Cell Receptor Sequencing from Tumor or Blood.
Cancer Immunosurveillance: Methods and Protocols
pp. 15-42.
10.1007/978-1-4939-8885-3_2.
|
|
Uddin, I;
Woolston, A;
Peacock, T;
Joshi, K;
Ismail, M;
Ronel, T;
Husovsky, C;
(2019)
Quantitative analysis of the T cell receptor repertoire.
Methods in Enzymology
, 629
pp. 465-492.
10.1016/bs.mie.2019.05.054.
|
|
Usaite, Ieva;
Biswas, Dhruva;
Dijkstra, Krijn;
Watkins, Thomas Bk;
Pich, Oriol;
Puttick, Clare;
Angelova, Mihaela;
... Kanu, Nnennaya; + view all
(2023)
Quantifying the impact of immunotherapy on RNA dynamics in cancer.
Journal for ImmunoTherapy of Cancer
, 11
(11)
, Article e007870. 10.1136/jitc-2023-007870.
|
|
V
|
Vaarwerk, Bas;
Schoot, Reineke A;
Maurice-Stam, Heleen;
Slater, Olga;
Hartley, Benjamin;
Saeed, Peerooz;
Gajdosova, Eva;
... Merks, Johannes HM; + view all
(2019)
Psychosocial well-being of long-term survivors of pediatric head-neck rhabdomyosarcoma.
Pediatric Blood & Cancer
, 66
(2)
, Article e27498. 10.1002/pbc.27498.
|
|
|
Valet, C;
Levade, M;
Chicanne, G;
Bilanges, B;
Cabou, C;
Viaud, J;
Gratacap, M-P;
... Severin, S; + view all
(2017)
A dual role for the class III PI3K, Vps34, in platelet production and thrombus growth.
Blood
, 130
(18)
pp. 2032-2042.
10.1182/blood-2017-04-781641.
|
|
van der Noll, R;
Jager, A;
Ang, JE;
Marchetti, S;
Mergui-Roelvink, MWJ;
de Bono, JS;
Lolkema, MP;
... Schellens, JHM; + view all
(2020)
Phase I study of intermittent olaparib capsule or tablet dosing in combination with carboplatin and paclitaxel (part 2).
Investigational New Drugs
, 38
pp. 1096-1107.
10.1007/s10637-019-00857-6.
|
|
van der Noll, R;
Jager, A;
Ang, JE;
Marchetti, S;
Mergui-Roelvink, MWJ;
Lolkema, MP;
de Jonge, MJA;
... Schellens, JHM; + view all
(2020)
Phase I study of continuous olaparib capsule dosing in combination with carboplatin and/or paclitaxel (Part 1).
Investigational New Drugs
, 38
pp. 1117-1128.
10.1007/s10637-019-00856-7.
|
|
van Ewijk, R;
Herold, N;
Baecklund, F;
Baumhoer, D;
Boye, K;
Gaspar, N;
Harrabi, SB;
... Kager, L; + view all
(2023)
European standard clinical practice recommendations for children and adolescents with primary and recurrent osteosarcoma.
EJC Paediatric Oncology
, 2
, Article 100029. 10.1016/j.ejcped.2023.100029.
|
|
|
van Ewijk, Roelof;
Cleirec, Morgane;
Herold, Nikolas;
le Deley, Marie-Cécile;
van Eijkelenburg, Natasha;
Boudou-Rouquette, Pascaline;
Risbourg, Séverine;
... FOSTER Consortium, .; + view all
(2023)
A systematic review of recent phase-II trials in refractory or recurrent osteosarcoma: Can we inform future trial design?
Cancer Treatment Reviews
, 120
, Article 102625. 10.1016/j.ctrv.2023.102625.
(In press).
|
|
|
van Maldegem, F;
Valand, K;
Cole, M;
Patel, H;
Angelova, M;
Rana, S;
Colliver, E;
... Downward, J; + view all
(2021)
Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry.
Nature Communications
, 12
(1)
, Article 5906. 10.1038/s41467-021-26214-x.
|
|
|
van Noesel, MM;
Orbach, D;
Brennan, B;
Kelsey, A;
Zanetti, I;
de Salvo, GL;
Gaze, MN;
... Ferrari, A; + view all
(2019)
Outcome and prognostic factors in pediatric malignant peripheral nerve sheath tumors: An analysis of the European Pediatric Soft Tissue Sarcoma Group (EpSSG) NRSTS-2005 prospective study.
Pediatric Blood and Cancer
, 66
(10)
, Article e27833. 10.1002/pbc.27833.
|
|
|
Vanhaesebroeck, B;
Perry, MWD;
Brown, JR;
André, F;
Okkenhaug, K;
(2021)
PI3K inhibitors are finally coming of age.
Nature Reviews Drug Discovery
, 20
pp. 741-769.
10.1038/s41573-021-00209-1.
|
|
Vanhaesebroeck, Bart;
(2024)
30 years of PI3K: an interview with Bart Vanhaesebroeck.
Future Oncology
, 20
(20)
pp. 1381-1384.
10.2217/fon-2024-0215.
|
|
Vanhaesebroeck, Bart;
Burke, John E;
Madsen, Ralitsa R;
(2022)
Precision Targeting of Mutant PI3Kα in Cancer by Selective Degradation.
Cancer Discovery
, 12
(1)
pp. 20-22.
10.1158/2159-8290.CD-21-1411.
|
|
Vanhaesebroeck, B;
Bilanges, B;
Madsen, RR;
Dale, KL;
Lau, E;
Vladimirou, E;
(2019)
Perspective: Potential Impact and Therapeutic Implications of Oncogenic PI3K Activation on Chromosomal Instability.
Biomolecules
, 9
(8)
, Article 331. 10.3390/biom9080331.
|
|
|
Vanhaesebroeck, B;
Whitehead, MA;
Pineiro, R;
(2016)
Molecules in medicine mini-review: isoforms of PI3K in biology and disease.
Journal of Molecular Medicine
, 94
(1)
pp. 5-11.
10.1007/s00109-015-1352-5.
|
|
Vargas, FA;
Furness, AJS;
Litchfield, K;
Joshi, K;
Rosenthal, R;
Ghorani, E;
Solomon, I;
... Quezada, SA; + view all
(2018)
Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.
Cancer Cell
, 33
(4)
pp. 649-663.
10.1016/j.ccell.2018.02.010.
|
|
|
Vargas, FA;
Furness, AJS;
Solomon, I;
Joshi, K;
Mekkaoui, L;
Lesko, MH;
Rota, EM;
... Quezada, SA; + view all
(2017)
Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors.
Immunity
, 46
(4)
pp. 577-586.
10.1016/j.immuni.2017.03.013.
|
|
|
Várnai, Csilla;
Palles, Claire;
Arnold, Roland;
Curley, Helen M;
Purshouse, Karin;
Cheng, Vinton WT;
Booth, Stephen;
... Kurec, Bartlomiej; + view all
(2022)
Mortality Among Adults With Cancer Undergoing Chemotherapy or Immunotherapy and Infected With COVID-19.
JAMA Network Open
, 5
(2)
, Article e220130. 10.1001/jamanetworkopen.2022.0130.
|
|
|
Varrault, A;
Dantec, C;
Le Digarcher, A;
Chotard, L;
Bilanges, B;
Parrinello, H;
Dubois, E;
... Journot, L; + view all
(2017)
Identification of Plagl1/Zac1 binding sites and target genes establishes its role in the regulation of extracellular matrix genes and the imprinted gene network.
Nucleic Acids Research
, 45
(18)
pp. 10466-10480.
10.1093/nar/gkx672.
|
|
|
Vassileva, VT;
(2008)
The Effects of Sustained and Intermittent Intraperitoneal Paclitaxel Chemotherapy on Tumour Repopulation and Response in Ovarian Cancer.
Doctoral thesis , University of Toronto.
|
|
Vassileva, VT;
(2003)
Analysis of Genetic Targets Contributing to Mutator Phenotype of Endometrial Cancer.
Masters thesis , University of Toronto.
|
|
Velikova, Galina;
Morden, James P;
Haviland, Joanne S;
Emery, Charlotte;
Barrett-Lee, Peter;
Earl, Helena;
Bloomfield, David;
... Cameron, David; + view all
(2023)
Accelerated versus standard epirubicin followed by cyclophosphamide, methotrexate, and fluorouracil or capecitabine as adjuvant therapy for breast cancer (UK TACT2; CRUK/05/19): quality of life results from a multicentre, phase 3, open-label, randomised, controlled trial.
The Lancet Oncology
10.1016/s1470-2045(23)00460-6.
(In press).
|
|
Vena, F;
(2016)
MEK inhibition in pancreas cancer.
Doctoral thesis , UCL (University College London).
|
|
|
Vena, F;
Jia, R;
Estandian, A;
Garcia-Gomez, JJ;
Rodriguez-Justo, M;
MA, J;
Syed, S;
... Hochhauser, D; + view all
(2018)
MEK inhibition leads to BRCA2 downregulation and sensitization to DNA damaging agents in pancreas and ovarian cancer models.
Oncotarget
, 9
(14)
pp. 11592-11603.
10.18632/oncotarget.24294.
|
|
|
Vendramin, R;
Litchfield, K;
Swanton, C;
(2021)
Cancer evolution: Darwin and beyond.
EMBO Journal
, Article e108389. 10.15252/embj.2021108389.
|
|
|
Venkatesan, S;
Angelova, M;
Bartkova, J;
Bakhoum, SF;
Bartek, J;
Kanu, N;
Swanton, C;
(2021)
APOBEC3 as a driver of genetic intratumor heterogeneity.
Molecular and Cellular Oncology
10.1080/23723556.2021.2014734.
(In press).
|
|
|
Venkatesan, S;
Angelova, M;
Puttick, C;
Zhai, H;
Caswell, DR;
Lu, W-T;
Dietzen, M;
... Consortium, T; + view all
(2021)
Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution.
Cancer Discovery
, 11
(10)
pp. 2456-2473.
10.1158/2159-8290.CD-20-0725.
|
|
Venkatesan, S;
Rosenthal, R;
Kanu, N;
McGranahan, N;
Bartek, J;
Quezada, SA;
Hare, J;
... Swanton, C; + view all
(2018)
APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution.
Annals of Oncology
, 29
(3)
pp. 563-572.
10.1093/annonc/mdy003.
|
|
|
Vergote, I;
Gonzalez-Martin, A;
Lorusso, D;
Gourley, C;
Mirza, MR;
Kurtz, JE;
Okamoto, A;
... Zhu, J; + view all
(2022)
Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup.
The Lancet Oncology
, 23
(8)
e374-e384.
10.1016/S1470-2045(22)00139-5.
|
|
Vesely, Clare;
Wong, Yien Ning Sophia;
Childs, Alexa;
Akarca, Ayse U;
Dhami, Pawan;
Vaikkinen, Heli;
Conde, Lucia;
... Meyer, Tim; + view all
(2022)
Systematic Evaluation of the Immune Environment of Small Intestinal Neuroendocrine Tumours.
Clinical Cancer Research
10.1158/1078-0432.CCR-21-4203.
(In press).
|
|
|
Vesely, C;
Childs, A;
Wong, YNS;
Ogunbiyi, O;
Gander, A;
Luong, T;
Thirlwell, C;
... Meyer, T; + view all
(2018)
Systematic Evaluation of the Immune Microenvironment of Neuroendocrine Tumors (NET).
Presented at: 15th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease, Barcelona, Spain.
|
|
Vicencio, JM;
Evans, R;
Green, R;
An, Z;
Deng, J;
Treacy, C;
Mustapha, R;
... Ng, T; + view all
(2022)
Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans.
Cell Death & Disease
, 13
(3)
, Article 274. 10.1038/s41419-022-04701-3.
|
|
|
Vicencio, JM;
Yellon, DM;
Sivaraman, V;
Das, D;
Boi-Doku, C;
Arjun, S;
Zheng, Y;
... Davidson, SM; + view all
(2015)
Plasma exosomes protect the myocardium from ischemia-reperfusion injury.
Journal of the American College of Cardiology
, 65
(15)
pp. 1525-1536.
10.1016/j.jacc.2015.02.026.
|
|
Vinceti, Alessandro;
De Lucia, Riccardo Roberto;
Cremaschi, Paolo;
Perron, Umberto;
Karakoc, Emre;
Mauri, Luca;
Fernandez, Carlos;
... Iorio, Francesco; + view all
(2023)
An interactive web application for processing, correcting, and visualizing genome-wide pooled CRISPR-Cas9 screens.
Cell Reports Methods
, 3
(1)
, Article 100373. 10.1016/j.crmeth.2022.100373.
|
|
Vogel, Arndt;
Grant, Robert C;
Meyer, Tim;
Sapisochin, Gonzalo;
O'Kane, Grainne M;
Saborowski, Anna;
(2023)
Adjuvant and neoadjuvant therapies for hepatocellular carcinoma.
Hepatology
10.1097/HEP.0000000000000726.
(In press).
|
|
Vogel, Arndt;
Kelley, Robin Kate;
Johnson, Philip;
Merle, Philippe;
Yau, Thomas;
Kudo, Masatoshi;
Meyer, Tim;
(2023)
Predictive and prognostic potential of liver function assessment in patients with advanced hepatocellular carcinoma: a systematic literature review.
Liver Cancer
, 12
(4)
pp. 372-391.
10.1159/000529173.
|
|
Vogel, A;
Cervantes, A;
Chau, I;
Daniele, B;
Llovet, J;
Meyer, T;
Nault, J-C;
... Martinelli, E; + view all
(2018)
Hepatocellular carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Annals of Oncology
, 29
(4)
iv238-iv255.
10.1093/annonc/mdy308.
|
|
|
Vogl, UM;
Beer, TM;
Davis, ID;
Shore, ND;
Sweeney, CJ;
Ost, P;
Attard, G;
... APCCC 2019 expert panel, .; + view all
(2022)
Lack of consensus identifies important areas for future clinical research: Advanced Prostate Cancer Consensus Conference (APCCC) 2019 findings.
European Journal of Cancer
, 160
pp. 24-60.
10.1016/j.ejca.2021.09.036.
|
|
Volpi, D;
Tullis, IDC;
Barber, PR;
Augustyniak, EM;
Smart, SC;
Vallis, KA;
Vojnovic, B;
(2017)
Electrically tunable fluidic lens imaging system for laparoscopic fluorescence-guided surgery.
Biomedical Optics Express
, 8
(7)
pp. 3232-3247.
10.1364/BOE.8.003232.
|
|
|
Volz, E;
Mishra, S;
Chand, M;
Barrett, JC;
Johnson, R;
Geidelberg, L;
Hinsley, WR;
... Ferguson, NM; + view all
(2021)
Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England.
Nature
, 593
(7858)
pp. 266-269.
10.1038/s41586-021-03470-x.
|
|
Vusirikala, A;
Ensor, D;
Asokan, AK;
Lee, AJX;
Ray, R;
Tsekes, D;
Edwin, J;
(2021)
Hello, can you hear me? Orthopaedic clinic telephone consultations in the COVID-19 era- a patient and clinician perspective.
World Journal of Orthopedics
, 12
(1)
pp. 24-34.
10.5312/wjo.v12.i1.24.
|
|
W
|
Wainberg, ZA;
Fuchs, CS;
Tabernero, J;
Shitara, K;
Muro, K;
Van Cutsem, E;
Bang, Y-J;
... Chao, J; + view all
(2021)
Efficacy of Pembrolizumab Monotherapy for Advanced Gastric/Gastroesophageal Junction Cancer with Programmed Death Ligand 1 Combined Positive Score ≥10.
Clinical Cancer Research
, 27
(7)
pp. 1923-1931.
10.1158/1078-0432.CCR-20-2980.
|
|
Waked, I;
Berhane, S;
Toyoda, H;
Chan, SL;
Stern, N;
Palmer, D;
Tada, T;
... Johnson, PJ; + view all
(2017)
Transarterial chemo-embolisation of hepatocellular carcinoma: impact of liver function and vascular invasion.
British Journal of Cancer
, 116
pp. 448-454.
10.1038/bjc.2016.423.
|
|
|
Walker, K;
Hinsley, S;
Phillip, R;
Oughton, JB;
Murden, G;
Chalmers, AJ;
Faivre-Finn, C;
... Young, R; + view all
(2022)
Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations-CONCORDE.
JCO Precision Oncology
, 6
(6)
, Article e2200133. 10.1200/PO.22.00133.
|
|
Wall, EC;
Wu, M;
Harvey, R;
Kelly, G;
Warchal, S;
Sawyer, C;
Daniels, R;
... Bauer, DL; + view all
(2021)
AZD1222-induced neutralising antibody activity against SARS-CoV-2 Delta VOC.
The Lancet
10.1016/S0140-6736(21)01462-8.
(In press).
|
|
|
Wall, EC;
Wu, M;
Harvey, R;
Kelly, G;
Warchal, S;
Sawyer, C;
Daniels, R;
... Bauer, DLV; + view all
(2021)
Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination.
The Lancet
10.1016/s0140-6736(21)01290-3.
(In press).
|
|
|
Walls, GM;
Oughton, JB;
Chalmers, AJ;
Brown, S;
Collinson, F;
Forster, MD;
Franks, KN;
... Greystoke, A; + view all
(2020)
CONCORDE: A phase I platform study of novel agents in combination with conventional radiotherapy in non-small-cell lung cancer.
Clinical and Translational Radiation Oncology
, 25
pp. 61-66.
10.1016/j.ctro.2020.09.006.
|
|
|
Waterhouse, JV;
Hull, JH;
Linch, M;
(2020)
Corticosteroids for Urological Cancer Care During Coronavirus Disease 2019. Treat or Not to Treat?
European Urology
10.1016/j.eururo.2020.04.027.
(In press).
|
|
|
Watkins, Thomas BK;
Colliver, Emma C;
Huska, Matthew R;
Kaufmann, Tom L;
Lim, Emilia L;
Duncan, Cody B;
Haase, Kerstin;
... Schwarz, Roland F; + view all
(2023)
Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity.
PLoS Computational Biology
, 19
(10)
, Article e1011379. 10.1371/journal.pcbi.1011379.
|
|
Watkins, TBK;
Lim, EL;
Petkovic, M;
Elizalde, S;
Birkbak, NJ;
Wilson, GA;
Moore, DA;
... Swanton, C; + view all
(2020)
Pervasive chromosomal instability and karyotype order in tumour evolution.
Nature
, 587
pp. 126-132.
10.1038/s41586-020-2698-6.
|
|
Watt, Eleanor Sinead Igrainne;
(2024)
Immune Reconstitution in Thymus Transplant Patients.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Wedge, DC;
Gundem, G;
Mitchell, T;
Woodcock, DJ;
Martincorena, I;
Ghori, M;
Zamora, J;
... Eeles, RA; + view all
(2018)
Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.
Nature Genetics
, 50
(5)
pp. 682-692.
10.1038/s41588-018-0086-z.
|
|
Weeden, CE;
Gayevskiy, V;
Marceaux, C;
Batey, D;
Tan, T;
Yokote, K;
Ribera, NT;
... Asselin-Labat, ML; + view all
(2023)
Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer.
Cancer Cell
, 41
(5)
837-852.e6.
10.1016/j.ccell.2023.03.019.
|
|
|
Weiner, Adam BB;
Liu, Yang;
Hakansson, Alex;
Zhao, Xin;
Proudfoot, James AA;
Ho, Julian;
Zhang, JJHH;
... Schaeffer, Edward MM; + view all
(2023)
A novel prostate cancer subtyping classifier based on luminal and basal phenotypes.
Cancers
10.1002/cncr.34790.
(In press).
|
|
|
Weitsman, G;
Barber, PR;
Nguyen, LK;
Lawler, K;
Patel, G;
Woodman, N;
Kelleher, MT;
... Ng, T; + view all
(2016)
HER2-HER3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER2 IHC status.
Oncotarget
, 7
(32)
pp. 51012-51026.
10.18632/oncotarget.9963.
|
|
Weitsman, G;
Mitchell, NJ;
Evans, R;
Cheung, A;
Kalber, TL;
Bofinger, R;
Fruhwirth, GO;
... Ng, T; + view all
(2017)
Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor.
Oncogene
, 36
pp. 3618-3628.
10.1038/onc.2016.522.
|
|
|
Wicki, A;
Brown, N;
Xyrafas, A;
Bize, V;
Hawle, H;
Berardi, S;
Cmiljanović, N;
... Kristeleit, R; + view all
(2018)
First-in human, phase 1, dose-escalation pharmacokinetic and pharmacodynamic study of the oral dual PI3K and mTORC1/2 inhibitor PQR309 in patients with advanced solid tumors (SAKK 67/13).
European Journal of Cancer
, 96
pp. 6-16.
10.1016/j.ejca.2018.03.012.
|
|
Wilcz-Villega, E;
Carter, E;
Ironside, A;
Xu, R;
Mataloni, I;
Holdsworth, J;
Jones, W;
... Bianchi, K; + view all
(2020)
Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway.
EMBO Molecular Medicine
, Article e10491. 10.15252/emmm.201910491.
(In press).
|
|
|
Willett, BJ;
Grove, J;
MacLean, OA;
Wilkie, C;
De Lorenzo, G;
Furnon, W;
Cantoni, D;
... Thomson, EC; + view all
(2022)
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway.
Nature Microbiology
10.1038/s41564-022-01143-7.
(In press).
|
|
|
Wilson, GA;
Lechner, M;
Köferle, A;
Carén, H;
Butcher, LM;
Feber, A;
Fenton, T;
... Beck, S; + view all
(2013)
Integrated virus-host methylome analysis in head and neck squamous cell carcinoma.
Epigenetics
, 8
(9)
pp. 953-961.
10.4161/epi.25614.
|
|
|
Windsor, Rachael;
Hamilton, Anthony;
McTiernan, Anne;
Dileo, Palma;
Michelagnoli, Maria;
Seddon, Beatrice;
Strauss, Sandra J;
(2022)
Survival after high-dose chemotherapy for refractory and recurrent Ewing sarcoma.
European Journal of Cancer
, 170
pp. 131-139.
10.1016/j.ejca.2022.04.007.
|
|
Winter, H;
Kaisaki, PJ;
Harvey, J;
Giacopuzzi, E;
Ferla, MP;
Pentony, MM;
Knight, SJL;
... McCullagh, JSO; + view all
(2019)
Identification of Circulating Genomic and Metabolic Biomarkers in Intrahepatic Cholangiocarcinoma.
Cancers
, 11
(12)
, Article 1895. 10.3390/cancers11121895.
|
|
|
Wolf, Y;
Bartok, O;
Patkar, S;
Bar Eli, G;
Cohen, S;
Litchfield, K;
Levy, R;
... Samuels, Y; + view all
(2019)
UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma.
Cell
, 179
(1)
219-235.e21.
10.1016/j.cell.2019.08.032.
|
|
|
Woll, Penella J;
Gaunt, Piers;
Gaskell, Charlotte;
Young, Robin;
Benson, Charlotte;
Judson, Ian R;
Seddon, Beatrice M;
... Billingham, Lucinda; + view all
(2023)
Axitinib in patients with advanced/metastatic soft tissue sarcoma (Axi-STS): an open-label, multicentre, phase II trial in four histological strata.
British Journal of Cancer (BJC)
10.1038/s41416-023-02416-6.
(In press).
|
|
Wong, YNS;
Sng, CCT;
Ottaviani, D;
Patel, G;
Chowdhury, A;
Earnshaw, I;
Sinclair, A;
... Lee, AJX; + view all
(2021)
Systemic anti-cancer therapy and metastatic cancer are independent mortality risk factors during two uk waves of the covid-19 pandemic at university college london hospital.
Cancers
, 13
(23)
, Article 6085. 10.3390/cancers13236085.
|
|
|
Wong, YNS;
Joshi, K;
Khetrapal, P;
Ismail, M;
Reading, JL;
Sunderland, MW;
Georgiou, A;
... Quezada, SA; + view all
(2018)
Urine-derived lymphocytes as a non-invasive measure of the bladder tumor immune microenvironment.
Journal of Experimental Medicine
, 215
(11)
pp. 2748-2759.
10.1084/jem.20181003.
|
|
|
Wong, YNS;
Joshi, K;
Pule, M;
Peggs, KS;
Swanton, C;
Quezada, SA;
Linch, M;
(2017)
Evolving adoptive cellular therapies in urological malignancies.
Lancet Oncology
, 18
(6)
E341-E353.
10.1016/S1470-2045(17)30327-3.
|
|
|
Wood, Georgina E;
Graves, Laurie A;
Rubin, Elyssa M;
Reed, Damon R;
Riedel, Richard F;
Strauss, Sandra J;
(2023)
Bad to the Bone: Emerging Approaches to Aggressive Bone Sarcomas.
American Society of Clinical Oncology Educational Book
, 43
(43)
, Article e390306. 10.1200/EDBK_390306.
|
|
Woodcock, HV;
Eley, JD;
Guillotin, D;
Plate, M;
Nanthakumar, CB;
Martufi, M;
Peace, S;
... Chambers, RC; + view all
(2019)
The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis.
Nature Communications
, 10
, Article 6. 10.1038/s41467-018-07858-8.
|
|
|
Woodcock, HV;
Eley, JD;
Guillotin, D;
Platé, M;
Nanthakumar, CB;
Martufi, M;
Peace, S;
... Chambers, RC; + view all
(2020)
Author Correction: The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis.
[Corrigendum].
Nature Communications
, 11
, Article 4680. 10.1038/s41467-020-18621-3.
|
|
|
Woods, BS;
Sideris, E;
Sydes, MR;
Gannon, MR;
Parmar, MKB;
Alzouebi, M;
Attard, G;
... Sculpher, MJ; + view all
(2018)
Addition of Docetaxel to First-line Long-term Hormone Therapy in Prostate Cancer (STAMPEDE): Modelling to Estimate Long-term Survival, Quality-adjusted Survival, and Cost-effectiveness.
European Urology Oncology
, 1
(6)
pp. 449-458.
10.1016/j.euo.2018.06.004.
|
|
|
Worrall, JT;
Tamura, N;
Mazzagatti, A;
Shaikh, N;
van Lingen, T;
Bakker, B;
Spierings, DCJ;
... McClelland, SE; + view all
(2018)
Non-random Mis-segregation of Human Chromosomes.
Cell Reports
, 23
(11)
pp. 3366-3380.
10.1016/j.celrep.2018.05.047.
|
|
|
Wright, DW;
Harvey, WT;
Hughes, J;
Cox, M;
Peacock, TP;
Colquhoun, R;
Jackson, B;
... Hassan-Ibrahim, MO; + view all
(2022)
Tracking SARS-CoV-2 mutations and variants through the COG-UK-Mutation Explorer.
Virus Evolution
, 8
(1)
, Article veac023. 10.1093/ve/veac023.
|
|
|
Wu, M;
Shen, H;
Wang, Z;
Kanu, N;
Chen, K;
(2022)
Research Progress on Postoperative Minimal/Molecular Residual Disease Detection in Lung Cancer.
Chronic Diseases and Translational Medicine
10.1002/cdt3.10.
|
|
|
Wu, Mary Y;
Carr, Edward J;
Harvey, Ruth;
Mears, Harriet V;
Kjaer, Svend;
Townsley, Hermaleigh;
Hobbs, Agnieszka;
... Bauer, David LV; + view all
(2022)
WHO's Therapeutics and COVID-19 Living Guideline on mAbs needs to be reassessed.
The Lancet
, 400
(10369)
pp. 2193-2196.
10.1016/s0140-6736(22)01938-9.
|
|
Wu, MY;
Shepherd, STC;
Fendler, A;
Carr, EJ;
Au, L;
Harvey, R;
Dowgier, G;
... Turajlic, S; + view all
(2023)
Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer.
Cancer Cell
, 41
(5)
pp. 821-823.
10.1016/j.ccell.2023.04.005.
|
|
|
Wu, Wenyi;
Ma, Gaoen;
Qi, Hui;
Dong, Lijun;
Chen, Fang;
Wang, Yun;
Mao, Xingxing;
... Lei, Hetian; + view all
(2022)
Genome Editing of Pik3cd Impedes Abnormal Retinal Angiogenesis.
Human Gene Therapy
10.1089/hum.2022.079.
(In press).
|
|
Wu, Wenyi;
Ma, Gaoen;
Qi, Hui;
Dong, Lijun;
Chen, Fang;
Wang, Yun;
Mao, Xingxing;
... Lei, Hetian; + view all
(2023)
Correction to: Genome Editing of Pik3cd Impedes Abnormal Retinal Angiogenesis, by Wu et al. Hum Gene Ther 2023;34(1-2):30-41; doi: 10.1089/hum.2022.079.
[Corrigendum].
Human Gene Therapy
, 34
(9-10)
p. 471.
10.1089/hum.2022.079.correx.
|
|
|
Wu, Yin;
Biswas, Dhruva;
Usaite, Ieva;
Angelova, Mihaela;
Boeing, Stefan;
Karasaki, Takahiro;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2022)
A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer.
Nature Cancer
, 3
pp. 696-709.
10.1038/s43018-022-00376-z.
|
|
Wu, A;
Attard, G;
(2019)
Plasma DNA Analysis in Prostate Cancer: Opportunities for Improving Clinical Management.
Clinical Chemistry
, 65
(1)
10.1373/clinchem.2018.287250.
|
|
Wu, A;
Cremaschi, P;
Wetterskog, D;
Conteduca, V;
Franceschini, GM;
Kleftogiannis, D;
Jayaram, A;
... Attard, G; + view all
(2020)
Genome-wide plasma DNA methylation features of metastatic prostate cancer.
Journal of Clinical Investigation
, 130
(4)
pp. 1991-2000.
10.1172/JCI130887.
|
|
|
Wu, C-E;
Esfandiari, A;
Ho, Y-H;
Wang, N;
Mahdi, AK;
Aptullahoglu, E;
Lovat, P;
(2018)
Targeting negative regulation of p53 by MDM2 and WIP1 as a therapeutic strategy in cutaneous melanoma.
British Journal of Cancer
, 118
(4)
pp. 495-508.
10.1038/bjc.2017.433.
|
|
|
Wu, C-E;
Koay, TS;
Esfandiari, A;
Ho, Y-H;
Lovat, P;
Lunec, J;
(2018)
ATM Dependent DUSP6 Modulation of p53 Involved in Synergistic Targeting of MAPK and p53 Pathways with Trametinib and MDM2 Inhibitors in Cutaneous Melanoma.
Cancers
, 11
(1)
, Article 3. 10.3390/cancers11010003.
|
|
|
Wu, W;
Zhou, G;
Han, H;
Huang, X;
Jiang, H;
Mukai, S;
Kazlauskas, A;
... Lei, H; + view all
(2020)
PI3Kδ as a Novel Therapeutic Target in Pathological Angiogenesis.
Diabetes
, 69
(4)
pp. 739-748.
10.2337/db19-0713.
|
|
Wu, Y;
Biswas, D;
Swanton, C;
(2021)
Impact of cancer evolution on immune surveillance and checkpoint inhibitor response.
Seminars in Cancer Biology
10.1016/j.semcancer.2021.02.013.
(In press).
|
|
|
Wulaningsih, W;
Holmberg, L;
Abeler-Doner, L;
Ng, T;
Rohrmann, S;
Van Hemelrijck, M;
(2016)
Associations of C-Reactive Protein, Granulocytes and Granulocyte-to-Lymphocyte Ratio with Mortality from Breast Cancer in Non-Institutionalized American Women.
PLoS ONE
, 11
(6)
, Article e0157482. 10.1371/journal.pone.0157482.
|
|
|
Wulaningsih, W;
Holmberg, L;
Abeler-Dörner, L;
Ng, T;
Rohrmann, S;
Van Hemelrijck, M;
(2017)
Correction: Associations of C-Reactive Protein, Granulocytes and Granulocyte-to-Lymphocyte Ratio with Mortality from Breast Cancer in Non-Institutionalized American Women.
PLoS One
, 11
(8)
, Article e0161418. 10.1371/journal.pone.0161418.
|
|
|
Wulaningsih, W;
Holmberg, L;
Garmo, H;
Karagiannis, SN;
Ahlstedt, S;
Malmstrom, H;
Lambe, M;
... Van Hemelrijck, M; + view all
(2016)
Investigating the association between allergen-specific immunoglobulin E, cancer risk and survival.
Oncoimmunology
, 5
(6)
, Article e1154250. 10.1080/2162402X.2016.1154250.
|
|
|
Wyatt, AW;
Litiere, S;
Bidard, FC;
Cabel, L;
Dyrskjøt, L;
Karlovich, CA;
Pantel, K;
... The RECIST ctDNA workshop group; + view all
(2024)
Plasma ctDNA as a Treatment Response Biomarker in Metastatic Cancers: Evaluation by the RECIST Working Group.
Clinical Cancer Research
, 30
(22)
pp. 5034-5041.
10.1158/1078-0432.CCR-24-1883.
|
X
|
Xu, R;
Jones, W;
Wilcz-Villega, E;
Costa, AS;
Rajeeve, V;
Bentham, RB;
Bryson, K;
... Bianchi, K; + view all
(2020)
The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism.
EMBO Reports
, Article e48260. 10.15252/embr.201948260.
|
|
Y
|
Yi, W;
Stavrinides, V;
Baum, ZMC;
Yang, Q;
Barratt, DC;
Clarkson, MJ;
Hu, Y;
(2023)
Boundary-RL: Reinforcement Learning for Weakly-Supervised Prostate Segmentation in TRUS Images.
In: Cao, Xiaohuan and Xu, Xuanang and Rekik, Islem and Cui, Zhiming and Ouyang, Xi, (eds.)
Machine Learning in Medical Imaging.
(pp. pp. 277-288).
Springer Nature: Cham, Switzerland.
|
|
Yngvadottir, Bryndis;
Andreou, Avgi;
Bassaganyas, Laia;
Larionov, Alexey;
Cornish, Alex J;
Chubb, Daniel;
Saunders, Charlie N;
... Maher, Eamonn R; + view all
(2022)
Frequency of pathogenic germline variants in cancer susceptibility genes in 1336 renal cell carcinoma cases.
Human Molecular Genetics
, Article ddac089. 10.1093/hmg/ddac089.
(In press).
|
|
Yoshida, K;
Gowers, KHC;
Lee-Six, H;
Chandrasekharan, DP;
Coorens, T;
Maughan, EF;
Beal, K;
... Campbell, PJ; + view all
(2020)
Tobacco smoking and somatic mutations in human bronchial epithelium.
Nature
, 578
pp. 266-272.
10.1038/s41586-020-1961-1.
|
|
Younger, E;
Smrke, A;
Lidington, E;
Farag, S;
Ingley, K;
Chopra, N;
Maleddu, A;
... Jones, RL; + view all
(2020)
Health-Related Quality of Life and Experiences of Sarcoma Patients during the COVID-19 Pandemic.
Cancers
, 12
(8)
, Article 2288. 10.3390/cancers12082288.
|
|
|
Yousefi, Maryam;
Boross, Gábor;
Weiss, Carly;
Murray, Christopher W;
Hebert, Jess D;
Cai, Hongchen;
Ashkin, Emily L;
... Winslow, Monte M; + view all
(2022)
Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities.
Cancer Research
, 82
(8)
pp. 1589-1602.
10.1158/0008-5472.CAN-22-0059.
|
Z
|
Zachara, Magda;
Rainer, Pernille Y;
Hashimi, Horia;
Russeil, Julie M;
Alpern, Daniel;
Ferrero, Radiana;
Litovchenko, Maria;
(2022)
Mammalian adipogenesis regulator (Areg) cells use retinoic acid signalling to be non- and anti-adipogenic in age-dependent manner.
The EMBO Journal
, Article e108206. 10.15252/embj.2021108206.
(In press).
|
|
Zalmas, Lykourgos-Panagiotis;
Lu, Wei-Ting;
Kanu, Nnennaya;
(2019)
An emerging regulatory network of NHEJ via DYNLL1-mediated 53BP1 redistribution.
Annals of Translational Medicine
, 7
(Suppl 3)
, Article S93. 10.21037/atm.2019.04.39.
|
|
|
Zamborszky, J;
Szikriszt, B;
Gervai, JZ;
Pipek, O;
Poti, A;
Krzystanek, M;
Ribli, D;
... Szuets, D; + view all
(2016)
Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions.
Oncogene
, 36
(6)
pp. 746-755.
10.1038/onc.2016.243.
|
|
|
Zammarchi, Francesca;
Havenith, Karin E;
Sachini, Nikoleta;
Janghra, Narinder;
Chivers, Simon;
Idusogie, Esohe;
Gaudio, Eugenio;
... Van Berkel, Patrick H; + view all
(2024)
ADCT-602, a Novel PBD Dimer–containing Antibody–Drug Conjugate for Treating CD22-positive Hematologic Malignancies.
Molecular Cancer Therapeutics
OF1-OF12.
10.1158/1535-7163.MCT-23-0506.
(In press).
|
|
|
Zammarchi, Francesca;
Havenith, Karin Eg;
Chivers, Simon;
Hogg, Paul;
Bertelli, Francois;
Tyrer, Peter;
Janghra, Narinder;
... van Berkel, Patrick H; + view all
(2022)
Preclinical Development of ADCT-601, a Novel Pyrrolobenzodiazepine Dimer-based Antibody-drug Conjugate Targeting AXL-expressing Cancers.
Molecular Cancer Therapeutics
, 21
(4)
pp. 582-593.
10.1158/1535-7163.MCT-21-0715.
|
|
|
Zammarchi, F;
Corbett, S;
Adams, L;
Tyrer, PC;
Kiakos, K;
Janghra, N;
Marafioti, T;
... van Berkel, PH; + view all
(2018)
ADCT-402, a PBD dimer-containing antibody drug conjugate targeting CD19-expressing malignancies.
Blood
, 131
(10)
pp. 1094-1105.
10.1182/blood-2017-10-813493.
|
|
Zhabyeyev, P;
Chen, X;
Vanhaesebroeck, B;
Oudit, GY;
(2019)
PI3Kα in cardioprotection: Cytoskeleton, late Na+ current, and mechanism of arrhythmias.
Channels
, 13
(1)
pp. 520-532.
10.1080/19336950.2019.1697127.
|
|
|
Zhabyeyev, P;
McLean, B;
Chen, X;
Vanhaesebroeck, B;
Oudit, GY;
(2019)
Inhibition of PI3Kinase-α is pro-arrhythmic and associated with enhanced late Na⁺ current, contractility, and Ca²⁺ release in murine hearts.
Journal of Molecular and Cellular Cardiology
, 132
pp. 98-109.
10.1016/j.yjmcc.2019.05.008.
|
|
Zhai, H;
Moore, D;
Jamal-Hanjani, M;
(2020)
Inactivation of RB1 and histological transformation in EGFR-mutant lung adenocarcinoma.
Annals of Oncology
, 31
(2)
pp. 169-170.
10.1016/j.annonc.2019.12.004.
|
|
Zhang, H;
AbdulJabbar, K;
Grunewald, T;
Akarca, A;
Hagos, Y;
Lecat, C;
Pate, D;
... Yuan, Y; + view all
(2022)
Self-supervised Antigen Detection Artificial Intelligence (SANDI).
In: Xu, X and Li, X and Mahapatra, D and Cheng, L and Petitjean, C and Fu, H, (eds.)
Resource-Efficient Medical Image Analysis: First MICCAI Workshop, REMIA 2022, Singapore, September 22, 2022, Proceedings.
(pp. pp. 12-21).
Springer: Cham, Switzerland.
|
|
Zhang, H;
AbdulJabbar, K;
Grunewald, T;
Akarca, AU;
Hagos, Y;
Sobhani, F;
Lecat, CSY;
... Yuan, Y; + view all
(2023)
Self-supervised deep learning for highly efficient spatial immunophenotyping.
eBioMedicine
, 95
, Article 104769. 10.1016/j.ebiom.2023.104769.
|
|
Zhang, Hanyun;
AbdulJabbar, Khalid;
Moore, David A;
Akarca, Ayse;
Enfield, Katey SS;
Jamal-Hanjani, Mariam;
Raza, Shan E Ahmed;
... Yuan, Yinyin; + view all
(2023)
Spatial Positioning of Immune Hotspots Reflects the Interplay between B and T Cells in Lung Squamous Cell Carcinoma.
Cancer Research
, 83
(9)
pp. 1410-1425.
10.1158/0008-5472.CAN-22-2589.
|
|
|
Zhang, Hanyun;
Grunewald, Tami;
Akarca, Ayse U;
Ledermann, Jonathan A;
Marafioti, Teresa;
Yuan, Yinyin;
(2021)
Symmetric Dense Inception Network for Simultaneous Cell
Detection and Classification in Multiplex Immunohistochemistry Images.
In: Atzori, Manfredo and Burlutskiy, Nikolay and Ciompi, Francesco and Li, Zhang and Minhas, Fayyaz and Müller, Henning and Peng, Tingying and Rajpoot, Nasir and Torben_Nielsen, Ben and van der Laak, Jeroen and Veta, Mitko and Yuan, Yinyin and Zlobec, Inti, (eds.)
Proceedings of the MICCAI Workshop on Computational Pathology.
(pp. pp. 246-257).
PMLR
|
|
Zhang, T;
Penicud, K;
Bruhn, C;
Loizou, JI;
Kanu, N;
Wang, ZQ;
Behrens, A;
(2012)
Competition between NBS1 and ATMIN Controls ATM Signaling Pathway Choice.
Cell Reports
, 2
(6)
pp. 1498-1504.
10.1016/j.celrep.2012.11.002.
|
|
|
Zhang, M;
Luo, J-L;
Sun, Q;
Harber, J;
Dawson, AG;
Nakas, A;
Busacca, S;
... Fennell, DA; + view all
(2021)
Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment.
Nature Communications
, 12
(1)
, Article 1751. 10.1038/s41467-021-21798-w.
|
|
|
Zhang, R;
Fruhwirth, GO;
Coban, O;
Barrett, JE;
Burgoyne, T;
Lee, SH;
Simonson, PD;
... Selvin, PR; + view all
(2016)
Probing the Heterogeneity of Protein Kinase Activation in Cells by Super-Resolution Microscopy.
ACS Nano
, 11
(1)
pp. 249-257.
10.1021/acsnano.6b05356.
|
|
Zhao, Y;
Fu, X;
Lopez, JI;
Rowan, A;
Au, L;
Fendler, A;
Hazell, S;
... Litchfield, K; + view all
(2021)
Selection of metastasis competent subclones in the tumour interior.
Nature Ecology & Evolution
, 5
pp. 1033-1045.
10.1038/s41559-021-01456-6.
|
|
|
Zhao, Y;
Morka, N;
Simpson, BSS;
Freeman, A;
Kirkham, A;
Kelly, D;
Whitaker, HC;
... Norris, JM; + view all
(2021)
Prostate-specific membrane antigen positron emission tomography compared to multiparametric MRI for prostate cancer diagnosis: a protocol for a systematic review and meta-analysis.
BMJ Open
, 11
(12)
, Article e052277. 10.1136/bmjopen-2021-052277.
|
|
|
Zhao, Yi;
Simpson, Benjamin S;
Morka, Naomi;
Freeman, Alex;
Kirkham, Alex;
Kelly, Daniel;
Whitaker, Hayley C;
... Norris, Joseph M; + view all
(2022)
Comparison of Multiparametric Magnetic Resonance Imaging with Prostate-Specific Membrane Antigen Positron-Emission Tomography Imaging in Primary Prostate Cancer Diagnosis: A Systematic Review and Meta-Analysis.
Cancers
, 14
(14)
, Article 3497. 10.3390/cancers14143497.
|
|
|
Zhu, Tianyu;
Liu, Jacklyn;
Beck, Stephan;
Pan, Sun;
Capper, David;
Lechner, Matt;
Thirlwell, Chrissie;
... Teschendorff, Andrew E; + view all
(2022)
A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution.
Nature Methods
, 19
pp. 296-306.
10.1038/s41592-022-01412-7.
|
|
Ziff, Oliver J;
Neeves, Jacob;
Mitchell, Jamie;
Tyzack, Giulia;
Martinez-Ruiz, Carlos;
Luisier, Raphaelle;
Chakrabarti, Anob M;
... Patani, Rickie; + view all
(2023)
Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology.
Nature Communications
, 14
, Article 2176. 10.1038/s41467-023-37630-6.
|
|
Zoumpoulidou, G;
Alvarez-Mendoza, C;
Mancusi, C;
Ahmed, R-M;
Denman, M;
Steele, CD;
Tarabichi, M;
... Mittnacht, S; + view all
(2021)
Therapeutic vulnerability to PARP1,2 inhibition in RB1-mutant osteosarcoma.
Nature Communications
, 12
(1)
, Article 7064. 10.1038/s41467-021-27291-8.
|
|
|
Zubairi, I;
Dean, E;
Molife, LR;
Lopez, J;
Ranson, M;
El-Khouly, F;
Savulsky, C;
... Evans, TRJ; + view all
(2016)
Phase 1 multicenter, open-label study to establish the maximum tolerated dose (MTD) of two administration schedules of E7389 (eribulin) liposomal formulation in patients (pts) with solid tumors.
Presented at: 2016 Jahrestagung der DGHO, OeGHO, SGMO und SGH, Leipzig, Germany.
|
