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Number of items: 29.


Bernareggi, A; Conte, G; Constanti, A; Borelli, V; Vita, F; Zabucchi, G; (2019) On the mechanism of the electrophysiological changes and membrane lesions induced by asbestos fiber exposure in Xenopus laevis oocytes. Scientific Reports , 9 , Article 2014. 10.1038/s41598-019-38591-x. Green open access

Borella, E; Oosterholt, S; Magni, P; Pasqua, OD; (2019) Use of prior knowledge and extrapolation in paediatric drug development: A case study with deferasirox. European Journal of Pharmaceutical Sciences 10.1016/j.ejps.2019.05.009. (In press).


Chiou, T-T; Long, P; Schumann-Gillett, A; Kanamarlapudi, K; Haas, SA; Harvey, K; O’Mara, ML; ... Harvey, RJ; + view all (2019) Mutation p.R356Q in the Collybistin Phosphoinositide Binding Site Is Associated With Mild Intellectual Disability. Frontiers in Molecular Neuroscience , 12 , Article 60. 10.3389/fnmol.2019.00060. Green open access

Clout, AE; Della Pasqua, O; Hanna, MG; Orlu, M; Pitceathly, RDS; (2019) Drug repurposing in neurological diseases: an integrated approach to reduce trial and error. Journal of Neurology, Neurosurgery and Psychiatry (In press).


D'Agate, S; Wilson, T; Adalig, B; Manyak, M; Palacios-Moreno, JM; Chavan, C; Oelke, M; ... Della Pasqua, O; + view all (2019) Impact of disease progression on individual IPSS trajectories and consequences of immediate versus delayed start of treatment in patients with moderate or severe LUTS associated with BPH. World Journal of Urology 10.1007/s00345-019-02783-x. (In press). Green open access

De Caro, C; Leo, A; Nesci, V; Ghelardini, C; di Cesare Mannelli, L; Striano, P; Avagliano, C; ... Russo, E; + view all (2019) Intestinal inflammation increases convulsant activity and reduces antiepileptic drug efficacy in a mouse model of epilepsy. Scientific Reports , 9 , Article 13983. 10.1038/s41598-019-50542-0. Green open access

De Leeuw, TG; Mangiarini, L; Lundin, R; Kaguelidou, F; Van Der Zanden, T; Della Pasqua, O; Tibboel, D; ... De Wildt, SN; + view all (2019) Correction to: Gabapentin as add-on to morphine for severe neuropathic or mixed pain in children from age 3 months to 18 years - evaluation of the safety, pharmacokinetics, and efficacy of a new gabapentin liquid formulation: study protocol for a randomized controlled trial. [Corrigendum]. Trials , 20 , Article 368. 10.1186/s13063-019-3519-9. Green open access

De Leeuw, TG; Mangiarini, L; Lundin, R; Kaguelidou, F; Van der Zanden, T; Della Pasqua, O; Tibboel, D; ... GAPP consortium, ; + view all (2019) Gabapentin as add-on to morphine for severe neuropathic or mixed pain in children from age 3 months to 18 years - evaluation of the safety, pharmacokinetics, and efficacy of a new gabapentin liquid formulation: study protocol for a randomized controlled trial. Trials , 20 , Article 49. 10.1186/s13063-018-3169-3. Green open access


Glaze, DG; Neul, JL; Kaufmann, WE; Berry-Kravis, E; Condon, S; Stoms, G; Oosterholt, S; ... Percy, AK; + view all (2019) Double-Blind, Randomized, Placebo-Controlled Study of Trofinetide in Pediatric Rett Syndrome. Neurology , 92 (16) e1912-e1925. 10.1212/WNL.0000000000007316. Green open access

Granno, S; Nixon-Abell, J; Berwick, DC; Tosh, J; Heaton, G; Almudimeegh, S; Nagda, Z; ... Harvey, K; + view all (2019) Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus. Scientific Reports , 9 (1) , Article 7322. 10.1038/s41598-019-43820-4. Green open access


Harvey, K; Outeiro, TF; (2019) The role of LRRK2 in cell signalling. Biochemical Society Transactions , 47 (1) pp. 197-207. 10.1042/BST20180464.


Kaguelidou, F; Le Roux, E; Mangiarini, L; Lundin, R; de Leeuw, TG; Della Pasqua, O; Felisi, M; ... GAPP consortium, .; + view all (2019) Non-inferiority double-blind randomised controlled trial comparing gabapentin versus tramadol for the treatment of chronic neuropathic or mixed pain in children and adolescents: the GABA-1 trial-a study protocol. BMJ Open , 9 (2) , Article e023296. 10.1136/bmjopen-2018-023296. Green open access

Kayal, C; Shipley, RJ; Phillips, JB; (2019) Physical and mechanical properties of RAFT-stabilised collagen gels for tissue engineering applications. Journal of the Mechanical Behavior of Biomedical Materials , 99 pp. 216-224. 10.1016/j.jmbbm.2019.07.011. (In press).

Kloprogge, F; Hammond, R; Copas, A; Gillespie, SH; Della Pasqua, O; (2019) Can phenotypic data complement our understanding of antimycobacterial effects for drug combinations? Journal of Antimicrobial Chemotherapy 10.1093/jac/dkz369. (In press). Green open access


Lambert, JRA; Howe, SJ; Rahim, AA; Burke, DG; Heales, SJR; (2019) Inhibition of Mitochondrial Complex I Impairs Release of α-Galactosidase by Jurkat Cells. International Journal of Molecular Sciences , 20 (18) , Article 4349. 10.3390/ijms20184349. Green open access

Leo, A; De Caro, C; Nesci, V; Palma, E; Tallarico, M; Iannone, M; Constanti, A; ... Citraro, R; + view all (2019) Antiepileptogenic effects of Ethosuximide and Levetiracetam in WAG/Rij rats are only temporary. Pharmacological Reports , 71 (5) pp. 833-838. 10.1016/j.pharep.2019.04.017.


Medawar, E; Benway, TA; Liu, W; Hanan, TA; Haslehurst, P; James, OT; Yap, K; ... Edwards, FA; + view all (2019) Effects of rising amyloidβ levels on hippocampal synaptic transmission, microglial response and cognition in APPSwe/PSEN1M146V transgenic mice. EBioMedicine 10.1016/j.ebiom.2018.12.006. (In press). Green open access


Outeiro, TF; Harvey, K; Dominguez-Meijide, A; Gerhardt, E; (2019) LRRK2, alpha-synuclein, and tau: partners in crime or unfortunate bystanders? Biochemical Society Transactions 10.1042/BST20180466. (In press).


Petrache, AL; Rajulawalla, A; Shi, A; Wetzel, A; Saito, T; Saido, TC; Harvey, K; (2019) Aberrant Excitatory–Inhibitory Synaptic Mechanisms in Entorhinal Cortex Microcircuits During the Pathogenesis of Alzheimer’s Disease. Cerebral Cortex , 29 (4) pp. 1834-1850. 10.1093/cercor/bhz016. Green open access


Santiago-Toledo, G; Georgiou, M; Dos Reis, J; Roberton, VH; Valinhas, A; Wood, RC; Phillips, JB; ... Wall, IB; + view all (2019) Generation of c-MycERTAM-transduced human late-adherent olfactory mucosa cells for potential regenerative applications. Scientific Reports , 9 (1) , Article 13190. 10.1038/s41598-019-49315-6. Green open access

Shah, MM; Martinello, K; Giacalone, E; Migliore, M; Brown, D; (2019) The subthreshold-active KV7 current regulates neurotransmission by limiting spike-induced Ca2+ influx in hippocampal mossy fiber synaptic terminals. Communications Biology , 2 , Article 145. 10.1038/s42003-019-0408-4. Green open access

Shi, A; Petrache, AL; Shi, J; Ali, A; (2019) Preserved Calretinin interneurons in an app model of Alzheimer’s Disease disrupts hippocampal inhibition via up-regulated P2Y1 purinoreceptors. Cerebral Cortex 10.1093/cercor/bhz165. (In press). Green open access

Snowball, A; Chabrol, E; Wykes, RC; Shekh-Ahmad, T; Cornford, JH; Lieb, A; Hughes, MP; ... Schorge, S; + view all (2019) Epilepsy gene therapy using an engineered potassium channel. Journal of Neuroscience 10.1523/JNEUROSCI.1143-18.2019. (In press). Green open access


Tchorek-Bentall, M; Ruiz, YO; Oosterholt, S; Marks, DJ; Pasqua, OD; (2019) Model-based optimisation of N-acetylcysteine for the treatment of paracetamol overdose. Presented at: British-Pharmacology-Society Meeting (Pharmacology), London, UK.

Topczewska, A; Evans, T; Pratt, W; Burgess, N; Dolphin, A; Shah, M; (2019) T-Type Ca2+ Channels and Layer II Medial Entorhinal Cortical Stellate Cell Excitability. Presented at: American Biophysics Society Annual Meeting 2019, Baltimore, MD, USA.


Vangoor, VR; Reschke, CR; Senthilkumar, K; Van de Haar, LL; De Wit, M; Giuliani, G; Broekhoven, MH; ... Pasterkamp, RJ; + view all (2019) Antagonizing increased miR-135a levels at the chronic stage of experimental TLE reduces spontaneous recurrent seizures. The Journal of Neuroscience 10.1523/JNEUROSCI.3014-18.2019. (In press).

van Dijkman, SC; De Cock, PAJG; Smets, K; Decaluwe, W; Smits, A; Allegaert, K; Vande Walle, J; ... Della Pasqua, O; + view all (2019) Dose rationale and pharmacokinetics of dexmedetomidine in mechanically ventilated new-borns: impact of design optimisation. European Journal of Clinical Pharmacology 10.1007/s00228-019-02708-y. (In press). Green open access


Weston, M; Kaserer, T; Wu, A; Mouravlev, A; Carpenter, JC; Snowball, A; Knauss, S; ... Lieb, A; + view all (2019) Olanzapine: A potent agonist at the hM4D(Gi) DREADD amenable to clinical translation of chemogenetics. Science Advances , 5 (4) , Article eaaw1567. 10.1126/sciadv.aaw1567. Green open access

Wicox, M; Quick, TJ; Phillips, JB; (2019) The Effects of Surgical Antiseptics and Time Delays on RNA Isolated From Human and Rodent Peripheral Nerves. Frontiers in Cellular Neuroscience , 13 , Article 189. 10.3389/fncel.2019.00189. Green open access

This list was generated on Wed Oct 16 21:14:01 2019 BST.