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Number of items: 57.


Allocco, AA; Jin, SC; Duy, PQ; Furey, CG; Zeng, X; Dong, W; Nelson-Williams, C; ... Kahle, KT; + view all (2019) Recessive Inheritance of Congenital Hydrocephalus With Other Structural Brain Abnormalities Caused by Compound Heterozygous Mutations in ATP1A3. Frontiers in Cellular Neuroscience , 13 , Article 425. 10.3389/fncel.2019.00425. Green open access

Asquith, C; laitinen, T; Konstantinova, L; Tizzard, G; Poso, A; Rakitin, O; Hofmann-Lehmann, R; (2019) Investigation of the pentathiepin functionality as an inhibitor of Feline Immunodeficiency Virus (FIV) via a potential zinc ejection mechanism, as a model for HIV infection. ChemMedChem 10.1002/cmdc.201800718. (In press). Green open access

Asquith, CRM; Konstantinova, LS; Tizzard, GJ; Laitinen, T; Coles, SJ; Rakitin, OA; Hilton, ST; (2019) Exploration and Development of a C–H-Activated Route to Access the [1,2]Dithiolo[4,3-b]indole-3(4H)-thione Core and Related Derivatives. Synlett , 30 (2) pp. 156-160. 10.1055/s-0037-1611692. Green open access

Asquith, CRM; Sil, BC; Laitinen, T; Tizzard, GJ; Coles, SJ; Poso, A; Hofmann-Lehmann, R; (2019) Novel epidithiodiketopiperazines as anti-viral zinc ejectors of the Feline Immunodeficiency Virus (FIV) nucleocapsid protein as a model for HIV infection. Bioorganic & Medicinal Chemistry , 27 (18) pp. 4174-4184. 10.1016/j.bmc.2019.07.047.


Bhamra, SK; Slater, A; Howard, C; Heinrich, M; Johnson, MRD; (2019) Health care professionals' personal and professional views of herbal medicines in the United Kingdom. Phytotherapy Research 10.1002/ptr.6418. (In press).

Booker, A; Chatzinasiou, L; Heinrich, M; MacLennan, E; Mackonochie, M; (2019) Turmeric (Curcuma longa L.) products: What quality differences exist? Journal of Herbal Medicine 10.1016/j.hermed.2019.100281. (In press).

Breen, A; Wells, G; Turyanska, L; Bradshaw, T; (2019) Development of novel apoferritin formulations for antitumour benzothiazoles. Cancer Reports , Article e1155. 10.1002/cnr2.1155. (In press). Green open access

Breen, AF; Scurr, D; Cassioli, ML; Wells, G; Thomas, NR; Zhang, J; Turyanska, L; (2019) Protein Encapsulation of Experimental Anticancer Agents 5F 203 and Phortress: Towards Precision Drug Delivery. International Journal of Nanomedicine , 14 pp. 9525-9534. 10.2147/IJN.S226293. Green open access

Brown, P; Tan, A-C; El-Esawi, MA; Liehr, T; Blanck, O; Gladue, DP; Almeida, GMF; ... Zhou, Y; + view all (2019) Large expert-curated database for benchmarking document similarity detection in biomedical literature search. Database 10.1093/database/baz085. (In press). Green open access

Bunc, M; Hanning, SM; Prieto Garcia, J; Kristl, J; Orlu, M; (2019) Characterisation of an in vitro aged cell culture model. Farmacia , 67 (2) pp. 240-247. 10.31925/farmacia.2019.2.7. Green open access


Cuadrado, A; Rojo, A; Wells, G; Hayes, J; Cousin, S; Rumsey, W; Attucks, O; ... Dinkova-Kostova, A; + view all (2019) Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases. Nature Reviews Drug Discovery , 18 pp. 295-317. 10.1038/s41573-018-0008-x. Green open access


Dodoo, CC; Alomari, M; Basit, AW; Stapleton, P; Gaisford, S; (2019) A thermal ink-jet printing approach for evaluating susceptibility of bacteria to antibiotics. Journal of Microbiological Methods , Article 105660. 10.1016/j.mimet.2019.105660. (In press).

Dodoo, CC; Stapleton, P; Basit, AW; Gaisford, S; (2019) Use of a water-based probiotic to treat common gut pathogens. International Journal of Pharmaceutics , 556 pp. 136-141. 10.1016/j.ijpharm.2018.11.075. Green open access

Duran, D; Zeng, X; Jin, SC; Choi, J; Nelson-Williams, C; Yatsula, B; Gaillard, J; ... Kahle, KT; + view all (2019) Mutations in Chromatin Modifier and Ephrin Signaling Genes in Vein of Galen Malformation. Neuron , 101 10.1016/j.neuron.2018.11.041. Green open access


Ferguson, L; Wells, G; Bhakta, S; Johnson, J; Guzman, J; Parish, T; Prentice, RA; (2019) Integrated target-based and phenotypic screening approaches for the identification of anti-tubercular agents that bind to the mycobacterial adenylating enzyme MbtA. ChemMedChem 10.1002/cmdc.201900217. (In press).

Frommenwiler, DA; Booker, A; Vila, R; Heinrich, M; Reich, E; Cañigueral, S; (2019) Comprehensive HPTLC fingerprinting as a tool for a simplified analysis of purity of ginkgo products. Journal of Ethnopharmacology , Article 112084. 10.1016/j.jep.2019.112084.


Guneri, D; Voegeli, R; Munday, MR; Rawlings, AV; (2019) 12R-lipoxygenase activity is reduced in photodamaged facial stratum corneum. A novel activity assay indicates a key function in corneocyte maturation. International Journal of Cosmetic Science , 41 (3) pp. 274-280. 10.1111/ics.12532. Green open access

Guneri, D; Voegeli, R; Zhang, C; Bankousli, A; Munday, M; Lane, M; Rawlings, A; (2019) Humidity-dependent ex vivo corneocyte maturation and the importance of transglutaminase and 12R-lipoxygenase activities. Presented at: Society-for-Investigative-Dermatology (SID) Meeting, Chicago, IL, USA.

Guneri, D; Voegeli, R; Zhang, C; Bankousli, AL; Munday, MR; Rawlings, AV; (2019) The importance of 12R-lipoxygenase and transglutaminase activities in the hydration-dependent ex vivo maturation of corneocyte envelopes. International Journal of Cosmetic Science , 41 pp. 563-578. 10.1111/ics.12574. Green open access


Heinrich, M; Appendino, G; Efferth, T; Fürst, R; Izzo, AA; Kayser, O; Pezzuto, JM; (2019) Best practice in research – Overcoming common challenges in phytopharmacological research. Journal of Ethnopharmacology 10.1016/j.jep.2019.112230. (In press).

Heinrich, M; Hesketh, A; (2019) 25 Years After the `rio Convention'--lessons Learned in the Context of Sustainable Development and Protecting Indigenous and Local Knowledge. Phytomedicine , 53 pp. 332-343. 10.1016/j.phymed.2018.04.061. Green open access

Heinrich, M; Scotti, F; Booker, A; Fitzgerald, M; Kum, KY; Löbel, K; (2019) Unblocking High-Value Botanical Value Chains: Is There a Role for Blockchain Systems? Frontiers in Pharmacology , 10 , Article 396. 10.3389/fphar.2019.00396. Green open access

Hilton, ST; Kozielski, F; Penny, M; Talapatra, S; (2019) Design, 3D printing and validation of a novel low-cost high-capacity sitting-drop bridge for protein crystallization. Journal of Applied Crystallography , 52 pp. 171-174. 10.1107/S1600576718017545. Green open access

Hobson, NJ; Weng, X; Ashford, M; Thanh, NTK; Schätzlein, AG; Uchegbu, IF; (2019) Facile aqueous, room temperature preparation of high transverse relaxivity clustered iron oxide nanoparticles. Colloids and Surfaces A: Physicochemical and Engineering Aspects , 570 pp. 165-171. 10.1016/j.colsurfa.2019.03.023. Green open access

Hobson, NJ; Weng, X; Siow, B; Veiga, C; Ashford, M; Thanh, NT; Schätzlein, AG; (2019) Clustering superparamagnetic iron oxide nanoparticles produces organ-targeted high-contrast magnetic resonance images. Nanomedicine , 14 (9) pp. 1135-1152. 10.2217/nnm-2018-0370. Green open access


Indorato, R-L; Talapatra, SK; Lin, F; Haider, S; Mackay, SP; Kozielski, F; Skoufias, DA; (2019) Is the fate of clinical candidate Arry-520 already sealed? Predicting resistance in Eg5-inhibitor complexes. Molecular Cancer Therapeutics 10.1158/1535-7163.MCT-19-0154. (In press).


Klug, DM; Diaz-Gonzalez, R; Pérez-Moreno, G; Ceballos-Pérez, G; García-Hernández, R; Gomez-Pérez, V; Ruiz-Pérez, LM; ... Pollastri, MP; + view all (2019) Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents. PLoS Neglected Tropical Diseases , 13 (2) , Article e0007129. 10.1371/journal.pntd.0007129. Green open access

Kwapong, AA; Stapleton, P; Gibbons, S; (2019) Inhibiting plasmid mobility: the effect of isothiocyanates on bacterial conjugation. International Journal of Antimicrobial Agents 10.1016/j.ijantimicag.2019.01.011. (In press). Green open access


Lane, M; Sil, B; Hilton, S; Hadgraft, J; Patel, A; Crowther, J; Moore, D; (2019) A Preliminary Investigation of Additive Manufacture to Fabricate Human Nail Plate Surrogates for Pharmaceutical Testing. Pharmaceutics , 11 (6) , Article 250. 10.3390/pharmaceutics11060250. Green open access

Lazarou, R; Heinrich, M; (2019) Herbal Medicine: Who Cares? The changing views on medicinal plants and their roles in British lifestyle. Phytotherapy Research , 33 (9) pp. 2409-2420. 10.1002/ptr.6431.

Li, H; Zhang, Z; Godakanda, VU; Chiu, Y-J; Angkawinitwong, U; Patel, K; Stapleton, PG; ... Williams, GR; + view all (2019) The effect of collection substrate on electrospun ciprofloxacin-loaded poly(vinylpyrrolidone) and ethyl cellulose nanofibers as potential wound dressing materials. Materials Science and Engineering: C , Article 109917. 10.1016/j.msec.2019.109917. (In press).


Mack, AR; Barnes, MD; Taracila, MA; Hujer, AM; Hujer, KM; Cabot, G; Feldgarden, M; ... Bonomo, RA; + view all (2019) A standard numbering scheme for class C β-lactamases. Antimicrobial Agents and Chemotherapy 10.1128/AAC.01841-19. (In press). Green open access

Mackonochie, M; Heinrich, M; (2019) Materia medica chests: investigating the 19th century use of botanicals by different medical professions. Journal of Herbal Medicine 10.1016/j.hermed.2019.100255. (In press). Green open access

Maitra, A; Munshi, T; Healy, J; Martin, LT; Vollmer, W; Keep, NH; Bhakta, S; (2019) Cell wall peptidoglycan in Mycobacterium tuberculosis: An Achilles' heel for the TB-causing pathogen. FEMS Microbiology Reviews , 43 (5) pp. 548-575. 10.1093/femsre/fuz016. Green open access

Manukyan, A; Lumlerdkij, N; Heinrich, M; (2019) Caucasian endemic medicinal and nutraceutical plants: In vitro antioxidant and cytotoxic activities and bioactive compounds. Journal of Pharmacy and Pharmacology , 71 (7) pp. 1152-1161. 10.1111/jphp.13093.

Moore, BJR; Islam, B; Ward, S; Jackson, O; Armitage, R; Blackburn, J; Haider, S; (2019) Repurposing of Tranilast for Potential Neuropathic Pain Treatment by Inhibition of Sepiapterin Reductase in the BH₄ Pathway. ACS Omega , 4 (7) pp. 11960-11972. 10.1021/acsomega.9b01228. Green open access

Moore, M; Trill, J; Simpson, C; Webley, F; Radford, M; Stanton, L; Maishman, T; ... Griffiths, G; + view all (2019) Uva-ursi extract and ibuprofen as alternative treatments for uncomplicated urinary tract infection in women (ATAFUTI): a factorial randomized trial. Clinical Microbiology and Infection 10.1016/j.cmi.2019.01.011. (In press). Green open access


Oyedemi, BO; Maria, KE; Stapleton, PD; Gibbons, S; (2019) Capsaicin and gingerol analogues inhibit the growth of efflux-multidrug resistant bacteria and R-plasmids conjugal transfer. Journal of Ethnopharmacology 10.1016/j.jep.2019.111871. (In press).


Paredes, ME; Morales, RE; Lima, WK; Hu, S; Jurado, AL; Farchi, E; Prieto, JM; (2019) Morphoanatomical and phytochemical studies for the quality control of Neurolaena lobata (L.) R.Br. ex Cass. (Asteraceae). Blacpma (Boletín Latinoamericano Y Del Caribe De Plantas Medicinales Y Aromáticas) , 18 (3) pp. 277-288. Green open access

Penny, M; Rao, Z; Peniche, B; Hilton, S; (2019) Modular 3D Printed Compressed Air Driven Continuous‐Flow Systems for Chemical Synthesis. European Journal of Organic Chemistry 10.1002/ejoc.201900423. (In press).

Prieto, JM; Silveira, D; (2019) Natural Cytotoxic Diterpenoids, a Potential Source of Drug Leads for Melanoma Therapy. Current Pharmaceutical Design 10.2174/1381612825666190111143648. (In press). Green open access

Pérez-Cantero, A; Serrano, DR; Navarro-Rodríguez, P; Schätzlein, AG; Uchegbu, IF; Torrado, JJ; Capilla, J; (2019) Increased Efficacy of Oral Fixed-Dose Combination of Amphotericin B and AHCC® Natural Adjuvant against Aspergillosis. Pharmaceutics , 11 (9) , Article 456. 10.3390/pharmaceutics11090456. Green open access


Riccio, F; Talapatra, SK; Oxenford, S; Angell, R; Mazzon, M; Kozielski, F; (2019) Development and validation of RdRp Screen, a crystallization screen for viral RNA-dependent RNA polymerases. Biology Open , 8 , Article bio037663. 10.1242/bio.037663. Green open access

Romero, R; Ramanathan, A; Yuen, T; Bhowmik, D; Mathew, M; Munshi, LB; Javaid, S; ... Zaidi, M; + view all (2019) Mechanism of glucocerebrosidase activation and dysfunction in Gaucher disease unraveled by molecular dynamics and deep learning. Proceedings of the National Academy of Sciences of the United States of America 10.1073/pnas.1818411116. (In press). Green open access


Scotti, F; Lobel, K; Booker, A; Heinrich, M; (2019) St. John's Wort (Hypericum perforatum) Products - How Variable Is the Primary Material? Frontiers in Plant Science , 9 , Article 1973. 10.3389/fpls.2018.01973. Green open access

Soumyanarayanan, U; Ramanujulu, PM; Mustafa, N; Haider, S; Fang Nee, AH; Tong, JX; Tan, KSW; ... Dymock, BW; + view all (2019) Discovery of a potent histone deacetylase (HDAC) 3/6 selective dual inhibitor. European Journal of Medicinal Chemistry , 184 , Article 111755. 10.1016/j.ejmech.2019.111755.

Stowe, CL; Burley, TA; Allan, H; Vinci, M; Kramer-Marek, G; Ciobota, DM; Parkinson, GN; ... Pule, MA; + view all (2019) Near-infrared dual bioluminescence imaging in mouse models of cancer using infraluciferin. eLife , 8 , Article e45801. 10.7554/eLife.45801. (In press). Green open access


Timberlake, AT; Jin, SC; Nelson-Williams, C; Wu, R; Furey, CG; Islam, B; Haider, S; ... Lifton, RP; + view all (2019) Mutations in TFAP2B and previously unimplicated genes of the BMP, Wnt, and Hedgehog pathways in syndromic craniosynostosis. Proceedings of the National Academy of Sciences (PNAS) 10.1073/pnas.1902041116. (In press). Green open access

Todd, MH; (2019) Six Laws of Open Source Drug Discovery. [Editorial comment]. ChemMedChem 10.1002/cmdc.201900565. (In press). Green open access

Tse, EG; Korsik, M; Todd, MH; (2019) The past, present and future of anti-malarial medicines. Malaria Journal , 18 (1) , Article 93. 10.1186/s12936-019-2724-z. Green open access


Uchegbu, I; Wang, Z; Xiong, G; Tsang, A; Schatzlein, A; (2019) Nose to brain delivery. Journal of Pharmacology and Experimental Therapeutics , 370 (1) 10.1124/jpet.119.258152. (In press).


Van Melis, CGW; Penny, MR; Garcia, AD; Petti, A; Dobbs, AP; Hilton, ST; Lam, K; (2019) Supporting-Electrolyte-Free Electrochemical Methoxymethylation of Alcohols Using a 3D-Printed Electrosynthesis Continuous Flow Cell System. ChemElectroChem , 6 (16) pp. 4144-4148. 10.1002/celc.201900815.


Welker Leng, KR; Castañeda, CA; Decroos, C; Islam, B; Haider, SM; Christianson, DW; Fierke, CA; (2019) Phosphorylation of Histone Deacetylase 8: Structural and Mechanistic Analysis of the Phosphomimetic S39E Mutant. Biochemistry , 58 (45) pp. 4480-4493. 10.1021/acs.biochem.9b00653.


Yeung, AWK; Tzvetkov, NT; Gupta, VK; Gupta, SC; Orive, G; Bonn, GK; Fiebich, B; ... Atanasov, AG; + view all (2019) Current research in biotechnology: Exploring the biotech forefront. Current Research in Biotechnology 10.1016/j.crbiot.2019.08.003.


Zhai, Q; Gao, C; Ding, J; Zhang, Y; Islam, B; Lan, W; Hou, H; ... Wei, D; + view all (2019) Selective recognition of c-MYC Pu22 G-quadruplex by a fluorescent probe. Nucleic Acids Research , Article gkz059. 10.1093/nar/gkz059. (In press). Green open access

Zhang, Y; Lane, M; Hadgraft, J; Heinrich, M; Chen, T; Lian, G; Sinko, B; (2019) A comparison of the in vitro permeation of niacinamide in mammalian skin and in the Parallel Artificial Membrane Permeation Assay (PAMPA) model. International Journal of Pharmaceutics , 556 pp. 142-149. 10.1016/j.ijpharm.2018.11.065. Green open access

Zhang, Y; Sil, BC; Kung, C-P; Hadgraft, J; Heinrich, M; Sinko, B; Lane, ME; (2019) Characterization and topical delivery of phenylethyl resorcinol. International Journal of Cosmetic Science , 41 (5) pp. 479-488. 10.1111/ics.12565.

This list was generated on Mon Jan 27 20:04:49 2020 GMT.