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Number of items: 82.

A

Alkhatib, MN; Bedi, R; Foster, C; Jopanputra, P; Allan, S; (2005) Ethnic variations in orthodontic treatment need in London schoolchildren. BMC Oral Health , 5 , Article 8. 10.1186/1472-6831-5-8. Green open access
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Alkhatib, MN; Holt, RD; Bedi, R; (2005) Smoking and tooth discolouration: findings from a national cross-sectional study. BMC Public Health , 5 (Article ) pp. 1-4. Green open access
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Ambler, G; Omar, RZ; Royston, P; Kinsman, R; Keogh, BE; Taylor, KM; (2005) Generic, simple risk stratification model for heart valve surgery. Circulation , 112 (2) 224 - 231. 10.1161/CIRCULATIONAHA.104.515049. Green open access
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B

Beckett, K; (2005) The progression from contraction to contracture in Dupuytren’s derived fibroblasts: A study of the cellular and molecular events. Masters thesis , UNSPECIFIED.

Bellingan, G; (2005) Hooray for Hypoxia? PLoS Medicine , 2 (6) e130 -. 10.1371/journal.pmed.0020130. Green open access
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Bennett, CL; van Rijn, E; Jung, S; Inaba, K; Steinman, RM; Kapsenberg, ML; Clausen, BE; (2005) Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity. JOURNAL OF CELL BIOLOGY , 169 (4) pp. 569-576. 10.1083/jcb.200501071. Green open access
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Bhat, DS; Yajnik, CS; Sayyad, MG; Raut, KN; Lubree, HG; Rege, SS; Chougule, SD; ... Kurpad, AV; + view all (2005) Body fat measurement in Indian men: Comparison of three methods based on a two-compartment model. International Journal of Obesity , 29 (7) pp. 842-848. 10.1038/sj.ijo.0802953. Green open access
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Brady, M; Brown, R; Lewis, M; Mudera, V; (2005) Mechanical behaviour of primary human skeletal muscle cells and isolated non-myogenic cells within a 3D- construct. In: Abstracts of TCES (Tissue and Cell Engineering Society) meeting 2005 May 20-22, 2005 - Queen Mary, University of London. (pp. 29 - 29). Green open access
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Bukulmez, H; Fife, M; Tsoras, M; Thompson, SD; Twine, NA; Woo, P; Olson, JM; ... Colbert, RA; + view all (2005) Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study. ARTHRITIS RES THER , 7 (2) R285 - R290. 10.1186/ar1480. Green open access
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C

Choudhury, AI; Heffron, H; Smith, MA; Al-Qassab, H; Xu, AW; Selman, C; Simmgen, M; ... Withers, DJ; + view all (2005) The role of insulin receptor substrate 2 in hypothalamic and beta cell function. J CLIN INVEST , 115 (4) 940 - 950. Green open access
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Clapp, BR; Hirschfield, GM; Storry, C; Gallimore, JR; Stidwill, RP; Singer, M; Deanfield, JE; ... Hineorani, AD; + view all (2005) Inflammation and endothelial function: Direct vascular effects of human C-reactive protein on nitric oxide bioavailability. Circulation , 111 (12) pp. 1530-1536. 10.1161/01.CIR.0000159336.31613.31. Green open access
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Conti, L; Pollard, SM; Gorba, T; Reitano, E; Toselli, M; Biella, G; Sun, Y; ... Smith, A; + view all (2005) Niche-independent symmetrical self-renewal of a mammalian tissue stem cell. PLoS Biology , 3 (9) , Article e283. 10.1371/journal.pbio.0030283. Green open access
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Curry, JM; Whalan, R; Hunt, DM; Gohil, K; Strom, M; Rickman, L; Colston, MJ; ... Buxton, RS; + view all (2005) An ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in mice. INFECT IMMUN , 73 (8) 4471 - 4477. 10.1128/IAI.73.8.4471-4477.2005. Green open access
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D

Delves, PJ; Roitt, IM; (2005) Vaccines for the control of reproduction - Status in mammals, and aspects of comparative interest. PROGRESS IN FISH VACCINOLOGY , 121 pp. 265-273. Green open access
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Dogan, A; Du, MQ; Isaacson, PG; (2005) A relapsing inflammatory syndrome and HHV-8. NEW ENGLAND JOURNAL OF MEDICINE , 353 (16) p. 1746. Green open access
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Donoghue, HD; Marcsik, A; Matheson, C; Vernon, K; Nuorala, E; Molto, JE; Greenblatt, CL; (2005) Co-infection of Mycobacterium tuberculosis and Mycobacterium leprae in human archaeological samples: a possible explanation for the historical decline of leprosy. Proceedings of the Royal Society B , 272 (1561) 389 - 394. 10.1098/rspb.2004.2966. Green open access
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Dotti, G; Savoldo, B; Pule, M; Straathof, KC; Biagi, E; Yvon, E; Vigouroux, S; ... Rooney, CM; + view all (2005) lHuman cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis. BLOOD , 105 (12) 4677 - 4684. 10.1182/blood-2004-08-3337. Green open access
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Drew, LJ; Wood, JN; (2005) Worm sensation! Molecular Pain , 1 , Article 8. 10.1186/1744-8069-1-8. Green open access
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de Bruin, EC; van de Pas, S; Lips, EH; van Eijk, R; van der Zee, MM; Lombaerts, M; van Wezel, T; ... Peltenburg, LT; + view all (2005) Macrodissection versus microdissection of rectal carcinoma: minor influence of stroma cells to tumor cell gene expression profiles. BMC Genomics , 6 , Article 142. 10.1186/1471-2164-6-142. Green open access
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E

Ebrahimkhani, MR; Mani, AR; Moore, K; (2005) Hydrogen sulphide and the hyperdynamic circulation in cirrhosis: a hypothesis. GUT , 54 (12) pp. 1668-1671. 10.1136/gut.2004.056556. Green open access
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F

Feldmeyer, D; Roth, A; Sakmann, B; (2005) Monosynaptic connections between pairs of spiny stellate cells in layer 4 and pyramidal cells in layer 5A indicate that lemniscal and paralemniscal afferent pathways converge in the infragranular somatosensory cortex. Journal of Neuroscience , 25 (13) 3423 - 3431. 10.1523/JNEUROSCI.5227-04.2005. Green open access
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G

Gale, RE; Hills, R; Kottaridis, PD; Srirangan, S; Wheatley, K; Burnett, AK; Linch, DC; (2005) No evidence that FLT3 status should be considered as an indicator for transplantation in acute myeloid leukemia (AML): an analysis of 1135 patients, excluding acute promyelocytic leukemia, from the UK MRC AML 10 and 12 trials. BLOOD , 106 (10) 3658 - 3665. 10.1182/blood-2005-03-1323. Green open access
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Gale, RE; Hills, R; Pizzey, AR; Kottaridis, PD; Swirsky, D; Gilkes, AF; Nugent, E; ... NCRI Adult Leukaemia Working Party, ; + view all (2005) Relationship between FLT3 mutation status, biologic characteristics, and response to targeted therapy in acute promyelocytic leukemia. BLOOD , 106 (12) 3768 - 3776. Green open access
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Garson, J; Creange, A; Dolei, A; Ferrante, P; Jouvin-Marche, E; Marche, PN; Rieger, F; ... Perron, H; + view all (2005) MSRV, Syncytin and the role of endogenous retroviral proteins in demyelination. MULTIPLE SCLEROSIS JOURNAL , 11 (2) pp. 249-250. 10.1191/1352458505ms1160xx. Green open access
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Garson, JA; Grant, PR; Ayliffe, U; Ferns, RB; Tedder, RS; (2005) Real-time PCR quantitation of hepatitis B virus DNA using automated sample preparation and murine cytomegalovirus internal control. J VIROL METHODS , 126 (1-2) 207 - 213. 10.1016/j.jviromet.2005.03.001. Green open access
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Giles, I; Lambrianides, N; Latchman, D; Chen, P; Chukwuocha, R; Isenberg, D; Rahman, A; (2005) The critical role of arginine residues in the binding of human monoclonal antibodies to cardiolipin. Arthritis Research & Therapy , 7 (1) R47-R56. 10.1186/ar1449. Green open access
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Gillespie, SH; Basu, S; Dickens, AL; O'Sullivan, DM; McHugh, TD; (2005) Effect of subinhibitory concentrations of ciprofloxacin on Mycobacterium fortuitum mutation rates. J ANTIMICROB CHEMOTH , 56 (2) 344 - 348. 10.1093/jac/dki191. Green open access
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Gomez-Escobar, N; Bennett, C; Prieto-Lafuente, L; Aebischer, T; Blackburn, CC; Maizels, RM; (2005) Heterologous expression of the filarial nematode alt gene products reveals their potential to inhibit immune function. BMC Biology , 3 , Article 108. 10.1186/1741-7007-3-8. Green open access
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Gourley, C; Paige, AJW; Taylor, KJ; Scott, D; Francis, NJ; Rush, R; Aldaz, CM; ... Gabra, H; + view all (2005) WWOX mRNA expression profile in epithelial ovarian cancer supports the role of WWOX variant 1 as a tumour suppressor, although the role of variant 4 remains unclear. International Journal of Oncology , 26 (6) pp. 1681-1689. 10.3892/ijo.26.6.1681. Green open access
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Groszmann, RJ; Garcia-Tsao, G; Bosch, J; Grace, ND; Burroughs, AK; Planas, R; Escorsell, A; ... Portal Hypertension Collaborative Group, ; + view all (2005) Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis. N Engl J Med , 353 (21) pp. 2254-2261. 10.1056/NEJMoa044456. Green open access
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H

Harding, DR; Dhamrait, S; Devadason, D; Humphries, SE; Whitelaw, A; Marlow, N; Montgomery, HE; (2005) Does angiotensin-1 converting enzyme genotype influence motor or cognitive development after pre-term birth? JOURNAL OF NEUROINFLAMMATION , 2 (ARTN 6) 10.1186/1742-2094-2-6. Green open access
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Harris, JD; Graham, IR; Schepelmann, S; Stannard, AK; Amalfitano, A; Owen, JS; Dickson, G; (2005) Retardation of atherosclerosis in immunocompetent apolipoprotein (apo) E-deficient mice followingliver-directed administration of a [E1-, E3-,polymerase-] adenovirus vector containing the elongation factor-1a promoter driving expression of human apoE cDNA. Gene Therapy and Molecular Biology , 9 pp. 23-32. Green open access
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Henderson, SR; Guiliano, D; Presneau, N; McLean, S; Frow, R; Vujovic, S; Anderson, J; ... Boshoff, C; + view all (2005) A molecular map of mesenchymal tumors. GENOME BIOL , 6 (9) , Article R76. 10.1186/gb-2005-6-9-r76. Green open access
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I

Ioannou, Y; Bowman, SJ; Rahman, A; Giles, IP; (2005) Review of presentations at the 6th European Lupus Meeting 3-5 March 2005. Lupus , 14 (6) pp. 467-478. 10.1191/0961203305lu2172xx. Green open access
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J

Jenkins, C; Claxton, AP; Shorten, RJ; McHugh, TD; Gillespie, SH; (2005) Rifampicin resistance in tuberculosis outbreak, London, England. EMERG INFECT DIS , 11 (6) 931 - 934. Green open access
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Jones, M; Davidson, A; Hibbert, L; Gruenwald, P; Schlaak, J; Ball, S; Foster, G; (2005) Dengue virus inhibits alpha interferon signaling by reducing STAT2 expression. Journal of Virology , 79 (9) pp. 5414-5420. 10.1128/JVI.79.9.5414-5420.2005. Green open access
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K

Kanhere, A; Bansal, M; (2005) A novel method for prokaryotic promoter prediction based on DNA stability. BMC BIOINFORMATICS , 6 , Article 1. 10.1186/1471-2105-6-1. Green open access
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Kantor, R; Katzenstein, DA; Efron, B; Carvalho, AP; Wynhoven, B; Cane, P; Clarke, J; ... Shafer, RW; + view all (2005) Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLOS MED , 2 (4) , Article e112. 10.1371/journal.pmed.0020112. Green open access
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Karamichos, D; Brown, R; Mudera, V; (2005) Cellular responses to external mechanical stimuli when seeded to 3D collagen. In: European Cells and Materials. (pp. 60 - 60). Green open access
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Kenny, PA; Enver, T; Ashworth, A; (2005) Receptor and secreted targets of Wnt-I/beta-catenin signalling in mouse mammary epithelial cells. BMC Cancer , 5 , Article 3. 10.1186/1471-2407-5-3. Green open access
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Kirklin, D; (2005) The Search for Meaning in Modern Medicine. Doctoral thesis , UNSPECIFIED.

M

Malone, FD; Canick, JA; Ball, RH; Nyberg, DA; Comstock, CH; Bukowski, R; Berkowitz, RL; ... FASTER Res Consortium, ; + view all (2005) First-trimester or second-trimester screening, or both, for Down's syndrome. NEW ENGL J MED , 353 (19) 2001 - 2011. Green open access
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Mardas, NC; (2005) Bone formation with guided tissue regeneration and demineralized bone matrix. UNSPECIFIED thesis , UNSPECIFIED.

Mason, LJ; Lambrianides, A; Haley, JD; Manson, JJ; Latchman, DS; Isenberg, DA; Rahman, A; (2005) Stable expression of a recombinant human antinucleosome antibody to investigate relationships between antibody sequence, binding properties, and pathogenicity. Arthritis Research & Therapy , 7 (5) R971 - R983. 10.1186/ar1768. Green open access
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McCarthy, K.; (2005) The influence and expression of IGFBP-3 in normal and malignant breast tissue. Doctoral thesis , University of London. Green open access
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McManus, IC; (2005) Unity in the wild variety of nature, or just variety? BEHAV BRAIN SCI , 28 (4) 606 -608. 10.1017/S0140525X05400102. Green open access
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McManus, IC; Iqbal, S; Chandrarajan, A; Ferguson, E; Leaviss, J; (2005) Unhappiness and dissatisfaction in doctors cannot be predicted by selectors from medical school application forms: a prospective, longitudinal study. BMC Medical Education , 5 , Article 38. 10.1186/1472-6920-5-38. Green open access
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McManus, IC; Mollon, J; Duke, OL; Vale, JA; (2005) Changes in standard of candidates taking the MRCP(UK) Part 1 examination, 1985 to 2002: Analysis of marker questions. BMC Medicine , 3 , Article 13. 10.1186/1741-7015-3-13. Green open access
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Meaburn, E; Butcher, LM; Liu, L; Fernandes, C; Hansen, V; Al-Chalabi, A; Plomin, R; ... Schalkwyk, LC; + view all (2005) Genotyping DNA pools on microarrays: tackling the QTL problem of large samples and large numbers of SNPs. BMC Genomics , 6 , Article 52. 10.1186/1471-2164-6-52. Green open access
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Montagnese, S; Gordon, HM; Jackson, C; Smith, J; Tognella, P; Jethwa, N; Sherratt, RM; (2005) Disruption of smooth pursuit eye movements in cirrhosis: relationship to hepatic encephalopathy and its treatment. Hepatology , 42 (4) pp. 772-781. 10.1002/hep.20855. Green open access
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Morrissey, A; Rosner, E; Lanning, J; Parachuru, L; Dhar Chowdhury, P; Han, S; Lopez, G; ... Coetzee, WA; + view all (2005) Immunolocalization of KATP channel subunits in mouse and rat cardiac myocytes and the coronary vasculature. BMC Physiol , 5 (1) 1-. 10.1186/1472-6793-5-1. Green open access
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Murray, CDR; Martin, NM; Patterson, M; Taylor, SA; Ghatei, MA; Kamm, MA; Johnston, C; ... Emmanuel, AV; + view all (2005) Ghrelin enhances gastric emptying in diabetic gastroparesis: a double blind, placebo controlled, crossover study. GUT , 54 (12) pp. 1693-1698. 10.1136/gut.2005.069088. Green open access
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N

Nassar, MA; Levato, A; Stirling, LC; Wood, JN; (2005) Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8. Molecular Pain , 1 , Article 24. 10.1186/1744-8069-1-24. Green open access
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Norman, MW; Simpson, M; Mogensen, J; Shaw, A; Hughes, S; Sen-Chowdhry, S; Rowland, E; ... McKenna, WJ; + view all (2005) A novel mutation in desmoplakin causes arrhythmogenic left ventricular cardiomyopathy. Circulation , 112 (5) pp. 636-642. Green open access
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O

O'Mahony, R; Basset, C; Holton, J; Vaira, D; Roitt, I; (2005) Comparison of image analysis software packages in the assessment of adhesion of microorganisms to mucosal epithelium using confocal laser scanning microscopy. Journal of Microbiological Methods , 61 (1) pp. 105-126. Green open access
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O'Sullivan, DM; McHugh, TD; Gillespie, SH; (2005) Analysis of rpoB and pncA mutations in the published literature: an insight into the role of oxidative stress in Mycobacterium tuberculosis evolution? J ANTIMICROB CHEMOTH , 55 (5) 674 - 679. 10.1093/jac/dki069. Green open access
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P

Pan-Hammarstrom, Q; Jones, AM; Lahdesmaki, A; Zhou, W; Gatti, RA; Hammarstrom, L; Gennery, AR; (2005) Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells. J EXP MED , 201 (2) 189 - 194. 10.1084/jem.20040772. Green open access
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Paterson, PJ; Seaton, S; Yeghen, T; McHugh, TD; McLaughlin, J; Hoffbrand, AV; Kibbler, CC; (2005) Molecular confirmation of invasive infection caused by Chaetomium globosum [1]. Journal of Clinical Pathology , 58 (3) 334-. Green open access
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Pereira, SP; Rowbotham, D; Fitt, S; Shearer, MJ; Wendon, J; Williams, R; (2005) Pharmacokinetics and efficacy of oral versus intravenous mixed-micellar phylloquinone (vitamin K-1) in severe acute liver disease. J HEPATOL , 42 (3) 365 - 370. 10.1016/j.jhep.2004.11.030. Green open access
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Perrin, FMR; Breen, RAM; Lipman, MCI; Shorten, RJ; Gillespie, SH; McHugh, TD; (2005) Is there a relationship between Mycobacterium tuberculosis strain type and TB paradoxical reaction? THORAX , 60 (8) 706 - 707. 10.1136/thx.2005.044321. Green open access
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Peters, C.; (2005) A prospective comparative study of 5 year old children (and their families) born after intracytoplasmic sperm injection, conventional in vitro fertilisation or natural conception; and other studies of child/family outcome after in-vitro fertilisation techniques. Doctoral thesis , University of London. Green open access
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R

Raza, K; Falciani, F; Curnow, SJ; Ross, EJ; Lee, CY; Akbar, AN; Lord, JM; ... Salmon, M; + view all (2005) Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin. ARTHRITIS RES THER , 7 (4) R784 - R795. 10.1186/ar1733. Green open access
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Reinhardt, AK; Bottoms, SE; Laurent, GJ; McAnulty, RJ; (2005) Quantification of collagen and proteoglycan deposition in a murine model of airway remodelling. RESP RES , 6 , Article 30. 10.1186/1465-9921-6-30. Green open access
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Rook, GAW; Brunet, LR; (2005) Microbes, immunoregulation, and the gut. GUT , 54 (3) 317 - 320. 10.1136/gut.2004.053785. Green open access
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Rook, GAW; Brunet, LR; (2005) Old friends for breakfast. CLIN EXP ALLERGY , 35 (7) 841 - 842. 10.1111/j.1365-2222.2005.02112.x. Green open access
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Rook, GAW; Dheda, K; Zumla, A; (2005) Do successful tuberculosis vaccines need to be immunoregulatory rather than merely Th1-boosting? VACCINE , 23 (17-18) 2115 - 2120. Green open access
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Rook, GAW; Martinelli, R; Brunet, LR; (2005) Modelling gene-environment interactions in Th1- and Th2-dominated diseases of laboratory animals. ANIMAL MODELS OF T CELL-MEDIATED SKIN DISEASES , 50 pp. 45-68. Green open access
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S

Sambrook, JG; Figueroa, F; Beck, S; (2005) A genome-wide survey of Major Histocompatibility Complex (MHC) genes and their paralogues in zebrafish. BMC GENOMICS , 6 , Article 152. 10.1186/1471-2164-6-152. Green open access
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Shawcross, D; Jalan, R; (2005) Dispelling myths in the treatment of hepatic encephalopathy. LANCET , 365 (9457) 431 - 433. Green open access
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Sieben, NLG; Oosting, J; Flanagan, AM; Prat, J; Roemen, GMJM; Kolkman-Uljee, SM; van Eijk, R; ... van Engeland, M; + view all (2005) Differential gene expression in ovarian tumors reveals Dusp 4 and Serpina 5 as key regulators for benign behavior of serous borderline tumors. Journal of Clinical Oncology , 23 (29) 7257 - 7264. 10.1200/JCO.2005.02.2541.

Singer, M; Glynne, P; (2005) Treating critical illness: The importance of first doing no harm. PLoS Medicine , 2 (6) , Article e167. 10.1371/journal.pmed.0020167. Green open access
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Smith, CL; Anthony, S; Hubank, M; Leiper, JM; Vallance, P; (2005) Effects of ADMA upon gene expression: an insight into the pathophysiological significance of raised plasma ADMA. PLoS Medicine , 2 (10) , Article e264. 10.1371/journal.pmed.0020264. Green open access
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Soueid, A; Hall, S; Mudera, V; (2005) Profile of pulmonary smooth muscle cells and their response to blockade and Stimulations. In: European Cells and Materials. (pp. 19 - 19). Green open access
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Spigelman, M; Greenblatt, CL; Vernon, K; Zylber, MI; Sheridan, SG; Van Gerven, DP; Shaheem, Z; ... Donoghue, HD; + view all (2005) Preliminary findings on the paleomicrobiological study of 400 naturally mummified human remains from upper Nubia. Journal of Biological Research , 80 (1) 91 - 95. Green open access
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Straathof, KC; Pule, MA; Yotnda, P; Dotti, G; Vanin, EF; Brenner, MK; Heslop, HE; ... Rooney, CM; + view all (2005) An inducible caspase 9 safety switch for T-cell therapy. BLOOD , 105 (11) pp. 4247-4254. 10.1182/blood-2004-11-4564. Green open access
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Swinglehurst, DA; (2005) Information needs of United Kingdom primary care clinicians. HEALTH INFO LIBR J , 22 (3) 196 - 204. Green open access
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T

Tagalakis, AD; Diakonov, IA; Graham, IR; Heald, KA; Harris, JD; Mulcahy, JV; Dickson, G; (2005) Apolipoprotein E delivery by peritoneal implantation of encapsulated recombinant cells improves the hyperlipidaemic profile in apoE-deficient mice. BBA-MOL CELL BIOL L , 1686 (3) 190 - 199. 10.1016/j.bbalip.2004.10.001. Green open access
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Tagalakis, AD; Dickson, JG; Owen, JS; Simons, JP; (2005) Correction of the neuropathogenic human apolipoprotein E4 (APOE4) gene to APOE3 in vitro using synthetic RNA/DNA oligonucleotides (chimeraplasts). J MOL NEUROSCI , 25 (1) 95 - 103. Green open access
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Tagalakis, AD; Owen, JS; Simons, JP; (2005) Lack of RNA-DNA oligonucleotide (chimeraplast) mutagenic activity in mouse embryos. MOL REPROD DEV , 71 (2) 140 - 144. 10.1002/mrd.20250. Green open access
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Thilakawardhana, S; Everett, DM; Murdock, PR; Dingwall, C; Owen, JS; (2005) Quantification of apolipoprotein E receptors in human brain-derived cell lines by real-time polymerase chain reaction. NEUROBIOLOGY OF AGING , 26 (6) 813 - 823. 10.1016/j.neurobiolaging.2004.08.004. Green open access
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V

von Hertzen, LSJ; Giese, KP; (2005) Memory reconsolidation engages only a subset of immediate-early genes induced during consolidation. Journal of Neuroscience , 25 (8) 1935 - 1942. Green open access
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W

West, H; Richardson, WD; Fruttiger, M; (2005) Stabilization of the retinal vascular network by reciprocal feedback between blood vessels and astrocytes. DEVELOPMENT , 132 (8) 1855 - 1862. 10.1242/dev.01732. Green open access
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This list was generated on Sun Dec 8 21:39:28 2019 GMT.