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Number of items: 80.
A
Abu-Hanna, J;
Tannman, J-W;
Abraham, D;
Clapp, L;
(2019)
Treprostinil signals via the IP or EP2 receptor to inhibit dynamin-related protein (DRP1) and promote mitochondrial elongation in pulmonary arterial smooth muscle cells (PASMCs) from patients with pulmonary arterial hypertension (PAH).
Presented at: Pharmacology 2018, London, UK.
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Alexander, SPH;
Christopoulos, A;
Davenport, AP;
Kelly, E;
Mathie, A;
Peters, JA;
Veale, EL;
... CGTP Collaborators; + view all
(2019)
THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein-coupled receptors.
British Journal of Pharmacology
, 176
(S1)
S21-S141.
10.1111/bph.14748.
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Andreadou, I;
Cabrera-Fuentes, HA;
Devaux, Y;
Frangogiannis, NG;
Frantz, S;
Guzik, T;
Liehn, E;
... Hausenloy, DJ; + view all
(2019)
Immune cells as targets for cardioprotection: New players and novel therapeutic opportunities.
Cardiovascular Research
, 115
(7)
pp. 1117-1130.
10.1093/cvr/cvz050.
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Arjun, S;
Bell, RM;
(2019)
SGLT2 inhibitors: reviving the sodium-hydrogen exchanger cardioprotection hypothesis?
[Editorial comment].
Cardiovascular Research
, 115
(10)
pp. 1454-1456.
10.1093/cvr/cvz105.
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Attrill, H;
Gaudet, P;
Huntley, RP;
Lovering, RC;
Engel, SR;
Poux, S;
Van Auken, KM;
... Gene Ontology Consortium; + view all
(2019)
Annotation of gene product function from high-throughput studies using the Gene Ontology.
Database
, 2019
, Article baz007. 10.1093/database/baz007.
(In press).
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B
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Bandres-Ciga, S;
Ahmed, S;
Sabir, MS;
Blauwendraat, C;
Adarmes-Gomez, AD;
Bernal-Bernal, I;
Bonilla-Toribio, M;
... Singleton, A; + view all
(2019)
The Genetic Architecture of Parkinson Disease in Spain: Characterizing Population-Specific Risk, Differential Haplotype Structures, and Providing Etiologic Insight.
Movement Disorders
10.1002/mds.27864.
(In press).
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Bandres-Ciga, S;
Saez-Atienzar, S;
Bonet-Ponce, L;
Billingsley, K;
Vitale, D;
Blauwendraat, C;
Gibbs, JR;
... Singleton, AB; + view all
(2019)
The endocytic membrane trafficking pathway plays a major role in the risk of Parkinson's disease.
Movement Disorders
, 34
(4)
pp. 460-468.
10.1002/mds.27614.
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Basalay, MV;
Davidson, SM;
Yellon, DM;
(2019)
Neuroprotection in Rats Following Ischaemia-Reperfusion Injury by GLP-1 Analogues—Liraglutide and Semaglutide.
Cardiovascular Drugs and Therapy
10.1007/s10557-019-06915-8.
(In press).
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Bell, RM;
(2019)
Antihyperglycemic drugs that improve cardiovascular outcomes and a model of diabetic cardiomyopathy.
Heart and Metabolism
(80)
pp. 18-22.
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Best, JG;
Bell, R;
Haque, M;
Chandratheva, A;
Werring, DJ;
(2019)
Atrial fibrillation and stroke: a practical guide.
Practical Neurology
, 19
(3)
pp. 208-224.
10.1136/practneurol-2018-002089.
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Bibli, S-I;
Papapetropoulos, A;
Iliodromitis, EK;
Daiber, A;
Randriamboavonjy, V;
Steven, S;
Brouckaert, P;
... Andreadou, I; + view all
(2019)
Nitroglycerine limits infarct size through S-nitrosation of cyclophilin D: a novel mechanism for an old drug.
Cardiovascular Research
, 115
(3)
pp. 625-636.
10.1093/cvr/cvy222.
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Billingsley, KJ;
Barbosa, IA;
Bandrés-Ciga, S;
Quinn, JP;
Bubb, VJ;
Deshpande, C;
Botia, JA;
... Koks, S; + view all
(2019)
Mitochondria function associated genes contribute to Parkinson's Disease risk and later age at onset.
npj Parkinson's Disease
, 5
, Article 8. 10.1038/s41531-019-0080-x.
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Breyer, RM;
Clapp, L;
Coleman, RA;
Giembycz, M;
Heinemann, A;
Hills, R;
Jones, RL;
... Yao, C; + view all
(2019)
Prostanoid receptors (version 2019.5) in the IUPHAR/BPS Guide to Pharmacology Database.
IUPHAR/BPS Guide to Pharmacology CITE
, 2019
(5)
10.2218/gtopdb/F58/2019.5.
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Breyer, RM;
Clapp, L;
Coleman, RA;
Giembycz, M;
Heinemann, A;
Hills, R;
Jones, RL;
... Yao, C; + view all
(2019)
Prostanoid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database.
IUPHAR/BPS Guide to Pharmacology CITE
, 2019
(4)
10.2218/gtopdb/f58/2019.4.
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Bromage, DI;
Godec, TR;
Pujades-Rodriguez, M;
Gonzalez-Izquierdo, A;
Denaxas, S;
Hemingway, H;
Yellon, DM;
(2019)
Metformin use and cardiovascular outcomes after acute myocardial infarction in patients with type 2 diabetes: a cohort study.
Cardiovascular Diabetology
, 18
, Article 168. 10.1186/s12933-019-0972-4.
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Bromage, DI;
Taferner, S;
He, Z;
Ziff, OJ;
Yellon, DM;
Davidson, SM;
(2019)
Stromal cell-derived factor-1α signals via the endothelium to protect the heart against ischaemia-reperfusion injury.
Journal of Molecular and Cellular Cardiology
, 128
pp. 187-197.
10.1016/j.yjmcc.2019.02.002.
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Brown, P;
Tan, A-C;
El-Esawi, MA;
Liehr, T;
Blanck, O;
Gladue, DP;
Almeida, GMF;
... Shalchyan, V; + view all
(2019)
Large expert-curated database for benchmarking document similarity detection in biomedical literature search.
Database
pp. 1-66.
10.1093/database/baz085.
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Bulluck, H;
Chan, M;
Bryant, J;
Chai, P;
Chawla, A;
Chua, T;
Chung, Y-C;
... Hausenloy, DJ; + view all
(2019)
Platelet inhibition to target reperfusion injury trial: Rationale and study design.
Clinical Cardiology
, 42
(1)
pp. 5-12.
10.1002/clc.23110.
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Bulluck, H;
Fröhlich, GM;
Nicholas, JM;
Mohdnazri, S;
Gamma, R;
Davies, J;
Sirker, A;
... Hausenloy, DJ; + view all
(2019)
Mineralocorticoid receptor antagonist pre-treatment and early post-treatment to minimize reperfusion injury after ST-elevation myocardial infarction: The MINIMIZE STEMI trial.
American Heart Journal
, 211
pp. 60-67.
10.1016/j.ahj.2019.02.005.
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Bulluck, H;
Zheng, H;
Chan, MY;
Foin, N;
Foo, DC;
Lee, CW;
Lim, ST;
... Hausenloy, DJ; + view all
(2019)
Independent Predictors of Cardiac Mortality and Hospitalization for Heart Failure in a Multi-Ethnic Asian ST-segment Elevation Myocardial Infarction Population Treated by Primary Percutaneous Coronary Intervention.
Scientific Reports
, 9
, Article 100. 10.1038/s41598-019-46486-0.
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C
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Cho, YJ;
Nam, K;
Kim, TK;
Choi, SW;
Kim, SJ;
Hausenloy, DJ;
Jeon, Y;
(2019)
Sevoflurane, Propofol and Carvedilol Block Myocardial Protection by Limb Remote Ischemic Preconditioning.
International Journal of Molecular Sciences
, 20
(2)
, Article 269. 10.3390/ijms20020269.
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Chong, J;
Bulluck, H;
Fw Ho, A;
Boisvert, WA;
Hausenloy, DJ;
(2019)
Chronic remote ischemic conditioning for cardiovascular protection.
Conditioning Medicine
, 2
(4)
pp. 164-169.
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Chong, J;
Ho, AF;
Yap, J;
Bulluck, H;
Hausenloy, DJ;
(2019)
Is there a role for remote ischemic conditioning in preventing 5-fluorouracil-induced coronary vasospasm?
Conditioning Medicine
, 2
(5)
pp. 204-212.
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Coghlan, JG;
Picken, C;
Clapp, LH;
(2019)
Selexipag in the management of pulmonary arterial hypertension: an update.
Drug, Healthcare and Patient Safety
, 11
pp. 55-64.
10.2147/DHPS.S181313.
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D
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Davidson, SM;
(2019)
FAM3A – A mitochondrial route to the stimulation of angiogenesis?
EBioMedicine
, 43
pp. 3-4.
10.1016/j.ebiom.2019.04.033.
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Davidson, SM;
Andreadou, I;
Barile, L;
Birnbaum, Y;
Cabrera-Fuentes, HA;
Cohen, MV;
Downey, JM;
... Ferdinandy, P; + view all
(2019)
Circulating blood cells and extracellular vesicles in acute cardioprotection.
Cardiovascular Research
, 115
(7)
pp. 1156-1166.
10.1093/cvr/cvy314.
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Davidson, SM;
Andreadou, I;
Garcia-Dorado, D;
Hausenloy, DJ;
(2019)
Shining the spotlight on cardioprotection: beyond the cardiomyocyte.
Cardiovascular Research
, 115
(7)
pp. 1115-1116.
10.1093/cvr/cvz072.
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Davidson, SM;
Ferdinandy, P;
Andreadou, I;
Bøtker, HE;
Heusch, G;
Ibáñez, B;
Ovize, M;
... CARDIOPROTECTION COST Action (CA16225); + view all
(2019)
Multitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury: JACC Review Topic of the Week.
Journal of the American College of Cardiology
, 73
(1)
pp. 89-99.
10.1016/j.jacc.2018.09.086.
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Davidson, SM;
Szabadkai, G;
Duchen, MR;
(2019)
Fantastic beasts and how to find them—Molecular identification of the mitochondrial ATP-sensitive potassium channel.
Cell Calcium
, 84
, Article 102100. 10.1016/j.ceca.2019.102100.
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Davis, SPX;
Kumar, S;
Alexandrov, Y;
Bhargava, A;
da Silva Xavier, G;
Rutter, GA;
Frankel, P;
... McGinty, J; + view all
(2019)
Convolutional neural networks for reconstruction of undersampled optical projection tomography data applied to in vivo imaging of zebrafish.
Journal of Biophotonics
, Article e201900128. 10.1002/jbio.201900128.
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Del-Toro, N;
Duesbury, M;
Koch, M;
Perfetto, L;
Shrivastava, A;
Ochoa, D;
Wagih, O;
... IMEx Consortium contributing authors, .; + view all
(2019)
Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set.
Nature Communications
, 10
, Article 10. 10.1038/s41467-018-07709-6.
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del-Toro, N;
Khadake, J;
Meldal, B;
Panni, S;
Thorneycroft, D;
van Roey, K;
Abbani, S;
... Raghunath, A; + view all
(2019)
Publisher Correction: Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set.
[Corrigendum].
Nature Communications
, 10
, Article 1098. 10.1038/s41467-019-08814-w.
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F
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Fiedler, LR;
Chapman, K;
Xie, M;
Maifoshie, E;
Jenkins, M;
Golforoush, PA;
Bellahcene, M;
... Schneider, MD; + view all
(2019)
MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo.
Cell Stem Cell
10.1016/j.stem.2019.01.013.
(In press).
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H
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Hall, CL;
Gurha, P;
Sabater-Molina, M;
Asimaki, A;
Futema, M;
Lovering, RC;
Suárez, MP;
... Syrris, P; + view all
(2019)
RNA sequencing-based transcriptome profiling of cardiac tissue implicates novel putative disease mechanisms in FLNC-associated arrhythmogenic cardiomyopathy.
International Journal of Cardiology
10.1016/j.ijcard.2019.12.002.
(In press).
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Hamarneh, Ashraf Atef Jiries;
(2019)
The effect of remote ischaemic conditioning and glyceryl trinitrate on perioperative myocardial injury in cardiac bypass surgery patients.
Doctoral thesis (M.D(Res)), UCL (University College London).
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Hausenloy, D;
Davidson, SM;
(2019)
David Garcia-Dorado: a true pioneer in cardiac ischaemia/reperfusion injury.
Cardiovascular Research
, 115
(14)
e177-e180.
10.1093/cvr/cvz282.
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Hausenloy, DJ;
Bøtker, HE;
(2019)
Why did remote ischaemic conditioning not improve clinical outcomes in acute myocardial infarction in the CONDI-2/ERIC-PPCI trial?
Cardiovascular Research
, 115
(14)
e161-e163.
10.1093/cvr/cvz242.
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Hausenloy, DJ;
Bøtker, HE;
Ferdinandy, P;
Heusch, G;
Ng, GA;
Redington, A;
Garcia-Dorado, D;
(2019)
Cardiac innervation in acute myocardial ischaemia/reperfusion injury and cardioprotection.
Cardiovascular Research
, 115
(7)
pp. 1167-1177.
10.1093/cvr/cvz053.
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Hausenloy, DJ;
Heusch, G;
(2019)
Translating Cardioprotection for Patient Benefit The EU-CARDIOPROTECTION COST Action.
Journal of the American College of Cardiology
, 73
(15)
pp. 2001-2003.
10.1016/j.jpcc.2019.03.020.
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Hausenloy, DJ;
Kharbanda, RK;
Møller, UK;
Ramlall, M;
Aarøe, J;
Butler, R;
Bulluck, H;
... CONDI-2/ERIC-PPCI Investigators; + view all
(2019)
Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial.
Lancet
10.1016/S0140-6736(19)32039-2.
(In press).
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Hausenloy, DJ;
Lim, MX;
Chan, MHH;
Paradies, V;
Francis, R;
Kotecha, T;
Knight, DS;
... Bulluck, H; + view all
(2019)
Interrogation of the infarcted and salvaged myocardium using multi-parametric mapping cardiovascular magnetic resonance in reperfused ST-segment elevation myocardial infarction patients.
Scientific Reports
, 9
(1)
, Article 9056. 10.1038/s41598-019-45449-9.
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Ho, AFW;
Zheng, H;
Earnest, A;
Cheong, KH;
Pek, PP;
Seok, JY;
Liu, N;
... Ong, MEH; + view all
(2019)
Time-Stratified Case Crossover Study of the Association of Outdoor Ambient Air Pollution With the Risk of Acute Myocardial Infarction in the Context of Seasonal Exposure to the Southeast Asian Haze Problem.
Journal of the American Heart Association
, 8
(6)
, Article e011272. 10.1161/JAHA.118.011272.
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I
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Ibanez, B;
Aletras, AH;
Arai, AE;
Arheden, H;
Bax, J;
Berry, C;
Bucciarelli-Ducci, C;
... Fuster, V; + view all
(2019)
Cardiac MRI Endpoints in Myocardial Infarction Experimental and Clinical Trials: JACC Scientific Expert Panel.
Journal of the American College of Cardiology
, 74
(2)
pp. 238-256.
10.1016/j.jacc.2019.05.024.
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J
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Jensen, RV;
Andreadou, I;
Hausenloy, DJ;
Bøtker, HE;
(2019)
The Role of O-GlcNAcylation for Protection against Ischemia-Reperfusion Injury.
International Journal of Molecular Sciences
, 20
(2)
, Article 404. 10.3390/ijms20020404.
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K
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Kapoor, M;
Spillane, J;
Englezou, C;
Sarri-Gonzalez, S;
Bell, R;
Rossor, A;
Manji, H;
... Carr, A; + view all
(2019)
Thromboembolic risk with IVIg: Incidence and risk factors in inflammatory neuropathy patients.
Neurology
10.1212/WNL.0000000000008742.
(In press).
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Kleinbongard, P;
Bøtker, HE;
Ovize, M;
Hausenloy, DJ;
Heusch, G;
(2019)
Co-morbidities and co-medications as confounders of cardioprotection - does it matter in the clinical setting?
British Journal of Pharmacology
10.1111/bph.14839.
(In press).
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Köhler, S;
Carmody, L;
Vasilevsky, N;
Jacobsen, JOB;
Danis, D;
Gourdine, J-P;
Gargano, M;
... Robinson, PN; + view all
(2019)
Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources.
Nucleic Acids Research
, 47
(D1)
D1018-D1027.
10.1093/nar/gky1105.
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Koopmans, F;
Van Nierop, P;
Andres-Alonso, M;
Byrnes, A;
Cijsouw, T;
Coba, MP;
Cornelisse, LN;
... Verhage, M; + view all
(2019)
SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse.
Neuron
, 103
(2)
217-234.e4.
10.1016/j.neuron.2019.05.002.
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L
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Lin, Y-H;
Yap, J;
Ramachandra, CJA;
Hausenloy, DJ;
(2019)
New insights provided by myofibril mechanics in inherited cardiomyopathies.
Conditioning Medicine
, 2
(5)
pp. 213-224.
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Lowe, V;
Wisniewski, L;
Sayers, J;
Evans, I;
Frankel, P;
Mercader-Huber, N;
Zachary, IC;
(2019)
Neuropilin 1 mediates epicardial activation and revascularization in the regenerating zebrafish heart.
Development
10.1242/dev.174482.
(In press).
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M
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Madonna, R;
Van Laake, LW;
Botker, HE;
Davidson, SM;
De Caterina, R;
Engel, FB;
Eschenhagen, T;
... Sluijter, JPG; + view all
(2019)
ESC Working Group on Cellular Biology of the Heart: Tissue Engineering and Cell-Based Therapies for Cardiac Repair in Ischemic Heart Disease and Heart Failure.
Cardiovascular Research
, 115
(3)
pp. 488-500.
10.1093/cvr/cvz010.
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Mei, Q;
Bansal, A;
Jayakumar, MKG;
Zhang, Z;
Zhang, J;
Huang, H;
Yu, D;
... Zhang, Y; + view all
(2019)
Manipulating energy migration within single lanthanide activator for switchable upconversion emissions towards bidirectional photoactivation.
Nature Communications
, 10
(1)
p. 4416.
10.1038/s41467-019-12374-4.
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Mele, L;
Maskell, LJ;
Stuckey, DJ;
Clark, JE;
Heads, RJ;
Budhram-Mahadeo, VS;
(2019)
The POU4F2/Brn-3b transcription factor is required for the hypertrophic response to angiotensin II in the heart.
Cell Death & Disease
, 10
, Article 621. 10.1038/s41419-019-1848-y.
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N
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Nagel, E;
Greenwood, JP;
McCann, GP;
Bettencourt, N;
Shah, AM;
Hussain, ST;
Perera, D;
... MR-INFORM Investigators; + view all
(2019)
Magnetic Resonance Perfusion or Fractional Flow Reserve in Coronary Disease.
The New England Journal of Medicine
, 380
(25)
pp. 2418-2428.
10.1056/NEJMoa1716734.
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Nalls, MA;
Blauwendraat, C;
Vallerga, CL;
Heilbron, K;
Bandres-Ciga, S;
Chang, D;
Tan, M;
... Guerreiro, R; + view all
(2019)
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies.
The Lancet Neurology
, 18
(12)
pp. 1091-1102.
10.1016/S1474-4422(19)30320-5.
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Niccoli, G;
Montone, RA;
Ibanez, B;
Thiele, H;
Crea, F;
Heusch, G;
Bulluck, H;
... Eitel, I; + view all
(2019)
Optimized Treatment of ST-Elevation Myocardial Infarction The Unmet Need to Target Coronary Microvascular Obstruction as Primary Treatment Goal to Further Improve Prognosis.
Circulation Research
, 125
(2)
pp. 245-258.
10.1161/CIRCRESAHA.119.315344.
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O
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Ong, S-B;
Kwek, X-Y;
Katwadi, K;
Hernandez-Resendiz, S;
Crespo-Avilan, GE;
Ismail, NI;
Lin, Y-H;
... Hausenloy, DJ; + view all
(2019)
Targeting Mitochondrial Fission Using Mdivi-1 in A Clinically Relevant Large Animal Model of Acute Myocardial Infarction: A Pilot Study.
International Journal of Molecular Sciences
, 20
(16)
, Article 3972. 10.3390/ijms20163972.
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P
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Perfetto, L;
Acencio, ML;
Bradley, G;
Cesareni, G;
Del Toro, N;
Fazekas, D;
Hermjakob, H;
... Licata, L; + view all
(2019)
CausalTAB: the PSI-MITAB 2.8 updated format for signalling data representation and dissemination.
Bioinformatics
, 35
(19)
pp. 3779-3785.
10.1093/bioinformatics/btz132.
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Petri, A;
Kim, HJ;
Xu, Y;
De Groot, R;
Li, C;
Vandenbulcke, A;
Vanhoorelbeke, K;
... Crawley, JTB; + view all
(2019)
Crystal structure and substrate-induced activation of ADAMTS13.
Nature Communications
, 10
, Article 3781. 10.1038/s41467-019-11474-5.
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Picken, C;
Konstantinos, F;
Eddama, M;
Coghlan, G;
Clapp, L;
(2019)
Adverse events of prostacyclin mimetics in pulmonary arterial hypertension: a systematic review and meta-analysis.
Journal of Clinical Medicine
, 8
(4)
, Article 481. 10.3390/jcm8040481.
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Pong, JZ;
Ho, AFW;
Tan, TXZ;
Zheng, H;
Pek, PP;
Sia, C-H;
Hausenloy, DJ;
(2019)
ST-segment elevation myocardial infarction with non-chest pain presentation at the Emergency Department: Insights from the Singapore Myocardial Infarction Registry.
Internal and Emergency Medicine
, 14
pp. 989-997.
10.1007/s11739-019-02122-3.
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R
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Raees, A;
Backhamis, A;
Mohamed-Ali, V;
Bashah, M;
Al-Jaber, M;
Abraham, D;
Clapp, LH;
(2019)
Altered cyclooxygenase-1 and enhanced thromboxane receptor activities underlie attenuated endothelial dilatory capacity of omental arteries in obesity.
Life Sciences
, 239
, Article 117039. 10.1016/j.lfs.2019.117039.
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Rahmani, B;
McGregor, C;
Byrne, G;
Burriesci, G;
(2019)
A Durable Porcine Pericardial Surgical Bioprosthetic HeartValve: a Proof of Concept.
Journal of Cardiovascular Translational Research
10.1007/s12265-019-09868-3.
(In press).
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Ramachandra, CJA;
Mai Ja, KPM;
Lin, Y-H;
Shim, W;
Boisvert, WA;
Hausenloy, DJ;
(2019)
Induced pluripotent stem cells for modeling energetic alterations in hypertrophic cardiomyopathy.
Conditioning Medicine
, 2
(4)
pp. 142-151.
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Rauf, A;
Shah, M;
Yellon, DM;
Davidson, SM;
(2019)
Role of Caspase 1 in Ischemia/Reperfusion Injury of the Myocardium.
Journal of Cardiovascular Pharmacology
, 74
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