Browse by UCL Departments and Centres
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Number of items: 100.
A
Abdollah, MRA;
(2016)
Developing superparamagnetic iron oxide nanoparticles as targeted cancer nanomedicine.
Doctoral thesis , UCL (University College London).
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Alliouachene, S;
Bilanges, B;
Chaussade, C;
Pearce, W;
Foukas, LC;
Scudamore, CL;
Moniz, LS;
(2016)
Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice.
Diabetologia
, 59
(7)
pp. 1503-1512.
10.1007/s00125-016-3963-y.
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Ang, JE;
Pandher, R;
Ang, JC;
Asad, YJ;
Henley, A;
Valenti, M;
Box, G;
... Raynaud, FI; + view all
(2016)
Plasma metabolomic changes following PI3K inhibition as pharmacodynamic biomarkers: preclinical discovery to Phase I trial evaluation.
Molecular Cancer Therapeutics
, 15
(6)
pp. 1412-1424.
10.1158/1535-7163.MCT-15-0815.
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Anjos-Afonso, F;
Loizou, JI;
Bradburn, A;
Kanu, N;
Purewal, S;
Da Costa, C;
Bonnet, D;
(2016)
Perturbed hematopoiesis in mice lacking ATMIN.
Blood
, 128
(16)
pp. 2017-2021.
10.1182/blood-2015-09-672980.
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Attard, G;
Antonarakis, ES;
(2016)
Prostate cancer: AR aberrations and resistance to abiraterone or enzalutamide.
Nature Reviews Urology
, 13
(12)
pp. 697-698.
10.1038/nrurol.2016.212.
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B
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Bendell, JC;
Patel, MR;
Yoshida, K;
Seraj, J;
Weaver, R;
Lemech, C;
Todaro, TG;
... Arkenau, H-T; + view all
(2016)
Phase 1 study of cardiac safety of TAS-102 in patients with advanced solid tumors.
Cancer Chemother Pharmacol
, 77
(6)
pp. 1275-1283.
10.1007/s00280-016-3031-9.
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Bentham, RB;
(2016)
A bioinfomatic analysis of the role of mitochondrial biogenesis in human pathologies.
Doctoral thesis , UCL (University College London).
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Bentzen, AK;
Marquard, AM;
Lyngaa, R;
Saini, SK;
Ramskov, S;
Donia, M;
Such, L;
... Hadrup, SR; + view all
(2016)
Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes.
Nature Biotechnology
, 34
(10)
pp. 1037-1045.
10.1038/nbt.3662.
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Braso-Maristany, F;
Filosto, S;
Catchpole, S;
Marlow, R;
Quist, J;
Francesch-Domenech, E;
Plumb, DA;
... Tutt, AN; + view all
(2016)
PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.
Nature Medicine
, 22
(11)
pp. 1303-1313.
10.1038/nm.4198.
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C
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Campbell, J;
Ryan, CJ;
Brough, R;
Bajrami, I;
Pemberton, HN;
Chong, IY;
Costa-Cabral, S;
... Lord, CJ; + view all
(2016)
Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.
Cell Reports
, 14
(10)
pp. 2490-2501.
10.1016/j.celrep.2016.02.023.
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Carter, T;
Mulholland, P;
Chester, K;
(2016)
Antibody-targeted nanoparticles for cancer treatment.
Immunotherapy
, 8
(8)
pp. 941-958.
10.2217/imt.16.11.
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Carter, T;
Shawy, H;
Cohn-Brown, D;
Chester, K;
Mulholland, P;
(2016)
Ipilimumab and Bevacizumab in Glioblastoma.
Clinical Oncology
, 28
(10)
pp. 622-626.
10.1016/j.clon.2016.04.042.
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Castillo, SD;
Tzouanacou, E;
Zaw-Thin, M;
Berenjeno, IM;
Parker, VE;
Chivite, I;
Milà-Guasch, M;
... Vanhaesebroeck, B; + view all
(2016)
Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans.
Science Translational Medicine
, 8
(332)
, Article 332ra43. 10.1126/scitranslmed.aad9982.
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Castillo, SD;
Vanhaesebroeck, B;
Sebire, NJ;
(2016)
Phosphoinositide 3-kinase: a new kid on the block in vascular anomalies.
The Journal of Pathology
, 240
(4)
pp. 387-396.
10.1002/path.4802.
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Chakravarthy, A;
Henderson, S;
Thirdborough, SM;
Ottensmeier, CH;
Su, X;
Lechner, M;
Feber, A;
... Fenton, TR; + view all
(2016)
Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx.
Journal Of Clinical Oncology
, 34
(34)
pp. 4132-4141.
10.1200/JCO.2016.68.2955.
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Chatterjee, M;
Turner, DC;
Felip, E;
Lena, H;
Cappuzzo, F;
Horn, L;
Garon, EB;
... Flotten, O; + view all
(2016)
Systematic evaluation of pembrolizumab dosing in patients with advanced non-small-cell lung cancer.
Annals of Oncology
, 27
(7)
pp. 1291-1298.
10.1093/annonc/mdw174.
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Childs, A;
Kirkwood, A;
Edeline, J;
Tu, VL;
Watkins, J;
Lamarca, A;
Alrifai, D;
... Meyer, T; + view all
(2016)
Ki-67 index and response to chemotherapy in patients with neuroendocrine tumours.
Endocrine-Related Cancer
, 23
(7)
pp. 563-570.
10.1530/ERC-16-0099.
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Childs, A;
Vesely, C;
Ensell, L;
Lowe, H;
Luong, TV;
Caplin, ME;
Toumpanakis, C;
... Meyer, T; + view all
(2016)
Expression of somatostatin receptors 2 and 5 in circulating tumour cells from patients with neuroendocrine tumours.
British Journal of Cancer
, 115
(12)
pp. 1540-1547.
10.1038/bjc.2016.377.
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Chung, R;
Maulik, A;
Hamarneh, A;
Hochhauser, D;
Hausenloy, DJ;
Walker, JM;
Yellon, DM;
(2016)
Effect of Remote Ischaemic Conditioning in ONCology patients undergoing chemotherapy: rationale and design of the ERIC-ONC study - a single-center, blinded, randomized controlled trial.
Clinical Cardiology
, 39
(2)
pp. 72-82.
10.1002/clc.22507.
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Coulter, TI;
Chandra, A;
Bacon, CM;
Babar, J;
Curtis, J;
Screaton, N;
Goodlad, JR;
... Cant, AJ; + view all
(2016)
Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study.
J Allergy Clin Immunol
10.1016/j.jaci.2016.06.021.
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Crockford, AJ;
(2016)
Deciphering tetraploid tolerance.
Doctoral thesis , UCL (University College London).
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Crowley, C;
Klanrit, P;
Butler, CR;
Varanou, A;
Platé, M;
Hynds, RE;
Chambers, RC;
... Janes, SM; + view all
(2016)
Surface modification of a POSS-nanocomposite material to enhance cellular integration of a synthetic bioscaffold.
Biomaterials
, 83
pp. 283-293.
10.1016/j.biomaterials.2016.01.005.
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D
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Dillon, M;
Ellis, S;
Grove, L;
McLellan, L;
Clack, G;
Smith, S;
Laude, J;
... Harrington, K; + view all
(2016)
PATRIOT: A phase I study to assess the tolerability, safety and biological effects of a specific ataxia telangiectasia and Rad3-related (ATR) inhibitor (AZD6738) as a single agent and in combination with palliative radiation therapy in patients with solid tumours.
Presented at: ASCO 2016 Annual Meeting: Poster Session, Developmental Therapeutics - Clinical Pharmacology and Experimental Therapeutics, Chicago.
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Dirix, L;
Swaisland, H;
Verheul, HMW;
Rottey, S;
Leunen, K;
Jerusalem, G;
Rolfo, C;
... Plummer, R; + view all
(2016)
Effect of Itraconazole and Rifampin on the Pharmacokinetics of Olaparib in Patients With Advanced Solid Tumors: Results of Two Phase I Open-label Studies.
Clinical Therapeutics
, 38
(10)
pp. 2286-2299.
10.1016/j.clinthera.2016.08.010.
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Drummond, CJ;
Esfandiari, A;
Liu, J;
Lu, X;
Hutton, C;
Jackson, J;
Bennaceur, K;
... Lunec, J; + view all
(2016)
TP53 mutant MDM2-amplified cell lines selected for resistance to MDM2-p53 binding antagonists retain sensitivity to ionizing radiation.
Oncotarget
, 7
(29)
pp. 46203-46218.
10.18632/oncotarget.10073.
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E
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Edeline, J;
Blanc, JF;
Johnson, P;
Campillo-Gimenez, B;
Ross, P;
Ma, YT;
King, J;
... Meyer, T; + view all
(2016)
A multicentre comparison between Child Pugh and Albumin-Bilirubin scores in patients treated with sorafenib for Hepatocellular Carcinoma.
Liver International
, 36
(12)
pp. 1821-1828.
10.1111/liv.13170.
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Eminowicz, GKD;
(2016)
Standardisation and optimisation of radical radiotherapy for cervical cancer.
Doctoral thesis , UCL (University College London).
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Esfandiari, A;
Hawthorne, TA;
Nakjang, S;
Lunec, J;
(2016)
Chemical Inhibition of Wild-Type p53-Induced Phosphatase 1 (WIP1/PPM1D) by GSK2830371 Potentiates the Sensitivity to MDM2 Inhibitors in a p53-Dependent Manner.
Molecular Cancer Therapeutics
, 15
(3)
pp. 379-391.
10.1158/1535-7163.MCT-15-0651.
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Evans, IC;
Barnes, JL;
Garner, IM;
Pearce, DR;
Maher, TM;
Shi-Wen, X;
Renzoni, EA;
... McAnulty, RJ; + view all
(2016)
Epigenetic Regulation of Cyclooxygenase-2 by methylation of c8orf4 in Pulmonary Fibrosis.
Clinical Science
, 130
(8)
pp. 575-586.
10.1042/CS20150697.
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F
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Flores-Borja, F;
Irshad, S;
Gordon, P;
Wong, F;
Sheriff, I;
Tutt, A;
Ng, T;
(2016)
Crosstalk between Innate Lymphoid Cells and Other Immune Cells in the Tumor Microenvironment.
Journal of Immunology Research
, Article 7803091. 10.1155/2016/7803091.
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Flynn, MJ;
(2016)
Mechanistic and pharmacodynamic studies of ADCT-301, an Antibody Drug Conjugate targeting CD25-expressing haematological malignancies.
Doctoral thesis , UCL (University College London).
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Flynn, MJ;
Zammarchi, F;
Tyrer, PC;
Akarca, AU;
Janghra, N;
Britten, CE;
Havenith, CEG;
... Hartley, JA; + view all
(2016)
ADCT-301, a Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody-Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies.
Molecular Cancer Therapeutics
, 15
(11)
pp. 2709-2721.
10.1158/1535-7163.MCT-16-0233.
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Forster, M;
Mendes, R;
Harrington, K;
Guerrero-Urbano, T;
Baines, H;
Spanswick, V;
Ensell, L;
... Beare, S; + view all
(2016)
A phase I study of olaparib in addition to cisplatin-based concurrent chemoradiotherapy for patients with high risk locally advanced squamous cell carcinoma of the head and neck (HNSCC).
Presented at: 2016 ASCO Annual Meeting, Chicago, IL, USA.
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Foxall, E;
Pipili, A;
Jones, GE;
Wells, CM;
(2016)
Significance of kinase activity in the dynamic invadosome.
European Journal of Cell Biology
, 95
(11)
pp. 483-492.
10.1016/j.ejcb.2016.07.002.
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G
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Gillessen, S;
Omlin, A;
Attard, G;
de Bono, JS;
Efstathiou, E;
Fizazi, K;
Halabi, S;
... Tombal, B; + view all
(2016)
Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015.
Annals of Oncology
, 26
pp. 1589-1604.
10.1093/annonc/mdw180.
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Goh, G;
Schmid, R;
Guiver, K;
Arpornwirat, W;
Chitapanarux, I;
Ganju, V;
Im, SA;
... Swanton, C; + view all
(2016)
Clonal Evolutionary Analysis during HER2 Blockade in HER2-Positive Inflammatory Breast Cancer: A Phase II Open-Label Clinical Trial of Afatinib +/- Vinorelbine.
PLOS Med
, 13
(12)
, Article e1002136. 10.1371/journal.pmed.1002136.
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H
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Hall, AR;
Burke, N;
Dongworth, RK;
Kalkhoran, SB;
Dyson, A;
Vicencio, JM;
Dorn Ii, GW;
... Hausenloy, DJ; + view all
(2016)
Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction.
Cell Death and Disease
, 7
, Article e2238. 10.1038/cddis.2016.139.
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Harrington, K;
Forster, M;
Dillon, M;
Grove, L;
Adeleke, S;
Chen, S;
Diamond, J;
... Greenberg, J; + view all
(2016)
Patritumab or Placebo Plus Cetuximab and Platinum-Based Therapy in Squamous Cell Carcinoma of the Head and Neck (SCCHN): a Phase 2 Study.
Presented at: ASCO 2016 Annual Meeting: Poster Session, Head and Neck Cancer, Chicago.
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Hiley, CT;
Le Quesne, J;
Santis, G;
Sharpe, R;
De Castro, DG;
Middleton, G;
Swanton, C;
(2016)
Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease.
The Lancet
, 388
(10048)
pp. 1002-1011.
10.1016/S0140-6736(16)31340-X.
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Hopper, C;
Jerjes, W;
Sultan, A;
Forster, M;
carnell, D;
Simeon, C;
Berg, K;
... Hamdoon, Z; + view all
(2016)
Disulfonated tetraphenyl chlorin (TPCS2a)–induced photochemical internalisation of bleomycin in patients with solid malignancies: A first-in-man phase I dose escalation clinical trial.
The Lancet Oncology
, 17
(9)
pp. 1217-1229.
10.1016/S1470-2045(16)30224-8.
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Hughes, A;
Landers, D;
Arkenau, H-T;
Shah, S;
Stephens, R;
Mahal, A;
Simmons, M;
... Royle, J; + view all
(2016)
Development and Evaluation of a New Technological Way of Engaging Patients and Enhancing Understanding of Drug Tolerability in Early Clinical Development: PROACT.
Advances in Therapy
, 33
(6)
pp. 1012-1024.
10.1007/s12325-016-0335-4.
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Hynds, RE;
(2016)
Characterisation of cultured airway basal cells to understand their role in human lung disease.
Doctoral thesis , UCL (University College London).
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Hynds, RE;
Butler, CR;
Janes, SM;
Giangreco, A;
(2016)
Expansion of Human Airway Basal Stem Cells and Their Differentiation as 3D Tracheospheres.
Organoids: Methods in Molecular Biology
, 1576
pp. 43-53.
10.1007/7651_2016_5.
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J
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James, ND;
Sydes, MR;
Clarke, NW;
Mason, MD;
Dearnaley, DP;
Spears, MR;
Ritchie, AW;
... STAMPEDE investigators; + view all
(2016)
Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial.
Lancet
, 387
(10024)
pp. 1163-1177.
10.1016/S0140-6736(15)01037-5.
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Johnston, EW;
Pye, H;
Bonet Carne, E;
Panagiotaki, E;
Patel, D;
Galazi, M;
Heavey, S;
... Punwani, S; + view all
(2016)
INNOVATE: A prospective cohort study combining serum and urinary biomarkers with novel diffusion-weighted magnetic resonance imaging for the prediction and characterization of prostate cancer.
BMC Cancer
, 16
(816)
10.1186/s12885-016-2856-2.
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K
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Kanu, N;
Cerone, MA;
Goh, G;
Zalmas, L-P;
Bartkova, J;
Dietzen, M;
McGranahan, N;
... Swanton, C; + view all
(2016)
DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer.
Genome Biology
, 17
, Article 185. 10.1186/s13059-016-1042-9.
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Kinna, A;
Tolner, B;
Rota, EM;
Titchener-Hooker, N;
Nesbeth, D;
Chester, K;
(2016)
IMAC capture of recombinant protein from unclarified mammalian cell feed streams.
Biotechnology and Bioengineering
, 113
(1)
pp. 130-140.
10.1002/bit.25705.
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Konecny, G;
Kristeleit, RS;
(2016)
PARP inhibitors for BRCA1/2-mutated and sporadic ovarian cancer: current practice and future directions.
British Journal of Cancer
, 115
pp. 1157-1173.
10.1038/bjc.2016.311.
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Kotwinski, PJ;
Smith, G;
Cooper, J;
Sanders, J;
Ma, L;
Teis, A;
Kotwinski, D;
... Breast cancer Early disease: Toxicity from Therapy with Epirubic; + view all
(2016)
Body Surface Area and Baseline Blood Pressure Predict Subclinical Anthracycline Cardiotoxicity in Women Treated for Early Breast Cancer.
PLOS One
, 11
(12)
, Article e0165262. 10.1371/journal.pone.0165262.
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Kristeleit, RS;
Miller, RE;
Kohn, EC;
(2016)
Gynecologic Cancers: Emerging Novel Strategies for Targeting DNA Repair Deficiency.
American Society of Clinical Oncology Educational Book
, 2016
10.14694/EDBK_159086.
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Kularatne, B;
Arora, R;
Elshstein, G;
Guppy, N;
Kirkwood, A;
Meyer, T;
Kristeleit, RS;
(2016)
Immunohistochemistry (IHC) evaluation of a novel 4-protein prognostic and predictive biomarker panel in endometrial cancer (EC).
In:
Abstract Book of the 41st ESMO Congress (ESMO 2016), 7-11 October 2016, Copenhagen, Denmar.
Oxford University Press (OUP): Policy A1
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L
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Lampada, A;
(2016)
Targeting autophagy in colorectal cancer.
Doctoral thesis , UCL (University College London).
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Laskaratos, F-M;
Walker, M;
Naik, K;
Maragkoudakis, E;
Oikonomopoulos, N;
Grant, L;
Meyer, T;
... Toumpanakis, C; + view all
(2016)
Predictive factors of antiproliferative activity of octreotide LAR as first-line therapy for advanced neuroendocrine tumours.
British Journal of Cancer
, 115
(11)
pp. 1321-1327.
10.1038/bjc.2016.349.
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Lawson, C;
Vicencio, JM;
Yellon, DM;
Davidson, SM;
(2016)
Microvesicles and exosomes: new players in metabolic and cardiovascular disease.
Journal of Endocrinology
, 228
(2)
R57-R71.
10.1530/JOE-15-0201.
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Ledermann, JA;
Drew, Y;
Kristeleit, RS;
(2016)
Homologous recombination deficiency and ovarian cancer.
European Journal of Cancer
, 60
pp. 49-58.
10.1016/j.ejca.2016.03.005.
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Lee, AJX;
Benamore, R;
Hofer, M;
Chitnis, M;
(2016)
Leptomeningeal carcinomatosis in non-small-cell lung cancer: initial response to erlotinib followed by relapse despite continuing radiological resolution of disease.
Oxford Medical Case Reports
, 2016
(9)
, Article omw069. 10.1093/omcr/omw069.
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Lee, SM;
Falzon, M;
Blackhall, F;
Spicer, J;
Nicolson, M;
Chaudhuri, A;
Middleton, G;
... Hackshaw, A; + view all
(2016)
Randomized Prospective Biomarker Trial of ERCC1 for Comparing Platinum and Nonplatinum Therapy in Advanced Non-Small-Cell Lung Cancer: ERCC1 Trial (ET).
Journal of Clinical Oncology
, 35
(4)
pp. 402-411.
10.1200/JCO.2016.68.1841.
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Lemech, CR;
Ensell, L;
Paterson, JC;
Eminowicz, G;
Lowe, H;
Arora, R;
Arkenau, H-T;
... Kristeleit, RS; + view all
(2016)
Enumeration and Molecular Characterisation of Circulating Tumour Cells in Endometrial Cancer.
Oncology
, 91
(1)
pp. 48-54.
10.1159/000445999.
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Lopez-Guadamillas, E;
Fernandez-Marcos, PJ;
Pantoja, C;
Muñoz-Martin, M;
MartÃnez, D;
Gómez-López, G;
Campos-Olivas, R;
... Serrano, M; + view all
(2016)
p21(Cip1) plays a critical role in the physiological adaptation to fasting through activation of PPARα.
Sci Rep
, 6
, Article 34542. 10.1038/srep34542.
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Lopez-Guadamillas, E;
Muñoz-Martin, M;
Martinez, S;
Pastor, J;
Fernandez-Marcos, PJ;
Serrano, M;
(2016)
PI3Kα inhibition reduces obesity in mice.
Aging
, 8
(11)
pp. 2747-2753.
10.18632/aging.101075.
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Lorente, D;
Omlin, A;
Zafeiriou, Z;
Nava-Rodrigues, D;
Pérez-López, R;
Pezaro, C;
Mehra, N;
... de Bono, J; + view all
(2016)
Castration-Resistant Prostate Cancer Tissue Acquisition From Bone Metastases for Molecular Analyses.
Clinical Genitourinary Cancer
, 14
(6)
pp. 485-493.
10.1016/j.clgc.2016.04.016.
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M
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Mak, G;
Moschetta, M;
Arkenau, H-T;
(2016)
Reporting incidental germline variants in the context of day-to-day somatic genomic profiling.
Annals of Oncology
, 27
(5)
pp. 758-759.
10.1093/annonc/mdw078.
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Mandair, D;
Vesely, C;
Ensell, L;
Lowe, H;
Spanswick, V;
Hartley, JA;
Caplin, ME;
(2016)
A comparison of CellCollector with CellSearch in patients with neuroendocrine tumours.
Endocrine-Related Cancer
, 23
(10)
L29-L32.
10.1530/ERC-16-0201.
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Marina, NM;
Smeland, S;
Bielack, SS;
Bernstein, M;
Jovic, G;
Krailo, MD;
Hook, JM;
... Whelan, JS; + view all
(2016)
Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial.
The Lancet Oncology
, 17
(10)
pp. 1396-1408.
10.1016/S1470-2045(16)30214-5.
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Maughan, E;
Lesage, F;
Butler, CR;
Hynds, RE;
Hewitt, R;
Janes, SM;
Deprest, JA;
(2016)
Airway tissue engineering for congenital laryngotracheal disease.
Seminars in Pediatric Surgery
, 25
(3)
pp. 186-190.
10.1053/j.sempedsurg.2016.02.012.
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Miller, RE;
Brown, NE;
Speirs, A;
Shaw, HM;
Adeleke, S;
Gougis, P;
Bennett, P;
... Kristeleit, RS; + view all
(2016)
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